JP2003199828A - Syringe - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a syringe capable of discharging liquid in an accurate volume and in an easy operation. <P>SOLUTION: This syringe 1 is equipped with an outer barrel 2, a gasket 3, a plunger 4 and a stopper 5. The gasket 3 is slidingly provided within the outer barrel 2. The plunger 4 moves and operates the gasket 3. The stopper 5 is slidingly provided along the longitudinal direction of the plunger 4. The stopper 5 is fastened to the plunger 4 by meshing the engagement part installed within the stopper 5 with racks 47a, 47b formed in the plunger 4. When an actuation part 71 is pressurized, the stopper 5 is released from its stationary state permitting its position to be adjusted on the plunger 4. When the pressure exerted on the actuation part 71 is released, the stopper 5 returns to its stationary state. When the plunger 4 is pressurized in the leading-end direction, the leading-end surface 66 of the stopper 5 comes into contact with the forward-end part 28 of the outer barrel 2, and the insertion depth of the plunger 4 into the outer barrel 2 is regulated so that medicament 100 is discharged from a reduced-in-diameter part 22 in a pre-determined volume. <P>COPYRIGHT: (C)2003,JPO

Description

Detailed Description of the Invention

[0001]

TECHNICAL FIELD The present invention relates to a syringe.

[0002]

2. Description of the Related Art A syringe has an outer cylinder, a gasket inserted in the outer cylinder, and a pusher (plunger rod) connected to the gasket. The pusher is pressed to operate the gasket. The liquid such as the medicine is discharged by sliding it in the tip direction in the outer cylinder.

At this time, in order to discharge an accurate amount of liquid, it is necessary to adjust the moving amount of the gasket while looking at the scale attached to the outer peripheral surface of the outer cylinder, and the pusher must be operated carefully. I won't.

However, in the conventional syringe, the discharge amount of the liquid is apt to be excessive or insufficient due to an operation error of the pusher (too much push, insufficient push), misreading of the scale, or the like. There was a problem.

[0005]

SUMMARY OF THE INVENTION An object of the present invention is to provide a syringe capable of discharging an accurate amount of liquid with a simple operation.

[0006]

The above objects are achieved by the present invention described in (1) to (14) below.

(1) An outer cylinder, a gasket that can slide in the outer cylinder, a pusher that is inserted through a base end opening of the outer cylinder and moves and operates the gasket, and a length of the pusher. A stopper that is slidable along the direction, a fixing unit that selects and fixes the position of the stopper on the pusher, and an operation unit that is provided on the stopper and that performs a pressing operation, a pulling operation, or a clamping operation. With and
The position of the stopper on the pusher can be adjusted by releasing the fixing of the fixing means by the operation of the operation portion, and the stopper comes into contact with a part of the outer cylinder, A syringe characterized in that the insertion depth of the pusher into the outer cylinder is regulated.

(2) The syringe according to (1), wherein the fixing means is configured to return to a fixed state by elasticity when the operation on the operation portion is released.

(3) The fixing means is provided on the pusher, and has a rack having a plurality of engaging concave portions or engaging convex portions formed at predetermined intervals along the longitudinal direction of the pusher, and the stopper. And an engaging portion that is displaceable between a state in which the rack is engaged with the rack and a state in which the rack is retracted from the rack, and the engaging portion is always engaged with the rack. The syringe according to (1) or (2) above, which is retracted from the rack by the operation described in 1.

(4) The fixing means is interlocked with the operating portion and is displaced between a first position for pressing the engaging portion in a direction to engage with the rack and a second position for releasing the pressing. And a biasing unit that biases the pressing unit to come to the first position, and the fixing unit is configured such that the pressing unit is always at the first position, and The engaging portion is in a state of engaging the rack and fixing the stopper, and when the operating portion is operated, the pressing portion moves to the second position so that the engaging portion moves from the rack. When retracted and this fixation is released, and the operation on the operation portion is released, the urging force of the urging means causes
The syringe according to (3) above, which operates to return to a state where the stopper is fixed.

(5) The fixing means has a biasing means for biasing the engaging portion so as to be displaced from the state of retracting from the rack to the state of being engaged with the rack. The portion is in a state of engaging the rack and fixing the stopper, and when the operating portion is operated, the engaging portion retracts from the rack and the fixation is released.
The syringe according to (3) above, which is operated to return to a state in which the stopper is fixed by the urging force of the urging unit when the operation on the operation unit is released.

(6) The pusher has a main body having a shape in which plate pieces are crossed in a cross shape, and the rack is formed on a part of the plate pieces, (3) to (5). The syringe according to any one of 1.

(7) The syringe according to any one of (3) to (6), wherein the rack is provided in a pair.

(8) The pusher has a rail portion,
The stopper has a sliding portion that slides along the rail portion, and the sliding portion guides on the rail portion to slide along the longitudinal direction of the pusher (1). The syringe according to any one of (1) to (7).

(9) The syringe according to any one of the above (1) to (8), wherein the pusher is provided with a scale indicating the position of the stopper corresponding to the discharged liquid amount.

(10) The syringe according to (9), wherein the pusher has a positioning means for positioning the stopper at a position of 0 on the scale.

(11) The syringe according to any one of (1) to (10), wherein the maximum width of the stopper is smaller than the maximum width of the pusher.

(12) The syringe according to any one of the above (1) to (11), wherein the operation section is pressed by a finger.

(13) The syringe according to any one of the above (1) to (12), wherein the operation section is operated to be held by a finger.

(14) The syringe according to any one of the above (1) to (13), wherein a drug is stored in advance in a space surrounded by the outer cylinder and the gasket.

[0021]

BEST MODE FOR CARRYING OUT THE INVENTION The syringe of the present invention will be described below in detail with reference to the preferred embodiments shown in the accompanying drawings.

<First Embodiment> FIG. 1 is a partial vertical sectional view showing a first embodiment of a syringe of the present invention, and FIG. 2 is a perspective view (disassembled state) of a stopper in the syringe shown in FIG. 2 is a sectional view taken along line XX in FIG. 2, and FIG.
5 is a partial cross-sectional perspective view showing the main body portion and the stopper of the pusher in the syringe shown in FIG. 1, respectively. For convenience of explanation, the left side in FIG. 1 is called the “tip” and the right side is called the “base end”,
The upper side in FIGS. 2 to 6 is referred to as “upper” and the lower side is referred to as “lower”.

