JP2003502669A - 組織の母集団を表わす指標を包含するデータベースを使用して組織をプロファイルし分類する方法 - Google Patents
組織の母集団を表わす指標を包含するデータベースを使用して組織をプロファイルし分類する方法Info
- Publication number
- JP2003502669A JP2003502669A JP2001505187A JP2001505187A JP2003502669A JP 2003502669 A JP2003502669 A JP 2003502669A JP 2001505187 A JP2001505187 A JP 2001505187A JP 2001505187 A JP2001505187 A JP 2001505187A JP 2003502669 A JP2003502669 A JP 2003502669A
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- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
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Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S128/00—Surgery
- Y10S128/92—Computer assisted medical diagnostics
- Y10S128/923—Computer assisted medical diagnostics by comparison of patient data to other data
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S707/00—Data processing: database and file management or data structures
- Y10S707/99931—Database or file accessing
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S707/00—Data processing: database and file management or data structures
- Y10S707/99931—Database or file accessing
- Y10S707/99933—Query processing, i.e. searching
- Y10S707/99936—Pattern matching access
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S707/00—Data processing: database and file management or data structures
- Y10S707/99931—Database or file accessing
- Y10S707/99937—Sorting
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S707/00—Data processing: database and file management or data structures
- Y10S707/99941—Database schema or data structure
- Y10S707/99943—Generating database or data structure, e.g. via user interface
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S707/00—Data processing: database and file management or data structures
- Y10S707/99941—Database schema or data structure
- Y10S707/99944—Object-oriented database structure
- Y10S707/99945—Object-oriented database structure processing
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Bioinformatics & Computational Biology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/338,909 | 1999-06-23 | ||
| US09/338,909 US6611833B1 (en) | 1999-06-23 | 1999-06-23 | Methods for profiling and classifying tissue using a database that includes indices representative of a tissue population |
| PCT/US2000/017391 WO2000079269A1 (en) | 1999-06-23 | 2000-06-23 | Methods for profiling and classifying tissue using a database that includes indices representative of a tissue population |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2003502669A true JP2003502669A (ja) | 2003-01-21 |
| JP2003502669A5 JP2003502669A5 (https=) | 2007-08-30 |
Family
ID=23326653
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001505187A Pending JP2003502669A (ja) | 1999-06-23 | 2000-06-23 | 組織の母集団を表わす指標を包含するデータベースを使用して組織をプロファイルし分類する方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US6611833B1 (https=) |
| EP (1) | EP1194775A4 (https=) |
| JP (1) | JP2003502669A (https=) |
| AU (1) | AU5888000A (https=) |
| CA (1) | CA2389220C (https=) |
| WO (1) | WO2000079269A1 (https=) |
Families Citing this family (98)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6993170B2 (en) * | 1999-06-23 | 2006-01-31 | Icoria, Inc. | Method for quantitative analysis of blood vessel structure |
| US20020087511A1 (en) * | 1999-09-02 | 2002-07-04 | Johnson Peter C. | Methods for profiling and manufacturing tissue using a database that includes indices representative of a tissue population |
