JP2003500161A - インプラントの周囲の骨および／または組織への生物活性物質の送出しを確実にするためのインプラントの方法、構成、および使用 - Google Patents
インプラントの周囲の骨および／または組織への生物活性物質の送出しを確実にするためのインプラントの方法、構成、および使用Info
- Publication number
- JP2003500161A JP2003500161A JP2000620892A JP2000620892A JP2003500161A JP 2003500161 A JP2003500161 A JP 2003500161A JP 2000620892 A JP2000620892 A JP 2000620892A JP 2000620892 A JP2000620892 A JP 2000620892A JP 2003500161 A JP2003500161 A JP 2003500161A
- Authority
- JP
- Japan
- Prior art keywords
- implant
- bone
- bioactive
- release
- substance
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000007943 implant Substances 0.000 title claims abstract description 171
- 210000001519 tissue Anatomy 0.000 title claims abstract description 43
- 230000000975 bioactive effect Effects 0.000 title claims abstract description 40
- 210000000988 bone and bone Anatomy 0.000 title claims abstract description 30
- 238000000034 method Methods 0.000 title claims description 17
- 239000000463 material Substances 0.000 title abstract description 9
- 239000000126 substance Substances 0.000 claims abstract description 54
- 239000012867 bioactive agent Substances 0.000 claims description 19
- 239000003102 growth factor Substances 0.000 claims description 18
- 238000013461 design Methods 0.000 claims description 15
- 230000010354 integration Effects 0.000 claims description 10
- 229920006395 saturated elastomer Polymers 0.000 claims description 7
- 238000010276 construction Methods 0.000 claims description 5
- 239000007787 solid Substances 0.000 claims description 5
- 239000000515 collagen sponge Substances 0.000 claims description 4
- 239000004744 fabric Substances 0.000 claims description 4
- 239000000853 adhesive Substances 0.000 claims description 3
- 230000001070 adhesive effect Effects 0.000 claims description 3
- 102000004887 Transforming Growth Factor beta Human genes 0.000 claims description 2
- 108090001012 Transforming Growth Factor beta Proteins 0.000 claims description 2
- ZRKFYGHZFMAOKI-QMGMOQQFSA-N tgfbeta Chemical compound C([C@H](NC(=O)[C@H](C(C)C)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CCSC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](C)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N1[C@@H](CCC1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(O)=O)C1=CC=C(O)C=C1 ZRKFYGHZFMAOKI-QMGMOQQFSA-N 0.000 claims description 2
- 230000008468 bone growth Effects 0.000 description 9
- 239000007788 liquid Substances 0.000 description 5
- 238000010586 diagram Methods 0.000 description 4
- 239000000499 gel Substances 0.000 description 4
- 230000008569 process Effects 0.000 description 4
- 238000012360 testing method Methods 0.000 description 4
- 102000007350 Bone Morphogenetic Proteins Human genes 0.000 description 3
- 108010007726 Bone Morphogenetic Proteins Proteins 0.000 description 3
- 229940112869 bone morphogenetic protein Drugs 0.000 description 3
- 238000011161 development Methods 0.000 description 3
- 230000018109 developmental process Effects 0.000 description 3
- 239000012530 fluid Substances 0.000 description 3
- 230000003993 interaction Effects 0.000 description 3
- 239000013543 active substance Substances 0.000 description 2
- 230000037182 bone density Effects 0.000 description 2
- 210000004268 dentin Anatomy 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 238000010883 osseointegration Methods 0.000 description 2
- 238000001356 surgical procedure Methods 0.000 description 2
- 102000008186 Collagen Human genes 0.000 description 1
- 108010035532 Collagen Proteins 0.000 description 1
- 102000003839 Human Proteins Human genes 0.000 description 1
- 108090000144 Human Proteins Proteins 0.000 description 1
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 238000004873 anchoring Methods 0.000 description 1
- 239000013060 biological fluid Substances 0.000 description 1
- 229940088623 biologically active substance Drugs 0.000 description 1
- 230000008614 cellular interaction Effects 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 229920001436 collagen Polymers 0.000 description 1
- 239000004053 dental implant Substances 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 238000005538 encapsulation Methods 0.000 description 1