A syringe 1 of this embodiment shown in FIG. 1 is a prefilled syringe in which a drug is stored in advance in the syringe, and an outer cylinder (syringe outer cylinder) 2 and a gasket which can slide in the outer cylinder 2. 3, a pusher (plunger rod) 4 for moving the gasket 3, and a stopper 5 slidably installed along the longitudinal direction of the pusher 4. The gasket 3 is connected to the tip of the pusher 4. The configuration of each unit will be described below.

The outer cylinder 2 is composed of a bottomed cylindrical member having a bottom portion 21 on the tip side, and the outer cylinder 2 is provided at the center of the bottom portion 21.
A reduced diameter portion 22 having a reduced diameter is integrally formed with the body portion of the. For example, a hub of a needle tube, connectors and the like (not shown) are fitted and attached to the reduced diameter portion 22 for use.

A male screw (luer lock screw) may be formed on the outer circumference of the base end portion of the reduced diameter portion 22.

At the tip of the reduced diameter portion 22, as a sealing member,
A membrane 24 made of an elastic material is attached to hermetically seal the inner cavity 23 of the reduced diameter portion 22.

The cap 2 is provided outside the reduced diameter portion 22.
9 is fitted and fixed. An opening 291 is formed at the tip of the cap 29, and the opening 291 is formed.
By sandwiching the outer peripheral portion of the membrane 24 between the edge of the membrane and the tip surface of the reduced diameter portion 22, the membrane 24 is fixed in an airtight (liquid-tight) manner.

The reduced diameter portion 22, the film 24, and the cap 29
And may be adhered or fused to each other with an adhesive.

The membrane 24 can be pierced by a needle body such as a double-ended needle. In this case, the form of the film 24 is not limited to the film form as long as it can be pierced by the needle body, and may be a block form (plug body), for example.

As the constituent material of the film 24, for example, the constituent materials of the gasket 3 described later can be used.

The sealing member for sealing the tip of the reduced diameter portion 22 is not limited to the illustrated construction, but may be, for example, a film or the like (not shown).

A plate-shaped flange 25 is integrally formed on the outer periphery of the base end of the outer cylinder 2. Pusher 4 to outer cylinder 2
On the other hand, when performing a relative movement operation, the flange 25 can be operated by placing a finger on it.

The constituent material of the outer cylinder 2 is not particularly limited, but for example, polyvinyl chloride, polyethylene, polypropylene, cyclic polyolefin, polystyrene, poly- (4-methylpentene-1), polycarbonate, acrylic resin, acrylonitrile. -Butadiene-styrene copolymer, polyester such as polyethylene terephthalate, butadiene-styrene copolymer, polyamide (for example, nylon 6, nylon 6.6, nylon 6/10,
Various resins such as nylon 12) can be mentioned, and among them, polypropylene, cyclic polyolefin, polyester, poly- (4-
Resins such as methylpentene-1) are preferred.

The constituent material of the outer cylinder 2 is preferably substantially transparent in order to secure the internal visibility.

A medicine 100 is stored in a liquid-tight manner in a space surrounded by the outer cylinder 2 and the gasket 3. Drug 100
The form may be any form such as solid form (including powder form and granule form) and liquid form. In the present embodiment, a liquid form drug will be representatively described.

Examples of the drug 100 include anticancer agents, anesthetics, stimulants, narcotics, sugar injection solutions such as glucose, electrolyte correction injection solutions such as sodium chloride and potassium lactate, vitamin preparations, vaccines, and antibiotic injections. Liquids, contrast agents, steroids, proteolytic enzyme inhibitors, various chemicals such as fat emulsions, distilled water, disinfectants, liquid foods,
Examples thereof include alcohol.

A scale 27 is formed on the outer peripheral surface of the outer cylinder 2. Thereby, the amount of liquid in the syringe 1 can be grasped. In the illustrated configuration, the scale 27 has 0 to 5
Up to mL is attached.

A gasket 3 made of an elastic material is housed in the outer cylinder 2. On the outer peripheral portion of the gasket 3, a plurality of ring-shaped convex portions 31, 32 and 33 are formed over the entire circumference. The convex portions 31, 32, and 33 slide while closely contacting with the inner peripheral surface 26 of the outer cylinder 2, whereby the liquid tightness can be more reliably maintained and the slidability can be improved.

In this embodiment, two convex portions 31, 32 and 33 are formed along the longitudinal direction of the syringe 1. That is, the convex portions 31, 32, and 33 are formed on the base end portion, the intermediate portion, and the tip end portion of the gasket 3, respectively. Further, the tip surface 36 of the gasket 3 is a tapered surface whose outer diameter gradually decreases toward the tip.

In the present invention, the formation position, the number, the cross-sectional shape, etc. of the convex portions 31, 32 and 33 are not limited to this.

Further, the gasket 3 is formed with a hollow portion 34 which is open at the base end surface thereof. This hollow portion 34
The head portion 43 of the pusher 4 described later is inserted (screwed in). A female screw 341 is formed on the inner surface of the hollow portion 34.

The constituent material of the gasket 3 is not particularly limited, but for example, various rubber materials such as natural rubber, butyl rubber, isoprene rubber, butadiene rubber, styrene-butadiene rubber, silicone rubber, polyurethane type, polyester type, and the like. Examples of the elastic material include various thermoplastic elastomers such as polyamide, olefin, and styrene, or a mixture thereof.

It should be noted that at least the outer peripheral portion of the gasket 3 may be made of the elastic material as described above,
For example, it may have a core portion (not shown) made of a resin material, and the elastic material is arranged so as to cover the outer periphery of the core portion. In this case, the female screw 3
41 will be formed.

A pusher 4 for moving the gasket 3 in the longitudinal direction in the outer cylinder 2 is connected (mounted) to the gasket 3 as described above.

The pusher 4 has a main body 40 having a shape in which plate pieces are crossed in a cross shape, and a flange-shaped finger contact portion 401 is formed at the base end of the main body 40. By pressing the finger rest 401 with a finger or the like, the pusher 4
Move to the tip direction.

On the tip side of the main body 40, there is a first collar-shaped member.
The flange 41 and the second flange 42 located on the base end side of the first flange 41 are integrally formed with the main body 40. The first flange 41 and the second flange 42 are installed substantially parallel to each other with a predetermined interval, for example, an interval of about 3 to 50 mm.

Further, a head portion (connecting portion) 43 which is inserted into the hollow portion 34 of the gasket 3 and is connected to the gasket 3 on the tip side of the first flange 41 of the pusher 4.
Are formed.

