JP2002186590A - Method for measuring pulse, monitoring pulse, and monitoring pulse and blood pressure, system for measuring pulse, monitoring pulse, and pulse and blood pressure in artificial dialysis - Google Patents

Abstract

PROBLEM TO BE SOLVED: To continuously measure a patient's pulse during a dialytic treatment. SOLUTION: A supervisory processing computer 6 counts a wave number per unit measuring time from a deformation signal obtained by measuring a deformed amount of the midway of the tube 2 for feeding a blood to a dialyzer 4, and obtains the number of pulses of the patient 1 from the counted wave number.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a pulse measuring method for continuously measuring the pulse rate of a patient during dialysis treatment by measuring the amount of deformation of an elastic tube connecting a dialyzer and a patient, and a pulse monitoring method. Methods, pulse and blood pressure monitoring methods, and systems using these methods.

[0002]

2. Description of the Related Art During treatment by artificial dialysis, blood drawn from the patient's body by driving a pump passes through a dialyzer, and a dialysate and a hollow fluid flowing outside a hollow fiber provided in the dialyzer. Due to the osmotic pressure difference from the blood flowing inside the thread, waste and moisture in the blood are removed and purified. During such dialysis treatment, the patient's pulse may fluctuate rapidly. For this reason, during the dialysis treatment, medical personnel such as nurses visit the clinic and measure the pulse intermittently at a frequency of about once an hour. The measurement of the pulse is performed directly by the healthcare professional.For example, the healthcare professional's finger is placed over the artery in the arm of the dialysis patient, and the pulse of the artery is sensed by the finger while measuring the time with a wristwatch or the like. Detect and measure the pulse.

[0003]

In this manner, in the manner in which a medical worker performs a pulse measurement while patrol, the measurement frequency is about once an hour, so that a rapid change in the state of a dialysis patient is performed. There was a problem that it was difficult to deal with. In order to solve this problem, it is conceivable to frequently measure the pulse, but this is not preferable because an excessive burden is imposed on the medical staff.

[0004] Also, dialysis treatment is generally performed over a long period of 4 to 5 hours, and during this treatment period, the dialysis patient receives
He sleeps, watches TV, and reads. However, at the time of measuring the pulse, the action that had been performed must be stopped, which is a cause of stress.

The present invention has been proposed in view of the above, and has as its object to provide a pulse measuring method in artificial dialysis, a pulse monitoring method, a pulse and blood pressure monitoring method in dialysis, which can continuously measure a patient's pulse during dialysis treatment. And a system using these methods.

[0006]

Means for Solving the Problems The present invention has been proposed to achieve the above object, and the invention described in claim 1 is to reduce the amount of deformation of the tube in the middle of the tube for sending blood to the dialyzer. This is a pulse measurement method in artificial dialysis, wherein the number of waves per unit measurement time is counted from a deformed signal obtained by measurement, and the pulse rate during dialysis of a dialysis patient is obtained from the counted wave numbers.

[0007] Here, "the amount of deformation of the tube" means the amount of deformation of the tube corresponding to the internal pressure of blood flowing through the tube, and not only the amount of deformation of the tube diameter but also the position of the tube at a position shifted from the center. It also includes the amount of deformation of the tube diameter, the amount of bending and expansion and contraction of the tube side, and the like.

According to a second aspect of the present invention, the number of waves per unit measurement time is counted by counting the peak of the waveform corresponding to the patient's systolic blood pressure over the unit measurement time. 2. A pulse measuring method in artificial dialysis according to item 1.

According to a third aspect of the present invention, the measurement point of the tube is set near the connecting needle inserted into the arterial puncture portion, and the artificial dialysis device according to the first or second aspect, Is a pulse measurement method in the above.

According to a fourth aspect of the present invention, an allowable variation range of the pulse rate is set for each dialysis patient, and a deformation signal obtained by measuring a deformation amount of the tube in the middle of the tube for sending blood to the dialyzer is obtained. Count the number of waves per unit measurement time, calculate the pulse rate during dialysis of the dialysis patient from the counted wave number, monitor whether the pulse rate during dialysis is within the allowable fluctuation range, and monitor the pulse rate during dialysis with the allowable fluctuation. A pulse monitoring method in artificial dialysis, which outputs a warning signal on condition that the pulse is out of the range.

