JP2003190206A - Wound protective agent and manufacturing method therefor - Google Patents

Wound protective agent and manufacturing method therefor

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Publication number
JP2003190206A
JP2003190206A JP2001400101A JP2001400101A JP2003190206A JP 2003190206 A JP2003190206 A JP 2003190206A JP 2001400101 A JP2001400101 A JP 2001400101A JP 2001400101 A JP2001400101 A JP 2001400101A JP 2003190206 A JP2003190206 A JP 2003190206A
Authority
JP
Japan
Prior art keywords
water
gel
wound
support
layer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2001400101A
Other languages
Japanese (ja)
Other versions
JP3973420B2 (en
Inventor
Shusuke Yokoi
秀輔 横井
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Life Care Giken Inc
Tac Kasei KK
Original Assignee
Life Care Giken Inc
Tac Kasei KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Life Care Giken Inc, Tac Kasei KK filed Critical Life Care Giken Inc
Priority to JP2001400101A priority Critical patent/JP3973420B2/en
Publication of JP2003190206A publication Critical patent/JP2003190206A/en
Application granted granted Critical
Publication of JP3973420B2 publication Critical patent/JP3973420B2/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

<P>PROBLEM TO BE SOLVED: To provide a wound protective agent, capable of facilitating manufacture, lowering the cost and presenting convenience for use, preventing adhesion to the skin tissue, and continuing the sterilizing effect for long time, and a manufacturing method therefor. <P>SOLUTION: A pad part 25 is provided with a water-contained gel layer 16 in which a sterilizing disinfectant is dissolved. The water-contained gel layer 16 is held by a gel support 18, and the gel support 18 is held by a pressure sensitive support material 12. The water-contained gel layer 16 contains chemical such as ethyl alcohol or water soluble sterilizing disinfectant. The water- contained gel layer 16 is composed of water soluble high polymer material such as high polymer polysaccharide dissolved by heating or solidified by cooling. <P>COPYRIGHT: (C)2003,JPO

Description

【発明の詳細な説明】Detailed Description of the Invention

【0001】[0001]

【発明の属する技術分野】この発明は、絆創膏やドレッ
シング剤等、身体の傷面を覆い保護する創傷保護剤とそ
の製造方法に関する。
BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a wound protector for covering and protecting a wound surface of a body such as a plaster and a dressing and a method for producing the same.

【0002】[0002]

【従来の技術】従来、例えば特開昭59−139267
号公報に開示されているように、ゼラチンや寒天に消毒
剤を混合してゼリー化し、皮膚表面の殺菌消毒洗浄を目
的としたゼリー状消毒剤が提案されている。また、殺菌
消毒溶液をブリスターパックし、使用時にこのパックを
破壊して薬液をパッド部に染み込ませて使用する傷絆創
膏等も提案されている。
2. Description of the Related Art Conventionally, for example, JP-A-59-139267.
As disclosed in the publication, a jelly-like disinfectant has been proposed for the purpose of sterilizing and disinfecting the skin surface by mixing gelatin or agar with a disinfectant to form a jelly. In addition, a wound plaster or the like has been proposed in which a sterilizing / disinfecting solution is blister-packed and the pack is destroyed at the time of use to allow the drug solution to soak into the pad portion for use.

【0003】[0003]

【発明が解決しようとする課題】上記従来技術では、製
造コストが高く、製品の長期安定性や使用時にパックを
破壊する等の操作が難しい等の欠点があった。
The above-mentioned conventional techniques have drawbacks such as high manufacturing cost, long-term stability of the product, and difficulty in operation such as breaking the pack during use.

【0004】この発明は上記従来の問題点に鑑みてなさ
れたもので、製造が容易であり、コストも安価で、使用
しやすく、殺菌効果を長時間持続することができる創傷
保護剤とその製造方法を提供することを目的とする。
The present invention has been made in view of the above conventional problems, and is easy to manufacture, inexpensive, easy to use, and capable of sustaining a bactericidal effect for a long time. The purpose is to provide a method.

