JP2002272819A - Soft contact lens treating method - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a soft contact lens treating method with a multi-purpose antiseptic solution, by which the adsorption of the components of the multi-purpose antiseptic solution to the lens is reduced so that immunity from harmfulness is enhanced and, the use of the multi-purpose antiseptic solution is reduced remarkably, compared with the present method, further the container of multi- purpose antiseptic solution is miniaturized to reduce the waste generation and economic burden on the user of the contact lenses. SOLUTION: The soft contact lens is soaked in the multi-purpose antiseptic solution of not more than 2 ml per a single lens to prevent disinfectant, a surfactant, etc., from adsorping to the lens.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a treatment method for cleaning and disinfecting a soft contact lens, and more particularly, to the treatment of a soft contact lens while reducing the adsorption of a drug to the lens and improving the safety of the wearer. The present invention relates to a method for treating a soft contact lens, which reduces the amount of liquid required for a treatment container and reduces the economic burden.

[0002]

2. Description of the Related Art Conventionally, thermal disinfection has been widely used as a method for disinfecting soft contact lenses, but recently, chemical disinfection has been used extensively.
A multipurpose chemical disinfection method in which disinfection and preservation are performed with one liquid has been spreading. In such a multipurpose chemical disinfection method, a soft contact lens is provided by using a portable contact lens case composed of a case body having a pair of left and right lens housings and a cap for removably sealing an opening of the housing. Is generally processed. In this case, the multipurpose disinfecting solution used is usually 4 to 6 ml for one eye, and 8 to 12 ml for both eyes. Furthermore, since the above-mentioned multipurpose disinfectant is used for cleaning and rinsing of the contact lens removed from the other eye, when the amount of use is large, it is 20 per day.
more than ml. For this reason, a large-capacity supply container for the multipurpose disinfecting solution is required, which not only imposes a large economic burden on the wearer but also increases the amount of waste due to the enlargement of the container.

On the other hand, components such as a bactericide and a surfactant contained in a multipurpose disinfecting solution are partially adsorbed to a soft contact lens during processing. In recent multi-purpose disinfectants, formulations have been developed to minimize the amount of adsorption to the lens,
Some adsorption is inevitable. In addition, the adsorption of the surfactant cannot be ignored. For this reason, even if an ophthalmologically acceptable bactericide or surfactant is used, it is desired to further suppress the amount of adsorption to the lens from the viewpoint of safety for the eyes.

[0004]

SUMMARY OF THE INVENTION The present invention has been made in view of the above circumstances, and an object of the present invention is to provide a multi-purpose disinfectant for treating a soft contact lens with a multi-purpose lens. Increased safety by further suppressing the amount of disinfectant components adsorbed compared to the current level, significantly reducing the amount of multipurpose disinfectant solutions used and reducing the amount of waste generated by miniaturizing the multipurpose disinfectant solution supply container Another object of the present invention is to provide a soft contact lens processing method that can reduce the economic burden on a contact lens wearer.

[0005]

In order to solve the above-mentioned problems, the present inventors have reduced the amount of the multi-purpose disinfecting solution with respect to the soft contact lens, thereby reducing the amount of the multi-purpose disinfecting solution and simultaneously increasing the multi-purpose disinfecting solution. It has been found that the amount of the disinfectant component adsorbed on the lens is suppressed.

That is, the present invention provides a method of treating a soft contact lens with a liquid containing an ophthalmologically acceptable bactericide, wherein the soft contact lens is immersed in the liquid of not more than 2 ml per lens. The gist is a method for treating a soft contact lens.

According to the present invention, the amount of the multipurpose disinfectant used is not more than 2 ml per eye, and the adsorbed amount of the multipurpose disinfectant such as a bactericide and a surfactant to the soft contact lens is reduced. There is. In addition, the supply container for the multipurpose disinfectant can be reduced in size as the amount of the multipurpose disinfectant used decreases, and the amount of waste can be reduced.

The bactericide component of the solution used in the method of the present invention is at least one selected from biguanide bactericides and / or salts thereof and quaternary ammonium salts generally used in ophthalmic solutions. Used.