According to a fifth aspect of the present invention, an allowable fluctuation range of the pulse rate and an allowable fluctuation range of the systolic blood pressure are set for each dialysis patient, and the amount of deformation of the tube in the middle of the tube for sending blood to the dialyzer is measured. After obtaining the deformation signal and counting the number of waves per unit measurement time from the obtained deformation signal, the pulse rate during dialysis of the dialysis patient is calculated from the counted wave number, while the systolic blood pressure during dialysis is obtained from the obtained deformation signal. Calculate the value, and monitor whether the calculated pulse rate during dialysis is within the permissible fluctuation range, and monitor whether the calculated systolic blood pressure value during dialysis is within the permissible fluctuation range. A pulse and blood pressure monitoring method in dialysis, wherein a warning signal is output on condition that at least one of the systolic blood pressure values is out of an allowable fluctuation range.

According to a sixth aspect of the present invention, there is provided a tube deformation measuring means which is disposed in the middle of a tube for sending blood to a dialyzer, measures a deformation amount of the tube and outputs a deformation signal, and the tube deformation measuring means. Wave number counting means for counting the number of waves per unit measurement time based on the output deformation signal, and pulse rate calculating means for calculating a pulse rate during dialysis of a dialysis patient from the wave number counted by the wave number counting means, A pulse measuring system in artificial dialysis characterized by the following.

According to a seventh aspect of the present invention, the wave number counting means counts the number of waves per unit measurement time by counting the peak of the waveform corresponding to the systolic blood pressure of the patient over the unit measurement time. A pulse measuring system in artificial dialysis according to claim 6, characterized in that:

The invention according to claim 8 is characterized in that the tube deformation measuring means is disposed in the middle of a tube for sending blood to the dialyzer, measures the amount of deformation of the tube and outputs a deformation signal, and the tube deformation measuring means. Wave number counting means for counting the number of waves per unit measurement time based on the output deformation signal, and a starting pulse rate for calculating a starting pulse rate of a dialysis patient at the start of dialysis from the wave numbers counted by the wave number counting means Calculating means, a dialysis pulse rate calculating means for calculating a dialysis pulse rate of a dialysis patient during dialysis treatment from the wave number counted by the wave number counting means, and a measurement start time from the dialysis pulse rate and the starting pulse rate. A fluctuation degree calculating means for calculating the fluctuation degree of the reference pulse rate, and a predetermined allowable fluctuation degree of the pulse rate fluctuation calculated by the pulse fluctuation amount calculating means. Monitoring means for monitoring the range or not,
A pulse monitoring system for artificial dialysis, comprising: a warning signal output unit that outputs a warning signal when the degree of fluctuation of the pulse rate during dialysis falls outside an allowable fluctuation range.

According to a ninth aspect of the present invention, there is provided a tube deformation measuring means which is disposed in the middle of a tube for sending blood to the dialyzer, measures the amount of deformation of the tube and outputs a deformation signal, and information relating to dialysis of a dialysis patient. , A wave number counting means for counting the number of waves per unit measurement time based on the deformation signal output by the tube deformation measuring means, and a dialysis of the dialysis patient based on the wave number counted by the wave number counting means. A pulse rate calculating means for calculating a medium pulse rate, an allowable fluctuation range setting means for setting an allowable fluctuation range of the pulse rate during dialysis based on the dialysis-related information inputted by the personal information input means, and a pulse rate calculating means. Monitoring means for monitoring whether or not the calculated dialysis pulse rate is within the allowable fluctuation range; and a warning on condition that the dialysis pulse rate is out of the allowable fluctuation range. And alarm signal output means for outputting a signal, a pulse monitoring system in dialysis, characterized in that it comprises a.