On the outer periphery of the head portion 43, a male screw 431 that can be screwed into the female screw 341 on the inner surface of the hollow portion 34 is formed. The male screw 431 and the female screw 341 are screwed together to connect the gasket and the pusher 4.
In such a connected state, the front end surface of the first flange 41 is in contact with or in close contact with the base end surface of the gasket 3.

In the present invention, the connecting structure between the gasket 3 and the pusher 4 may be other than screwing, for example, fixing such as adhesion or fusion, fitting, loose fitting and the like.

The constituent material of the pusher 4 is not particularly limited, and, for example, the same material as the constituent material of the outer cylinder 2 can be used.

In the syringe 1 of the present invention, the stopper (insertion depth regulating member) 5 movably installed along the longitudinal direction of the pusher 4 and the position of the stopper 5 on the pusher 4 are selected. (Adjustment) and fixing means. As shown in FIG. 1, the stopper 5 is installed on the main body 40 on the base end side of the second flange 42.

In the syringe 1, when the pusher 4 is pressed and moved in the distal direction to discharge the medicine 100, the stopper 5 comes into contact with the base end portion (base end surface) 28 of the outer cylinder 2. The depth of insertion of the pusher 4 into the outer cylinder 2 is regulated, whereby an accurate amount of the medicine 100 can be discharged. The configurations of the stopper 5 and its fixing means will be described in detail below.

As shown in FIG. 2, the stopper 5 has a first
It is composed of a member 6 and a second member 7. Each of the first member 6 and the second member 7 has a substantially symmetrical configuration in FIG.

The first member 6 has a substantially box-shaped casing 61 whose lower side in FIG. 2 is open. As shown in FIG. 4, the left and right lower end portions of the casing 61 in the figure have sliding portions 62a, 6 having a substantially U-shaped cross section, respectively.
2b is formed to project. The first member 6 has a rail portion 44 in which the sliding portions 62a and 62b are provided on the pusher 4.
By sliding on 1, 451 it is possible to slide (move) along the longitudinal direction of the pusher 4.

In the present embodiment, as shown in FIG. 1, of the four plate pieces that cross each other in a cross shape forming the main body 40 of the pusher 4, the edges of two plate pieces 44 and 45 that are parallel to each other. The sections respectively constitute rail sections 441 and 451.
As shown in FIG. 5, the rail portions 441 and 451 are inserted inside the sliding portions 62a and 62b, respectively, and the inner surfaces of the sliding portions 62a and 62b slide along the rail portions 441 and 451. As a result, the first member 6 is guided along the longitudinal direction of the pusher 4.

As shown in FIG. 4, the sliding portions 62a, 62b
The lower surfaces of the sloping taper surfaces 621a and 621a are
It is 1b. Thus, when the first member 6 is mounted on the pusher 4 in the assembly process of the syringe 1, the rail portions 441, 45 are attached to the tapered surfaces 621a, 621b.
The sliding movement of 1 causes the sliding portions 62a and 62b to be elastically deformed so as to be spread, and can be easily mounted.

As shown in FIGS. 2 and 4, the central portions of the distal end wall 614 and the proximal end wall 615 of the casing 61 are
Grooves 611 and 612 are formed, respectively. In the grooves 611 and 612, the plate pieces 44 and 4 of the body 40 are formed.
The plate piece 46 orthogonal to 5 is inserted.

As shown in FIGS. 1 and 5, the plate piece 46 is provided with racks 47a and 47b having a plurality of engaging recesses 471 formed at predetermined intervals along the longitudinal direction of the pusher 4. There is. The stopper 5 is fixed to the pusher 4 by engaging the racks 47 a and 47 b with the engaging portions 63 a and 63 b provided on the first member 6.

In this embodiment, a pair of racks 47a and 47b and engaging portions 63a and 63b are provided. Thereby, the stopper 5 can be more reliably fixed to the pusher 4. A pair of racks 47a, 47
b are formed on both sides of the plate piece 46, respectively.

Engagement recess 4 in rack 47a, 47b
The formation interval (pitch) of 71 is not particularly limited and is appropriately set according to the capacity of the syringe 1 or the like, but, for example, the amount of liquid discharged from the syringe 1 is 0.1 mL increments, 0.2 mL increments, or 0.1 mL increments. It can be formed at intervals corresponding to 5 mL steps, 1 mL steps, 5 mL steps, 10 mL steps, and the like. In the configuration shown, the engagement recesses 471 are formed at intervals corresponding to the amount of discharged liquid in steps of 0.1 mL.

In the illustrated structure, the engaging recess 471 is formed of a substantially V-shaped groove. Thereby, the stopper 5 can be accurately fixed without rattling. Further, the plurality of engaging recesses 471 are formed adjacent to each other, and thus the racks 47a and 47b have a sawtooth shape.

In the present invention, the shape of the engaging recess 471 is not limited to that shown in the drawing, and may be, for example, a U-shaped, U-shaped, semicircular groove (recess) or hole. Good. The engaging recesses 471 are not limited to being formed adjacent to each other as shown in the figure, but may be formed intermittently at a predetermined interval.

As shown in FIG. 5, a pair of engaging portions 63a and 63b capable of engaging with the racks 47a and 47b are provided inside the casing 61.

As shown in FIG. 4, the engaging portions 63a, 6a
3b are respectively formed in the shape of arms protruding from the upper wall 613 of the casing 61 toward the inside of the casing 61.

As shown in FIG. 5, both engaging portions 63a, 63
The plate piece 46 is located between b. Engaging portion 63a,
On the lower end side of 63b, protrusions 631a and 631b having a substantially wedge shape (V-shape) corresponding to the shape of the engaging recess 471 are formed.
Are formed so as to project inward, and the protrusions 631a and 631b are inserted into the engaging recesses 471 of the racks 47a and 47b, respectively, so that they are engaged with each other.

Protrusion 631 in engaging portions 63a and 63b
Substantially hemispherical projections 632a and 632b are formed on the opposite side (outside) of the a and 631b.

Further, as shown in FIG. 2, a hole 64 is formed in the upper wall 613 outside the place where the engaging portions 63a and 63b are formed.
a and 64b are formed respectively.

As shown in FIG. 3, a cantilevered leaf spring (biasing means) 65 is integrally formed at the center of the upper wall 613. The leaf spring 65 has a curved shape, and a substantially hemispherical convex portion 651 protruding outward (upper side) is formed at the center thereof. In the natural state of the leaf spring 65, the convex portion 651 is in a state of protruding from the upper wall 613, and when the leaf spring 65 bends, the convex portion 651 sinks into the casing 61.

