JP2002531333A - Packaging means for drugs in the form of a folding box combination for at least two different primary packs - Google Patents

Abstract

SUMMARY OF THE INVENTION The present invention is directed to a drug in the form of a cardboard folding box that contains both drugs, in the form of a folding box combination for at least two different primary packagings including a transdermal plaster and a capsule. Packaging means. The aforementioned folding boxes include containers for individual rectangular plasters stacked in bulk in containers. Said container has a front wall (1) and a rear wall (2) with a folding lid (6), a folding bottom (5) and a joint (26-30) for a transverse wall (3, 4). It has a structure according to DIN 55 429. The packaging means according to the invention is characterized in that the folding box further comprises a perforated unfinished part (12) joined on both sides of the push-in slot (11) formed therebetween by joining (10, 10 ') to the front wall (1). ). The aforementioned perforated blank part (12) has two flat parts (14, 15) that can be folded on top of each other along a fold line (13). Many holes (16, 17) are located in the aforementioned flat part. The perforated unfinished part is configured to accommodate a tablet blister unit having a deep drawn tablet cup containing a capsule. The aforementioned tablet blister unit can be inserted between the flat parts (14, 15).

Description

DETAILED DESCRIPTION OF THE INVENTION

In certain cases, this involves both the oral ingestion of active ingredient-containing capsules and simultaneously the slow action therapy by systemic delivery of the active ingredient through the skin using a transdermal therapeutic system in the form of a self-adhesive plaster. For indications of disease states or conditions that require or suggest combination therapy, to date, drugs of different shapes and sizes-capsules and transdermal plasters (TTS)-have been offered for sale, usually with different shapes and sizes. In practice, the primary packs of the foldable boxes were individually wrapped in secondary packs.

[0002] This often has the disadvantageous consequence of not using them at the same time or misplacing or forgetting one of the drugs. However, in each case, storage and use problems have arisen due to the individual packaging, especially for patients at home. Thus, there is a need or requirement, in particular, to actually contain two different forms of a drug in a packaging combination that cannot be combined and separated, in order to ensure that they are always used correctly.

[0003] Accordingly, it is an object of the present invention to provide for the storage of two different primary packs of different drugs which are nevertheless provided for use together, so that the folding box combination can be molded, handled and produced. The aim is to design a packaging means in the form of a folding box combination which is simple from the point of view and can be produced cost-effectively in one piece from a single unfinished product. Sometimes, the folding box combination is also intended to be suitable for accommodating TTS having different surface area dimensions.

In order to achieve this object, the invention proposes, in the case of a packaging means of the kind specified in the preamble of claim 1, to design a combination of folding boxes according to the features of the features of claim 1 I do. Particularly advantageously, a folding box designed according to the invention joins two different primary packs, accommodates them inseparably, and produces cost-effectively from a single cardboard blank. Very well suited for

[0005] Further advantageous shapes of the folding box combination according to the invention can be taken from the features of the dependent claims 2-6. Dependent claims 7 and 8 outline an alternative shape of the folding box combination, wherein the packaging space for the rectangular plaster is suitable for accommodating TTS of different surface area dimensions due to the double wall design. In more detail, the features and advantages of the invention can be taken from the following description of two embodiments, which are schematically illustrated in the drawings.

[0006] FIG. 1 shows a primary box packed together and loose in the form of a folding box combination for at least two different primary packs comprising a transdermal plaster on one side and a capsule on the other side. In the form of a cardboard folding box with space suitable for accommodating individual rectangular plasters that can be placed one on top of the other,
This comprises a DIN 5 having a front wall 1 and a rear wall 2 with insertable covers 6, insertable bases 5 and folding line-shaped nodes 26-30 for the lateral sides 3,4.
Figure 5 shows a plan view of an unfinished product made of a folding box cardboard for manufacturing packaging means for drugs, having a structure according to 5429. On both sides of the insertion slit 11 formed between the aforementioned nodes, the nodes 10, 10 'on the front wall allow the folding box to also rotate relative to each other over the circumference of the folding line 13. It has a perforated blank section 12 having 14, 15 each having a number of holes 16, 17 disposed therein, said perforated blank section comprising a surface area section 14, 1;
It can be located between five and is designed to accommodate a tablet blister pack unit with thermoformed capsule-containing tablet blisters.