According to a tenth aspect of the present invention, there is provided a tube deformation measuring means which is disposed in the middle of a tube for sending blood to a dialyzer, measures a deformation amount of the tube and outputs a deformation signal, and the tube deformation measuring means. Wave number counting means for counting the wave number per unit measurement time based on the output deformation signal, and start pulse rate calculation for calculating the start pulse rate of the dialysis patient at the start of dialysis from the wave number counted by the wave number counting means Means, a pulse rate calculator during dialysis for calculating a pulse rate during dialysis of a dialysis patient during dialysis treatment from a wave number counted by the wave number counting means, and a measurement start time based on the pulse rate during dialysis and the pulse rate at the start. At the start of dialysis on the basis of a deformation signal output by the tube deformation measuring means, Starting tube diameter acquisition means for acquiring the tube diameter of the expanding period as the starting tube diameter, and dialysis of the expanding tube diameter during the dialysis treatment based on the deformation signal output by the tube deformation measuring means. The dialysis tube diameter obtaining means for obtaining as the tube diameter, the deformation ratio calculation means for calculating the deformation rate of the tube based on the measurement start time from the dialysis tube diameter and the starting tube diameter, and the variation degree calculation means are calculated. Monitoring means for monitoring whether the degree of variation of the pulse rate and the deformation rate of the tube calculated by the deformation rate calculating means are within a predetermined allowable variation range, and at least one of the degree of variation of the pulse rate and the deformation rate of the tube Comprises a warning signal output means for outputting a warning signal on condition that the value falls outside a predetermined allowable fluctuation range. A monitoring system of the pulse and blood pressure in dialysis to.

An eleventh aspect of the present invention provides a tube deformation measuring means which is disposed in the middle of a tube for sending blood to a dialyzer, measures the amount of deformation of the tube and outputs a deformation signal, and information relating to dialysis of a dialysis patient. , A wave number counting means for counting the number of waves per unit measurement time based on the deformation signal output by the tube deformation measuring means, and a dialysis of the dialysis patient based on the wave number counted by the wave number counting means. A pulse rate calculating means for calculating a medium pulse rate, a systolic blood pressure value calculating means for calculating a systolic blood pressure value during dialysis based on a deformation signal output by the tube deformation measuring means, and a personal information input means. Allowable fluctuation range setting means for setting the allowable fluctuation range of the pulse rate during dialysis and the allowable fluctuation range of the systolic blood pressure value during dialysis based on the dialysis-related information Monitoring means for monitoring whether the pulse rate during dialysis calculated by the pulse rate calculating means and the systolic blood pressure value during dialysis calculated by the systolic blood pressure calculating means are within the permissible fluctuation range, and a pulse rate during dialysis and a pulse rate during dialysis. A pulse and blood pressure monitoring system in artificial dialysis, comprising: a warning signal output unit that outputs a warning signal on the condition that at least one of the hypertension values is out of an allowable fluctuation range.

[0018]

Embodiments of the present invention will be described below with reference to the drawings. 1 is a schematic configuration diagram of an artificial dialysis system, FIGS. 2 and 3 are diagrams illustrating a tube deformation measurement sensor, FIG. 4 is a diagram illustrating a deformation signal from the tube deformation sensor during dialysis treatment, and FIG. 5 is a monitoring process. Is a schematic configuration diagram of a computer for use.

The artificial dialysis system, as shown in FIG.
Tube 2 through which blood derived from the body of patient 1 passes
A pump 3 provided in the middle of the tube 2 and serving as a circulating drive source for sending blood in the tube 2; a dialyzer 4 for removing waste and excess water in the blood; Measure the amount of tube deformation,
It comprises a tube deformation measuring sensor 5 (corresponding to a tube deformation measuring means of the present invention) for outputting a measurement result as a deformation signal, and a monitoring processing computer 6. The tube deformation measuring sensor 5 and the monitoring computer 6 constitute a pulse measuring system.

The tube 2 forms an artificial dialysis circulation processing circuit together with the dialyzer 4, and is made of an elastic hollow member, for example, a synthetic resin material. The tube 2 includes an arterial tube 2a and a venous tube 2b.
It is composed of The arterial tube 2 a communicates between the patient 1 and the dialyzer 4. One end of the arterial tube 2a is a connection needle connectable to an arterial puncture portion (not shown) formed on the arm surface by an arteriovenous shunt formed on one arm of the patient 1. The other end of the tube 2a is connected to the blood inlet of the dialyzer 4. The pump 3 is connected to the arterial tube 2a.
Are disposed at positions closer to the dialyzer 4 side. The venous tube 2b communicates between the dialyzer 4 and the patient 1. That is, one end of the venous tube 2b is connected to the blood outlet of the dialyzer 4, and the other end is a connection needle connectable to a venous puncture part (not shown).

The dialyzer 4 is configured so that the blood of the patient 1 and the dialysate can come into contact with each other with a blood purification membrane interposed therebetween.
The waste and excess water in the blood are moved into the dialysate, and the necessary components are moved from the dialysate into the blood.

