JP2003501382A - 軟骨形成性分化誘発のためのマクロライド化合物の新規用途 - Google Patents

軟骨形成性分化誘発のためのマクロライド化合物の新規用途

Info

Publication number
JP2003501382A
JP2003501382A JP2001501202A JP2001501202A JP2003501382A JP 2003501382 A JP2003501382 A JP 2003501382A JP 2001501202 A JP2001501202 A JP 2001501202A JP 2001501202 A JP2001501202 A JP 2001501202A JP 2003501382 A JP2003501382 A JP 2003501382A
Authority
JP
Japan
Prior art keywords
group
hydrogen atom
hydroxy
atom
macrolide compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2001501202A
Other languages
English (en)
Japanese (ja)
Other versions
JP2003501382A5 (cg-RX-API-DMAC10.html
Inventor
扶佐子 西垣
進 宮田
Original Assignee
藤沢薬品工業株式会社
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 藤沢薬品工業株式会社 filed Critical 藤沢薬品工業株式会社
Publication of JP2003501382A publication Critical patent/JP2003501382A/ja
Publication of JP2003501382A5 publication Critical patent/JP2003501382A5/ja
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Saccharide Compounds (AREA)
JP2001501202A 1999-06-04 2000-05-31 軟骨形成性分化誘発のためのマクロライド化合物の新規用途 Withdrawn JP2003501382A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AU0787 1999-06-04
AUPQ0787A AUPQ078799A0 (en) 1999-06-04 1999-06-04 New use
PCT/JP2000/003533 WO2000074665A2 (en) 1999-06-04 2000-05-31 New use of macrolide compounds for inducing chondrogenic differentiation

Publications (2)

Publication Number Publication Date
JP2003501382A true JP2003501382A (ja) 2003-01-14
JP2003501382A5 JP2003501382A5 (cg-RX-API-DMAC10.html) 2006-02-09

Family

ID=3814984

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001501202A Withdrawn JP2003501382A (ja) 1999-06-04 2000-05-31 軟骨形成性分化誘発のためのマクロライド化合物の新規用途

Country Status (7)

Country Link
US (1) US6489340B1 (cg-RX-API-DMAC10.html)
EP (1) EP1183028B1 (cg-RX-API-DMAC10.html)
JP (1) JP2003501382A (cg-RX-API-DMAC10.html)
AU (1) AUPQ078799A0 (cg-RX-API-DMAC10.html)
DE (1) DE60004044T2 (cg-RX-API-DMAC10.html)
ES (1) ES2202130T3 (cg-RX-API-DMAC10.html)
WO (1) WO2000074665A2 (cg-RX-API-DMAC10.html)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009509608A (ja) * 2005-09-29 2009-03-12 インファ ソシエテ アノニム 薬剤の非経口投与のためのキット

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070032853A1 (en) 2002-03-27 2007-02-08 Hossainy Syed F 40-O-(2-hydroxy)ethyl-rapamycin coated stent
AU2003901023A0 (en) * 2003-03-04 2003-03-20 Fujisawa Pharmaceutical Co., Ltd. New use
US20050118344A1 (en) 2003-12-01 2005-06-02 Pacetti Stephen D. Temperature controlled crimping
EP2182957A4 (en) * 2007-07-31 2012-07-18 Limerick Biopharma Inc PHOSPHORYLATED PYRONANALOGES AND CORRESPONDING METHODS

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE388724T1 (de) * 1998-01-08 2008-03-15 Univ Washington Methoden zur kontrolle der zelldifferenzierung und des zellwachstums durch verwendung eines fusionsproteins und eines wirkstoffes

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009509608A (ja) * 2005-09-29 2009-03-12 インファ ソシエテ アノニム 薬剤の非経口投与のためのキット

Also Published As

Publication number Publication date
AUPQ078799A0 (en) 1999-06-24
US6489340B1 (en) 2002-12-03
WO2000074665A3 (en) 2001-05-17
EP1183028B1 (en) 2003-07-23
WO2000074665A2 (en) 2000-12-14
DE60004044T2 (de) 2004-04-15
ES2202130T3 (es) 2004-04-01
DE60004044D1 (de) 2003-08-28
EP1183028A2 (en) 2002-03-06

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