JP2003304812A - Beverage feeder having function to remove purine alkaloid - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To safely remove purine alkaloids from coffee or tea containing purine alkaloids (caffeine, theophylline, therobromine and the like) in high selectivity at a low cost. <P>SOLUTION: A beverage feeder having an absorption column filled with an absorber ( a molecule inprint polymer, active carbon or the like) for removing purine alkaloids and removing the purine alkaloids by passing a purine alkaloid-containing solution through the column is provided. <P>COPYRIGHT: (C)2004,JPO

Description

Detailed Description of the Invention

[0001]

TECHNICAL FIELD The present invention relates to a coffee maker or tea dispenser having a function of safely and highly selectively depurinating alkaloids from a liquid containing purine alkaloids (caffeine, theophylline, theobromine, etc.), Alternatively, the present invention relates to a beverage supply device such as a device having both functions of a coffee maker and a tea supply device.

[0002]

2. Description of the Related Art Conventionally, coffee, cacao, green tea, black tea, oolong tea, mate tea, cola, guarana, etc. have been extracted and contained purine alkaloids represented by caffeine.
It is a suspended beverage. Such a beverage tends to be unable to sleep at night or cause frequent urination due to its pharmacological action, that is, central nervous system excitatory action and diuretic action.

On the other hand, in order to reach an aging society,
Even if you drink coffee or tea, you are required to be able to sleep at night or not have frequent urination. Also, people with peptic gastric ulcers and those taking theophylline preparations should refrain from drinking coffee or tea due to the pharmacological effects of caffeine. In addition, pregnant women also need to refrain from drinking large amounts of caffeine because it passes through the placenta and may affect the fetus. Therefore, a method of decaffeination from coffee or tea has been reported so that these people can also drink coffee or tea.

First, as an extraction method, a method of extracting caffeine with water (JP-A-52-134054) and a method of extracting caffeine with an organic solvent (JP-A-46-6925) are disclosed. JP-A-60-156596), a method of extracting with a supercritical fluid (Japanese Patent Laid-Open No. 46-
1820, JP-A-55-69585, JP-A-02-20249). As the crystallization method, a method of separating the crystals of the caffeine / caffeic acid complex by adding caffeic acid (JP-A-61-1877).
48, JP-A-02-27945).
Further, as a membrane separation method, there is a method of treating with a reverse osmosis membrane or an ultrafiltration membrane (JP-A-52-139756),
As the inclusion method, there is a method of inclusion with a β-cyclodextrin polymer (JP-A-07-16057). In addition, as a biomethod, a method of treating with an enzyme (Japanese Patent Laid-Open No. 52-143272) and a method of inhibiting caffeine production by a genetic recombination method (Tokuhyohei 2001-2001)
No. 5,196,49).

On the other hand, as the adsorption method, a method using a synthetic resin (Japanese Patent Laid-Open No. 51-91368, Japanese Patent Laid-Open No. 57-
No. 93980), a method using a zeolite and a molecular sieve (JP-A-55-88806, JP-A-05-153910), and a method using solid fiber particles derived from a plant rich in lignin (JP-A-SHO). 54-26
364), a method using activated carbon (JP-A-55-55).
29995 and JP-A-57-12952). Among the methods of using activated carbon, a method of using activated carbon in a coffee maker or tea dispenser for personal or business use, not in the manufacturing process of a factory (JP-A-01-313020 and JP-A-06-315434). , A method of enclosing activated carbon in a tea bag (Japanese Patent Laid-Open No. 01-148150) has been reported. On the other hand, as an adsorption method applied to a coffee maker or a tea dispenser, a method in which a column is filled with an adsorbent to pass coffee or tea is disclosed in JP-A-
No. 313018 and Japanese Patent Application Laid-Open No. 05-111437, these are not for the purpose of decaffeination but for the purpose of preventing the taste from changing during long-term storage. Further, there is also a method of installing an adsorbent-filled column for the purpose of purifying residual chlorine and organic substances of water for making coffee or tea (Japanese Patent Laid-Open No. 01-212115).

As described above, although there is a method of decaffeination from coffee or tea, in actuality, in order to produce a decaffeinated product, the initial investment is large and the cost is high.
There are still few commercial products because of safety issues due to the use of organic solvents and selectivity issues such as the removal of taste and aroma components other than caffeine.