【0005】[0005]

【課題を解決するための手段】この発明は、パッド部に
殺菌消毒剤を溶解した含水ゲル層を有する創傷保護剤で
ある。上記含水ゲル層はゲル支持体に保持され、このゲ
ル支持体は粘着剤支持材に保持されており、上記含水ゲ
ル層、ゲル支持体、粘着剤支持材はいずれも透明な材料
で形成されていても良い。
The present invention is a wound protector having a water-containing gel layer in which a bactericidal disinfectant is dissolved in a pad portion. The water-containing gel layer is held by a gel support, the gel support is held by a pressure-sensitive adhesive support material, the water-containing gel layer, the gel support, the pressure-sensitive adhesive support material are all formed of a transparent material. May be.

【0006】上記含水ゲル層は、エチルアルコール又は
水溶性殺菌消毒剤等の薬剤を含むものである。また、上
記含水ゲル層は、加熱して溶解し、冷却により固化する
高分子多糖類等の水溶性高分子材料から成る。上記水溶
性高分子材料は、マンナン、寒天、ゼラチン、ジェラン
ガム、ポリビニルピロリドン、アラビアゴム、またはト
ラガントゴムから選ばれた一または複数の材料から成る
高分子である。
The hydrous gel layer contains a drug such as ethyl alcohol or a water-soluble germicidal disinfectant. The water-containing gel layer is made of a water-soluble polymer material such as a polymer polysaccharide that is dissolved by heating and solidified by cooling. The water-soluble polymer material is a polymer composed of one or more materials selected from mannan, agar, gelatin, gellan gum, polyvinylpyrrolidone, gum arabic, or gum tragacanth.

【0007】また、上記含水ゲル層は、化学反応により
固化する水溶性高分子材料から成る。上記水溶性高分子
材料は、アルギン酸ナトリウム、またはポリビニルアル
コールを含む合成高分子である。
The water-containing gel layer is made of a water-soluble polymer material which is solidified by a chemical reaction. The water-soluble polymer material is a synthetic polymer containing sodium alginate or polyvinyl alcohol.

【0008】上記ゲル支持体は、不織布、織布、または
ナイロンネットである。上記含水ゲル層は、樹脂フィル
ムで成形した浅い容器内に設けられている。
The gel support is a non-woven fabric, a woven fabric, or a nylon net. The hydrous gel layer is provided in a shallow container formed of a resin film.

【0009】また、粘着剤支持材は、不織布、織布、樹
脂フィルム等であり、粘着剤を塗布可能なものであれば
よい。特に、織布や不織布で構成した場合、含水ゲル層
からの水分蒸発を促進し、創傷面の冷却効果が高くな
る。
The pressure sensitive adhesive support material may be a non-woven fabric, a woven fabric, a resin film or the like, as long as the pressure sensitive adhesive can be applied. In particular, when it is made of a woven fabric or a non-woven fabric, it promotes the evaporation of water from the hydrogel layer and enhances the cooling effect on the wound surface.

【0010】またこの発明は、含水ゲルを構成する水溶
性高分子溶液を、ゲル支持体の片面に部分的に吸着浸透
させ、ゲル化後、上記ゲル支持体を粘着剤支持材の粘着
剤層に貼り付ける創傷保護剤の製造方法である。上記含
水ゲル層は、シート状の上記ゲル支持体上に一体に形成
し、打ち抜きにより所定の大きさに形成し、このゲル支
持体を粘着剤支持材の粘着剤層に貼付するものである。
Further, according to the present invention, a water-soluble polymer solution constituting a hydrous gel is partially adsorbed and permeated on one surface of a gel support, and after gelation, the gel support is used as an adhesive layer of an adhesive support material. It is a method for producing a wound protection agent to be attached to. The hydrous gel layer is formed integrally on the sheet-like gel support, punched to a predetermined size, and attached to the pressure-sensitive adhesive layer of the pressure-sensitive adhesive support material.

【0011】[0011]

【発明の実施の形態】以下、この発明の実施の形態につ
いて図面に基づいて説明する。図1,図2はこの発明の
第一実施形態を示すもので、この実施形態の創傷保護剤
10は、長方形の薄いポリエステル等のフィルムやテー
プ、その他薄い織布や不織布等から成る粘着剤支持材1
2と、この粘着剤支持材12の一面に設けられた粘着剤
層14、及びこの粘着剤層14が形成された側の面の中
央部に設けられた含水ゲル層16を備えている。含水ゲ
ル層16は、ゲル支持体18に保持されてパッド部15
を形成し、粘着剤層14に貼り付けられている。
BEST MODE FOR CARRYING OUT THE INVENTION Embodiments of the present invention will be described below with reference to the drawings. 1 and 2 show a first embodiment of the present invention. A wound protection agent 10 of this embodiment is a rectangular film or tape made of thin polyester or the like, and an adhesive support made of thin woven cloth or nonwoven cloth. Material 1
2, a pressure-sensitive adhesive layer 14 provided on one surface of the pressure-sensitive adhesive support material 12, and a hydrous gel layer 16 provided at the center of the surface on the side where the pressure-sensitive adhesive layer 14 is formed. The hydrous gel layer 16 is held by the gel support 18 and is held by the pad portion 15.
And is attached to the pressure-sensitive adhesive layer 14.

