JP2003073245A - Composition for oral cavity - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a dentifrice composition which scarcely damages and abrades dentin and has a high stain-removing effect. SOLUTION: This dentifrice composition contains 0.5 to 5 wt.% of an alkyl glycoside having an alkyl chain length having 8 to 16C carbon atoms and 10 to 30 wt.% of precipitated silica having a weight-average particle size of 9 to 13 μm, oil absorption of 90 to 130 cc/100 g, and a RDA value of <=70, has a total RDA value of >=50, scarcely damages and abrades dentin, and has a high stain-removing effect.

Description

Description: BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a dentifrice composition having a high stain-removing effect with reduced damage and abrasion of dentin. [0002] Stain is a pigmentation on the tooth surface which is thought to be caused by ingredients in food, and is a major aesthetic problem. In order to remove the stain, an ordinary dentifrice composition contains an abrasive, and it is generally said that the use of an abrasive having a high abrasive power has a large stain removing effect. However, when the gums regress due to periodontal disease or excessive brushing, the dentin at the root of the teeth is exposed, but the dentin is more easily worn than the enamel, so if a dentifrice composition having a normal abrasive power or more is used. It is not preferable because dentin is worn away. Until now, Japanese Patent Application Laid-Open No. 11-508533 and Japanese Patent Application Laid-Open No. 11-508533 have disclosed abrasives and dentifrices which have attempted to maintain a low abrasive power and a high stain removing power.
Japanese Patent Application Laid-Open Nos. 504918 and 11-504919 have been proposed, but none of them has sufficiently low polishing power and sufficient stain removal power. Also, JP-A-1-125315, JP-A-2-56413, JP-A-5-163126, and JP-A-10-17
Although the composition proposed in, for example, Japanese Patent No. 443 inhibits the formation of stain, the effect of removing stain already deposited on teeth is small. [0003] An object of the present invention is to provide a dentifrice composition which has a high stain removal effect while suppressing damage and abrasion of dentin. [0004] The alkyl chain length is 8 carbon atoms
0.5 to 5% by weight of an alkylglucoside having an oil absorption of 90 to 13 μm and an oil absorption of 90 to 13 μm.
A dentifrice composition containing 130 cc / 100 g of precipitated silica having an RDA value of 70 or less and having an RDA value of 70 or less, and an RDA value of the whole composition of 50 or less suppresses damage and abrasion of dentin to a low level, And it was found that the stain removing effect was high. DETAILED DESCRIPTION OF THE INVENTION The alkyl glycoside used in the present invention has an alkyl chain length of 8 to 16 carbon atoms. When the carbon number of the alkyl chain length is shorter than 8, bitterness is produced, and when the carbon number is longer than 16, the foaming property is reduced, so that the use as an oral composition may become difficult. The amount of alkyl glucoside is preferably 0.5 to 5% by weight. If the amount is less than 0.5% by weight, the foamability of the oral composition becomes small, and the feeling upon use is reduced. If it is more than 5% by weight, the taste and odor derived from the alkyl glucoside cannot be ignored, which is not preferable. The precipitated silica used in the present invention has a weight average particle size of 9 to 13 μm and an oil absorption of 90 to 130 cc / 100.
g, RDA value is 70 or less, and 5 to 30% by weight can be blended. In order to avoid the risk of dentin abrasion, the RDA value of the entire composition is set to 50 or less in order to avoid the risk of dentin abrasion, and this RDA value can be adjusted by the amount of precipitated silica. [0007] The oral composition of the present invention comprises toothpaste, lubricating toothpaste, liquid dentifrice, oral pasta, mouth freshener, spray,
It can be prepared into a dosage form such as foam. The oral composition according to the present invention, due to the difference in their dosage form, appropriate components according to their type, for example, active ingredients, wetting agents, binders,
Appropriate components such as preservatives, flavoring agents, surfactants, and pH adjusters can be blended within a range that does not impair the effects of the present invention. The active ingredients include cationic bactericides such as quaternary ammonium salts and biguanides, nonionic bactericides such as triclosan and isopropylmethylphenol, sodium fluoride, tin fluoride and sodium monofluorophosphate. And enzymes such as amylase, protease, lysozyme and dextranase, and vitamins such as vitamins B, C and E. Examples of the binder include cellulose derivatives such as sodium carboxymethylcellulose, carboxymethylhydroxyethylcellulose, hydroxyethylcellulose and hydroxypropylcellulose, xanthan gum,
Gums such as tragacanth gum, karaya gum, arabia gum, carrageenan, and O- [2-hydroxy-3-chloride;
(Trimethylammonio) propyl] hydroxyethylcellulose and the like. The humectant includes glycerin, propylene glycol, sorbitol, polyethylene glycol, xylitol and the like. Examples of the preservative include methyl paraben, propyl paraben, benzoate, sodium benzoate and the like. [0012] Flavoring agents include saccharin sodium, acesulfame potassium, stevioside, neohesperidyl dihydrochalcone, glycyrrhizin, perillartin, thaumatin, asparatyl phenylalanyl methyl ester, xylitol, palatinose, reduced palatinose, menthol, spearmint oil, peppermint oil oil,