On the other hand, as an adsorption method, there is an example in which a caffeine imprinted polymer is used as an adsorbent. However, this is a method of encapsulating the adsorbent caffeine imprinted polymer in a porous bag (US Pat. No. 6,322,834).
And the decaffeination efficiency is not good. Further, a method of packing the column (European Patent Application Publication No. 0776607).
No.), but it is limited to decaffeination from coffee, and the concentration of caffeine is low, so the adsorption capacity of the column is small and the throughput is low. In addition, reuse of the filler by cleaning and heat retention are not considered. Furthermore, in both cases, the template is caffeine only, and the object to be removed is limited to caffeine, and other purine alkaloids having similar structures, namely theophylline, theobromine, etc. I can't find it.

[0008]

[Problems to be Solved by the Invention] Purine alkaloid-containing beverages such as coffee or teas can be safely and highly selectively depurinated alkaloids at a low cost with a beverage feeder such as a personal or commercial coffee maker or tea dispenser. It is desirable to be able to do so, and it is required that it can be easily drunk by an individual, a restaurant / dining room, or a vending machine, but the above-mentioned conventional techniques do not sufficiently meet such a demand.

[0009] That is, an object of the present invention is to provide a beverage supplier having a function of depurinating alkaloids containing purine alkaloids such as coffee or tea at low cost, safely and highly selectively.

Another object of the present invention is to provide a beverage supplier capable of increasing / regenerating the adsorbent treatment capacity of the beverage supplier and providing hot or cold depurinated alkaloid beverages.

[0011]

As a result of intensive studies, the inventors of the present invention have packed a column with a specific adsorbent for depurination alkaloids in a beverage supply device, and charged this column with a purine alkaloid-containing beverage. It was found that the purine-free alkaloids can be safely produced at low cost by passing the solution through, and the present invention has been completed.

The present inventors have further found that by using caffeine-imprinted adsorbent, depurinating alkaloids can be safely and highly selectively produced at low cost, and the present invention has been completed.

The present inventors have further found that even a purine alkaloid other than caffeine which is molecularly imprinted as an adsorbent can be safely and highly selectively depurinated alkaloid at low cost, and the present invention is completed. Came to.

The present inventors have further increased the adsorption capacity of the adsorbent by diluting the liquid after passing the purine alkaloid-containing aqueous solution adjusted to a higher concentration than that for ordinary drinking through the column. It was found that the amount of depurinated alkaloids to be treated can be greatly increased, and the present invention has been completed.

The present inventors can further prevent clogging of the column and deterioration of the capacity of the adsorbent by filtering the solid content of the purine alkaloid-containing aqueous solution and passing the filtered purine alkaloid-containing aqueous solution through the column. The present invention has been completed and the present invention has been completed.

The present inventors have further found that the adsorption capacity can be regenerated by providing a means for washing the adsorbent, and have completed the present invention.

The present inventors have further found that a depurinized alkaloid beverage can be supplied while being warm or cold by having a means for keeping the adsorbent warm,
The present invention has been completed.

That is, the present invention is a beverage supplier characterized in that a column is filled with an adsorbent for depurine alkaloids, and the purine alkaloid-containing aqueous solution is passed through the column to depurine alkaloids. .

[0019]

BEST MODE FOR CARRYING OUT THE INVENTION In the present invention, examples of the adsorbent packed in the column include ion exchange resins, synthetic resins such as synthetic adsorbents, zeolites such as molecular sieves,
Examples include hydrophobic porous substances such as activated carbon, and in particular, polymers in which caffeine or a purine alkaloid similar to caffeine is molecularly imprinted (MIP: Molecularly
Imprinted Polymer).

The shape of the adsorbent may be appropriately determined as necessary, but it is preferably spherical for uniform packing and uniform liquid flow into the column. The particle size of the adsorbent may be determined according to various conditions such as the size of the column. In general,
When used in coffee makers or tea makers for personal and commercial use, the particle size of the adsorbent is preferably 1 to 1000 μm,
50-500 micrometers is more preferable. The lower limit value of each of the above ranges is significant in terms of pressure loss and the like, and the upper limit value is significant in terms of downsizing of the column.

The shape and material of the column may be appropriately determined as needed. When a heat-retaining means such as a heater or a cooler is provided, the material of the column has a high thermal conductivity, for example, a metal or alloy such as stainless steel is preferable, and when the heat-retaining function is unnecessary, a material having a low heat conductivity, For example glass,
A plastic such as polycarbonate having a heat distortion temperature of 100 ° C. or higher is preferable.

