JP2002508338A5 - - Google Patents
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- Publication number
- JP2002508338A5 JP2002508338A5 JP2000538720A JP2000538720A JP2002508338A5 JP 2002508338 A5 JP2002508338 A5 JP 2002508338A5 JP 2000538720 A JP2000538720 A JP 2000538720A JP 2000538720 A JP2000538720 A JP 2000538720A JP 2002508338 A5 JP2002508338 A5 JP 2002508338A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- hiv
- composition according
- lentivirus
- vector
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000008194 pharmaceutical composition Substances 0.000 description 4
- 241000725303 Human immunodeficiency virus Species 0.000 description 3
- 241000713666 Lentivirus Species 0.000 description 2
- 241000713772 Human immunodeficiency virus 1 Species 0.000 description 1
Description
【特許請求の範囲】
【請求項1】 レンチウィルス ベクターを含んで成る、レンチウィルスにより感染された対象を治療するための医薬組成物。
【請求項2】 前記ベクターが、損なわれていない5’LTR (長い末端反復体)を有する請求項1記載の医薬組成物。
【請求項3】 前記レンチウィルスが、ヒト免疫欠損ウィルス(HIV )である請求項1記載の医薬組成物。
【請求項4】 前記HIV が、HIV −1である請求項3記載の医薬組成物。
[Claims]
1. A pharmaceutical composition for treating a subject infected by a lentivirus, comprising a lentiviral vector.
2. The pharmaceutical composition according to claim 1, wherein the vector has an intact 5 ′ LTR (long terminal repeat).
3. The pharmaceutical composition according to claim 1, wherein the lentivirus is a human immunodeficiency virus (HIV).
4. The pharmaceutical composition according to claim 3, wherein the HIV is HIV-1.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US6957997P | 1997-12-12 | 1997-12-12 | |
US60/069,579 | 1997-12-12 | ||
PCT/US1998/025720 WO1999030742A1 (en) | 1997-12-12 | 1998-12-11 | Therapeutic use of lentiviral vectors |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2002508338A JP2002508338A (en) | 2002-03-19 |
JP2002508338A5 true JP2002508338A5 (en) | 2006-01-26 |
Family
ID=22089926
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2000538720A Pending JP2002508338A (en) | 1997-12-12 | 1998-12-11 | Therapeutic use of lentiviral vectors |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP1037669A4 (en) |
JP (1) | JP2002508338A (en) |
KR (1) | KR20010033062A (en) |
AU (1) | AU749059B2 (en) |
CA (1) | CA2314683A1 (en) |
WO (1) | WO1999030742A1 (en) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001030847A1 (en) | 1999-10-22 | 2001-05-03 | Aventis Pasteur Limited | Modified gp100 and uses thereof |
US6656706B2 (en) | 1999-12-23 | 2003-12-02 | The United States Of America As Represented By The Department Of Health And Human Services | Molecular clones with mutated HIV gag/pol, SIV gag and SIV env genes |
AU5810201A (en) | 2000-05-10 | 2001-11-20 | Aventis Pasteur | Immunogenic polypeptides encoded by mage minigenes and uses thereof |
US6712612B1 (en) | 2000-12-12 | 2004-03-30 | Genecure Llc | Safe and stable retroviral helper cell line and related compositions and methods |
US20040225077A1 (en) | 2002-12-30 | 2004-11-11 | Angiotech International Ag | Drug delivery from rapid gelling polymer composition |
JP2006524051A (en) | 2003-04-24 | 2006-10-26 | フォンダッチォーネ・セントロ・サン・ラファエル・デル・モンテ・タボール | Lentiviral vector with bi-directional synthetic promoter and use thereof |
US20120040367A1 (en) | 2007-10-15 | 2012-02-16 | The University Of Queensland | Construct system and uses therefor |
US9795658B2 (en) | 2010-04-20 | 2017-10-24 | Admedus Vaccines Pty Ltd | Expression system for modulating an immune response |
WO2017096432A1 (en) | 2015-12-09 | 2017-06-15 | Admedus Vaccines Pty Ltd | Immunomodulating composition for treatment |
WO2018018082A1 (en) | 2016-07-26 | 2018-02-01 | The Australian National University | Immunostimulatory compositions and uses therefor |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3325579B2 (en) * | 1995-03-16 | 2002-09-17 | 久光製薬株式会社 | New recombinants |
US5650309A (en) * | 1995-05-16 | 1997-07-22 | The Regents Of The University Of California | Viral vectors |
US6013516A (en) * | 1995-10-06 | 2000-01-11 | The Salk Institute For Biological Studies | Vector and method of use for nucleic acid delivery to non-dividing cells |
DE69626681T2 (en) * | 1995-11-28 | 2004-02-12 | The Johns Hopkins University School Of Medicine | CONDITIONAL REPLICATIVE VIRAL VECTORS AND THEIR USE. |
WO1997020052A1 (en) * | 1995-11-28 | 1997-06-05 | Clinical Technologies, Inc. | Recombinant hiv and modified packaging cells and method for treating acquired immune deficiency syndrome |
JP2000517290A (en) * | 1996-02-21 | 2000-12-26 | リスジーウィックス,ジュリアナ | Methods and compositions for protective and therapeutic gene immunization |
AU723313B2 (en) * | 1996-03-05 | 2000-08-24 | Regents Of The University Of California, The | Recombinant live feline immunodeficiency virus and proviral DNA vaccines |
CA2261987C (en) * | 1996-07-22 | 2008-09-30 | The Government Of The United States Of America, Represented By The Secre Tary, Department Of Health And Human Services | Vectors for inhibiting hiv and tumor growth |
JP2001513643A (en) * | 1997-03-06 | 2001-09-04 | ウーベルラ、クラウス | Vectors and vector systems based on lentivirus |
GB9704977D0 (en) * | 1997-03-11 | 1997-04-30 | Univ Glasgow | FIV vaccine |
WO1999004026A2 (en) * | 1997-07-18 | 1999-01-28 | Chiron Corporation | Lentiviral vectors |
-
1998
- 1998-12-11 EP EP98962895A patent/EP1037669A4/en not_active Withdrawn
- 1998-12-11 KR KR1020007006423A patent/KR20010033062A/en not_active Application Discontinuation
- 1998-12-11 CA CA002314683A patent/CA2314683A1/en not_active Abandoned
- 1998-12-11 JP JP2000538720A patent/JP2002508338A/en active Pending
- 1998-12-11 AU AU18035/99A patent/AU749059B2/en not_active Ceased
- 1998-12-11 WO PCT/US1998/025720 patent/WO1999030742A1/en not_active Application Discontinuation
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