JP2002226387A - Medicine producer from eggplant - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain a medicine prepared from a plant, low in side effects, useful for therapy of external injuries, heat injury, corn, verruca, pimple, eruption, athlete's foot, abscess, tumor, or the like. SOLUTION: This medicine is prepared from eggplant and comprises powder obtained by crushing the eggplant, freezing and drying the crushed product at <=-10 deg.C under reduced pressure.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

TECHNICAL FIELD The present invention relates to a medicine.
The invention more particularly relates to a medicament prepared from eggplant.

[0002]

2. Description of the Related Art In recent years, various drugs developed using chemical synthesis techniques for treating various diseases, traumas and swellings have been marketed. Pharmaceutical products obtained using such synthetic techniques may certainly have the desired efficacy, but in some cases may have unexpected side effects. On the other hand, since ancient times, plants, especially herbs, have been known as pharmaceuticals that have few side effects and can be used with confidence.

[0003]

DISCLOSURE OF THE INVENTION The present invention is a medicament prepared from a plant and having few side effects, and is particularly useful for treating trauma, burns, fish eyes, warts, acne, pimples, athlete's foot, swelling and tumors. It is an object to provide pharmaceutical products.

[0004]

Means for Solving the Problems The present inventor has conducted various studies to solve the above-mentioned problems, and as a result, the above-mentioned problem is a medicine manufactured from eggplant, and the medicine is the eggplant. Was crushed and freeze-dried at a reduced pressure of -10 ° C or lower under reduced pressure to obtain a pharmaceutical product characterized by being found to be able to solve the problem. Hereinafter, the present invention will be described in more detail.

[0005]

BEST MODE FOR CARRYING OUT THE INVENTION The drug of the present invention is a drug comprising dried powder of eggplant. The eggplant used in the present invention is not particularly limited. For example, the varieties of eggplant used in the present invention include (1) Senari, Tsurugoboso, Shinkuro, Yamanasasu, Kitada, and Kitapura. Tamurasaki), Sennarinas such as Early Dwarf Purple and Dwarf Japanese; (2) Naganas such as Sadohara, Hakata, Kurume, Takagi, Kumamoto, Nagasaki, Tsuda, Tsubame and Sendai, and (3) ) Hebinas, such as Chief of China, Chief of Seongoku, Mizuna of Minami, and Snake, (4) Margins such as purse (kinkaku), Osaka Maru, Echigo Maru, Serikawa "and Daisen Maru,
(5) Tamagonas, such as Sironas, Ginnas, and Kinnass; (6) American Onus, such as Black Beauty and New York Purple; and (7) Aonas. In the present invention, the pharmaceutical of the present invention can be prepared by using such conventionally well-known eggplants.

[0006] Eggplants as described above contain plant alkaloids. The alkaloids contained in this eggplant are
Mitosis of cells can be arrested in metaphase and tumor growth can be suppressed. Alkaloids are nitrogenous basic compounds present in the plant kingdom. Alkaloids contained in such eggplants generally show strong alkalinity and combine with acids to form salts. Generally, alkaloids contain carbonic acid, hydrogen, nitrogen and oxygen. Many of the chemical structures of alkaloids contained in eggplants are nitrogen-containing cyclic compounds, which are derivatives of pyridine, quinoline, and imidazole. Many naturally occurring alkaloids are levorotatory. This levorotatory alkaloid is generally said to have a stronger effect than dextrorotatory alkaloids. Therefore, the alkaloid contained in the eggplant has a strong action on the living body and has an excellent pharmacological action.

[0007] In the present invention, eggplant is used to prepare a pharmaceutical containing the plant alkaloid contained in eggplant as an active ingredient as described above. Here, in the present invention, the portion of the eggplant used is not particularly limited, and the medicament of the present invention is prepared using all parts of the eggplant fruit, leaves, stems, roots and the like. However, in the present invention, it is preferable to use eggplant fruits. More preferably, among the eggplant fruits, the eggplant nuts
It is preferable to use a site in the vicinity. The area near the ridge of the eggplant fruit is particularly rich in plant alkaloids. It is also preferable to use a seed among eggplant fruits. Eggplant seeds are rich in plant alkaloids suitable for the present invention.