The use of a molecular imprinted polymer (MIP) as the adsorbent is particularly preferable in that the depurination alkaloid can be safely and highly selectively removed at low cost.

Caffeine or a caffeine-like purine alkaloid is used as a template for the molecularly imprinted polymer. Purine alkaloids similar to caffeine are, for example, theophylline, theobromine and the like.

The method for producing the molecular imprint polymer is
There is no particular limitation. For example, after template-polymerizing a monomer using the above-mentioned purine alkaloid as a template,
Alternatively, a method may be mentioned in which the template is dispersed in a dissolved or melted polymer, the solvent is removed or the polymer is solidified by cooling, and then the template is removed.

As a method of template polymerization, for example, a complex of a template and a functional monomer is formed by a covalent bond, and a crosslinkable monomer is mixed with the complex and polymerized,
A covalent bond type (G. Wulff, A. Sharhan, Angew. C that removes the template from the obtained polymer by hydrolysis, etc.)
hem., 84 , 364 (1972)), and also, for example,
A complex of template and functional monomer is formed by non-covalent bond such as ionic bond and hydrogen bond, cross-linkable monomer is mixed with this complex and polymerized, and the template is removed from the obtained polymer by extraction, evaporation, etc. Non-covalent bond type (LI, Andersson, B. Sellergren, K. Mosbach, Tet
rahedron Lett., 25 , 5211-5214 (1984)) is known.

Further, in situ molecular imprinting method (F. F.), in which a porous MIP is directly prepared in a column simply by heating a column containing a template, a functional monomer, a crosslinkable monomer, a polymerization initiator and a solvent. Svec, JM Frec
het, J. Anal. Chem., 64, 820-822 (1992), J. Matsui,
T. Kato, T. Takeuchi, K. Yokoyama, M. Suzuki, E. Ta
miya, I. Karube, Anal. Chem., 65, 2223 (1993)).

On the other hand, as a method of molecular imprinting without passing through a polymerization process, for example, a template is dispersed in a dissolved or melted polymer, and the functional group of the polymer is covalently or non-covalently bonded to solidify the template. Simple molecular imprint method for removal (HY Wang, Langmuir,
Vol.13, No.20, 5396-5400 (1997), Yoshikawa M: “Mol
ecular and Ionic Recognition with Inprinted Polyme
rs (ACS Symposium Series 703) ", Bartsch RA, Maeda
Med., Chap.12, ACS, Washington DC (1998)) are known.

The adsorbent produced by the molecular imprinting method may be synthetic resin such as ion exchange resin or synthetic adsorbent, zeolite such as molecular sieve, or hydrophobic porous substance such as activated carbon, which may be organic or inorganic. It may be a mixture (hybrid system) of. As an inorganic adsorbent,
For example, silica, alumina, magnesia, titanium oxide,
Silicate, diatomaceous earth, aluminosilicate, layered compound,
Examples thereof include zeolite, activated carbon, graphite and the like. An adsorbent in which a complex of a template and a functional monomer is a covalent bond is obtained, for example, by forming a complex by a covalent bond of a coupling agent and a template and performing dehydration condensation with a silane monomer, water glass, alumina sol, etc. . Non-covalently bound adsorbents include, for example, coupling agents,
It can be obtained by adding a template to silane monomer, water glass, alumina sol or the like, forming a complex by a non-covalent bond, and performing dehydration condensation. Further, the composite and the inorganic monomer may be coated on an inorganic carrier and then dehydrated and condensed. Further, a treatment for making the surface hydrophobic may be applied.

In the case of an organic adsorbent, examples of the functional monomer forming a complex with the template include unsaturated carboxylic acid, (meth) acrylic acid ester, (meth) acrylamide derivative, styrene derivative, vinyl ester and allyl. Alcohol derivatives and other vinyl compounds can be used. In addition, "(meth) acrylic" is a general term for acrylic and methacrylic. Examples of the crosslinkable monomer to be mixed with the functional monomer include aliphatic or aromatic polyvinyl monomers such as ethylene glycol dimethyl acrylate, N, N'-methylenebisacrylamide and divinylbenzene. When the complex of the template and the functional monomer is a covalent bond type, a monomer that is not easily decomposed when removing the template is preferable, and divinylbenzene is particularly preferable.