【0012】粘着剤層14は、一面に形成されていても
良いが、ウエブ塗工等により粘着剤支持材12の面に部
分的に形成されていることにより通気性を有し、含水ゲ
ル層16の水分蒸発を妨げない。
The pressure-sensitive adhesive layer 14 may be formed on one surface, but since it is partially formed on the surface of the pressure-sensitive adhesive support material 12 by web coating or the like, the pressure-sensitive adhesive layer 14 has air permeability and has a hydrogel layer. 16 does not interfere with water evaporation.

【0013】また、粘着剤支持材12、粘着剤層14、
含水ゲル層16、及びゲル支持体18を全て透明な材料
で形成することにより、本発明の創傷保護剤10を貼付
した状態で、患部を外部から観察することができる。
Further, the adhesive support material 12, the adhesive layer 14,
By forming all of the hydrous gel layer 16 and the gel support 18 with a transparent material, the affected area can be observed from the outside with the wound protective agent 10 of the present invention attached.

【0014】含水ゲル層16は、加熱して溶解し、冷却
により固化する高分子多糖類の水溶性高分子材料から成
る。この水溶性高分子材料としては、マンナン、寒天、
ゼラチン、ジェランガム、ポリビニルピロリドン、アラ
ビアゴム、またはトラガントゴムから選ばれた一または
複数の材料から成る。ゲル形成材の配合量は、全体の
0.1〜5%程度である。
The water-containing gel layer 16 is made of a water-soluble polymer material which is a polymer polysaccharide that is melted by heating and solidified by cooling. As the water-soluble polymer material, mannan, agar,
It is composed of one or more materials selected from gelatin, gellan gum, polyvinylpyrrolidone, acacia, or tragacanth. The blending amount of the gel forming material is about 0.1 to 5% of the whole.

【0015】また、含水ゲル層16の材料は、化学反応
によりゲル化する水溶性高分子材料であっても良い。こ
の水溶性高分子材料は、アルギン酸ナトリウム、または
ポリビニルアルコールを含む合成高分子である。
Further, the material of the hydrous gel layer 16 may be a water-soluble polymer material which gels by a chemical reaction. This water-soluble polymer material is a synthetic polymer containing sodium alginate or polyvinyl alcohol.

【0016】ゲル支持体18は、不織布、織布の薄い布
で、目付量が30〜100g/m、好ましくは50〜
70g/mで、伸縮性のある不織布が最も好ましい。
ゲル支持体18を形成する繊維は、ポリエステル、ポリ
プロピレン、アクリル等の合成繊維の他、レーヨン、パ
ルプ、コットン等の繊維も使用し得る。またはナイロン
ネットを用いても良い。
The gel support 18 is a thin cloth such as a non-woven fabric or a woven fabric, and has a basis weight of 30 to 100 g / m 2 , preferably 50 to
Most preferred is a stretchable nonwoven fabric at 70 g / m 2 .
As the fibers forming the gel support 18, synthetic fibers such as polyester, polypropylene and acrylic as well as fibers such as rayon, pulp and cotton may be used. Alternatively, a nylon net may be used.

【0017】含水ゲル層16及び粘着剤層14は、剥離
しやすいようにエンボス処理又はシリコン塗工したポリ
エステルフィルムの剥離フィルム20で覆われている。
The hydrous gel layer 16 and the pressure-sensitive adhesive layer 14 are covered with a release film 20 of a polyester film which is embossed or coated with silicon so as to be easily peeled off.