As shown in FIG. 2, the second member 7 includes a substantially plate-shaped operating portion 71, a pair of pressing portions 72a and 72b protruding from the lower surface of the operating portion 71 in the shape of an arm, and an operating portion. The projection 73 is formed on the upper surface of the portion 71.

The operation section 71 is a section that is pressed by a finger, that is, functions as a push button. Ridge 73
Has an anti-slip effect when the operating portion 71 is pressed with a finger. The pressing portions 72a and 72b are respectively engaged with the engaging portion 63.
It exerts a function of pressing a and 63b inward.

As shown in FIG. 5, the second member 7 is attached to the first member 6 with the pressing portions 72a and 72b inserted into the holes 64a and 64b, respectively. In this mounted state, the second member 7 causes the claws 723a and 723b formed on the pressing portions 72a and 72b to engage the claws 641a and 641b formed on the inner surfaces of the holes 64a and 64b, respectively.
The first member 6 is prevented from coming off (see FIGS. 2 and 4).

As shown in FIGS. 2 and 5, the pressing portion 72
A convex portion 721 protruding inward is provided at a lower end portion of each of a and 72b.
a and 721b are formed respectively. In addition, the convex portion 7
The upper sides of 21a and 721b are inclined tapered surfaces 722a and 722b, respectively.

As shown in FIG. 5, the second member 7 is always in a state where the operating portion 71 is floated (separated) from the upper wall 613 by the urging force of the leaf spring 65. When the operating portion 71 is pressed with a finger, as shown in FIG.
The second member 7 is displaced downward against the biasing force of the leaf spring 65, and the lower surface of the operation portion 71 contacts the upper wall 613.

In conjunction with the operation of the operation section 71, the pressing sections 72a and 72b are moved to the first position shown in FIG. 5 and the first position shown in FIG. 6 moved downward from the first position. And the position of 2.

As shown in FIG. 5, the pressing portions 72a, 72b
Is in the first position, that is, when the operating portion 71 is not being pressed, the convex portions 721a and 721b are
Is at the same position (height) as the convex portions 632a and 632b and presses them inward. As a result, the engaging portions 63a and 63b are respectively displaced inward, and the protrusion 63
1a and 631b are inserted into the engaging recesses 471 of the racks 47a and 47b, respectively. Thus, in the state shown in FIG. 5, the stopper 5 is fixed to the pusher 4 by the engagement between the engaging portions 63a and 63b and the racks 47a and 47b.

As shown in FIG. 6, the pressing portions 72a, 72b
Is in the second position, that is, when the operating portion 71 is pressed, the convex portions 721a and 721b are located below the convex portions 632a and 632b, and thus the convex portion 6
The pressure on 32a and 632b is released. As a result, the engaging portions 63a and 63b are displaced outward by their elasticity, and the protrusions 631a and 631b are attached to the rack 47a.
It retreats from the engaging recess 471 of 47b. Thus, in the state shown in FIG. 6, the fixation to the stopper 5 is released, and the stopper 5 slides (moves) with respect to the pusher 4.
can do.

When the pressing operation on the operation portion 71 is released from the state shown in FIG. 6, the second force is exerted by the leaf spring 65.
The member 7 is displaced upward, the pressing portions 72a and 72b return to the first position, and the fixed state shown in FIG. 5 is restored.
At this time, the convex portions 632a and 632b are not
By being pressed by the convex portions 721a and 721b while sliding on a and 722b, it is possible to smoothly return to the state shown in FIG. Particularly, in the illustrated configuration, the protrusion 632
Since the a and 632b have a hemispherical shape, friction with the tapered surfaces 722a and 722b is small, and this returning operation is performed more smoothly and reliably.

As described above, in the syringe 1, the stopper 5 is operated by pressing the operating portion 71 with a finger.
Can be slid on the pusher 4 to adjust its position. Further, when the finger is released from the operation portion 71 to release the pressing, the stopper 5 is fixed to the pusher 4 at that position. By adjusting the position of the stopper 5 on the pusher 4 in this manner, the depth of the pusher 4 that can be inserted into the outer cylinder 2 can be changed, and thus the amount of the medicine 100 to be discharged can be changed. It can be set to a desired amount.

In this embodiment, the racks 47a, 4a,
7b, the engaging portions 63a and 63b, the leaf spring 65 and the pressing portions 72a and 72b, the stopper 5 on the pusher 4.
The fixing means is configured to select and fix the position.

As shown in FIG. 1, the pusher 4 (plate piece 44)
Is provided with a scale 48 corresponding to the amount of liquid discharged from the syringe 1. As will be described later, stopper 5
The position of the tip surface 66 of the (first member 6) is set on the scale 48.
By pushing the pusher 4 in the state of being adjusted to, it is possible to discharge a desired amount of the medicine 100.

The scale 48 corresponds to the scale 27 of the outer cylinder 2, and is attached to a position corresponding to the discharged liquid amount of 0 to 5 mL in the illustrated configuration.

Further, the pusher 4 is provided with positioning means for positioning the stopper 5 at 0 (zero) of the scale 48. In the present embodiment, this positioning means is composed of the second flange 42. That is, the base end surface 421 of the second flange 42 is located at a position corresponding to 0 on the scale 48, whereby the stopper 5 is moved to the front end until the front end surface 66 of the stopper 5 contacts the base end surface 421 of the flange 42. By moving the stopper 5 in the direction, the stopper 5 can be easily aligned with the 0 of the scale 48 (zero point alignment). By performing the zero point adjustment, the discharged amount of the medicine 100 can be made more accurate as described later.

The positioning means is the flange 42.
However, the stopper 5 is not limited to the above structure and may be any structure as long as the stopper 5 is prevented from moving further in the front end direction. For example, a step formed on the edge of the plate piece 46 may be used.

The constituent material of the stopper 5 is not particularly limited, and in addition to the various synthetic resin materials mentioned as the constituent material of the outer cylinder 2, stainless steel, aluminum or an aluminum alloy, titanium or a titanium alloy, copper or copper. Various metal materials such as alloys can be used.

The fixing means for the stopper 5 is as follows.
Contrary to the configuration shown in the figure, on the engaging convex portion formed on the rack,
It may be such that an engaging portion formed of a recess provided in the stopper engages. In this case, the shape of the engaging protrusion of the rack is V-shaped, U-shaped, U-shaped, semicircular, or the like.
It may have any shape.

In addition, the second member 7 (pressing portions 72a, 72
The urging means for urging b) is not limited to the leaf spring 65, and any means may be used, and for example, it may be configured by another member such as a coil spring.