The tube deformation measuring sensor 5 is located in the middle of the arterial tube 2a (specifically, between the connecting needle and the pump 3).
And is arranged as close to the arterial puncture of the patient 1 as possible. That is, the tube deformation measuring sensor 5
Is disposed at one end of the arterial tube 2a, and this one end is used as a measurement point. The tube deformation measuring sensor 5 is provided by focusing on the fact that there is a certain correlation, for example, a substantially proportional relationship between the blood pressure in the tube 2 (the internal pressure of the blood flow) and the amount of electricity based on the deformation of the tube 2. In the present embodiment, the amount of deformation of the diameter of the tube 2 is measured.

As shown in FIGS. 2 and 3, the tube deformation measuring sensor 5 in this embodiment is a box-shaped case 1.
1, a deformation sensor 12 mounted downward in the case 11, and a grip 13 provided on the lower side of the case 11 and supporting the tube 2 in a substantially horizontal direction (left and right directions in the figure). Have been.

The deformation sensor 12 has a cylindrical sensor case 1.
4 and a movable rod 15 (a type of movable member) fitted into the sensor case 14.
5 is attached to the sensor case 14 so as to be movable in the axial direction. The deformation sensor 12 is arranged in such a direction that the distal end 15 a of the movable rod 15 can come into contact with the upper end of the tube 2 supported by the grip 13 from above. Accordingly, the movable rod 15 is urged downward by its own weight, and is displaced in the vertical direction with a deformation such as expansion and contraction of the tube 2. For example, when the blood pressure in the tube 2 rises and the tube 2 expands, the movable rod 15
Moves upward. When the raised blood pressure decreases and the tube 2 contracts, the movable rod 15 moves downward.
Then, the vertical movement of the movable rod 15 is detected by the displacement detecting element 16, and the displacement detecting element 16 outputs an electric signal of a level (for example, a voltage level) according to the moving amount of the movable rod 15 as a deformation signal. Note that the displacement detection element 16 of the present embodiment is configured to output an electric signal of a higher voltage level as the movable rod 15 rises.

Here, the diameter of the arterial tube 2a during the dialysis treatment has the smallest diameter during the diastolic period when the heart of the patient 1 has expanded the most, and has the largest diameter during the systolic period when the heart has contracted the most. For this reason, the deformation signal output during the dialysis treatment by the tube deformation measuring sensor 5 attached in the middle of the arterial tube 2a has the lowest voltage level during the diastole of the patient 1 and the highest voltage level during the systole. Becomes For example, as shown in FIG. 4, this deformed signal indicates the pulsation of the artery caused by the pulsation of the heart, and reaches the highest level at the time of systolic blood pressure (arterial pressure during systole of the heart) and at the time of diastolic blood pressure (heart rate). (The arterial pressure during the diastolic phase of the subject) becomes a continuous mountain-like or wave-like electrical signal having the lowest level.

It should be noted that the degree of deformation of the arterial tube 2a increases as it approaches the arteriovenous shunt of the patient 1 and decreases as it moves away from the arteriovenous shunt. Therefore, the amplitude of the deformation signal shown in FIG. 4 also increases as the measurement point of the tube deformation measurement sensor 5 approaches the arteriovenous shunt, and decreases as the measurement point moves away from the arteriovenous shunt. And in this embodiment, the tube deformation measurement sensor 5 is
Since it is arranged near the connecting needle which is the portion of the artery-side tube 2a having the highest degree of deformation, and this position is used as a measurement point, highly accurate measurement is possible.

As shown in FIG. 5, the monitoring processing computer 6 includes a control unit 21 composed of a CPU and the like, a ROM 22 storing an operation program of the control unit 21 and the like.
A RAM 23 used by the control unit 21;
1 is composed of an input device 24 for inputting information and an input / output interface 25.

The control section 21 functions as the wave number counting means of the present invention. That is, based on the deformation signal output from the tube deformation measurement sensor 5, the number of waves per unit measurement time is counted. The unit measurement time can be set in a range from several tens of seconds to several minutes, and is set to one minute in the present embodiment. The wave number can be counted by any method as long as the wave number can be counted. For example, peaks or valleys in the waveform of FIG. 4 may be counted. In the present embodiment, the wave number is counted by counting the peak (inflection point) of the mountain indicated by the symbol P, that is, by counting the peak of the waveform corresponding to the systolic blood pressure of the patient 1.

