EP1037669A4 - Therapeutic use of lentiviral vectors - Google Patents

Therapeutic use of lentiviral vectors

Info

Publication number
EP1037669A4
EP1037669A4 EP98962895A EP98962895A EP1037669A4 EP 1037669 A4 EP1037669 A4 EP 1037669A4 EP 98962895 A EP98962895 A EP 98962895A EP 98962895 A EP98962895 A EP 98962895A EP 1037669 A4 EP1037669 A4 EP 1037669A4
Authority
EP
European Patent Office
Prior art keywords
therapeutic use
lentiviral vectors
lentiviral
vectors
therapeutic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP98962895A
Other languages
German (de)
French (fr)
Other versions
EP1037669A1 (en
Inventor
Luigi Naldini
Jin-Ping Song
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cell Genesys Inc
Original Assignee
Cell Genesys Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cell Genesys Inc filed Critical Cell Genesys Inc
Publication of EP1037669A1 publication Critical patent/EP1037669A1/en
Publication of EP1037669A4 publication Critical patent/EP1037669A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/76Viruses; Subviral particles; Bacteriophages
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
EP98962895A 1997-12-12 1998-12-11 Therapeutic use of lentiviral vectors Withdrawn EP1037669A4 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US6957997P 1997-12-12 1997-12-12
US69579P 1997-12-12
PCT/US1998/025720 WO1999030742A1 (en) 1997-12-12 1998-12-11 Therapeutic use of lentiviral vectors

Publications (2)

Publication Number Publication Date
EP1037669A1 EP1037669A1 (en) 2000-09-27
EP1037669A4 true EP1037669A4 (en) 2003-04-02

Family

ID=22089926

Family Applications (1)

Application Number Title Priority Date Filing Date
EP98962895A Withdrawn EP1037669A4 (en) 1997-12-12 1998-12-11 Therapeutic use of lentiviral vectors

Country Status (6)

Country Link
EP (1) EP1037669A4 (en)
JP (1) JP2002508338A (en)
KR (1) KR20010033062A (en)
AU (1) AU749059B2 (en)
CA (1) CA2314683A1 (en)
WO (1) WO1999030742A1 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4540033B2 (en) 1999-10-22 2010-09-08 サノフィ パストゥール リミテッド Methods for inducing and / or enhancing immune responses against tumor antigens
US6656706B2 (en) 1999-12-23 2003-12-02 The United States Of America As Represented By The Department Of Health And Human Services Molecular clones with mutated HIV gag/pol, SIV gag and SIV env genes
ATE513913T1 (en) 2000-05-10 2011-07-15 Sanofi Pasteur Ltd IMMUNOGENIC POLYPEPTIDES ENCODED BY MAGE MINIGENE AND USES THEREOF
US6712612B1 (en) 2000-12-12 2004-03-30 Genecure Llc Safe and stable retroviral helper cell line and related compositions and methods
WO2004060346A2 (en) 2002-12-30 2004-07-22 Angiotech International Ag Drug delivery from rapid gelling polymer composition
JP2006524051A (en) 2003-04-24 2006-10-26 フォンダッチォーネ・セントロ・サン・ラファエル・デル・モンテ・タボール Lentiviral vector with bi-directional synthetic promoter and use thereof
US9593340B2 (en) 2007-10-15 2017-03-14 Admedus Vaccines Pty Ltd. Expression system for modulating an immune response
US9795658B2 (en) 2010-04-20 2017-10-24 Admedus Vaccines Pty Ltd Expression system for modulating an immune response
JP7110108B2 (en) 2015-12-09 2022-08-01 ジンガン メディスン(オーストラリア) プロプライアタリー リミティド Therapeutic immunomodulatory compositions
WO2018018082A1 (en) 2016-07-26 2018-02-01 The Australian National University Immunostimulatory compositions and uses therefor

Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996028565A1 (en) * 1995-03-16 1996-09-19 Hisamitsu Pharmaceutical Co., Inc. Novel gene recombinant
WO1997012622A1 (en) * 1995-10-06 1997-04-10 The Salk Institute For Biological Studies Vector and method of use for nucleic acid delivery to non-dividing cells
WO1997020060A1 (en) * 1995-11-28 1997-06-05 The Johns Hopkins University School Of Medicine Conditionally replicating viral vectors and their use
WO1997020052A1 (en) * 1995-11-28 1997-06-05 Clinical Technologies, Inc. Recombinant hiv and modified packaging cells and method for treating acquired immune deficiency syndrome
WO1997031119A1 (en) * 1996-02-21 1997-08-28 Res Inst For Genetic And Human Methods and compositions for protective and therapeutic genetic immunization
WO1997032983A1 (en) * 1996-03-05 1997-09-12 The Regents Of The University Of California Recombinant live feline immunodeficiency virus and proviral dna vaccines
WO1998003669A2 (en) * 1996-07-22 1998-01-29 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Vectors for inhibiting hiv and tumor growth
WO1998039463A2 (en) * 1997-03-06 1998-09-11 Ueberla Klaus Lentivirus based vector and vector system
WO1998040493A1 (en) * 1997-03-11 1998-09-17 The University Court Of The University Of Glasgow Fiv vaccine
WO1999004026A2 (en) * 1997-07-18 1999-01-28 Chiron Corporation Lentiviral vectors

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5650309A (en) * 1995-05-16 1997-07-22 The Regents Of The University Of California Viral vectors

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996028565A1 (en) * 1995-03-16 1996-09-19 Hisamitsu Pharmaceutical Co., Inc. Novel gene recombinant
WO1997012622A1 (en) * 1995-10-06 1997-04-10 The Salk Institute For Biological Studies Vector and method of use for nucleic acid delivery to non-dividing cells
WO1997020060A1 (en) * 1995-11-28 1997-06-05 The Johns Hopkins University School Of Medicine Conditionally replicating viral vectors and their use
WO1997020052A1 (en) * 1995-11-28 1997-06-05 Clinical Technologies, Inc. Recombinant hiv and modified packaging cells and method for treating acquired immune deficiency syndrome
WO1997031119A1 (en) * 1996-02-21 1997-08-28 Res Inst For Genetic And Human Methods and compositions for protective and therapeutic genetic immunization
WO1997032983A1 (en) * 1996-03-05 1997-09-12 The Regents Of The University Of California Recombinant live feline immunodeficiency virus and proviral dna vaccines
WO1998003669A2 (en) * 1996-07-22 1998-01-29 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Vectors for inhibiting hiv and tumor growth
WO1998039463A2 (en) * 1997-03-06 1998-09-11 Ueberla Klaus Lentivirus based vector and vector system
WO1998040493A1 (en) * 1997-03-11 1998-09-17 The University Court Of The University Of Glasgow Fiv vaccine
WO1999004026A2 (en) * 1997-07-18 1999-01-28 Chiron Corporation Lentiviral vectors

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DATABASE WPI Derwent World Patents Index; AN 1996-433836, XP002229729 *
NALDINI L ET AL: "IN VIVO GENE DELIVERY AND STABLE TRANSDUCTION OF NONDIVIDING CELLS BY A LENTIVIRAL VECTOR", SCIENCE, AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE,, US, vol. 272, no. 5259, 12 April 1996 (1996-04-12), pages 263 - 267, XP000583652, ISSN: 0036-8075 *
POESCHLA E ET AL: "DEVELOPMENT OF HIV VECTORS FOR ANTI-HIV GENE THERAPY", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, vol. 93, no. 21, 15 October 1996 (1996-10-15), pages 11395 - 11399, XP000616290, ISSN: 0027-8424 *
See also references of WO9930742A1 *

Also Published As

Publication number Publication date
JP2002508338A (en) 2002-03-19
AU749059B2 (en) 2002-06-20
WO1999030742A1 (en) 1999-06-24
EP1037669A1 (en) 2000-09-27
CA2314683A1 (en) 1999-06-24
AU1803599A (en) 1999-07-05
KR20010033062A (en) 2001-04-25

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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Effective date: 20000628

AK Designated contracting states

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Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: CELL GENESYS, INC.

RIN1 Information on inventor provided before grant (corrected)

Inventor name: SONG, JIN-PING

Inventor name: NALDINI, LUIGI

RIC1 Information provided on ipc code assigned before grant

Ipc: 7A 61P 31/18 B

Ipc: 7A 61P 31/14 B

Ipc: 7C 12N 15/86 B

Ipc: 7A 61K 48/00 A

A4 Supplementary search report drawn up and despatched

Effective date: 20030217

RAP1 Party data changed (applicant data changed or rights of an application transferred)

Owner name: CELL GENESYS, INC.

17Q First examination report despatched

Effective date: 20040907

STAA Information on the status of an ep patent application or granted ep patent

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18D Application deemed to be withdrawn

Effective date: 20060701