| US7613571B2 (en) * | 2000-07-28 | 2009-11-03 | Doyle Michael D | Method and system for the multidimensional morphological reconstruction of genome expression activity |
| JP2002172117A (ja) * | 2000-09-05 | 2002-06-18 | Fuji Photo Film Co Ltd | 光断層画像診断情報出力装置 |
| DE60141090D1 (de) | 2000-10-30 | 2010-03-04 | Gen Hospital Corp | Optische systeme zur gewebeanalyse |
| US9295391B1 (en) | 2000-11-10 | 2016-03-29 | The General Hospital Corporation | Spectrally encoded miniature endoscopic imaging probe |
| WO2002088705A2 (en) | 2001-05-01 | 2002-11-07 | The General Hospital Corporation | Method and apparatus for determination of atherosclerotic plaque type by measurement of tissue optical properties |
| KR100452748B1 (ko) * | 2001-05-08 | 2004-10-12 | 유닉스전자주식회사 | 전자 혈압계를 이용한 심전도 측정 방법 |
| US20030149535A1 (en) * | 2001-07-17 | 2003-08-07 | Yukio Sudo | Method for quantifying nucleic acid by cell counting |
| US7355716B2 (en) | 2002-01-24 | 2008-04-08 | The General Hospital Corporation | Apparatus and method for ranging and noise reduction of low coherence interferometry LCI and optical coherence tomography OCT signals by parallel detection of spectral bands |
| US8054468B2 (en) | 2003-01-24 | 2011-11-08 | The General Hospital Corporation | Apparatus and method for ranging and noise reduction of low coherence interferometry LCI and optical coherence tomography OCT signals by parallel detection of spectral bands |
| AU2004206998B2 (en) * | 2003-01-24 | 2009-12-17 | The General Hospital Corporation | System and method for identifying tissue using low-coherence interferometry |
| CA2519937C (en) | 2003-03-31 | 2012-11-20 | Guillermo J. Tearney | Speckle reduction in optical coherence tomography by path length encoded angular compounding |
| EP2280260B1 (en) | 2003-06-06 | 2017-03-08 | The General Hospital Corporation | Process and apparatus for a wavelength tuned light source |
| US20050014131A1 (en) * | 2003-07-16 | 2005-01-20 | Cytokinetics, Inc. | Methods and apparatus for investigating side effects |
| US7483554B2 (en) * | 2003-11-17 | 2009-01-27 | Aureon Laboratories, Inc. | Pathological tissue mapping |
| US7467119B2 (en) * | 2003-07-21 | 2008-12-16 | Aureon Laboratories, Inc. | Systems and methods for treating, diagnosing and predicting the occurrence of a medical condition |
| US7505948B2 (en) * | 2003-11-18 | 2009-03-17 | Aureon Laboratories, Inc. | Support vector regression for censored data |
| JP5567246B2 (ja) | 2003-10-27 | 2014-08-06 | ザ ジェネラル ホスピタル コーポレイション | 周波数ドメイン干渉測定を利用して光学撮像を実行する方法および装置 |
| TW200532523A (en) * | 2004-02-27 | 2005-10-01 | Aureon Biosciences Corp | Methods and systems for predicting occurrence of an event |
| WO2005117534A2 (en) | 2004-05-29 | 2005-12-15 | The General Hospital Corporation | Process, system and software arrangement for a chromatic dispersion compensation using reflective layers in optical coherence tomography (oct) imaging |
| AU2005270037B2 (en) | 2004-07-02 | 2012-02-09 | The General Hospital Corporation | Endoscopic imaging probe comprising dual clad fibre |
| EP1782020B1 (en) | 2004-08-06 | 2012-10-03 | The General Hospital Corporation | Process, system and software arrangement for determining at least one location in a sample using an optical coherence tomography |
| WO2006020627A1 (en) * | 2004-08-11 | 2006-02-23 | Aureon Laboratories, Inc. | Systems and methods for automated diagnosis and grading of tissue images |
| WO2006024015A1 (en) | 2004-08-24 | 2006-03-02 | The General Hospital Corporation | Method and apparatus for imaging of vessel segments |