[0007] The arrangement of the holes 16, 17 allows the thermoformed blister of the tablet blister pack unit to be inserted therein, so that for removal purposes,
The capsule is selected so that it can be extruded from the tablet blister through the holes 16, 17 by finger pressure, a method known per se. An advantageous shape is that, after the tablet unit is placed in place and the two surface areas 14, 15 are rotated on top of each other, the latter joins together with the aid of an adhesive strip 18 with the aid of an adhesive strip 18 Provide what you can.

Furthermore, the co-rotating surface areas 14, 15 provide for having gripping assistance in the form of recesses 19. Furthermore, the insertion flap 7 is preferably provided with an opening aid in the form of a semicircular recess 20 in the front wall 1. One form provides that on the rear wall 2 the unfinished product of the folding box has an adhesive flap 8 that can be curved around a folding line 25. The aforementioned adhesive flap can be coated with a self-adhesive material or a heat-sealable sealing medium.

After folding the front wall 1, the rear wall 2 and the lateral sides 3, 4 into position, the adhesive flap 8 is adhesively bonded or sealed to the lateral side 3, and the cubic object is Can be formed in the process. Next, the support flaps 23, 23
'And 24, 24' are replaced by folding lines 21, 21 'and 22, 22, respectively.
Curve inwardly around the 'by 90 ° towards the inside of the cube, acting as a support for the surface areas 5 and 12 to be folded later.

Prior to this, the tablet blister pack unit is inserted into the surface region 14 or 1
5, the form of the blister protrudes through the holes 16 or 17, whereby the surface area 15 is folded 180 ° around the fold line 13 and is located above the surface area 14 and the adhesive strip 18 with the aid of 18
And thereby rotate in the direction of the opening of the cube obtained below the insertable cover 6. The insertable cover 6 arranged thereon is then engaged in this part by the insertion flap 7 with the insertion slit 11. On the other side,
The insertable base 5 rotates; this engages in the slit formed by the insertion flap 9 between the uppermost end of the rear wall 2 and the rotary support flaps 23, 24,
Folding box combination 1 is closed in the process.

[0011] Naturally, the rectangular TTS plaster already preliminarily wrapped in the front wall 1, the rear wall 2
And in the cubic recess formed between the lateral sides 3,4. The folding box
Completed in this way; as a secondary pack, it contains, on one side, a tablet blister pack unit with thermoformed capsule-containing tablet blisters and, on the other side, a stack of rectangular TTS plasters.

The unfinished product of FIG. 2 differs from the unfinished product of FIG.
Instead of ', 24', the double-walled surface area elements 40, 40 'are assigned by double fold lines 21', 21 "; 22 ', 22". The distal adhesive tabs 42, 42 'are provided with the fold lines 41, 41.
', Instead of the support flaps 23, 24, the lateral surfaces 3,
4 differs in that wing tabs 43, 44 are provided at the opposite ends, which can be joined by fold lines 21, 22 and have a surface area equal to the adhesive tabs 42, 42 '.

When assembling the resulting folding box combination by folding, first the surface region 40 is folded 180 ° parallel to the lateral sides 3, 4 through the double folding lines 21, 21 ″ and at the same time 90 times ° Adhesive tab 42 that is folded inward,
43 are adhesively connected to each other. Similarly, double folding line 22 '
, 22 "and the adhesive tabs 44, 42 'bonded adhesively form a double wall on each lateral side. The rest of the unfinished product is folded in place to obtain a folding box cube in the same way as for the unfinished product of FIG. 1, and the adhesive flap 8 is adhesively bonded to the lateral side surface 3; Next, the tablet blister pack unit is inserted into the surface area 1
4, 15 which are adhesively bonded to each other by an adhesive strip 18, curved 180 ° inwardly around the nodes 10, 10 ', with a rotating insertable cover on the top side. 6, the insertion flap 7 is latched in the insertion slit 11, during which the lower side is inserted on all sides by the insertable base 5.
The latter is folded 180 ° and the flaps are at the top of the rear wall 2 and the fold line 21,
After being inserted into the gap between them, it is closed. The resulting inside of the cube is reduced in size as a result of the double wall and can thus have the effect of accommodating a stack of plasters of a corresponding surface area dimension.

As can be taken from the drawings, the unfinished product of FIGS. 1 and 2 is simple and allows the folding box combination of the present invention to be easily assembled by folding. In this regard, the present invention achieves the objectives set in an optimal manner.