The hybrid adsorbent is produced by forming an organic MIP on the surface of the above-mentioned inorganic adsorbent.
The inorganic carrier and the organic MIP may be bonded by physical coating or may be chemically bonded by using a coupling agent.

The molar ratio of the functional monomer to the crosslinkable monomer is preferably 0.5 to 10 as the crosslinkable monomer / functional monomer, more preferably 2 to 5. The molar ratio of monomer to template is monomer / template = 5 to 100
Is preferable, and 10-80 is more preferable.

The functional monomer and the template may be covalently bonded by esterification, etherification or amidation using an acid or alkali such as hydrochloric acid, sulfuric acid, phosphoric acid or p-toluenesulfonic acid.

When the molecular imprint polymer is produced by polymerization, the polymerization solvent may be any solvent which is inert in the system. For example, chloroform, toluene, acetone, acetonitrile, tetrahydrofuran, organic solvents such as various alcohols, or water can be used. As the polymerization initiator, for example, a peroxide such as ammonium persulfate or an azo polymerization initiator such as azobisisobutyronitrile can be used. Further, ultraviolet rays can be used together for the purpose of polymerization. The polymerization temperature may be any temperature that does not exceed the boiling point of the solvent, but is preferably room temperature to 60 ° C.
The polymerization time is preferably 1 to 24 hours, more preferably 3 to 12 hours.

On the other hand, in the case of production by the simple molecular imprinting method, as the polymer, for example, polyethylene,
Polypropylene, polyvinyl chloride, polyvinyl alcohol, polyester, polystyrene, polyacrylonitrile, polyacrylamide, nylon, cellulose, cellulose ester, and polymers and copolymers of the above-mentioned functional monomers can be used. The polymer may be dissolved in a solvent or melted in carrying out the simple molecular imprint method. In the simple molecular imprint method, for example, the polymer is dissolved or melted in a solvent, and the template is dispersed and solidified by evaporation or cooling of the solvent while covalently or noncovalently bonded to the functional group of the monomer.

The obtained polymer may be pulverized, or a dispersion stabilizer such as polyvinyl alcohol may be added to obtain a spherical polymer by suspension polymerization or emulsion polymerization. However, the shape of the obtained polymer does not necessarily have to be a particle shape, and the porous MIP may be directly prepared in the column by an in situ molecular imprinting method.

As a method for removing the template from the polymer obtained as described above, for example, a method using a Soxhlet extractor, a method of extracting by filling a column and passing through, a method of batch stirring extraction, heating Alternatively, there is a method of removing the template by evaporation under reduced pressure. As the extraction solvent, in the case of a covalent bond type, an aqueous solution containing an acid or an alkali can be used, and in the case of a non-covalent bond type, a good solvent for the template, such as water or alcohol, can be used. You may add an organic acid to this.

The purine alkaloid can be removed by filling the column with such a packing material and passing the purine alkaloid-containing aqueous solution through the column. The purine alkaloid-containing aqueous solution is, for example, a liquid extract of coffee or tea, or a liquid obtained by dissolving or suspending instant coffee or powdered tea. The purine alkaloid-containing aqueous solution to be passed through the column may have a concentration at the time of normal drinking. However, first, a liquid having a concentration higher than that for normal drinking is prepared by extraction, dissolution, or suspension, and this high-concentration liquid is passed through a column for depurination alkaloids, and then water ( It is preferable to dilute it with hot water etc.) and return to a normal concentration before drinking. In this case, the adsorption capacity of the adsorbent can be increased, and the throughput can be increased substantially until breakthrough. A liquid having a concentration higher than that for normal drinking can be prepared, for example, by reducing the amount of water used for extraction, dissolution or suspension.
In this case, the amount of water used is preferably 95 to 1% by mass, and more preferably 60 to 5% by mass of the amount of water for drinking as it is. Further, in this case, it is preferable to provide the beverage supplier with means for diluting the liquid after passing through the column with water. In addition, although the case where water is used has been described in the above example, in addition to water, for example, sugar water or an aqueous alcohol solution may be used.

The temperature at which the purine alkaloid-containing aqueous solution is passed through the column may be between the melting point and the boiling point of the aqueous solution, and is preferably 1 to 95 ° C.