| WO2006024014A2 (en) | 2004-08-24 | 2006-03-02 | The General Hospital Corporation | Process, system and software arrangement for measuring a mechanical strain and elastic properties of a sample |
| JP5215664B2 (ja) | 2004-09-10 | 2013-06-19 | ザ ジェネラル ホスピタル コーポレイション | 光学コヒーレンス撮像のシステムおよび方法 |
| JP4997112B2 (ja) | 2004-09-29 | 2012-08-08 | ザ ジェネラル ホスピタル コーポレイション | 少なくとも１つの電磁放射を伝送させるための装置およびその製造方法 |
| EP2278265A3 (en) | 2004-11-24 | 2011-06-29 | The General Hospital Corporation | Common-Path Interferometer for Endoscopic OCT |
| US8922781B2 (en) | 2004-11-29 | 2014-12-30 | The General Hospital Corporation | Arrangements, devices, endoscopes, catheters and methods for performing optical imaging by simultaneously illuminating and detecting multiple points on a sample |
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| EP1889037A2 (en) | 2005-06-01 | 2008-02-20 | The General Hospital Corporation | Apparatus, method and system for performing phase-resolved optical frequency domain imaging |
| ATE484727T1 (de) | 2005-08-09 | 2010-10-15 | Gen Hospital Corp | Gerät und verfahren zur durchführung von polarisationsbasierter quadraturdemodulation bei optischer kohärenztomographie |
| JP4647442B2 (ja) * | 2005-09-14 | 2011-03-09 | 独立行政法人情報通信研究機構 | データ表示装置、データ表示方法およびデータ表示プログラム |
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| US7783092B2 (en) * | 2006-01-17 | 2010-08-24 | Illinois Institute Of Technology | Method for enhancing diagnostic images using vessel reconstruction |
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| US8249696B2 (en) | 2007-12-19 | 2012-08-21 | Depuy Spine, Inc. | Smart pedicle tool |
| US7898656B2 (en) | 2008-04-30 | 2011-03-01 | The General Hospital Corporation | Apparatus and method for cross axis parallel spectroscopy |
| EP2274572A4 (en) | 2008-05-07 | 2013-08-28 | Gen Hospital Corp | SYSTEM, METHOD AND COMPUTER MEDIUM FOR TRACKING A VASCULAR MOVEMENT IN A THREE-DIMENSIONAL CORONARTERTERIC MICROSCOPY |
| KR100963689B1 (ko) | 2008-05-13 | 2010-06-15 | 대한민국 | 인체조직 분류 방법 |
| EP2288948A4 (en) | 2008-06-20 | 2011-12-28 | Gen Hospital Corp | Fused fiber optic coupler arrangement and method for use thereof |
| WO2010009136A2 (en) | 2008-07-14 | 2010-01-21 | The General Hospital Corporation | Apparatus and methods for color endoscopy |
| US8801635B2 (en) * | 2008-10-03 | 2014-08-12 | Hlz Innovation, Llc | Adjustable pneumatic supporting surface |
| ES2957932T3 (es) | 2008-12-10 | 2024-01-30 | Massachusetts Gen Hospital | Sistemas, aparatos y procedimientos para ampliar el rango de profundidad de imagen de tomografía de coherencia óptica mediante submuestreo óptico |
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| JP2012515930A (ja) | 2009-01-26 | 2012-07-12 | ザ ジェネラル ホスピタル コーポレーション | 広視野の超解像顕微鏡を提供するためのシステム、方法及びコンピューターがアクセス可能な媒体 |
| CN104134928A (zh) | 2009-02-04 | 2014-11-05 | 通用医疗公司 | 利用高速光学波长调谐源的设备和方法 |
| US11490826B2 (en) | 2009-07-14 | 2022-11-08 | The General Hospital Corporation | Apparatus, systems and methods for measuring flow and pressure within a vessel |
| US8052622B2 (en) * | 2009-09-02 | 2011-11-08 | Artann Laboratories Inc | Methods for characterizing vaginal tissue elasticity |
| WO2011100430A2 (en) | 2010-02-10 | 2011-08-18 | Kickstart International, Inc. | Human-powered irrigation pump |
| HRP20201813T1 (hr) | 2010-03-05 | 2021-03-19 | The General Hospital Corporation | Uređaj za pružanje elektromagnetnog zračenja na uzorak |