In this embodiment, a pair of racks 47 is used.
Although a and 47b and the engaging portions 63a and 63b are provided, in the present invention, one or three or more racks and engaging portions may be provided.

Next, an example of how to use the syringe 1 will be described. The method described below connects the syringe 1 to a holder (not shown) with a double-ended needle having a bottomed cylindrical holder body and a double-ended needle (needle tube) having sharp needle tips formed at both ends. In this example, the medicine 100 is mixed and injected into a bottle-shaped or bag-shaped infusion container (not shown).

[1A] First, set the stopper 5 to the scale 4
Align to 0 of 8 (zero point alignment). That is,
While pressing the operating portion 71 with a finger, the stopper 5 is moved to the tip end side of the pusher 4 as much as possible, and the tip end surface 66 is brought into contact with the base end surface 421 of the second flange 42. As described above, when the finger is released from the operation portion 71, the stopper 5 is fixed at that position on the pusher 4.

[2A] Next, the air in the outer cylinder 2 is evacuated as follows. As shown in FIG. 1, the syringe 1 is filled with a slightly larger amount of the medicine 100 than a prescribed amount (5 mL in the illustrated configuration). The holder 29 of the holder with double-ended needle is fitted (covered) onto the cap 29 of the syringe 1. As a result, one of the tips of the double-ended needle is attached to the membrane 24.
And penetrates into the inner cavity 23 of the reduced diameter portion 22. After mounting the holder with a double-headed needle in this way, put a finger on the finger contact portion 401 of the pusher 4, and push the pusher 4 until the tip surface 66 of the stopper 5 contacts the base end portion 28 of the outer cylinder 2. The outer cylinder 2 is moved in the front end direction. As a result, the gasket 3 connected to the pusher 4 slides in the tip direction in the outer cylinder 2,
The drug 100 and the air in the outer cylinder 2 in excess of the specified amount are discharged through the inner cavity 23 of the reduced diameter portion 22 and the double-ended needle.

By this operation, the medicine 100 in the outer cylinder 2 becomes the specified amount. That is, in this state, the gasket 3
The tip of the outer peripheral portion (convex portion 33) is located at a specified amount (5 mL in the illustrated configuration) on the scale 27 of the outer cylinder 2.

[3A] Next, the other needle tip of the double-ended needle of the double-ended needle holder is pierced through the stopper that seals the mouth of the infusion container. In this state, the inside of the outer cylinder 2 and the internal space of the infusion container communicate with each other via a double-ended needle.

[4A] Next, while pressing the operating portion 71 with a finger, the stopper 5 is slid on the pusher 4, and the tip end surface 66 of the stopper 5 is moved to a position on the scale 48 corresponding to a desired discharge amount. To match. For example, in the illustrated configuration, when discharging 1 mL of the drug 100, the tip surface 66
When aligning the “1” on the scale 48 and discharging 3 mL of the medicine 100, set the tip surface 66 to “3” on the scale 48.
To match.

[5A] Next, press the pusher 4 toward the tip end with a finger on the finger rest 401, until the tip end surface 66 of the stopper 5 comes into contact with the base end portion 28 of the outer cylinder 2. Is moved in the front end direction with respect to the outer cylinder 2. This allows
The gasket 3 connected to the pusher 4 slides in the outer cylinder 2 in the distal direction, and a set amount of the medicine 100 is discharged from the outer cylinder 2 through the inner cavity 23 of the reduced diameter portion 22 and the double-ended needle. Is
It is added to the infusion solution in the infusion container.

As described above, according to the present invention, the stopper 5 is brought into contact with the outer cylinder 2 so that the insertion depth of the pusher 4 into the outer cylinder 2 is restricted. It is possible to accurately discharge the set amount of the medicine 100 without insufficient pressure. Therefore, it is possible to reliably prevent the mistake in which the discharge amount of the medicine 100 is excessive or excessive.

In the syringe 1, the stopper 5 can be unlocked and the position on the pusher 4 can be adjusted by a one-touch operation of pressing the operating portion 71 with a finger. Thereby, the setting operation of the discharge amount of the medicine 100 can be performed extremely easily and quickly.

Further, when the pressing operation on the operation portion 71 is released, the stopper 5 is automatically returned to the fixed state, so that the position of the stopper 5 once set does not deviate and the set discharge amount does not change. .

In the discharge operation of the medicine 100,
The above effect can be achieved by a simple operation of moving the pusher 4 in the distal direction until the stopper 5 hits the outer cylinder 2, and the operation of the pusher 4 does not require delicate force adjustment. It's easy.

In addition to the above-described usage method, a usage method in which an excessive amount of the drug 100 is discarded beforehand can be adopted as follows.

[1B] In the illustrated configuration, the specified amount is 5
The case where only 3 mL of mL is used will be described as an example. First, the tip surface 66 of the stopper 5 is attached to the medicine 1 on the scale 48.
Set to the position corresponding to the excess amount of 00. In this case, the used amount is 3 mL and the used amount is 2 mL with respect to the prescribed amount of 5 mL, so that the tip surface 66 is adjusted to "2" of the scale 48.

[2B] Next, after attaching the holder with a double-ended needle to the cap 29 of the syringe 1 in the same manner as described above, a finger is put on the finger contact portion 401 of the pusher 4 so that the tip surface 66 of the stopper 5 is the outer cylinder. Until it abuts on the base end 28 of 2.
The pusher 4 is moved in the distal direction with respect to the outer cylinder 2. As a result, the gasket 3 connected to the pusher 4 slides in the distal direction in the outer cylinder 2, and the excessive amount of the medicine 100 and the air in the outer cylinder 2 cause the lumen 23 of the reduced diameter portion 22 and the double-ended needle. It is discharged through the inside. As a result, air is removed and
3 mL of the drug 100 remains in the outer cylinder 2. That is, in this state, the tip of the outer peripheral portion of the gasket 3 (the convex portion 33)
Is located at “3” on the scale 27 of the outer cylinder 2.

[3B] Next, similarly to the above, the other needle tip of the double-ended needle of the double-ended needle holder is pierced into the plug body that seals the mouth of the infusion container, and the inside of the outer cylinder 2 and the internal space of the infusion container are inserted. And communicate with.

[4B] Next, while pressing the operating portion 71 with a finger, the stopper 5 is slid on the pusher 4 to move the stopper 5 to the base end portion of the pusher 4 (in the configuration shown, the scale 48 "5 "To the base end side).