【0018】含水ゲル層16には、殺菌消毒剤として、
アクリノール、グルコン酸クロルヘキシジン、セチルピ
リジウム、エチルアルコール、イソプロパノール、塩化
ベンザルコニウム、マレイン酸クロルフェニラミン等が
配合されている。さらに、局所麻酔剤として、リドカイ
ン、皮膚修復剤としてアラントイン等の薬剤を配合して
も良い。
The water-containing gel layer 16 has a sterilizing and disinfecting agent.
Acrinol, chlorhexidine gluconate, cetylpyridinium, ethyl alcohol, isopropanol, benzalkonium chloride, chlorpheniramine maleate, etc. are added. Further, a drug such as lidocaine as a local anesthetic and an allantoin as a skin repair agent may be blended.

【0019】さらに、含水ゲル層16には、保湿剤とし
て、グリセリン、イソプロピルアルコール、エチレング
リコール、ポリプロピレングリコール、ポリエチレング
リコール、1,3−ブチレングリコール、その他のポリ
グリセリン等を用いることができる。保湿剤の配合量
は、含水ゲル層16の重量に対して0.1〜10%程
度、好ましくは0.5〜5%である。
Furthermore, glycerin, isopropyl alcohol, ethylene glycol, polypropylene glycol, polyethylene glycol, 1,3-butylene glycol, other polyglycerin and the like can be used as a moisturizing agent in the hydrous gel layer 16. The blending amount of the moisturizer is about 0.1 to 10%, preferably 0.5 to 5% with respect to the weight of the hydrous gel layer 16.

【0020】この実施形態の含水ゲル層16には、有機
塩類、油分、界面活性剤、無機粉体、無機塩類、防腐
剤、pH調整剤、顔料、香料、その他薬効成分などをそ
の使用目的に応じて用いることができる。
In the hydrogel layer 16 of this embodiment, organic salts, oils, surfactants, inorganic powders, inorganic salts, preservatives, pH adjusters, pigments, fragrances, other medicinal ingredients, etc. are used. It can be used accordingly.

【0021】次に、この実施形態の創傷保護剤10の製
造方法について説明する。まず、含水ゲル層16の形成
は、所定の薄い型内に水溶性高分子溶液を加熱して流し
込み、その溶液がゲル化する前に、不織布等のゲル支持
体18をこの水溶性高分子溶液表面に被せ、ゲル支持体
18中にその溶液を染みこませ、ゲル化させる。また
は、大型の不織布等の支持体形性材料の表面に水溶性高
分子溶液を流し、ゲル化させ、この後、所定形状に含水
ゲル層16及びゲル支持体18とも切断しても良い。こ
の場合、任意の大きさの含水ゲル層16を得ることがで
きる。
Next, a method for manufacturing the wound protection agent 10 of this embodiment will be described. First, the water-containing gel layer 16 is formed by heating and pouring a water-soluble polymer solution into a predetermined thin mold, and before the solution is gelled, the gel support 18 such as a nonwoven fabric is placed on the water-soluble polymer solution. The surface is covered, and the solution is impregnated into the gel support 18 and gelled. Alternatively, the water-soluble polymer solution may be poured onto the surface of a support-shaped material such as a large-sized non-woven fabric to cause gelation, and then the hydrous gel layer 16 and the gel support 18 may be cut into a predetermined shape. In this case, the hydrogel layer 16 having an arbitrary size can be obtained.

【0022】含水ゲル層16がゲル化した後、所定形状
のゲル支持体18を粘着剤層14の中央部に貼り付け
る。そして、剥離フィルム20を粘着剤層14及び含水
ゲル層18表面に貼り付け、密封して包装する。
After the hydrous gel layer 16 has gelled, a gel support 18 having a predetermined shape is attached to the central portion of the adhesive layer 14. Then, the release film 20 is attached to the surfaces of the pressure-sensitive adhesive layer 14 and the hydrogel layer 18, sealed and packaged.