The deformation signal obtained by measuring the deformation amount of the tube 2 includes the discharge pressure of the pump 3 as noise. In order to remove this noise, a band-pass filter (not shown) is incorporated in the control unit 21 of the monitoring computer 6. Then, only the blood pressure value component (a component that varies according to the blood pressure) in the deformed signal is selected by the bandpass filter, thereby increasing the measurement accuracy.

Various methods can be used to detect the peak P. In this embodiment,
The difference between the voltage level of the deformed signal obtained in the previous sampling cycle and the voltage level of the deformed signal obtained in the current sampling cycle is calculated every time the voltage level is sampled, and it is determined that this difference has switched from positive to negative. The peak P is detected under the condition. Further, regarding the timing of detecting the peak P (that is, the wave number counting timing), the detection may be sequentially performed from the deformation signal, or the voltage level data sampled over the unit measurement time may be entirely stored in the work memory (one of the RAM 23). ) May be detected collectively from data within the unit measurement time.

The control section 21 also functions as a pulse rate calculating means of the present invention, and calculates the pulse rate during dialysis of the patient 1 from the wave number counted by the wave number counting means. In the present embodiment, since the number of waves per minute is counted, the counting result becomes the pulse rate of the patient 1 as it is. Therefore, the pulse rate calculating means sets the counting result of the wave number counting means as the pulse rate during dialysis. In other words, the pulse rate calculating means calculates the pulse rate during dialysis by multiplying the counting result of the wave number by the coefficient 1. If the unit measurement time is out of one minute, the pulse rate calculating means calculates the pulse rate during dialysis by multiplying the count result of the wave number counting means by a coefficient corresponding to the unit measurement time.

The input device 24 is for inputting dialysis-related information such as personal information of the patient 1 related to dialysis to the control unit 21. For example, various information input such as a keyboard, a mouse, a scanner, a bar code reader, etc. It is composed of equipment.

The input / output interface 25 is for transmitting and receiving various information between the monitoring computer 6 and external devices. In the present embodiment, a deformation signal from the tube deformation measurement sensor 5 is received, and a pulse signal indicating the pulse rate during dialysis calculated by the control unit 21 (pulse rate calculation means) is output.

To perform dialysis treatment with the artificial dialysis system having such a configuration, first, the tube 2 is set on the tube deformation measuring sensor 5, and the sensor 5 is set in a detectable state. Since this tube 2 is previously filled with physiological saline, one end of the arterial tube 2a is then connected to the patient 1.
Venous tube 2 in the arteriovenous puncture of arteriovenous shunt
The other end of b is connected to the venous puncture part. In this way, when the tube 2 is connected, the pump 3 is operated to start introducing blood into the dialyzer 4, and
A dialysate supply device (not shown) is operated to start supplying the dialysate to the dialyzer 4. In this case, the blood in the blood circuit constituted by the tube 2 and the dialyzer 4 is maintained at an appropriate temperature by temperature control means (heater or the like) not shown. The blood led out of the body of the patient 1 by driving the pump 3 passes through the arterial tube 2a, and the dialyzer 4 removes waste and purifies the blood, and also removes excess water. The blood processed by the dialyzer 4 is returned to the patient 1 through the venous tube 2b.

During the blood purification process, the pulse measuring system, that is, the tube deformation measuring sensor 5 and the monitoring computer 6 continuously measure the pulse rate of the patient 1 during the dialysis treatment. . That is, as described above, the monitoring processing computer 6 acquires the deformation signal from the tube deformation measurement sensor 5 in conjunction with the start of the dialysis treatment, and determines the pulse rate during dialysis of the patient 1 based on the acquired deformation signal. calculate.

The calculated pulse rate during dialysis is output to the outside through the input / output interface 25 as a pulse signal. That is, the pulse signal is output to the outside one after another every time the unit measurement time elapses. This pulse signal is arbitrarily used by an external device. For example, by outputting this pulse signal to a recorder (not shown), the recorder continuously records the temporal change of the pulse rate for the patient 1 undergoing the dialysis treatment on a recording paper. Then, a medical worker such as a nurse can check the physical condition of the patient 1 by checking the time-dependent change of the recorded pulse rate during dialysis.
For example, the dialysis pulse rate at the confirmation time and the history of the dialysis pulse rate up to the pulse rate at that time can be confirmed at a glance. In this case, if the pulse rate during dialysis at the time of confirmation deviates from the normal value, the nurse or the like can immediately recognize that an abnormality has occurred. Furthermore, even if the pulse rate during dialysis at the time of confirmation is within the range of the normal value, if a rapid change in the pulse rate is observed, the patient 1 may have a sudden change in the state. Since the history of the pulse rate during dialysis is recorded on the recording paper, nurses and the like can detect this sudden change at an early stage.