[5B] Next, the pusher 4 is pressed by putting a finger on the finger rest 401, and the pusher 4 is pressed until the tip end surface 36 of the gasket 3 comes into contact with (or approaches) the bottom 21 of the outer cylinder 2.
Of the drug 100 remaining in the outer cylinder 2 by moving the
Discharge almost all of the. As a result, the desired amount (3
(mL) drug 100 can be added to the infusion solution in the infusion container.

In this embodiment, the liquid medicine 100 is used.
I explained the syringe 1 that was stored in advance,
In the present invention, the drug 100 may be solid. In this case, the pusher 4 is pulled in the proximal direction, the liquid is sucked from the tip opening of the reduced diameter portion 22 and introduced into the outer cylinder 2, and the drug 100 is dissolved in the liquid for use. Further, the present invention is
The invention is not limited to the prefilled syringe such as the syringe 1, but can be applied to a normal syringe in which a drug or the like is not enclosed.

Further, in the present embodiment, the operation section 71 is operated by pressing with a finger, but in the present invention, a pulling operation (pulling operation) or a pinching operation (pinching operation) with the finger is performed. Alternatively, the fixing of the stopper 5 may be released by performing the operation.

The syringe 1 is not limited to the method of using the holder with the double-headed needle as described above, but the reduced diameter portion 22 is fitted with, for example, a needle tube hub, connectors, tubes or the like (not shown). Needless to say, it may be attached and used.

<Second Embodiment> FIG. 7 is a perspective view showing a main body of a pusher and a stopper in a second embodiment of the syringe of the present invention.

The second embodiment of the syringe of the present invention will be described below with reference to this figure, but the description will focus on the differences from the above-mentioned embodiment, and the description of the same items will be omitted.

The pusher 4A of this embodiment is used for a syringe having a larger size (larger capacity) than the syringe 1 of the first embodiment. That is, the pusher 4A is the first
It is larger than the pusher 4 of the embodiment.

The main body 40A of the pusher 4A is formed by crossing plate pieces in a cross shape. This body 40A
A stopper 5 similar to the one described above is installed in the. The width (maximum width) of the stopper 5 is smaller than the width (maximum width) of the main body portion 40A.

From both sides of one plate piece 46A of the four plate pieces constituting the main body 40A, the plate pieces 44A, 45A are
Are formed to project. That is, the plate pieces 44A, 45A
Intersects the plate piece 46A in a cross shape. Rail portions 441 and 451 with which the stopper 5 slides are configured by the edge portions of the plate pieces 44A and 45A.

Racks 47a and 47b are provided on both sides of the plate piece 46A located above the plate pieces 44A and 45A in FIG.

As described above, in the present embodiment, the main body 40
A stopper 5 having a maximum width smaller than the maximum width of A (presser 4A) can be installed and used. Therefore, for example, the stopper 5 having the same size and configuration as in the first embodiment can be installed and used in the pusher 4A larger than that in the first embodiment. Therefore, when the present invention is applied to a large-sized syringe, it is possible to use the same one as the stopper 5 for a small-sized syringe, so that it is not necessary to newly design and manufacture a large-sized stopper, so that the manufacturing cost can be reduced. Can be reduced. Further, the weight of the syringe can be reduced as compared with the case where a large-sized stopper is installed, and thus it is possible to prevent adverse effects due to an increase in weight, such as deterioration of operability.

<Third Embodiment> FIGS. 8 and 9 are partial cross-sectional perspective views showing a main body portion and a stopper of a pusher in a third embodiment of the syringe of the present invention. For convenience of explanation, the upper side in FIGS. 8 and 9 is referred to as “upper” and the lower side is referred to as “lower”.

The third embodiment of the syringe of the present invention will be described below with reference to these drawings, but the description will focus on the differences from the above-mentioned embodiment, and the description of the same items will be omitted.

This embodiment is the same as the first embodiment except that the structure of the fixing means for fixing the stopper to the pusher is different.

In the present embodiment, the plate pieces 44, 4 of the pusher 4 are
5, ridges extending in the longitudinal direction are formed at the edges of 5, respectively,
The ridges form racks 442 and 452.

A plurality of engaging recesses 443, 4 are formed on the surfaces of the racks 442, 452 facing the plate piece 46, respectively.
53 are formed at predetermined intervals. In the configuration shown in the drawing, the engaging recesses 443 and 453 are formed by a substantially U-shaped groove.

The stopper 5A includes a first member 6 and a second member 6.
And the member 7. Base end wall 6 of first member 6
From 15, the engaging portion 6 that engages with the racks 442 and 452
Each of 7a and 67b is formed so as to extend like an arm in the distal direction. The engaging portion 67 a is located between the rack 442 and the plate piece 46, and the engaging portion 67 b is located in the rack 4.
It is located between 52 and the plate piece 46.

Protrusions 671a and 671 that can be inserted into the engaging recesses 443 and 453 are provided at the tips of the engaging portions 67a and 67b.
Each of b is formed so as to project outward. The protrusions 671a and 671b are substantially U-shaped (semi-cylindrical).

On the upper wall 613 of the first member 6, the leaf spring 6 is
Holes 68a and 68b are formed on both sides of the plate 5, respectively.

From the lower surface of the operating portion 71 of the second member 7,
The pressing portions 74a and 74b are formed to project like arms. The second member 7 is provided with the pressing members 74a and 74b inserted into the holes 68a and 68b, respectively.
It is installed in. In this mounted state, the pressing parts 74a, 7
The tip side of 4b is located inside the engaging parts 67a and 67b, respectively.

Projecting portions 741a and 741b are formed on the lower ends of the pressing portions 74a and 74b so as to project outward. The upper sides of the convex portions 741a and 741b are inclined tapered surfaces 742a and 742b, respectively.

In this embodiment, the racks 442, 452,
Engaging portions 67a, 67b, leaf spring 65 and pressing portion 74
A and 74b constitute a fixing means for fixing the stopper 5A to the pusher 4.

In the second member 7, as shown in FIG. 8, the operation portion 71 is always operated by the urging force of the leaf spring 65 as shown in FIG.
It is in a state of being floated (separated) from No. 3. And
When the operating portion 71 is pressed with a finger, as shown in FIG.
The member 7 is displaced downward against the urging force of the leaf spring 65, and the lower surface of the operation portion 71 contacts the upper wall 613.

Interlocking with the operation of the operation section 71, the pressing sections 74a and 74b are moved to the first position shown in FIG. 8 and the first position shown in FIG. 9 moved downward from the first position. And the position of 2.