In order to prevent clogging of the column, it is preferable to filter the solid content of the purine alkaloid-containing aqueous solution and then pass the solution through the column. The filter for filtering the solid content is not particularly limited. For example, the aperture is 0.1μ
Filter papers, filter cloths, membranes, hollow fiber filters and the like having a size of m or more can be used. It is preferable to provide the beverage supplier with means for filtering the solid content of the purine alkaloid-containing aqueous solution.

The column packed with the adsorbent is preferably washed as needed, and such a washing means is preferably provided in the beverage feeder of the present invention. Even after the adsorbent has passed through once, it can be repeatedly used well if it is washed. This washing can be performed, for example, by passing water or hot water through the column using a pump or the like. Regarding the time interval of washing, it is preferable to calculate the adsorption capacity of the adsorbent in advance and automatically wash at equal intervals before breakthrough. The liquid may be manually washed. Alternatively, a tank containing a cleaning solution such as acetic acid water or an acetic acid / ethanol solution may be separately prepared for the passage cleaning. In this case, after washing, replacement washing with water or boiling water is necessary so that the washing liquid does not remain in the column. The amount of cleaning liquid is not particularly limited. The amount of liquid for replacement cleaning is
From the viewpoint of the cleaning effect, the larger the amount, the better, but the amount is usually 1 to 50 times the column volume. Further, the cleaning liquid may be allowed to flow backward to prevent clogging.

When it is necessary to keep the temperature of the adsorbent, it is preferable to appropriately provide heat retaining means. For example, the column itself may be used as a heating element or a cooling element, an electric heater or a cooler may be wound around the column to heat or cool it, or the column may be made into a double tube to pass a heat medium or a refrigerant to the outside. . As a result, the temperature of the purine alkaloid-containing beverage passed through the column can be controlled, and a hot or cold beverage can be supplied.

In the beverage feeder of the present invention, the coffee maker may be of any type such as drip type, siphon type, espresso type. Further, it may be a simple one that only sucks the coffee liquid with a pump and passes it through the adsorbent-filled column. The tea dispenser of the present invention is also the same, and may be a simple one that only sucks the tea leaf extraction / suspension and passes it through the adsorbent-filled column. Further, a device having both functions of a coffee maker and a tea supply device may be used.

[0043]

EXAMPLES Examples of the present invention will be described below.
The present invention is not limited to these examples.

The purine alkaloid adsorption property of the adsorbent was expressed by the following Freundlich adsorption equilibrium equation. Freundlich adsorption equilibrium equation: q = k × C ^{1 / n} q: Adsorption amount [kg / kg] C: Purine alkaloid concentration [kg / m ³ ] k, n: Freundlich constant.

In the examples, the purine alkaloids were quantitatively analyzed under the following HPLC conditions. HPLC: High performance liquid chromatography column manufactured by JASCO Corporation: ODS-2 (ID 4.6 mmφ × 250 mm) manufactured by GL Sciences Inc. Column temperature: Room temperature eluent: Acetonitrile / H ₂ O = 1/9 Flow rate: 0.0. 8 ml / min detection: UV254 nm injection: 1 μl.

<Example 1 (decaffeination by a column packed with activated carbon)> The adsorption characteristics of caffeine in an aqueous solution of activated carbon having a particle size of 150 to 250 μm are Freundlich adsorption equilibrium equation, k = 0.158, n = 1. It was 43. 16 g of this activated carbon is applied to a column with an inner diameter of 20 mm and a length of 100 mm.
When it was filled and the coffee containing 300 ppm of coffee caffeine was passed through, it was almost completely decaffeinated. In addition, since 2600 ml of liquid was passed through and breakthrough, 1 L of hot water was passed and washed, and reuse was possible.

<Example 2 (decaffeination using a column packed with a caffeine-imprinted polymer)> Chloroform 1
To 68.0 g, methacrylic acid (MA
A) 10.60 g, ethylene glycol dimethacrylate (EDMA) 73.60 g as a cross-linking monomer, caffeine 2.00 g as a template, and azobisisobutyronitrile (AIBN) 0.8 g as an azo polymerization initiator are added. To dissolve it, blow nitrogen for 5 minutes to deoxygenate, UV lamp manufactured by Riko Kagaku Sangyo Co., Ltd., trade name UVL-100P
Polymerization was carried out by irradiating at room temperature for 3 hours using a (wavelength 312 to 577 nm, max 365 nm) to obtain a polymer. This polymer was crushed in a mortar and a sieve was used to obtain a fraction having a polymer particle size of 150 to 250 μm. 200 g of this fraction was added to acetic acid: methanol = 1: 9
The template is removed by stirring and washing with 1,200 ml of (v / v) mixed solution, and 1,200 m of pure water is added.
Stirring and washing with l were performed three times to obtain a caffeine imprinted polymer.