Although the present invention is not limited by a particular theory, eggplants are used as they are in the pharmaceutical of the present invention as a preferred embodiment, and thus, vitamins and sugars other than the above-mentioned alkaloids are used. All the eggplant constituents such as and dietary fiber will be included in the medicament of the present invention. The drug of the present invention has a very effective effect due to the interaction between the eggplant constituents other than the alkaloid and the alkaloid. That is, with only the isolated eggplant alkaloids,
It is considered that a drug with sufficient efficacy cannot always be obtained. Needless to say, a pharmaceutical comprising an isolated eggplant alkaloid is also included in the scope of the present invention.

The medicament of the present invention has various effects. Illustrative effects are useful for treating burns such as fish eyes, octopus, warts, acne, prawns, pimples, athlete's foot, athlete's foot, stomatitis, stomatitis, and trauma. The medicament of the present invention has an excellent bactericidal action and increases the natural healing power of the affected part. In addition, the drug of the present invention is considered to show excellent efficacy against malignant tumors such as stomach cancer, esophageal cancer, tongue cancer, colorectal cancer, liver cancer and skin cancer. It is thought to prevent the growth of cancer cells.

[0010] The medicament according to the present invention is in various forms. Examples of the form of the medicament of the present invention include a dry powder, an aqueous solution, an ointment and the like. Next, methods for preparing various pharmaceuticals according to the present invention will be exemplified.

Pharmaceuticals in Dry Powder When preparing the pharmaceuticals of the present invention in a dry state, methods for adjusting eggplant fruits so as not to destroy the plant alkaloids contained therein are studied. Examples of such a drying method include a conventionally known drying method such as a heat drying method and a freeze drying method, and the latter is more preferable.

That is, a preferred method of preparing the pharmaceutical of the present invention is a method of freeze-drying eggplant (freeze-drying method). According to this method, the aubergine fruits, under reduced pressure, at low temperatures, preferably -10 degrees Celsius or less, more preferably -30 degrees Celsius or less, even -40 degrees Celsius or less, and optimally -50 degrees Celsius or less, Optimally, it cools rapidly below minus 80 degrees Celsius. As a result, the moisture is solidified and sublimated from the eggplant nuts, removed and dried. In addition, the reduced pressure condition in the case of the frozen powder is not particularly limited, but it is preferable that the reduced pressure be reduced to 5 mmHg or less. When the eggplant nuts are dried by the freeze-drying method, the alkaloids contained in the eggplant nuts are not decomposed, so that they can be stored for a long period of time, and can produce the medicament of the present invention rich in active ingredients. is there.

The powdered pharmaceutical prepared as described above is immersed in water to form a slurry before use.
It is applied to the affected area. The amount of water for making slurry is
Although not particularly limited, water is preferably 1 to 100 parts by weight, more preferably 2 to 50 parts by weight, and most preferably 3 to 20 parts by weight with respect to 1 part by weight of the dry powder.

Pharmaceutical product of the present invention in a solution state The pharmaceutical product of the present invention may be provided as a solution. The method for preparing the drug in the solution state is not particularly limited. For example, there is a method in which eggplant powder in a dry powder state as described above is prepared by dissolving it in water. Alternatively, the eggplant berries immediately after harvest may be made into a juice with a mixer, and the filtrate obtained by filtering the juice may be subjected to antiseptic treatment to obtain the pharmaceutical of the present invention. Further, from the filtrate obtained by filtering the eggplant nut juice, the plant alkaloid, which is the active ingredient of the present invention, is purified by extraction or the like, and this is dissolved in an aqueous solvent such as water or ethanol. You may get a medicine.

Pharmaceutical in Ointment The pharmaceutical of the present invention may be in the form of an ointment. This ointment contains plant alkaloids found in eggplant nuts.