As shown in FIG. 8, the pressing portions 74a, 74b
Is in the first position, that is, when the operation portion 71 is not being pressed, the convex portions 741a and 741b
Is at the same position (height) as the engaging portions 67a and 67b and presses them outward. As a result, the engaging portions 67a and 67b are respectively displaced outward, and the protrusion 67
1a and 671b are inserted into the engaging recesses 443 and 453 of the racks 442 and 452, respectively. In this way, FIG.
In the state shown in, the engaging portions 67a and 67b and the rack 44 are
By engaging with 2, 452, the stopper 5A
Are fixed to the pusher 4.

As shown in FIG. 9, the pressing portions 74a, 74b
Is in the second position, that is, when the operating portion 71 is pressed, the convex portions 741a and 741b are located below the engaging portions 67a and 67b, and therefore, the engaging portion 6
The pressure on 7a and 67b is released. This allows
The engaging portions 67a and 67b are displaced inward by their own elasticity, and the protrusions 671a and 671b are attached to the racks 442 and 45.
It retreats from the second engagement recesses 443 and 453. As described above, in the state shown in FIG. 9, the fixing to the stopper 5A is released, and the stopper 5A can slide (move) with respect to the pusher 4.

When the pressing operation on the operation portion 71 is released from the state shown in FIG. 9, the second spring is moved by the urging force of the leaf spring 65.
The member 7 is displaced upward, the pressing portions 74a and 74b return to the first position, and the fixed state shown in FIG. 8 is restored.
At this time, the engagement portions 67a and 67b are not attached to the tapered surface 742.
By being pressed by the convex portions 741a and 741b while sliding on a and 742b, the state shown in FIG. 8 can be smoothly restored.

As described above, in this embodiment, similarly to the first embodiment, the stopper 5A can be slid on the pusher 4 by pressing the operation portion 71 with a finger, and the stopper 5A can be easily moved. The position can be adjusted.

<Fourth Embodiment> FIGS. 10 and 11 show
It is a partial cross-sectional perspective view which shows the pusher and stopper in 4th Embodiment of the syringe of this invention, respectively. For convenience of explanation, the upper side in FIGS. 10 and 11 is referred to as “upper” and the lower side is referred to as “lower”.

Hereinafter, the fourth embodiment of the syringe of the present invention will be described with reference to these drawings, but the description will focus on the differences from the above-mentioned embodiment, and the description of the same matters will be omitted.

This embodiment is the same as the first embodiment except that the structure of the fixing means for fixing the stopper to the pusher is different.

In the present embodiment, a plurality of engaging recesses 462 are formed at predetermined intervals along the longitudinal direction at the edge of the plate piece 46 of the pusher 4, whereby the rack 461 is constituted. . The engaging recess 462 is formed by a substantially V-shaped notch (groove), and the rack 461 has a saw-tooth shape.

The stopper 5B includes the first member 6 and the second member 6.
It is composed of the member 8 and the third member 9. In FIGS. 8 and 9, the first member 6 and the second member 8 are
It is shown in a state of being cut at the center of the syringe 1 in the longitudinal direction.

The inner structure of the stopper 5B is symmetrical with respect to the front end side and the base end side. That is, FIG. 8 and FIG.
Then, although only the front end side of the first member 6 and the second member 8 is shown, the base end side is formed symmetrically with the front end side.

The second member 8 is a plate-shaped (bar-shaped) main body 8
1, and the main body 81 is installed in the casing 61 of the first member 6 in a state of being inserted from the side. At the end of the main body 81, an operation unit 8 that functions as a push button
2 are installed. That is, the operating portion 82 is provided on the side of the stopper 5B.

The body 81 is provided with a pair of leaf springs 84, 84 projecting toward the front end side and the base end side, respectively. The leaf spring 84 is formed integrally with the main body 81. The tip of the leaf spring 84 is in contact with the inner wall of the casing 61.

Further, an engaging portion (projection) 83 capable of engaging with the rack 461 is formed on the main body 81 so as to project downward. The engaging portion 83 has a wedge shape (V shape) corresponding to the engaging recess 462.

The third member 9 serves as a lid for the first member 6, and has a substantially plate-like lid portion 91 and a lid portion 91.
A plurality of protrusions (four in the illustrated configuration) formed from the lower surface of the
Has a claw portion 92. The first member 6 (casing 61) has holes 6 at positions corresponding to the claws 92, respectively.
16 is formed, and by inserting and fitting the claw portion 92 into this hole 616, the third member 9 becomes the first member 6.
Be attached to. By mounting the third member 9,
The second member 8 is prevented from coming off the first member 6.

In this embodiment, the rack 461 and the engaging portion 8
3 and the leaf spring 84, push the stopper 5B
The fixing means for fixing to.

As shown in FIG. 10, when the operation portion 82 is not pressed, the left side of the body portion 81 in the figure is in a state of protruding from the casing 61 by the urging force of the leaf spring 84. . In this state, the engaging portion 83 is located at the position inserted into the engaging recess 462 of the rack 461, whereby the stopper 5B is fixed to the pusher 4.

When the operating portion 82 is pressed from this state,
As shown in FIG. 11, the leaf spring 84 bends and the main body 81
Moves so as to be immersed in the casing 61. By this movement of the main body 81, the engaging portion 83 is moved to the rack 461.
To the side of. As a result, in the state shown in FIG. 11, the fixation to the stopper 5B is released, and the stopper 5B can slide (move) with respect to the pusher 4.

When the pressing operation on the operating portion 82 is released from the state shown in FIG. 11, the second member 8 (main body portion 81) is displaced by the urging force of the leaf spring 84 and the state returns to the fixed state shown in FIG. .

As described above, in this embodiment, similarly to the first embodiment, the stopper 5B can be slid on the pusher 4 by pressing the operating portion 82 with the finger, and the stopper 5B can be easily moved. The position can be adjusted. At this time, in the present embodiment, since the operating portion 82 is provided on the side of the stopper 5B, the operating portion 82 can be pressed by sandwiching the stopper 5B from both sides with two fingers. As a result, the stopper 5B
The position on the pusher 4 can be adjusted by sliding the pinched (pinched) state with two fingers, and this operation can be performed more easily.

Although the syringe of the present invention has been described with reference to the illustrated embodiment, the present invention is not limited to this, and each part constituting the syringe has an arbitrary structure capable of exhibiting the same function. Can be replaced.

[0148]

As described above, according to the present invention, it is possible to discharge an accurate amount of liquid with a simple operation, and it is possible to reliably prevent an error that the discharge amount is too large or too small. it can.

Further, the stopper can be unlocked and the position on the pusher can be adjusted by a simple operation such as pushing, pulling or pinching the operating portion. The setting operation can be performed extremely easily and quickly.