The biguanide fungicide used in the present invention is preferably polyhexamethylene biguanide and chlorohexidine and / or a salt thereof. As polyhexamethylene biguanide, hydrochloride or the like is preferably used, and chlorhexidine is preferably gluconate. Alexidine
Bisbiguanide hydrochloride and the like can also be used. As the concentration of these disinfectants increases, the amount of adsorption to the soft contact lens increases. For safety reasons, the concentration of the biguanide-based disinfectant is 0.00001 w / v% or more and 0.0005% for polyhexamethylene biguanide.
w / v% or less, and in the case of chlorhexidine gluconate, it is preferably 0.0001 w / v% or more and 0.0008 w / v% or less.

The quaternary ammonium salt used in the present invention is preferably a high molecular weight quaternary ammonium salt, but a low molecular compound such as benzalkonium chloride or benzethonium chloride can also be used. As the polymer quaternary ammonium salt, a polyquaterium fungicide is preferable. Polyquaterium is CTFA (The Cosmetic)
Toiletry and France A
and its varieties are preferably polyquaterium-1, polyquaterium-6, polyquaterium-7, polyquaterium-16, and polyquaterium-22. Among polyquateriums, those having a relatively high positive charge are preferable in terms of bactericidal action, and in the case of a copolymer of a quaternary ammonium salt and another monomer, the higher the proportion of the quaternary ammonium salt, the higher the bactericidal effect. Is preferred. As a preferred example, polyquaterium-1 is used at a concentration of 0.00000 to 3.0 wt / v%.

It is desirable that the liquid preparation used in the method of the present invention contains a surfactant in order to improve the effect of removing dirt such as eye oil and the like adhered to the contact lens and to improve the cleaning effect. As a surfactant, if it is highly safe for living organisms and has little effect on contact lens materials,
Any type of surfactant, such as a cation, an anion, amphoteric or nonionic, can be used, but a nonionic surfactant is preferred. As the nonionic surfactant, polyoxyethylene / polyoxypropylene block copolymer, polyoxyethylene hydrogenated castor oil, tyloxapol and the like are used. The concentration is 0.01-0.5w
/ V% is preferred.

When a soft contact lens is immersed in a contact lens solution such as a multipurpose disinfecting solution to perform disinfection or the like, the soft contact lens adsorbs components such as a bactericide and a surfactant contained in the solution. Although it was generally thought that high-molecular germicides and surfactants were difficult to adsorb to soft contact lenses, studies conducted by the present inventors have revealed that even high polymers can adsorb to soft contact lenses. Was. Further, as the surfactant used in the multipurpose disinfecting solution, the above-mentioned nonionic surfactant is generally used, and it has been found that such a surfactant tends to be adsorbed to the soft contact lens.

In the method of the present invention, in order to suppress adsorption of the above-mentioned bactericide, surfactant and the like to the lens,
The amount of the liquid to be treated for disinfection or the like is set to 2 ml or less for one soft contact lens. If the liquid volume exceeds 2 ml, the amount of adsorbed bactericide, surfactant and the like increases, and the object of the present invention cannot be achieved. For this purpose, a soft contact lens and the above-mentioned liquid agent are accommodated in a contact lens case in which the capacity of the lens accommodating portion is 2 cm ³ or less per lens, and a treatment such as disinfection is performed. Preferably, the liquid amount of the liquid is 1.5 ml or less per lens. When the lens is immersed in the liquid, the bacteria attached to the lens begin to be killed by the germicide in the liquid. On the other hand, adsorption of the germicide in the liquid preparation to the soft contact lens is started. If the concentration of the germicide decreases due to adsorption, the rate of adsorption to the lens will decrease, thus limiting the amount of germicide adsorbed to the lens within the processing time. The lower limit of the amount of the liquid agent per lens is the minimum amount that allows the lens to be completely immersed in the liquid and is determined by the shape of the contact lens case. For example, the lens is sandwiched between sponges impregnated with the liquid agent. With such a method, the liquid volume can be reduced to 0.5 ml or less.

Since the disinfectant is easily adsorbed on the soft contact lens, it is desirable that the liquid used in the present invention has a low concentration and a high disinfecting effect.

In order to maintain a high bactericidal effect with a low concentration of a bactericide in the above liquid preparation, it is effective to use a nonionic tonicity agent and / or an amino acid as a tonicity agent.

Examples of the nonionic tonicity agent include glycerin, propylene glycol, mannitol, polyethylene glycol (average molecular weight: 100 to 600), glucose, diethylene glycol, sorbitol, xylitol, cyclodextrin and the like. But you can use it if it is safe. Among them, used alone or in combination as appropriate,
Among them, particularly, at least one of glycerin, propylene glycol and mannitol is preferably used. Particularly preferred is propylene glycol.