[Brief description of the drawings]

FIG. 1 to accommodate a tablet blister pack having a rectangular form of TTS on one side, a primary-packed TTS plaster and a thermoformed part blister on the other side and tablets covered by aluminum foil. FIG. 6 is a view showing an unfinished product for the folding box combination of FIG.

FIG. 2 shows a folding box blank with similar basic shape but with additional surface area for double wall design on the lateral sides.

[Procedural Amendment] Submission of translation of Article 34 Amendment of the Patent Cooperation Treaty

[Submission date] January 5, 2001 (2001.1.5)

[Procedure amendment 1]

[Document name to be amended] Statement

[Correction target item name] Claims

[Correction method] Change

[Correction contents]

[Claims]

────────────────────────────────────────────────── ─── Continued on the front page (51) Int.Cl. ⁷ Identification symbol FI Theme coat ゛ (Reference) B65D 77/02 B65D 77/02 D 85/82 85/82 [Continuation of summary] It is formed as follows. The aforementioned tablet blister unit can be inserted between the flat parts (14, 15).

Claims (10)

[Claims] 1. The primary packs are housed together and loosely stacked in the form of a folding box combination for at least two different primary packs, comprising a transdermal plaster on one side and a capsule on the other side In the form of a cardboard folding box with a space suitable for accommodating individual rectangular plasters that can be placed in the form of an insertable cover (6), insertable base (5) and lateral sides Front wall (1) and back wall (3) with nodes (26-30) for (3,4)
2) a packaging means for a drug having a structure according to DIN 55 429, comprising a node (1) on the front wall (1) on both sides of an insertion slit (11) formed between said nodes.
0, 10 '), the folding boxes can also be rotated relative to one another around the folding line (13), each having two surface areas in which a number of holes (16, 17) are arranged. A perforated unfinished product part (12) including parts (14, 15);
The perforated blank part can be located between the surface areas (14, 15) and is designed to accommodate a tablet blister pack unit having a thermoformed capsule-containing tablet blister. Said packaging means. 2. After the tablet unit is in place and the two surface areas (14, 15) are rotated on top of each other, the latter is separated by an adhesive strip (18).
2. Packaging means according to claim 1, characterized in that they can be joined together with the aid of (1). 3. The packaging means as claimed in claim 1, wherein the co-rotating surface areas (14, 15) have gripping aids in the form of recesses (19). 4. The insertion flap (7) is provided with opening aids, preferably in the form of semi-circular recesses (20) in the front wall (1).
3. The packaging means according to 1 or 2 or 3 above. 5. The unfinished product of the folding box has, on the rear wall (2), an adhesive flap (8) that can be curved around a folding line (25). Packaging means according to one or more of items 1 to 4. 6. A supporting flap (23, 23 '; 24, 24') which can be rotated by means of a folding line (21, 21 '; 22, 22') on each lateral side (3, 4). The packaging means according to claim 1, wherein the packaging means is provided. 7. Support flaps (23 ', 24') on lateral side surfaces (3, 4).
Instead of a double fold line (21 ′, 21 ″; 22 ′, 22 ″), a double wall forming surface area element (40, 40 ′) is applied, and the fold line (41) is applied to the surface area element. , 41 ′) apply distal adhesive tabs (42, 42 ′) and, instead of the support flaps (23, 24), fold lines (21) at the opposite ends of the lateral surfaces (3, 4). A packaging means according to claim 1, characterized in that there is provided an adhesive tab (43, 44) which can be joined by an adhesive tab (42, 42 ') and which has a surface area equal to that of the adhesive tab (42, 42'). 8. The surface region (40, 40 ′) is folded parallel to the surface region (3, 4) and a double wall (3, 40; 4, 40 ′) is formed in this process. 8. Packaging means according to claim 7, characterized in that, when doing so, the adhesive tabs (43, 44) and the adhesive tabs (42, 42 ') can be adhesively bonded to one another. 9. The insertion flap (9) is arranged on an insertable base (5) by means of a node (26 ') shown as a folding line.
-Packaging means according to one or more of items 8 to 8. 10. The method according to claim 1, wherein the folding box combination can be obtained in a single piece from a cardboard blank that can be assembled by folding and inserting operations. Packaging means as described.