The caffeine adsorption characteristics of this caffeine imprinted polymer in an aqueous solution are k = 0.018 and n = 1.15 in the Freundlich adsorption equilibrium equation, and theophylline adsorption characteristics are k = 0.015 and n. = 1.11, which adsorbs caffeine and then selectively theophylline.

This caffeine imprint polymer 20
0 g was packed in a column with an inner diameter of 50 mmφ and a length of 200 mm, and caffeine was added at 300 ppm and theophylline was added at 3 ppm.
When green tea containing ppm was passed through, decaffeination / theophylline was almost completely removed. Also 3,700m
Since it broke through after passing 1 l, it was reused when 1 L of hot water was passed and washed.

<Example 3 (decaffeination by a column packed with a caffeine imprinted polymer)> First, commercially available regular coffee was extracted with hot water in an amount of 1/10 of the amount that is normally drunk, and 3,000 ppm of caffeine was contained. A high concentration of coffee was obtained. When this high-concentration coffee was passed through the same caffeine-imprinted polymer-packed column as in Example 2, it was possible to almost completely decaffeine. In addition, since 2700 ml of liquid was passed through and breakthrough, 1 L of hot water was passed and washed, and then reuse became possible.

When this decaffeinated high-concentration coffee was diluted 10 times with boiling water, it became a flavor for ordinary drinking. In this example, the decaffeinated coffee obtained by breakthrough was 27 L after dilution. That is, as compared with Example 2, it was possible to substantially increase the throughput until breakthrough.

<Example 4 (decaffeination by a column filled with theophylline imprinted polymer)> A molecular imprinted polymer was prepared in the same manner as in Example 2 except that theophylline was used as a template. The caffeine adsorption property of this theophylline imprinted polymer in an aqueous solution is Freundlich adsorption equilibrium equation, and k =
It was 0.013 and n = 1.13, which adsorbed theophylline and then caffeine selectively.

This theophylline imprinted polymer 2
When 00 g was filled in a stainless steel column having an inner diameter of 50 mmφ and a length of 200 mm, and 90 ° C. coffee containing 300 ppm of caffeine was passed, decaffeination was almost completely completed. Also, since 2,500 ml of liquid was passed through, it broke through.
Reusable. Further, by winding an electric heater around this stainless steel column to keep it warm, it was possible to maintain the temperature at 90 ° C. without any decrease in temperature after passing through the column.

[0054]

As described above, according to the present invention,
It is possible to provide a beverage supplier having a function of depurinating alkaloids selectively and safely from a purine alkaloid-containing liquid at low cost.

Front page continuation (51) Int.Cl. ⁷ Identification code FI theme code (reference) B67D 1/07 A23L 2/00 X 3/00 FF term (reference) 3E082 AA01 BB04 CC03 4B004 AA11 4B017 LC03 LG14 LP07 4B027 FB13 FB24 FC04 FP74 FQ11

Claims (7)

[Claims] 1. A beverage feeder characterized in that a column is filled with an adsorbent for depurinated alkaloids, and the purine alkaloid-containing aqueous solution is passed through the column to depurinate alkaloids. 2. The beverage feeder according to claim 1, wherein the adsorbent is a molecule imprinted with caffeine. 3. The beverage feeder according to claim 1, wherein the adsorbent is a molecular imprint of a purine alkaloid other than caffeine. 4. The beverage according to claim 1, further comprising a means for diluting the liquid after passing the purine alkaloid-containing aqueous solution adjusted to have a higher concentration than that for ordinary drinking through the column. Feeder. 5. A purine alkaloid-containing aqueous solution is provided with a means for filtering the solid content, and the purine alkaloid-containing aqueous solution filtered by the means is passed through the column.
The beverage supply device according to claim 1. 6. A means for washing the adsorbent is provided.
The beverage supply device according to any one of claims 1 to 5. 7. A means for retaining the temperature of the adsorbent is provided.
The beverage supply device according to any one of claims 1 to 6.