JP2002255814A5 - - Google Patents
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- Publication number
- JP2002255814A5 JP2002255814A5 JP2001386850A JP2001386850A JP2002255814A5 JP 2002255814 A5 JP2002255814 A5 JP 2002255814A5 JP 2001386850 A JP2001386850 A JP 2001386850A JP 2001386850 A JP2001386850 A JP 2001386850A JP 2002255814 A5 JP2002255814 A5 JP 2002255814A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- composition according
- tetrahydrothieno
- cyclopropylcarbonyl
- fluorobenzyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000008194 pharmaceutical composition Substances 0.000 claims 10
- DTGLZDAWLRGWQN-UHFFFAOYSA-N prasugrel Chemical compound C1CC=2SC(OC(=O)C)=CC=2CN1C(C=1C(=CC=CC=1)F)C(=O)C1CC1 DTGLZDAWLRGWQN-UHFFFAOYSA-N 0.000 claims 3
- 150000003839 salts Chemical class 0.000 claims 3
- 239000011780 sodium chloride Substances 0.000 claims 3
- VEXZGXHMUGYJMC-UHFFFAOYSA-N HCl Chemical group Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims 2
- 229960001138 acetylsalicylic acid Drugs 0.000 claims 2
- 238000002399 angioplasty Methods 0.000 claims 2
- BSYNRYMUTXBXSQ-UHFFFAOYSA-N aspirin Chemical compound CC(=O)OC1=CC=CC=C1C(O)=O BSYNRYMUTXBXSQ-UHFFFAOYSA-N 0.000 claims 2
- 230000002490 cerebral Effects 0.000 claims 2
- 201000010099 disease Diseases 0.000 claims 2
- 230000002357 endometrial Effects 0.000 claims 2
- 230000002265 prevention Effects 0.000 claims 2
- 238000002271 resection Methods 0.000 claims 2
- 200000000008 restenosis Diseases 0.000 claims 2
- 101700019104 3SPM Proteins 0.000 claims 1
- 101700016269 3SPT Proteins 0.000 claims 1
- 206010002388 Angina unstable Diseases 0.000 claims 1
- 206010003658 Atrial fibrillation Diseases 0.000 claims 1
- 208000005189 Embolism Diseases 0.000 claims 1
- 206010061216 Infarction Diseases 0.000 claims 1
- 208000005764 Peripheral Arterial Disease Diseases 0.000 claims 1
- 206010062585 Peripheral arterial occlusive disease Diseases 0.000 claims 1
- 208000010110 Spontaneous Platelet Aggregation Diseases 0.000 claims 1
- 208000007718 Stable Angina Diseases 0.000 claims 1
- 208000007814 Unstable Angina Diseases 0.000 claims 1
- 239000004480 active ingredient Substances 0.000 claims 1
- 230000015572 biosynthetic process Effects 0.000 claims 1
- 238000005755 formation reaction Methods 0.000 claims 1
- VZCYOOQTPOCHFL-UHFFFAOYSA-N fumaric acid Chemical compound OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 claims 1
- 239000004615 ingredient Substances 0.000 claims 1
- 239000003112 inhibitor Substances 0.000 claims 1
- 230000002401 inhibitory effect Effects 0.000 claims 1
- 201000004332 intermediate coronary syndrome Diseases 0.000 claims 1
- 230000000302 ischemic Effects 0.000 claims 1
- 239000011976 maleic acid Substances 0.000 claims 1
- 239000000106 platelet aggregation inhibitor Substances 0.000 claims 1
- 201000011528 vascular disease Diseases 0.000 claims 1
Claims (10)