The amino acid used as the anisotonic agent is appropriately selected from known compounds having a carboxyl group and an amino group in the molecule, and preferably a low molecular weight amino acid having a molecular weight of 75 to 250 is advantageous. For example, alanine, α-amino adipic acid, α-aminobutyric acid, arginine, asparagine, isoleucine, creatine, glutamine, glycine, histidine, cystine,
Examples include tyrosine, tryptophan, valine, methionine, lysine, leucine, ornithine, phenylalanine, proline, phosphoserine, sarcosine, threonine, cysteine, and serine. Among them, glycine, DL-alanine, DL-serine, and L-histidine are preferable. , L-glutamine is used, and glycine is particularly preferably used.

By using a nonionic tonicity agent and / or an amino acid as a tonicity agent, a high bactericidal effect can be obtained with a low concentration of bactericide. For this reason, a sufficient disinfection effect can be obtained even when the concentration of the germicide is reduced, and the amount of the germicide adsorbed on the soft contact lens can be further reduced.

When the above-mentioned nonionic tonicity agent and / or amino acid is used in combination with the above-mentioned bactericide, the bactericidal efficacy can be remarkably enhanced. Further, it has been found that the addition of an amino acid salt has the effect of keeping the size of the soft contact lens constant during treatment with these solutions. As the amino acid salt, L-aspartate, L-glutamate, L-arginate, and the like are used, and L-aspartate and L-glutamate are preferred, and L-glutamate is particularly preferred. . Sodium salts are most commonly used as amino acid salts, but potassium salts, magnesium salts, calcium salts and the like can also be used. 0.1 when amino acid salt is added
It is preferably in the range of 0.6 w / v%. 0.6w
If the ratio is / v% or more, the bactericidal effect may be reduced.

The above-mentioned nonionic tonicity adjusting agent and / or amino acid adjusts the osmotic pressure of the solution in order to avoid irritation to the eyes. 200-400 mOsm in the range where the osmotic pressure of the treatment liquid is substantially equal to the physiological osmotic pressure.
It is determined to be. The osmotic pressure is preferably adjusted with a nonionic tonicity agent and / or an amino acid and an amino acid salt. If a large amount of an ionic tonicity agent such as sodium chloride is added, the bactericidal effect is reduced. Therefore, the amount of such an ionic tonicity agent is desirably 0.2 w / v% or less.

The pH of the solution used in the method of the present invention is usually adjusted to a substantially neutral range of pH 5 to 9, preferably pH 6 to 8. Even if the pH is lower than 5 or higher than 9, problems such as irritation to the eyes and inducing damage may occur. So such a p
At least one buffer is added to keep H.
The buffer used in the present invention is selected from various known ones. In general, a borate buffer, a phosphate buffer, a tris (hydroxymethyl) aminomethane buffer (Tris buffer), An acid buffer is used. The concentration of the buffer is 0.0
5 to 1.2 w / v%, preferably 0.1 to 0.8 w / v
%.

Further, a chelating agent is desirably added to the liquid used in the method of the present invention in order to remove inorganic dirt such as calcium. As the chelating agent, ethylenediaminetetraacetate is preferable. It is preferable that the concentration of ethylenediaminetetraacetate is 0.04 w / v% or less.

The liquid used in the method of the present invention may further contain a thickener, a protein remover, and the like. Any conventionally known substances can be used as long as they are safe for the living body and do not adversely affect the material of the contact lens. Can be included in a range that does not inhibit the action and effect of

In the method of the present invention, in order to prevent a decrease in the bactericidal effect when the lens is contaminated with an organic substance or the like, the lens is rubbed in advance with the above-mentioned liquid before immersing the lens in the above-mentioned liquid. It is desirable to perform processing such as washing and / or rinsing.

In the method of the present invention, a contact lens case having a capacity of a lens accommodating portion of 2 cm ³ or less is used. In order to completely immerse a contact lens in a liquid with such a small capacity, a treatment solution and a lens accommodating lens are required. It is preferable that the bottom surface of the portion has a shape forming a convex surface. Furthermore, when the convex surface of the soft contact lens is placed on the receiving portion having such a convex bottom surface, and the concave surface of the inner surface is received along the convex surface of the receiving portion bottom, when the lens is taken out of the case and worn on the eye, Since the outer surface side of the lens can be picked up and worn with a finger, it can be seen without touching the inner surface of the lens. For this reason, there is no fear that the inner surface of the lens is contaminated, which is advantageous for safety.