【0023】この実施形態の創傷保護剤とその製造方法
によれば、皮膚の創傷面に含水ゲル層16が接触するの
で、細胞の増殖を妨害することなく自然治癒を早めるこ
とができる。また、含水ゲル層16の表面は、滑らかで
柔軟性があるため、凹凸の創傷面にも密着することがで
き、ゲル内の薬剤が均一に創傷部位に作用し、細菌の侵
入も確実に阻止する。含水ゲル層16は、創傷部位に癒
着することが無く、治癒が早く、創傷保護剤の交換時に
も疼痛がない。また、ゲル支持体18が通気性を有する
ので、含水ゲル層16からの水分の蒸発による気化熱に
より、患部を冷却することができる。さらに、粘着剤支
持材12を織布や不織布で構成した場合、含水ゲル層か
らの水分蒸発を促進し、創傷面の冷却効果が高い。ま
た、含水ゲル層16を備えたパッド部15を手で押圧す
ることにより、容易に含水ゲル層16のゲルが破壊し
て、ゲルの溶液を分離するので、ゲル中の薬剤が創傷面
に浸透しやすい。
According to the wound protector of this embodiment and the method for producing the same, since the hydrous gel layer 16 comes into contact with the wound surface of the skin, spontaneous healing can be accelerated without interfering with cell proliferation. In addition, since the surface of the hydrous gel layer 16 is smooth and flexible, it can adhere even to the uneven wound surface, the drug in the gel acts uniformly on the wound site, and the invasion of bacteria is surely blocked. To do. The water-containing gel layer 16 does not adhere to the wound site, heals quickly, and has no pain even when the wound protection agent is replaced. Further, since the gel support 18 has air permeability, the affected area can be cooled by the heat of vaporization due to the evaporation of water from the hydrous gel layer 16. Further, when the pressure-sensitive adhesive support material 12 is made of a woven fabric or a non-woven fabric, it promotes the evaporation of water from the hydrogel layer and has a high effect of cooling the wound surface. Also, by pressing the pad portion 15 provided with the hydrous gel layer 16 with a hand, the gel of the hydrous gel layer 16 is easily broken and the gel solution is separated, so that the drug in the gel penetrates into the wound surface. It's easy to do.

【0024】次にこの発明の第二実施形態について説明
する。この実施形態の創傷保護剤24は、含水ゲル層1
6が薄いCPPのフィルム容器26内に収容され、粘着
剤層14もこのフィルム容器26のフィルムの延長部2
8により被覆されているものである。
Next, a second embodiment of the present invention will be described. The wound protection agent 24 of this embodiment is the water-containing gel layer 1
6 is housed in a thin CPP film container 26, and the adhesive layer 14 is also a film extension 2 of this film container 26.
It is covered with No. 8.

【0025】この実施形態の創傷保護剤24の製造方法
は、まず、フィルム容器26内に上記と同様の水溶性高
分子溶液を流し込み、ゲル化する前に不織布等のゲル支
持体18をフィルム容器24の開口部に被せ、水溶性高
分子溶液をゲル支持体18に染みこませる。この後冷却
して、含水ゲル層16が形成され、このゲル支持体18
及びフィルム容器26の延長部28に粘着剤支持材12
の粘着剤層14を貼り付ける。この後、密封して包装す
る。
In the method of manufacturing the wound protection agent 24 of this embodiment, first, the same water-soluble polymer solution as described above is poured into the film container 26, and the gel support 18 such as a nonwoven fabric is placed in the film container 26 before gelation. The gel support 18 is impregnated with the water-soluble polymer solution by covering the opening of 24. After that, cooling is performed to form the hydrous gel layer 16, and the gel support 18 is formed.
And the adhesive support material 12 on the extension 28 of the film container 26.
Adhesive layer 14 is attached. After this, it is sealed and packaged.

【0026】この実施形態によっても上記と同様の効果
を得ることができ、さらに、含水ゲル層16を包装後も
型くずれ等しないように保護する。
According to this embodiment, the same effect as described above can be obtained, and the hydrous gel layer 16 is protected so as not to lose its shape even after being packaged.

【0027】なお、この発明の創傷保護剤とその製造方
法は上記各実施形態に限定されるものではなく、粘着剤
支持材は、穴あき樹脂フィルムや薄い布や不織布等でも
良い。また、含水ゲル層の形状は適宜設定可能なもので
ある。含水ゲル層への殺菌消毒剤やその他の薬剤の配合
は、溶解させる以外に、乳化や分散させるものでも良
い。
The wound protective agent and the method for producing the same of the present invention are not limited to the above embodiments, and the adhesive support material may be a perforated resin film, a thin cloth, a non-woven cloth or the like. The shape of the hydrous gel layer can be set as appropriate. The sterilizing / disinfecting agent and other chemicals may be added to the water-containing gel layer by emulsification or dispersion in addition to dissolution.