- ２−アセトキシ−５−（α−シクロプロピルカルボニル−２−フルオロベンジル）−４，５，６，７−テトラヒドロチエノ［３，２−ｃ］ピリジン又はその薬理上許容される塩と、アスピリンを有効成分として含有する医薬組成物。
- ２−アセトキシ−５−（α−シクロプロピルカルボニル−２−フルオロベンジル）−４，５，６，７−テトラヒドロチエノ［３，２−ｃ］ピリジンの薬理上許容される塩が塩酸塩又はマレイン酸塩である請求項１に記載の医薬組成物。
- ２−アセトキシ−５−（α−シクロプロピルカルボニル−２−フルオロベンジル）−４，５，６，７−テトラヒドロチエノ［３，２−ｃ］ピリジン又はその塩酸塩と、アスピリンを有効成分として含有する医薬組成物。
- 血栓もしくは塞栓によって引き起こされる疾病の予防又は治療のための請求項１乃至請求項３のいずれかに記載の医薬組成物。
- 血小板凝集によって誘発される疾患の予防又は治療のための請求項１乃至請求項３のいずれかに記載の医薬組成物。
- 血管形成術、血管内膜切除術もしくはステント留置後の再狭窄、安定もしくは不安定狭心症、脳虚血発作、梗塞、末梢動脈疾患、心房性細動の予防又は治療のための請求項１乃至請求項３のいずれかに記載の医薬組成物。
- 脳血管系の疾患の予防又は治療のための請求項１乃至請求項３のいずれかに記載の医薬組成物。
- 血管形成術、血管内膜切除術もしくはステント留置後の再狭窄の予防又は治療のための請求項１乃至請求項３のいずれかに記載の医薬組成物。
- 請求項１乃至請求項３のいずれかに記載の医薬組成物を含有する血小板凝集抑制剤。
- 請求項１乃至請求項３のいずれかに記載の医薬組成物を含有する血栓形成抑制剤。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2001386850A JP4874482B2 (ja) | 2000-12-25 | 2001-12-20 | アスピリンを含有する医薬組成物 |
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2000392983 | 2000-12-25 | ||
| JP2000-392983 | 2000-12-25 | ||
| JP2000392983 | 2000-12-25 | ||
| JP2001386850A JP4874482B2 (ja) | 2000-12-25 | 2001-12-20 | アスピリンを含有する医薬組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2002255814A JP2002255814A (ja) | 2002-09-11 |
| JP2002255814A5 true JP2002255814A5 (ja) | 2005-05-19 |
| JP4874482B2 JP4874482B2 (ja) | 2012-02-15 |
Family
ID=26606540
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001386850A Expired - Lifetime JP4874482B2 (ja) | 2000-12-25 | 2001-12-20 | アスピリンを含有する医薬組成物 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP4874482B2 (ja) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2612315A1 (en) * | 2005-06-17 | 2006-12-28 | Eli Lilly And Company | Dosage regimen for prasugrel |
| BRPI0719529B8 (pt) | 2006-12-07 | 2021-05-25 | Daiichi Sankyo Co Ltd | método para produzir uma preparação sólida |
| BRPI0719393B8 (pt) * | 2006-12-07 | 2021-05-25 | Daiichi Sankyo Co Ltd | composição farmacêutica |
| US20100280064A1 (en) * | 2006-12-07 | 2010-11-04 | Tomoyuki Watanabe | Pharmaceutical composition having improved storage stability |
| US20090291138A1 (en) * | 2006-12-07 | 2009-11-26 | Daiichi Sankyo Company, Limited | Film-coated preparation having improved stability |
| JP5289975B2 (ja) * | 2006-12-07 | 2013-09-11 | 第一三共株式会社 | マンニトール又は乳糖を含有する固形製剤 |
| KR20160033792A (ko) | 2007-04-27 | 2016-03-28 | 사이덱스 파마슈티칼스, 인크. | 클로피도그렐 및 설포알킬 에테르 사이클로덱스트린을 함유하는 제형 및 사용 방법 |
| EP2429291B1 (en) | 2009-05-13 | 2016-07-06 | Cydex Pharmaceuticals, Inc. | Pharmaceutical compositions comprising prasugrel and cyclodextrin derivatives and methods of making and using the same |
| EP2505196A4 (en) * | 2009-11-27 | 2013-05-01 | Univ Tokai Educational System | Antithrombotic agents |
| US9757395B2 (en) | 2012-12-20 | 2017-09-12 | Otitopic Inc. | Dry powder inhaler and methods of use |
| US9757529B2 (en) | 2012-12-20 | 2017-09-12 | Otitopic Inc. | Dry powder inhaler and methods of use |
-
2001
- 2001-12-20 JP JP2001386850A patent/JP4874482B2/ja not_active Expired - Lifetime
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