JP2002255990A5 - - Google Patents
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- Publication number
- JP2002255990A5 JP2002255990A5 JP2001352543A JP2001352543A JP2002255990A5 JP 2002255990 A5 JP2002255990 A5 JP 2002255990A5 JP 2001352543 A JP2001352543 A JP 2001352543A JP 2001352543 A JP2001352543 A JP 2001352543A JP 2002255990 A5 JP2002255990 A5 JP 2002255990A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- formula
- nucleic acid
- acid synthesis
- carbon atoms
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- -1 2-oxo-1,2-dihydropyrimidin-1-yl group Chemical group 0.000 claims 15
- 125000003277 amino group Chemical group 0.000 claims 10
- 238000001668 nucleic acid synthesis Methods 0.000 claims 10
- 125000004432 carbon atom Chemical group C* 0.000 claims 9
- 125000006239 protecting group Chemical group 0.000 claims 9
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 6
- 125000000217 alkyl group Chemical group 0.000 claims 5
- 125000003396 thiol group Chemical group [H]S* 0.000 claims 4
- 150000001875 compounds Chemical class 0.000 claims 3
- 125000005159 cyanoalkoxy group Chemical group 0.000 claims 3
- 125000004191 (C1-C6) alkoxy group Chemical group 0.000 claims 2
- 125000003545 alkoxy group Chemical group 0.000 claims 2
- 125000004414 alkyl thio group Chemical group 0.000 claims 2
- 125000002103 4,4'-dimethoxytriphenylmethyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)(C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H])C1=C([H])C([H])=C(OC([H])([H])[H])C([H])=C1[H] 0.000 claims 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims 1
- 125000005426 adeninyl group Chemical group N1=C(N=C2N=CNC2=C1N)* 0.000 claims 1
- 150000001413 amino acids Chemical class 0.000 claims 1
- 125000001584 benzyloxycarbonyl group Chemical group C(=O)(OCC1=CC=CC=C1)* 0.000 claims 1
- 229910052799 carbon Inorganic materials 0.000 claims 1
- 125000005843 halogen group Chemical group 0.000 claims 1
- 125000002467 phosphate group Chemical group [H]OP(=O)(O[H])O[*] 0.000 claims 1
- 125000004545 purin-9-yl group Chemical group N1=CN=C2N(C=NC2=C1)* 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 125000001424 substituent group Chemical group 0.000 claims 1
- 125000004044 trifluoroacetyl group Chemical group FC(C(=O)*)(F)F 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2001352543A JP4255227B2 (ja) | 2000-11-21 | 2001-11-19 | Ｎ３’−ｐ５’結合を有する２’，４’−ｂｎａオリゴヌクレオチド |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2000-354326 | 2000-11-21 | ||
| JP2000354326 | 2000-11-21 | ||
| JP2001352543A JP4255227B2 (ja) | 2000-11-21 | 2001-11-19 | Ｎ３’−ｐ５’結合を有する２’，４’−ｂｎａオリゴヌクレオチド |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2002255990A JP2002255990A (ja) | 2002-09-11 |
| JP2002255990A5 true JP2002255990A5 (https=) | 2005-07-07 |
| JP4255227B2 JP4255227B2 (ja) | 2009-04-15 |
Family
ID=26604359
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001352543A Expired - Fee Related JP4255227B2 (ja) | 2000-11-21 | 2001-11-19 | Ｎ３’−ｐ５’結合を有する２’，４’−ｂｎａオリゴヌクレオチド |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP4255227B2 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPWO2017111137A1 (ja) | 2015-12-22 | 2018-10-18 | 味の素株式会社 | オリゴヌクレオチドの製造方法 |
| IL273274B2 (en) * | 2017-09-14 | 2023-12-01 | Janssen Biopharma Llc | Modified nucleoside phosphoramidites |
-
2001
- 2001-11-19 JP JP2001352543A patent/JP4255227B2/ja not_active Expired - Fee Related
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