【0028】[0028]

【実施例】以下、この発明の第一実施例の創傷保護剤に
ついて説明する。この実施例では、寒天1.5部を精製
水97.3に混ぜて加熱溶解し、90℃で保温しながら
グリセンリン1部、アクリノール0.2部を順次混合し
溶解する。この溶液2.225gを50mm×45m
m、深さ1mmの樹脂製容器に滴下して容器内に液を充
填する。そして、溶液がゲル化する前に、53mm×4
8mmに裁断した目付100g/mのポリプロピレン
不織布を容器開口部に載せて、不織布に溶液を染みこま
せ、溶液を冷却固化させ、不織布と含水ゲル層を一体化
する。ゲル化した後、含水ゲル層と一体化した不織布を
樹脂製容器から分離し、不織布面を粘着テープに貼着し
て、粘着面及び含水ゲル層に、シリコン塗工したポリエ
ステルフィルムを貼り付け、密封包装する。
EXAMPLES The wound protection agent of the first example of the present invention will be described below. In this example, 1.5 parts of agar was mixed with 97.3 of purified water and dissolved by heating, and 1 part of glycerin and 0.2 part of acrinol were sequentially mixed and dissolved while keeping the temperature at 90 ° C. 2.225 g of this solution is added to 50 mm × 45 m
m and the depth is 1 mm, and the liquid is filled into the container by dropping into a resin container. And before the solution gels, 53 mm x 4
A polypropylene non-woven fabric having a basis weight of 100 g / m 2 cut into 8 mm is placed on the container opening, the non-woven fabric is impregnated with the solution, and the solution is cooled and solidified to integrate the non-woven fabric and the hydrogel layer. After gelling, the non-woven fabric integrated with the hydrous gel layer is separated from the resin container, the non-woven fabric surface is attached to an adhesive tape, the adhesive surface and the hydrous gel layer, a silicone-coated polyester film is attached, Pack tightly.

【0029】次に、この発明の第二実施例の創傷保護剤
について説明する。この実施例では、寒天1.5部を精
製水82.1部に混ぜて加熱溶解し、90℃で保温しな
がら、エチルアルコール15部に塩化ベンザルコニウム
0.1部、塩酸リドカイン1部、塩酸ナファゾリン0.
1部、及びマレイン酸クロルフェニラミン0.2部を溶
解した溶液を分散し混合する。この溶液0.3gを、2
0mm×14mm、深さ1mmの凹部を有し凹部側の表
面にシリコン塗工したCPP樹脂フィルム製の容器内に
滴下し、容器に溶液を充填する。そして、溶液がゲル化
する前に、溶液面に22mm×16mmに裁断した目付
100g/mのポリプロピレン不織布を容器開口部に
載せて、不織布に溶液が染みこむようにし、溶液を冷却
固化させ、不織布と含水ゲル層を一体化する。ゲル化し
た後、不織布が表面に露出したフィルム容器及びその延
長部分に、粘着テープを貼り付けて密封包装する。
Next, the wound protectant of the second embodiment of the present invention will be explained. In this example, 1.5 parts of agar was dissolved in 82.1 parts of purified water by heating and dissolved, and 15 parts of ethyl alcohol, 0.1 part of benzalkonium chloride, and 1 part of lidocaine hydrochloride were dissolved while heating at 90 ° C. Naphazoline hydrochloride 0.
A solution in which 1 part and 0.2 part of chlorpheniramine maleate are dissolved is dispersed and mixed. 0.3 g of this solution
The solution is dropped into a container made of a CPP resin film having a recess of 0 mm × 14 mm and a depth of 1 mm and having a surface on the recess side coated with silicon, and the container is filled with the solution. Then, before the solution gels, a polypropylene nonwoven fabric having a basis weight of 100 g / m 2 cut into 22 mm × 16 mm is placed on the container opening to allow the solution to soak into the nonwoven fabric, and the solution is cooled and solidified, Integrate the non-woven fabric and the hydrogel layer. After the gelation, an adhesive tape is attached to the film container where the non-woven fabric is exposed on the surface and its extension, and the package is hermetically packaged.