Examples include lemon oil, orange oil, sage oil, rosemary oil, cinnamon oil, perilla oil, winter green oil, clove oil, eucalyptus oil, eugenol, and plum oil. Surfactants can be added in addition to the above-mentioned alkyl glucosides as long as the effect is not impaired.
Surfactants other than alkyl glucosides include sodium lauryl sulfate, alkyl sulfates such as sodium myristyl sulfate, acyl sarcosinates such as sodium lauroyl sarcosinate, sodium myristril sarcosine, acyl glutamate, palmitoyl glutamate, N- Acyl amino acid salts such as methyl-N-acyltaurine salts and N-methyl-N-acylalanine salts;
Anionic surfactants such as coconut fatty acid monoglyceride monosulfate, lauryl sulfoacetate, α-olefin sulfonate, sugar fatty acid esters such as sucrose fatty acid ester, maltose fatty acid ester and lactose fatty acid ester, maltitol fatty acid ester, lactitol Fatty acid esters such as sugar alcohol fatty acid esters, polyoxyethylene sorbitan monolaurate, polyoxyethylene sorbitan fatty acid esters such as polyoxyethylene sorbitan monostearate, polyoxyethylene fatty acid esters such as polyoxyethylene glycol laurate, and lauric acid Mono- or di-
Ethanolamide, myristic acid mono- or di-
Fatty acid diethanolamide such as ethanolamide, polyoxyethylene polyoxypropylene copolymer, polyoxyethylene polyoxypropylene fatty acid ester,
Nonionic surfactants such as polyoxyethylene hydrogenated castor oil, polyglycerin fatty acid esters, and N
-Amphoteric surfactants such as betaine-type surfactants such as N-alkyldiaminoethylglycine such as lauryldiaminoethylglycine and N-myristyldiaminoethylglycine, fatty acid amidopropyl betaine, alkylbetaine imidazolinium betaine and alkylsulfobetaine; No. [0014] pH adjusters include citric acid and its salts, phosphoric acid and its salts, malic acid and its salts, gluconic acid and its salts, maleic acid and its salts, aspartic acid and its salts, gluconic acid and its salts Succinic acid and its salts, glucuronic acid and its salts, fumaric acid and its salts, glutamic acid and its salts, adipic acid and its salts, hydrochloric acid, sodium hydroxide, potassium hydroxide, and sodium silicate. The present invention will be described in more detail with reference to the following Examples, but it should not be construed that the present invention is limited to these Examples. Unless otherwise specified,% in Examples is% by weight. Each component was mixed in the mixing ratio shown in Table 1,
A dentifrice composition was obtained by a conventional method. [Table 1] When the RDA value and the stain removal power of the oral compositions of Examples 1 and 2 and Comparative Examples 1 to 4 were evaluated by the following methods, Examples 1 and 2 were as shown in the table. 4, the RDA value was lower and the stain removal power was higher. RDA test: Hefferr et al.
n et al., Journal of Dental Research, 55, 563-73,
RDA (Radioacti) based on the method described in
ve Dentine Abrasion) value.
This method is an authorized method for measuring the polishing amount of a dentifrice or an abrasive, and detailed procedures and the like are described in JP-A-62-87507.
In the case of a general dentifrice, the RDA value is in the range of about 60 to 120. Stain removal test: The stain removal power of dentifrices and abrasives was determined by the paper by Stooky et al.,
Journal of Dental Research, 61, 1236-39, 1982). The method is described below.
A 4 mm square piece of an enamel specimen of beef permanent teeth (incisor teeth) was cut out squarely, fitted into a transparent polyester resin, the specimen surface was smoothed, and mirror-polished using kaolin. The sample surface was immersed in 0.2 mol / L hydrochloric acid for 60 seconds, then immersed in a saturated aqueous solution of sodium carbonate for 30 seconds, immersed in a 1% aqueous solution of phytic acid for 60 seconds, and then washed with ion-exchanged water. The stain medium contains 1.02 g of instant coffee, 1.02 g of instant tea, 0.75 g
g of swine stomach mucin, pigment-producing bacterium (Micrococcus luteus) 24
A 50-mL culture solution was prepared by adding 50 mL to a sterilized Trypticase Soy medium (250 mL). Sample and stain medium 37
The sample was set in a thermostat at 10 ° C. for 10 days. 0.03 on day 11
g Iron (III) chloride hexahydrate was added and the medium was changed every day until L * was 32-35. After that, the specimen was taken out, washed carefully with ion-exchanged water, used as a sample for measurement, and used as a baseline for a spectrophotometer (Minolt
a), L * 1, a * 1, and b * 1 were measured. The sample was set on a brushing machine equipped with a commercially available toothbrush (nylon bristles), and reciprocated 800 times at a pressure of 150 g in 75 mL of the three-fold diluted slurry of Examples 1-2 and Comparative Examples 1-2. The sample dried for 1 hour was measured for L * 2, a * 2, and b * 2 using a spectrophotometer (Minolta). Further, L * 3, a * 3, and b * 3 were measured on the sample from which the remaining stain was removed with a dental handpiece. The stain removal (%) was obtained by substituting into the following equation. ## EQU1 ## According to the present invention, it has been possible to provide a dentifrice composition having a high stain removing effect while suppressing damage and abrasion of dentin.

Claims (1)

1. An alkyl glucoside having an alkyl chain length of 8 to 16 carbon atoms in an amount of 0.5 to 5% by weight, a weight average particle size of 9 to 13 μm, and an oil absorption of 90 to 130 cc / 1.
1 g of precipitated silica having an RDA value of 70 g or less
A dentifrice composition containing 0 to 30% by weight and having an RDA value of 50 or less in the whole composition