- 238000010353 genetic engineering Methods 0.000 description 1
- 229910052588 hydroxylapatite Inorganic materials 0.000 description 1
- 238000002513 implantation Methods 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 230000004001 molecular interaction Effects 0.000 description 1
- XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 229910052719 titanium Inorganic materials 0.000 description 1
- 239000010936 titanium Substances 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
- A61C8/00—Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
- A61L27/24—Collagen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/28—Bones
- A61F2/2803—Bones for mandibular reconstruction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/28—Bones
- A61F2002/2817—Bone stimulation by chemical reactions or by osteogenic or biological products for enhancing ossification, e.g. by bone morphogenetic or morphogenic proteins [BMP] or by transforming growth factors [TGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/28—Bones
- A61F2/2875—Skull or cranium
- A61F2002/2889—Maxillary, premaxillary or molar implants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
- A61F2002/30003—Material related properties of the prosthesis or of a coating on the prosthesis
- A61F2002/3006—Properties of materials and coating materials
- A61F2002/30062—(bio)absorbable, biodegradable, bioerodable, (bio)resorbable, resorptive
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2210/0004—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof bioabsorbable
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
- A61F2310/00005—The prosthesis being constructed from a particular material
- A61F2310/00365—Proteins; Polypeptides; Degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/412—Tissue-regenerating or healing or proliferative agents
- A61L2300/414—Growth factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/602—Type of release, e.g. controlled, sustained, slow
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Transplantation (AREA)
- Biophysics (AREA)
- Dentistry (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Prostheses (AREA)
- Materials For Medical Uses (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9901972A SE514342C2 (sv) | 1999-05-31 | 1999-05-31 | Metod, anordning och användning vid implantat för att tillförsäkra tillförsel av bioaktiv substans till implantatets omgivande ben och/eller vävnad |
| SE9901972-1 | 1999-05-31 | ||
| PCT/SE2000/001029 WO2000072778A1 (en) | 1999-05-31 | 2000-05-23 | Method, arrangement and use of an implant for ensuring delivery of bioactive substance to the bone and/or tissue surrounding the implant |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2003500161A true JP2003500161A (ja) | 2003-01-07 |
| JP2003500161A5 JP2003500161A5 (https=) | 2007-07-12 |
Family
ID=20415800
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000620892A Pending JP2003500161A (ja) | 1999-05-31 | 2000-05-23 | インプラントの周囲の骨および／または組織への生物活性物質の送出しを確実にするためのインプラントの方法、構成、および使用 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6918766B1 (https=) |
| EP (1) | EP1207802B1 (https=) |
| JP (1) | JP2003500161A (https=) |
| AT (1) | ATE345746T1 (https=) |
| AU (1) | AU779806B2 (https=) |
| CA (1) | CA2373703C (https=) |
| DE (1) | DE60031991T2 (https=) |
| ES (1) | ES2274791T3 (https=) |
| SE (1) | SE514342C2 (https=) |
| WO (1) | WO2000072778A1 (https=) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060078847A1 (en) * | 2000-09-29 | 2006-04-13 | Kwan Norman H | Dental implant system and additional methods of attachment |
| SE519564C2 (sv) * | 2001-07-04 | 2003-03-11 | Nobel Biocare Ab | Implantat, t ex dentalt implantat, belagt med bentillväxtstimulerande medel |
| SE520756C2 (sv) | 2001-12-21 | 2003-08-19 | Nobel Biocare Ab | Förfarande för att åstadkomma ytstruktur på implantat samt sådant implantat |
| US7615070B2 (en) * | 2002-10-11 | 2009-11-10 | Spineco, Inc. | Electro-stimulation and medical delivery device |
| SE526745C2 (sv) * | 2003-04-17 | 2005-11-01 | Nobel Biocare Ab | Fixtur för förankring i käkben |
| US8372419B2 (en) | 2004-03-10 | 2013-02-12 | Scil Technology Gmbh | Coated implants, their manufacturing and use thereof |