| US9069130B2 (en) | 2010-05-03 | 2015-06-30 | The General Hospital Corporation | Apparatus, method and system for generating optical radiation from biological gain media |
| EP2575597B1 (en) | 2010-05-25 | 2022-05-04 | The General Hospital Corporation | Apparatus for providing optical imaging of structures and compositions |
| WO2011150069A2 (en) | 2010-05-25 | 2011-12-01 | The General Hospital Corporation | Apparatus, systems, methods and computer-accessible medium for spectral analysis of optical coherence tomography images |
| WO2011153434A2 (en) | 2010-06-03 | 2011-12-08 | The General Hospital Corporation | Apparatus and method for devices for imaging structures in or at one or more luminal organs |
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| US20120207360A1 (en) * | 2011-02-11 | 2012-08-16 | Courosh Mehanian | Systems and Methods for Object Identification |
| JP2014523536A (ja) | 2011-07-19 | 2014-09-11 | ザ ジェネラル ホスピタル コーポレイション | 光コヒーレンストモグラフィーにおいて偏波モード分散補償を提供するためのシステム、方法、装置およびコンピュータアクセス可能な媒体 |
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| US10013527B2 (en) | 2016-05-02 | 2018-07-03 | Aranz Healthcare Limited | Automatically assessing an anatomical surface feature and securely managing information related to the same |
| US11116407B2 (en) | 2016-11-17 | 2021-09-14 | Aranz Healthcare Limited | Anatomical surface assessment methods, devices and systems |
| US11903723B2 (en) | 2017-04-04 | 2024-02-20 | Aranz Healthcare Limited | Anatomical surface assessment methods, devices and systems |
| WO2020234653A1 (en) | 2019-05-20 | 2020-11-26 | Aranz Healthcare Limited | Automated or partially automated anatomical surface assessment methods, devices and systems |
Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH05126746A (ja) * | 1991-11-07 | 1993-05-21 | Nikon Corp | イオン濃度の定量装置および定量方法 |
| JPH0694706A (ja) * | 1992-09-10 | 1994-04-08 | Sumitomo Metal Ind Ltd | 病理画像検査支援装置 |
| JPH06229723A (ja) * | 1992-10-16 | 1994-08-19 | Becton Dickinson & Co | 組織切片厚みを測定する方法および装置 |
| JPH07506897A (ja) * | 1992-01-17 | 1995-07-27 | ヴァージニア コモンウェルス ユニヴァーシティ | 血液凝固および溶解期間中に凝血弾性係数，収縮力発生および赤血球柔軟性を評価する装置および方法 |
| WO1998049969A1 (en) * | 1997-05-08 | 1998-11-12 | Organogenesis Inc. | Chemical cleaning of biological material |
| JPH1119077A (ja) * | 1997-06-30 | 1999-01-26 | Konica Corp | 放射線画像における腫瘤影の検出方法及び装置 |
| JPH11501741A (ja) * | 1995-01-27 | 1999-02-09 | インサイト ファーマシューティカルズ インク． | 微生物学的データを保存し解析するコンピュータシステム |
| JPH11507133A (ja) * | 1995-06-07 | 1999-06-22 | インフォサイト・インコーポレーテッド | 人間の組織及び細胞の赤外線分析による病気の診断を行うためのシステム及び方法 |
| JP2001509816A (ja) * | 1997-03-12 | 2001-07-24 | ザ レジェンツ オブ ザ ユニバーシティー オブ カリフォルニア | 血管新生内皮細胞を標的とした陽イオン脂質組成物 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5016173A (en) * | 1989-04-13 | 1991-05-14 | Vanguard Imaging Ltd. | Apparatus and method for monitoring visually accessible surfaces of the body |
| US5235522A (en) | 1990-10-10 | 1993-08-10 | Cell Analysis Systems, Inc. | Method and apparatus for automated analysis of biological specimens |
| US5506098A (en) * | 1991-09-04 | 1996-04-09 | Daikin Industries, Ltd. | In situ hybridization method |
| EP0649282B1 (en) * | 1992-07-03 | 1998-09-30 | NEWMAN, Paul Bernard David | A quality control and grading system for meat |
| US6026174A (en) * | 1992-10-14 | 2000-02-15 | Accumed International, Inc. | System and method for automatically detecting malignant cells and cells having malignancy-associated changes |
| US5785663A (en) * | 1992-12-21 | 1998-07-28 | Artann Corporation | Method and device for mechanical imaging of prostate |