[0026]

Embodiment 1 Focusing using a contact lens case shown in FIGS. 1 to 3 (importer: Ciba Vision Co., Ltd.)
Was disinfected and stored. The concave inner surface of the focus lens is held on the left and right lens support portions 2 having a convex surface and a large number of water passage holes, and after tightening the upper cap 3, the case is turned over and the bottom is filled with liquid. A treatment liquid having the composition shown in Table 1 was injected from the waste hole 4. The volume of the injected liquid was 1.2 ml for both eyes. The processing liquid was filled in the space without any gap, and uniform processing of the lens could be performed. Since the liquid filling / disposing hole 4 communicates with the left and right processing liquid storage sections, the processing liquid injected from the liquid filling / disposing hole 4 was filled into the left and right processing liquid storage sections at one time. After leaving it overnight (12 hours) for disinfection and storage, the lower cap 5 was opened and the processing liquid was discarded from the liquid filling / disposing hole 4 at the bottom. The upper cap 3 was opened, and the lens placed on the lens support 2 was pinched on the outside with fingers, so that it could be removed from the case without touching the inside of the lens and attached to the eyes.

Table 1

Example 2 Formulation 1 containing 0.0005% polyhexamethylene biguanide hydrochloride (PHMB) (Table 1) and Formulation 1 as control
Was prepared by removing PHMB from Formulation 3. Next, a lens case having a capacity of 1 mL is prepared, and 1 mL of the prescription 1 is dispensed into the lens case, and the focus (importer: Ciba Vision Co., Ltd.) 1
The pieces were immersed. After allowing to stand at 25 ° C. for 4 hours, the lens was taken out, and the absorption of 235 nm was measured using Prescription 3 as a control, thereby quantifying the concentration of PHMB in the residual solution and measuring the amount of PHMB adsorbed in the lens. As a result, PHM
The adsorption amount of B was 3.58 μg / lens.

Example 3 A prescription 1 was prepared in the same manner as in Example 2, a lens case having a capacity of 0.75 mL was prepared, and 0.75 mL of the prescription 1 was dispensed into the lens case. Focus (importer: Ciba Vision Co., Ltd.) 1
The pieces were immersed. After allowing to stand at 25 ° C. for 4 hours, the amount of PHMB adsorbed in the lens was calculated in the same manner as in Example 2. As a result, the adsorption amount of PHMB was 2.67 μg / lens.

Table 2

Comparative Example 1 A prescription 1 was prepared in the same manner as in Example 2, a commercially available lens case having a capacity of 4 mL was prepared, and 4 mL of the prescription 1 was dispensed into the lens case.
One focus (importer: Ciba Vision Co., Ltd.) was immersed. After allowing to stand at 25 ° C. for 4 hours, the amount of PHMB adsorbed in the lens was calculated in the same manner as in Example 2. As a result, the adsorption amount of PHMB was 8.95 μg / lens.

Example 4 The same formulation 1 as in Example 2 was prepared, and one piece of Menicon Soft MA (Menicon Corporation) was immersed in a 1 mL lens case and allowed to stand at 25 ° C. for 4 hours. When the amount of PHMB adsorbed was determined in the same manner as in Example 2, it was 3.03 μg / lens.

Comparative Example 2 The same formulation 1 as in Example 2 was prepared, and one piece of Menicon Soft MA (Menicon Co., Ltd.) was immersed in a lens case having a capacity of 4 mL and allowed to stand at 25 ° C. for 4 hours. When the amount of PHMB adsorbed was determined in the same manner as in Example 2, it was 7.83 μg / lens.

Example 5 0.0005% of chlorhexidine gluconate (CH
G) containing Formula 2 (Table 1) and CH from Formula 2 as a control.
Formulation 3 excluding G was prepared. Next, a lens case having a capacity of 1 mL was prepared, 1 mL of Formulation 2 was dispensed into the lens case, and one focus (importer: Ciba Vision) was immersed. After allowing to stand at 25 ° C. for 4 hours, the lens was taken out, and the absorption of 233 nm was measured using formulation 3 as a control to quantify the concentration of CHG in the residual solution.
Was calculated. As a result, the adsorption amount of CHG was 3.
57 μg / lens.