【0030】[0030]

【発明の効果】この発明の創傷保護剤とその製造方法に
よれば、簡単な装置で安価に創傷保護剤を製造すること
ができる。そして、皮膚の創傷面に含水ゲル層が接触す
るので、ガーゼ等の絆創膏と比較して細胞の増殖を妨害
することなく自然治癒を早めることができる。また、含
水ゲル層の表面は、滑らかで柔軟性があるため、創傷面
を痛めることなく凹凸の創傷面にも密着することがで
き、ゲル内の薬剤が均一に創傷部位に作用し、細菌の侵
入も確実に阻止する。さらに、含水ゲル層は創傷部位に
癒着することが無く、治癒が早く、創傷保護剤の交換時
にも疼痛がない。さらに、含水ゲル層からの水分の蒸発
による気化熱により、患部を冷却することができる。
According to the wound protectant and the method for producing the same of the present invention, it is possible to inexpensively produce a wound protectant with a simple apparatus. Since the hydrous gel layer comes into contact with the wound surface of the skin, spontaneous healing can be accelerated without interfering with the proliferation of cells as compared with a plaster such as gauze. In addition, since the surface of the hydrogel layer is smooth and flexible, it can adhere to the uneven wound surface without damaging the wound surface, and the drug in the gel acts uniformly on the wound site to prevent bacterial It surely blocks intrusion. Furthermore, the water-containing gel layer does not adhere to the wound site, heals quickly, and there is no pain when the wound protectant is replaced. Furthermore, the affected area can be cooled by the heat of vaporization due to the evaporation of water from the hydrogel layer.

【図面の簡単な説明】[Brief description of drawings]

【図1】この発明の第一実施形態の創傷保護剤平面図で
ある。
FIG. 1 is a plan view of a wound protection agent according to a first embodiment of the present invention.

【図2】この実施形態の創傷保護剤の断面図である。FIG. 2 is a cross-sectional view of the wound protection agent of this embodiment.

【図3】この発明の第二実施形態の創傷保護剤の断面図
である。
FIG. 3 is a cross-sectional view of the wound protection agent according to the second embodiment of the present invention.

【符号の説明】[Explanation of symbols]

10 創傷保護剤 12 粘着剤支持材 14 粘着剤層 15 パッド部 16 含水ゲル層 18 ゲル支持体 20 剥離フィルム 10 Wound protector 12 Adhesive support material 14 Adhesive layer 15 Pad part 16 Hydrous gel layer 18 gel support 20 Release film

───────────────────────────────────────────────────── フロントページの続き (51)Int.Cl.7 識別記号 FI テーマコート゛(参考) A61K 47/36 A61K 47/36 47/42 47/42 47/46 47/46 A61P 17/02 A61P 17/02 Fターム(参考) 4C076 AA74 AA77 BB31 CC19 DD38 EE06P EE16P EE30P EE36P EE38P EE42P EE58P FF31 FF36 GG11 4C206 AA01 CA03 MA02 MA03 MA05 MA11 MA28 MA29 MA52 MA83 NA03 NA12 ZA90 ─────────────────────────────────────────────────── ─── Continuation of front page (51) Int.Cl. 7 Identification code FI theme code (reference) A61K 47/36 A61K 47/36 47/42 47/42 47/46 47/46 A61P 17/02 A61P 17 / 02 F term (reference) 4C076 AA74 AA77 BB31 CC19 DD38 EE06P EE16P EE30P EE36P EE38P EE42P EE58P FF31 FF36 GG11 4C206 AA01 CA03 MA02 MA03 MA05 MA11 MA28 MA29 MA52 MA83 NA03 NA12 ZA90

Claims (11)