When the operation on the operation unit is released,
Since the stopper is automatically returned to the fixed state, the position of the stopper once set does not shift and the set discharge amount does not change.

Further, in the liquid discharging operation, the above effect can be achieved by a simple operation of moving the pusher in the tip direction until the stopper contacts the outer cylinder.
It does not require delicate force to operate the pusher and has excellent operability.

[Brief description of drawings]

FIG. 1 is a partial vertical cross-sectional view showing a first embodiment of a syringe of the present invention.

2 is a perspective view (disassembled state) of a stopper in the syringe shown in FIG. 1. FIG.

FIG. 3 is a sectional view taken along line XX in FIG.

4 is a cross-sectional view taken along the line YY in FIG.

5 is a partial cross-sectional perspective view (fixed state) showing a main body portion and a stopper of the pusher in the syringe shown in FIG.

6 is a partial cross-sectional perspective view showing a main body portion and a stopper of the pusher in the syringe shown in FIG. 1 (fixed state).
Is.

FIG. 7 is a perspective view showing a main body portion and a stopper of a pusher in a second embodiment of the syringe of the present invention.

FIG. 8 is a partial cross-sectional perspective view (fixed state) showing a main body portion and a stopper of a pusher in a third embodiment of the syringe of the present invention.

FIG. 9 is a partial cross-sectional perspective view (fixed state) showing a main body portion and a stopper of a pusher in a third embodiment of the syringe of the present invention.

FIG. 10 is a partial cross-sectional perspective view (fixed state) showing a pusher and a stopper in a fourth embodiment of the syringe of the present invention.

FIG. 11 is a partial cross-sectional perspective view (fixed state) showing a pusher and a stopper in a fourth embodiment of the syringe of the present invention.

[Explanation of symbols]

1 syringe 2 outer cylinder 21 bottom 22 Reduced diameter 23 Lumen 24 membranes 25 flange 26 Inner surface 27 scale 28 Base end 29 caps 291 opening 3 gasket 31, 32, 33 convex 34 Hollow part 341 female screw 36 Tip surface 4 pusher 40, 40A main body 401 finger rest 41 First Flange 42 Second flange 43 Head 431 male screw 44, 44A, 45, 45A, 46, 46A Plate piece Rails 441, 451 442, 452, 461 racks 443, 453, 462 Engagement recess 47a, 47b rack 48 scale 5, 5A, 5B stopper 6 First member 61 casing 611 and 612 grooves 613 upper wall 614 Tip wall 615 Base wall 616 holes 62a, 62b sliding part 621a, 621b Tapered surface 63a, 63b Engagement part 631a, 631b protrusion 632a, 632b convex portion 64a, 64b holes 641a, 641b claws 65 leaf spring 651 convex 66 Tip surface 67a, 67b Engagement part 671a, 671b Protrusion 68a, 68b holes 7 Second member 71 Operation part 72a, 72b Pressing part 721a, 721b Convex part 722a, 722b Tapered surface 723a, 723b nails 73 ridge 74a, 74b Pressing part 741a, 741b Convex part 742a, 742b Tapered surface 8 Second member 81 Main body 82 Operation part 83 Engagement part 84 leaf spring 9 Third member 91 Lid 92 Claw 100 drugs

   ─────────────────────────────────────────────────── ─── Continued front page    (72) Inventor Hiromitsu Okabe             2-44-1 Hatagaya, Shibuya-ku, Tokyo             Mo Co., Ltd. F-term (reference) 4C066 AA09 BB01 CC01 DD08 EE14                       HH12 HH17 HH22 LL21 QQ32

Claims (10)

[Claims] 1. An outer cylinder, a gasket slidable in the outer cylinder, a pusher inserted through a base end opening of the outer cylinder to move the gasket, and a longitudinal direction of the pusher. A stopper that is slidably installed along with, a fixing unit that selects and fixes the position of the stopper on the pusher, and an operation unit that is provided on the stopper and that performs a pressing operation, a pulling operation, or a clamping operation. The position of the stopper on the pusher can be adjusted by releasing the fixing of the fixing means by the operation of the operation portion, and the stopper contacts a part of the outer cylinder. The insertion depth of the pusher into the outer cylinder is regulated by the above. 2. The syringe according to claim 1, wherein the fixing unit is configured to return to a fixed state by elasticity when the operation on the operation unit is released. 3. The rack, wherein the fixing means is provided on the pusher, and has a plurality of engaging concave portions or engaging convex portions formed at predetermined intervals along the longitudinal direction of the pusher, and the stopper. An engaging portion is provided that is displaceable between a state in which it is engaged with the rack and a state in which it is retracted from the rack, and the engaging portion is always engaged with the rack, and The syringe according to claim 1 or 2, which is retracted from the rack by the operation of. 4. The fixing means is interlocked with the operation section,
First for pressing the engaging portion in a direction of engaging the rack
And a urging means for urging the urging portion so as to come to the first position, and the fixing means is normally provided. , The pressing portion is in the first position, the engaging portion is in a state of engaging the rack and fixing the stopper, and when the operating portion is operated, the pressing portion is in the second position. When the engaging portion retracts from the rack and the fixation is released by moving to the position, and the operation on the operation portion is released, the stopper is returned to the fixed state by the urging force of the urging means. 4. The syringe of claim 3, which operates as follows. 5. The fixing means has urging means for urging the engaging portion to be displaced from a state of retracting from the rack to a state of being engaged with the rack, and the engaging portion is normally provided. Is engaged with the rack and the stopper is fixed, and when the operation part is operated, the engagement part retracts from the rack and the fixation is released, and the operation on the operation part is released. Then, the syringe according to claim 3, which is operated by the urging force of the urging means so as to return to the state in which the stopper is fixed. 6. The pusher according to claim 3, wherein the pusher has a main body formed by intersecting plate pieces in a cross shape, and the rack is formed on a part of the plate piece. The syringe described. 7. The pusher has a rail portion, the stopper has a sliding portion that slides along the rail portion, and the sliding portion guides on the rail portion. The syringe according to any one of claims 1 to 6, which slides along the longitudinal direction of the pusher. 8. The syringe according to claim 1, wherein the pusher is provided with a scale indicating the position of the stopper corresponding to the discharged liquid amount. 9. The syringe according to claim 8, wherein the pusher has positioning means for positioning the stopper at a position of 0 on the scale. 10. The syringe according to claim 1, wherein a drug is previously stored in a space surrounded by the outer cylinder and the gasket.