Embodiment 1 Next, the present invention will be described in more detail based on embodiments. Prepare 10 kg of eggplant just after harvest. The surface of the eggplant fruit was washed with water and dried. Next, the eggplant was put into a large mixer, and the mixer was operated for about 20 minutes to obtain eggplant fruit juice. The eggplant fruit juice thus obtained was freeze-dried with a commercially available freeze-drying machine. Drying conditions were minus 40 degrees Celsius and 1 mmHg. The obtained dry block was pulverized with a pulverizer to obtain the pharmaceutical product 1 for powder of the present invention.

Efficacy against Warts The pharmaceutical product 1 obtained as described above was applied to patients with warts on the head. The wart of this patient was formed on the forehead forehead, was a substantially circular black thing having a diameter of about 8 mm, and protruded from the forehead. This wart is painful to touch.

In using the pharmaceutical product 1 of the present invention, about 0.5 g of pharmaceutical powder was placed in a container, 10 ml of water was added thereto, and the mixture was sufficiently stirred with a spoon to form a slurry. The drug in the slurry state was applied to the affected area. The drug was applied three times a day.

Immediately after the application of the pharmaceutical product 1 of the present invention, signs of improvement gradually appeared. In about one week, the pain was almost completely eliminated, and in about one month, the wart almost disappeared from the forehead. Side effects were hardly confirmed.

The wart is a human wart virus (HP).
V). Warts can also occur on the fingers and face, but they need to be diagnosed carefully because they look like chicken eyes (fish eyes) on the soles of the feet. Conventionally, this wart has been treated by cryotherapy using liquid nitrogen, but this cryotherapy was painful, but the medicine of the present invention is simply applied to the affected area (wart). No pain at all.

Effect on Fish Eyes The above-mentioned powdered medicine 1 was similarly applied to a patient with soles of fish eyes. The eye of the fish in this patient was formed on the sole of the foot, and the skin surface was firm and rigid and slightly reddish. The eyes of the fish were so painful to touch that they could not wear shoes. .

In using the pharmaceutical product 1 of the present invention, about 1 gram of the pharmaceutical powder was placed in a container, 5 ml of water was added thereto, and the mixture was sufficiently stirred with a spoon to form a slurry. Drug 1 in this slurry state was applied to the affected area. This drug 1 was applied three times a day.

Immediately after the application of the pharmaceutical product 1 of the present invention, signs of improvement gradually appeared. In about a week, the pain had almost disappeared and he had recovered enough to walk with his shoes. Side effects were hardly confirmed.

Example 2 10 kg of eggplant immediately after harvest is prepared. The surface of the eggplant fruit was washed with water and dried. Next, the eggplant was put into a large mixer, and the mixer was operated for about 20 minutes to obtain eggplant fruit juice. The thus obtained eggplant fruit juice was filtered to obtain a filtrate.
Eggplant plant alkaloids were purified from the filtrate using a conventionally known purification technique such as a solvent extraction method or a salting-out method.
The plant alkaloid thus obtained was dissolved in water to obtain a 10% by weight aqueous solution of eggplant alkaloid. This is designated as pharmaceutical product 2 of the present invention. This medicine 2 is designed to be applied or administered as it is.

Efficacy against Malignant Tumor Immediately after administration of the pharmaceutical product 2 of the present invention, cancer patients gradually showed signs of improvement. Then, after about 2 months, it was confirmed that the cancer cells became smaller. Side effects were hardly confirmed. In the treatment of this cancer, it may be used together with other anti-cancer treatments.

[0026]

As described above, the medicament of the present invention contains an alkaloid contained in eggplant as an active ingredient, and is capable of effectively recovering from various diseases, trauma, swelling, and the like. is there. In addition, the medicament of the present invention is produced from eggplant which exists in nature and has been eaten since ancient times, and almost no side effects on the human body were confirmed.

Further, according to a preferred embodiment of the present invention, since this medicine is produced without using any chemical treatment using eggplant obtained as a blessing of nature, it has no adverse effect on the human body. Very little, it can greatly increase the natural healing power inherent in humans.

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Claims (1)

[Claims] 1. A medicinal product produced from eggplant, wherein the medicament is obtained by crushing the eggplant and subjecting the eggplant to a pressure of minus 1 degree Celsius under reduced pressure.
A medicament characterized by comprising a powder which has been frozen and dried at a temperature of 0 ° C or less.