【特許請求の範囲】[Claims] 【請求項1】 パッド部に殺菌消毒剤を溶解した含水
ゲル層を有することを特徴とする創傷保護剤。
1. A wound protection agent having a hydrogel layer in which a bactericidal disinfectant is dissolved in a pad portion.
【請求項2】 上記含水ゲル層に、エチルアルコール
を含むことを特徴とする請求項1記載の創傷保護剤。
2. The wound protectant according to claim 1, wherein the hydrogel layer contains ethyl alcohol.
【請求項3】 上記含水ゲル層はゲル支持体に保持さ
れ、このゲル支持体は粘着剤支持材に保持されており、
上記含水ゲル層、ゲル支持体、粘着剤支持材はいずれも
透明であることを特徴とする請求項1または2記載の創
傷保護剤。
3. The hydrous gel layer is held by a gel support, and the gel support is held by a pressure sensitive adhesive support,
The wound protector according to claim 1 or 2, wherein the hydrous gel layer, the gel support, and the adhesive support material are all transparent.
【請求項4】 上記含水ゲル層は、加熱して溶解し、
冷却により固化する水溶性高分子材料から成ることを特
徴とする請求項1,2または3記載の創傷保護剤。
4. The hydrogel layer is heated to dissolve,
The wound protection agent according to claim 1, wherein the wound protection agent is made of a water-soluble polymer material that solidifies by cooling.
【請求項5】 上記水溶性高分子材料は、マンナン、
寒天、ゼラチン、ジェランガム、ポリビニルピロリド
ン、アラビアゴム、またはトラガントゴムから選ばれた
一または複数の材料から成ることを特徴とする請求項4
記載の創傷保護剤。
5. The water-soluble polymer material is mannan,
5. A material or materials selected from agar, gelatin, gellan gum, polyvinylpyrrolidone, gum arabic, and gum tragacanth.
The wound protection agent described.
【請求項6】 上記含水ゲル層は、化学反応により固
化する水溶性高分子材料から成ることを特徴とする請求
項1,2または3記載の創傷保護剤。
6. The wound protector according to claim 1, wherein the hydrous gel layer is made of a water-soluble polymer material that is solidified by a chemical reaction.
【請求項7】 上記水溶性高分子材料は、アルギン酸
ナトリウム、またはポリビニルアルコールを含む合成高
分子であることを特徴とする請求項6記載の創傷保護
剤。
7. The wound protector according to claim 6, wherein the water-soluble polymer material is a synthetic polymer containing sodium alginate or polyvinyl alcohol.
【請求項8】 上記ゲル支持体は、不織布、織布、ま
たはナイロンネットであることを特徴とする請求項1,
2,3,4,5,6または7記載の創傷保護剤。
8. The gel support is a non-woven fabric, a woven fabric, or a nylon net.
The wound protection agent according to 2, 3, 4, 5, 6 or 7.
【請求項9】 上記含水ゲル層は、樹脂フィルムで成
形した浅い容器内に設けられていることを特徴とする請
求項1,2,3,4,5,6,7または8記載の創傷保
護剤。
9. The wound protection according to claim 1, 2, 3, 4, 5, 6, 7 or 8, wherein the hydrogel layer is provided in a shallow container formed of a resin film. Agent.
【請求項10】 含水ゲルを構成する水溶性高分子溶
液を、ゲル支持体の片面に部分的に吸着浸透させ、ゲル
化後、上記ゲル支持体を粘着剤支持材の粘着剤層に貼り
付けることを特徴とする創傷保護剤の製造方法。
10. A water-soluble polymer solution constituting a hydrogel is partially adsorbed and permeated on one side of a gel support, and after gelation, the gel support is attached to an adhesive layer of an adhesive support material. A method for producing a wound protection agent, comprising:
【請求項11】 上記含水ゲル層をシート状の上記ゲ
ル支持体上に一体に形成し、打ち抜きにより所定の大き
さに形成し、このゲル支持体を粘着剤支持材の粘着剤層
に貼付することを特徴とする請求項10記載の創傷保護
剤の製造方法。
11. The water-containing gel layer is integrally formed on the sheet-like gel support, punched to a predetermined size, and the gel support is attached to the pressure-sensitive adhesive layer of the pressure-sensitive adhesive support material. The method for producing the wound protection agent according to claim 10, which is characterized in that.
JP2001400101A 2001-12-28 2001-12-28 Method for producing wound dressing Expired - Lifetime JP3973420B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2001400101A JP3973420B2 (en) 2001-12-28 2001-12-28 Method for producing wound dressing

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2001400101A JP3973420B2 (en) 2001-12-28 2001-12-28 Method for producing wound dressing

Publications (2)

Publication Number Publication Date
JP2003190206A true JP2003190206A (en) 2003-07-08
JP3973420B2 JP3973420B2 (en) 2007-09-12

Family

ID=27604844

Family Applications (1)

Application Number Title Priority Date Filing Date
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Country Status (1)

Country Link
JP (1) JP3973420B2 (en)

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US9084695B2 (en) 2008-12-25 2015-07-21 Hisamitsu Pharmaceutical Co., Inc. Pressure-sensitive adhesive tape package
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WO2018135813A1 (en) * 2017-01-19 2018-07-26 최성현 Pad for alleviating and treating plasma protein exudation skin diseases including atopic diseases
CN113288587A (en) * 2021-07-28 2021-08-24 南通跃香拉链有限公司 Outdoor first aid is with stanching bandage

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