| US5987346A (en) * | 1993-02-26 | 1999-11-16 | Benaron; David A. | Device and method for classification of tissue |
| US5685313A (en) * | 1994-05-31 | 1997-11-11 | Brain Monitor Ltd. | Tissue monitor |
| US5640453A (en) * | 1994-08-11 | 1997-06-17 | Stanford Telecommunications, Inc. | Universal interactive set-top controller for downloading and playback of information and entertainment services |
| AU3490695A (en) | 1994-09-20 | 1996-04-09 | Neopath, Inc. | Cytological slide scoring apparatus |
| US5713364A (en) * | 1995-08-01 | 1998-02-03 | Medispectra, Inc. | Spectral volume microprobe analysis of materials |
| DE19616997A1 (de) | 1996-04-27 | 1997-10-30 | Boehringer Mannheim Gmbh | Verfahren zur automatisierten mikroskopunterstützten Untersuchung von Gewebeproben oder Körperflüssigkeitsproben |
| US5891619A (en) | 1997-01-14 | 1999-04-06 | Inphocyte, Inc. | System and method for mapping the distribution of normal and abnormal cells in sections of tissue |
| US6081612A (en) * | 1997-02-28 | 2000-06-27 | Electro Optical Sciences Inc. | Systems and methods for the multispectral imaging and characterization of skin tissue |
| US5840534A (en) * | 1997-05-09 | 1998-11-24 | Incyte Pharmaceuticals, Inc. | Human SMT3-like protein |
| US6104835A (en) | 1997-11-14 | 2000-08-15 | Kla-Tencor Corporation | Automatic knowledge database generation for classifying objects and systems therefor |
| US6238342B1 (en) | 1998-05-26 | 2001-05-29 | Riverside Research Institute | Ultrasonic tissue-type classification and imaging methods and apparatus |
-
1999
- 1999-06-23 US US09/338,909 patent/US6611833B1/en not_active Expired - Lifetime
-
2000
- 2000-06-23 CA CA2389220A patent/CA2389220C/en not_active Expired - Lifetime
- 2000-06-23 EP EP00944845A patent/EP1194775A4/en not_active Withdrawn
- 2000-06-23 WO PCT/US2000/017391 patent/WO2000079269A1/en not_active Ceased
- 2000-06-23 JP JP2001505187A patent/JP2003502669A/ja active Pending
- 2000-06-23 AU AU58880/00A patent/AU5888000A/en not_active Abandoned
-
2003
- 2003-08-22 US US10/646,578 patent/US20040117343A1/en not_active Abandoned
Patent Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH05126746A (ja) * | 1991-11-07 | 1993-05-21 | Nikon Corp | イオン濃度の定量装置および定量方法 |
| JPH07506897A (ja) * | 1992-01-17 | 1995-07-27 | ヴァージニア コモンウェルス ユニヴァーシティ | 血液凝固および溶解期間中に凝血弾性係数，収縮力発生および赤血球柔軟性を評価する装置および方法 |
| JPH0694706A (ja) * | 1992-09-10 | 1994-04-08 | Sumitomo Metal Ind Ltd | 病理画像検査支援装置 |
| JPH06229723A (ja) * | 1992-10-16 | 1994-08-19 | Becton Dickinson & Co | 組織切片厚みを測定する方法および装置 |
| JPH11501741A (ja) * | 1995-01-27 | 1999-02-09 | インサイト ファーマシューティカルズ インク． | 微生物学的データを保存し解析するコンピュータシステム |
| JPH11507133A (ja) * | 1995-06-07 | 1999-06-22 | インフォサイト・インコーポレーテッド | 人間の組織及び細胞の赤外線分析による病気の診断を行うためのシステム及び方法 |
| JP2001509816A (ja) * | 1997-03-12 | 2001-07-24 | ザ レジェンツ オブ ザ ユニバーシティー オブ カリフォルニア | 血管新生内皮細胞を標的とした陽イオン脂質組成物 |
| WO1998049969A1 (en) * | 1997-05-08 | 1998-11-12 | Organogenesis Inc. | Chemical cleaning of biological material |
| JPH1119077A (ja) * | 1997-06-30 | 1999-01-26 | Konica Corp | 放射線画像における腫瘤影の検出方法及び装置 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP1194775A1 (en) | 2002-04-10 |
| CA2389220C (en) | 2011-07-26 |
| WO2000079269A1 (en) | 2000-12-28 |
| AU5888000A (en) | 2001-01-09 |
| US6611833B1 (en) | 2003-08-26 |
| EP1194775A4 (en) | 2004-09-15 |
| CA2389220A1 (en) | 2000-12-28 |
| US20040117343A1 (en) | 2004-06-17 |
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