Example 6 A prescription 2 was prepared in the same manner as in Example 5, a lens case having a capacity of 2 mL was prepared, 2 mL of the prescription 2 was dispensed into the lens case, and one focus (importer: Ciba Vision Co., Ltd.) was immersed. did. After standing at 25 ° C. for 4 hours, the amount of CHG adsorbed in the lens was measured in the same manner as in Example 5. As a result, the amount of CHG adsorbed was 6.21 μg / lens.

Comparative Example 3 A prescription 2 similar to that of Example 5 was prepared, a commercially available lens case having a capacity of 4 mL was prepared, and 4 mL of the prescription 2 was dispensed into the lens case.
One focus (importer: Ciba Vision Co., Ltd.) was immersed. After standing at 25 ° C. for 4 hours, the amount of CHG adsorbed in the lens was measured in the same manner as in Example 4.
The G adsorption amount was 11.13 μg / lens.

Example 7 0.001% of Mercoat 100 (manufactured by Calgon, Polyquaterium-6) and 0.025% of nonionic surfactant Nonion HS-220 (manufactured by NOF Corporation, polyoxyethylene (20 mol)) (Nonylphenyl ether) (Table 3) and as control, the nonionic HS-
Formulation 5 with the exception of 220 was prepared. Next, a lens case having a capacity of 1 mL was prepared, and 1 mL of Formulation 4 was dispensed into the lens case, and one piece of Menicon Soft MA (Menicon Corporation) was immersed. After standing at 25 ° C. for 4 hours, the lens was taken out, and the absorbance at 275 nm was measured using the prescription 5 as a control to quantify the concentration of HS-220 in the residual solution, and to adsorb nonionic HS-220 in the lens. The amount was calculated. As a result, the adsorption amount of Nonion HS-220 was 67.3 μg / lens.

Table 3

Comparative Example 4 A prescription 4 was prepared in the same manner as in Example 6, a commercially available lens case having a capacity of 4 mL was prepared, and 4 mL of the prescription 4 was dispensed into the lens case.
One piece of Menicon Soft MA (Menicon Corporation) was immersed. After standing at 25 ° C. for 4 hours, the amount of nonionic HS-220 adsorbed in the lens was measured in the same manner as in Example 5, and the amount of nonionic HS-220 adsorbed was 106.8 μg /
It was a lens.

Example 8 0.01% of a nonionic surfactant (Tetronic)
1107: polyoxyethylene, polyoxypropylene block copolymer, manufactured by BASF) and 0.0005%
Formula 6 containing polyhexamethylene biguanide hydrochloride (PHMB) (Table 4) and, as a control, from Formula 6
Formulation 7 excluding nic1107 was prepared. Then 1mL
A lens case having a capacity is prepared, and 1 mL of the prescription 6 is dispensed into the lens case, and focus (importer: Ciba Vision Co., Ltd.) 1
The pieces were dipped. After standing at 25 ° C. for 4 hours, the lens was taken out, and 1.4 mL of purified water was added to 0.7 mL of the remaining solution.
25% of 7.2% diluted hydrochloric acid, 10% barium chloride solution 15
μL and 15 μL of a 10% phosphomolybdic acid solution were added and mixed. The same operation was performed for the solution of Formulation 7, and the concentration of Tetronic 1107 in the remaining solution was quantified by measuring the absorption at 660 nm using this solution as a control solution to calculate the amount of Tetroic 1107 adsorbed in the lens. As a result, the adsorption amount of Tetronic 1107 was 3.0 μm.
g / lens.

Table 4

Comparative Example 5 A prescription 6 similar to that of Example 7 was prepared, a commercially available lens case having a capacity of 4 mL was prepared, and 4 mL of the prescription 6 was dispensed into the lens case.
One focus (importer: Ciba Vision Co., Ltd.) was immersed. After allowing to stand at 25 ° C. for 4 hours, the amount of adsorption of Tetronic 1107 in the lens was measured in the same manner as in Example 7. As a result, the adsorption amount of Tetronic 1107 was 12.1 μg / lens.

Example 9 Formulation 8 containing 0.0005% of polyhexamethylene biguanide hydrochloride (PHMB) (Table 5) and Formulation 8 as a control
To prepare Formulation 9 from which PHMB was removed. Then 1.5m
Prepare an L-capacity lens case, and add prescription 8
mL was dispensed, and one focus (importer: Ciba Vision Co., Ltd.) was immersed. After allowing to stand at 25 ° C. for 4 hours, the lens was taken out, and the absorption of 235 nm was measured using Formulation 9 as a control to quantify the concentration of PHMB in the residual solution, and the amount of PHMB adsorbed in the lens was measured. As a result, the adsorption amount of PHMB was 4.12 μg / lens.