| US7510397B2 (en) * | 2004-10-15 | 2009-03-31 | Hochman Mark N | Method and apparatus for performing maxillary sinus elevation |
| AU2005302484A1 (en) * | 2004-10-28 | 2006-05-11 | Microchips, Inc. | Orthopedic and dental implant devices providing controlled drug delivery |
| WO2007001624A2 (en) * | 2005-06-28 | 2007-01-04 | Microchips, Inc. | Medical and dental implant devices for controlled drug delivery |
| WO2007047556A2 (en) * | 2005-10-14 | 2007-04-26 | Microchips, Inc. | Passive wear-indicating sensor for implantable prosthetic device |
| US8551124B2 (en) * | 2007-04-20 | 2013-10-08 | Stryker Trauma Gmbh | Implantation pin, fixation device and method for implanting the implantation pin |
| ES2304117B1 (es) * | 2008-01-25 | 2009-08-24 | Marcela Ridao Dalmau | Dispositivo para la conformacion de la cavidad sinusal maxilar. |
| KR100944217B1 (ko) * | 2008-02-29 | 2010-02-24 | (주)트리플씨메디칼 | 임플란트의 픽스츄어 |
| US20090298015A1 (en) * | 2008-05-28 | 2009-12-03 | Global Implant Solutions, Llc | Digital Abutment For Dental Implant System |
| US9095396B2 (en) * | 2008-07-02 | 2015-08-04 | Zimmer Dental, Inc. | Porous implant with non-porous threads |
| EP2143451A1 (en) | 2008-07-11 | 2010-01-13 | Nobel Biocare Services AG | Bone implant application |
| US20100015571A1 (en) * | 2008-07-15 | 2010-01-21 | Global Implant Solutions, Llc | Flexible Abutment For Use With A Dental Implant |
| KR100931645B1 (ko) | 2008-09-25 | 2009-12-14 | 주식회사 바이오머테리얼즈코리아 | 치열 교정용 스크류 |
| ES2484465T3 (es) * | 2008-10-10 | 2014-08-11 | Stryker Trauma Gmbh | Kit de perno de implante y método para implantar un perno de implante |
| DE102008055551B4 (de) * | 2008-12-19 | 2018-01-11 | Roman Zolow | Implantat |
| GB2523827A (en) | 2014-03-07 | 2015-09-09 | Nobel Biocare Services Ag | Dental implant |
| GB2523828A (en) | 2014-03-07 | 2015-09-09 | Nobel Biocare Services Ag | Dental implant |
| WO2016172026A1 (en) | 2015-04-20 | 2016-10-27 | The Board Of Regents Of The University Of Texas System | Clec11a is a bone growth agent |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4175326A (en) * | 1977-10-26 | 1979-11-27 | Forsyth Dental Infirmary For Children | Hollow-fiber devices for and a method of the treament and diagnosis of oral diseases |
| US4685883A (en) * | 1983-09-12 | 1987-08-11 | Jernberg Gary R | Local delivery of chemotherapeutic agents for the treatment of periodontal disease |
| US4764377A (en) * | 1983-10-07 | 1988-08-16 | The Forsyth Dental Infirmary For Children | Intra-pocket drug delivery devices for treatment of periodontal diseases |
| DE3601787A1 (de) * | 1986-01-22 | 1987-07-23 | Cox Kirsten | Verfahren zum applizieren von wirkstoffen und dafuer geeigneten applikator |
| US4744755A (en) * | 1986-08-13 | 1988-05-17 | Ross Systems Corporation | Dental implant and method for installing same |
| US4994273A (en) * | 1987-11-02 | 1991-02-19 | Merck & Co., Inc. | Solubility modulated drug delivery device |
| US5700479A (en) * | 1988-12-23 | 1997-12-23 | Guidor Ab | Surgical element and method for selective tissue regeneration |
| US5059123A (en) * | 1990-05-14 | 1991-10-22 | Jernberg Gary R | Periodontal barrier and method for aiding periodontal tissue regeneration |
| WO1992017209A1 (fr) * | 1991-04-08 | 1992-10-15 | Sumitomo Pharmaceuticals Company, Limited | Preparation solide poreuse contenant une substance proteique physiologiquement active |
| US5458884A (en) * | 1992-09-10 | 1995-10-17 | Britton; Peter | Bioerodible device for administering active ingredients |
| US5503558A (en) * | 1993-11-12 | 1996-04-02 | Mcgill University | Osseointegration promoting implant composition, implant assembly and method therefor |
| US5863201A (en) * | 1994-11-30 | 1999-01-26 | Implant Innovations, Inc. | Infection-blocking dental implant |
| US5702449A (en) * | 1995-06-07 | 1997-12-30 | Danek Medical, Inc. | Reinforced porous spinal implants |
| US6132214A (en) * | 1995-12-18 | 2000-10-17 | Jouko Suhonen | Medical implant |
| US6530896B1 (en) * | 1996-05-13 | 2003-03-11 | James B. Elliott | Apparatus and method for introducing an implant |
| KR20000052723A (ko) * | 1996-10-24 | 2000-08-25 | 에스디지아이 홀딩스 인코포레이티드 | 세라믹 융합 임플런트 및 골유도성 인자를 함유하는 조성물 |
| US6413089B1 (en) * | 1999-02-10 | 2002-07-02 | Arthur Ashman | Immediate post-extraction implant |
| IT1307829B1 (it) * | 1999-12-21 | 2001-11-19 | Consiglio Nazionale Ricerche | Protesi dentale con mezzi per il rilascio di farmaci o fattorispecifici atti ad impedire l'insorgenza di infezioni e/o promuovere |
| IL142933A0 (en) * | 2001-05-03 | 2002-04-21 | Dentis Technology Ltd | Polymeric dental implant and method for use thereof |
| US7008226B2 (en) * | 2002-08-23 | 2006-03-07 | Woodwelding Ag | Implant, in particular a dental implant |
-
1999
- 1999-05-31 SE SE9901972A patent/SE514342C2/sv not_active IP Right Cessation
-
2000
- 2000-05-23 CA CA2373703A patent/CA2373703C/en not_active Expired - Fee Related
- 2000-05-23 US US09/980,009 patent/US6918766B1/en not_active Expired - Lifetime
- 2000-05-23 ES ES00937438T patent/ES2274791T3/es not_active Expired - Lifetime
- 2000-05-23 EP EP00937438A patent/EP1207802B1/en not_active Expired - Lifetime
- 2000-05-23 AT AT00937438T patent/ATE345746T1/de not_active IP Right Cessation
- 2000-05-23 AU AU52611/00A patent/AU779806B2/en not_active Ceased
- 2000-05-23 WO PCT/SE2000/001029 patent/WO2000072778A1/en not_active Ceased
- 2000-05-23 DE DE60031991T patent/DE60031991T2/de not_active Expired - Lifetime
- 2000-05-23 JP JP2000620892A patent/JP2003500161A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| ES2274791T3 (es) | 2007-06-01 |
| DE60031991D1 (de) | 2007-01-04 |
| SE514342C2 (sv) | 2001-02-12 |
| DE60031991T2 (de) | 2007-12-20 |
| CA2373703C (en) | 2010-06-22 |
| EP1207802B1 (en) | 2006-11-22 |
| CA2373703A1 (en) | 2000-12-07 |
| ATE345746T1 (de) | 2006-12-15 |
| US6918766B1 (en) | 2005-07-19 |
| WO2000072778A1 (en) | 2000-12-07 |
| SE9901972L (sv) | 2000-12-01 |
| EP1207802A1 (en) | 2002-05-29 |
| SE9901972D0 (sv) | 1999-05-31 |
| AU779806B2 (en) | 2005-02-10 |
| AU5261100A (en) | 2000-12-18 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2003500161A (ja) | インプラントの周囲の骨および／または組織への生物活性物質の送出しを確実にするためのインプラントの方法、構成、および使用 | |
| US11957388B2 (en) | Deformable body and combination of such deformable body and a surgical screw element | |
| US5700479A (en) | Surgical element and method for selective tissue regeneration | |
| Lovschall et al. | Pulp-capping with recombinant human insulin-like growth factor I (rhIGF-I) in rat molars | |
| EP1852135B1 (en) | Medical material, artificial tooth root and method of producing material for clinical use | |
| JP6764966B2 (ja) | 骨インプラントの固定法 | |
| KR101121146B1 (ko) | 임플란트 고정방법, 임플란트용 고정부재 및 임플란트복합재 | |
| US8167618B2 (en) | Arrangement for using osteoinductive or bioactive material to induce bone and/or increase the stability of implants in the jaw bone, and an implant intended for this purpose | |
| EP2108333A1 (de) | Implantat zur Implantation in Knochengewebe oder in durch Knochenersatzmaterial ergänztem Knochengewebe | |
| CA2353524A1 (en) | Methods and articles for regenerating living tissue | |
| CA2682298A1 (en) | Implant for fracture treatment | |
| US4880006A (en) | Bone ingrowth chamber | |
| ES2971693T3 (es) | Implante dental intraóseo bioactivo | |
| JP2003517874A (ja) | 活性物質を放出する手段を備えた歯科補綴構造体 | |
| JP2007500585A (ja) | 構造的／生物学的インプラントシステム | |
| US20070162024A1 (en) | Implant for anchoring in bones | |
| RU117086U1 (ru) | Дентальный имплантат с возможностью внутрикостного введения лекарственных средств для купирования воспаления и усиления процесса остеоинтеграции при дентальной имплантации | |
| RU2137441C1 (ru) | Материал для пластики тканей | |
| CN109152643A (zh) | 模块化垫片装置 | |
| JP2021098013A (ja) | 多孔質内植材料を用いた歯科インプラント | |
| RU2178277C2 (ru) | Материал для остеопластики | |
| PL238183B1 (pl) | Aplikator czynnika aktywnego do implantu stomatologicznego | |
| CA2492699A1 (en) | Arrangement for using bioactive or osteoinductive material to build up a bone-based lateral support for implants in the jaw bone |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20070522 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20070522 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20080502 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20080731 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20080829 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20081126 |
|
| A02 | Decision of refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A02 Effective date: 20090130 |