Table 5

Comparative Example 6 A liquid preparation similar to that of Example 9 was prepared, a commercially available lens case having a capacity of 4 mL was prepared, 4 mL of Formulation 8 was dispensed into the lens case, and one focus (importer: Ciba Vision Co., Ltd.) was added. Dipped. After allowing to stand at 25 ° C. for 4 hours, as in Example 9,
The amount of PHMB adsorbed in the lens was calculated. As a result, P
The adsorption amount of HMB was 7.54 μg / lens.

Example 10 Formulation 8 containing 0.0005% of polyhexamethylene biguanide hydrochloride (PHMB) (Table 6) and Formulation 1 as a control
Formulation 11 was prepared by removing PHMB from 0. Then 0.8
A lens case having a capacity of mL was prepared, and 0.8 mL of the prescription 10 was dispensed into the lens case, and one focus (importer: Ciba Vision Co., Ltd.) was immersed. After allowing to stand at 25 ° C. for 4 hours, the lens was taken out, and 235 nm was determined using Formulation 11 as a control.
The concentration of PHMB in the residual liquid was quantified by measuring the absorption of, and the amount of PHMB adsorbed in the lens was measured. As a result, the adsorption amount of PHMB was 3.8 μg / lens.

Comparative Example 7 A prescription 10 similar to that of Example 10 was prepared, a commercially available lens case having a capacity of 4 mL was prepared, and 4 mL of the prescription 10 was dispensed into the lens case, and a focus (importer: Ciba Vision Co., Ltd.) 1
The pieces were dipped. After standing at 25 ° C. for 4 hours, Example 10
Similarly to the above, the adsorption amount of PHMB in the lens was calculated. As a result, the adsorption amount of PHMB was 12.9 μg / lens.

Table 6

[0049]

As is clear from the above description, according to the method of the present invention, even in a soft contact lens to which a bactericide is easily adsorbed, the amount of the bactericide adsorbed is suppressed and the safety to eyes is improved. Can be done. Also, the amount of liquid used is significantly reduced as compared with the conventional method, and the economic burden on the user is reduced. Further, since the container for the treatment liquid can be made small, not only is it convenient to carry around when traveling, but also the size of the container makes it possible to reduce waste after use and reduce the impact on the environment.

[Brief description of the drawings]

FIG. 1 is a perspective view of a contact lens case of the present invention as viewed from above.

FIG. 2 is a perspective view of the contact lens case of the present invention as viewed from the back side.

FIG. 3 is a cross-sectional view of the contact lens case of the present invention.

[Explanation of symbols]

 DESCRIPTION OF SYMBOLS 1 Processing liquid accommodation part 2 Lens support part 3 Upper cap 4 Liquid filling and disposal hole 5 Lower cap 6 Water passage hole 7 Main body

 ──────────────────────────────────────────────────続 き Continued on the front page F term (reference) 2H006 DA08 DA09 4C058 AA09 BB07 DD07 EE22 JJ06 JJ21 4H003 AC08 AC12 AE05 BA12 DA16 EB13 ED02 FA01 FA34

Claims (6)

[Claims] 1. A method of treating a soft contact lens with a solution containing an ophthalmically acceptable fungicide,
A method for treating a soft contact lens, wherein the soft contact lens is immersed in 2 ml or less of the above liquid agent per lens. 2. The bactericide is a biguanide bactericide such as polyhexamethylene biguanide or chlorohexidine, and / or
2. The method for treating a soft contact lens according to claim 1, which is at least one selected from the group consisting of salts thereof, polyquaterium-based germicides, quaternary ammonium salts such as benzalkonium chloride and benzethonium chloride. 3. The method according to claim 1, further comprising treating the soft contact lens with the solution containing a nonionic surfactant. 4. The method for treating a soft contact lens according to claim 1, further comprising treating the soft contact lens with the solution containing a nonionic tonicity agent and / or an amino acid. 5. The soft contact lens processing method according to claim 1, wherein the processing is performed using a contact lens case having a lens accommodation volume of 2 cm ³ or less. 6. The case where the bottom surface of the lens housing portion of the contact lens case has a convex shape.
The method for treating a soft contact lens according to the above.