When the recorder is arranged near the patient 1, the nurse or the like does not need to measure the pulse of the patient 1, so that the workability can be improved. Also, the actions performed by the patient 1 during the dialysis treatment, such as sleep, reading,
There is no hindrance to watching TV. Further, when the recorder is located at the nurse center, the workability can be further improved because the nurse or the like does not have to perform a tour for measuring the pulse.

As described above, in the above-described pulse measuring system, the number of waves per unit measurement time is counted from the deformation signal obtained by measuring the amount of deformation of the tube 2, and the pulse rate during dialysis of the patient 1 is calculated from the counted wave numbers. Therefore, the pulse rate can be continuously measured during the period in which the dialysis treatment is performed. Since the pulse rate can be continuously measured during the treatment period, a nurse or the like can quickly respond to a change in the state of the patient 1. Further, when measuring the pulse rate during dialysis, the patient 1 does not need to perform any special operation and only needs to undergo dialysis treatment. For this reason, in the patient 1, the actions such as sleep and reading during the dialysis treatment are not hindered by the pulse measurement, and the stress during the treatment can be reduced.

By the way, this pulse measuring system has been described in which the measured pulse rate is output as a pulse signal to an external device and used by the external device, but the present invention is not limited to this embodiment. . For example, the state of the patient 1 may be determined based on the measured pulse rate during dialysis, and a warning signal may be output when it is determined that there is an abnormality or a possibility of abnormality. Hereinafter, a second embodiment configured as above, that is, a pulse monitoring system will be described.

In the second embodiment, the configuration of the artificial dialysis system is the same as that of the first embodiment. In other words, the processing performed by the control unit 21 is different from that of the first embodiment. Hereinafter, the difference will be mainly described.

The dialysis treatment by the artificial dialysis system of this embodiment is the same as that of the first embodiment. Briefly, after the tube 2 is set on the tube deformation measuring sensor 5, one end of the arterial tube 2a is inserted into the arterial puncture portion of the arteriovenous shunt of the patient 1, and the other end of the venous tube 2b is inserted into the venous puncture portion. Connect to each. When the tube 2 is connected, the pump 3 is operated to start the introduction of blood to the dialyzer 4, and the dialysate supply device (not shown) is operated to start supplying the dialysate to the dialyzer 4.

During the period during which the dialysis treatment is performed,
The pulse monitoring system, that is, the tube deformation measuring sensor 5 and the monitoring processing computer 6 continuously calculate the pulse rate of the patient 1 during the dialysis treatment, and determine whether the calculated pulse rate during the dialysis is within a preset allowable fluctuation range. Monitor whether it is. If the pulse rate during dialysis is out of the allowable fluctuation range, a warning signal is output.

More specifically, the RAM 23 of the monitoring computer 6 stores allowable fluctuation range setting information for setting the allowable fluctuation range of the pulse rate. This allowable variation range setting information is a type of dialysis-related information input by the input device 24 (personal information input means), and is set for each dialysis patient 1. In the present embodiment, an allowable range for the degree of change in the pulse rate is set as allowable change range setting information. The degree of fluctuation of this pulse rate is
The rate of change with respect to the reference pulse rate. For example, when the reference pulse rate is 80, the degree of change corresponding to the pulse rate 70 is 0.875, and the degree of change corresponding to the pulse rate 90 is 1 .125. Therefore, as the allowable variation range setting information, the upper limit value and the lower limit value of the variation degree are stored in pairs.

In conjunction with the start of the dialysis treatment, the control section 21 functions as the wave number counting means of the present invention, and counts the number of waves per unit measurement time based on the deformation signal from the tube deformation measurement sensor 5. It also functions as a starting pulse rate calculating means, and calculates the starting pulse rate of the dialysis patient 1 at the start of dialysis from the counted wave numbers. Here, immediately after the start of the dialysis, there is a high possibility that the count value of the wave number is unstable, so the control unit 21 calculates the pulse rate at the start when the count value of the wave number becomes stable. Note that this starting pulse rate is RA
It is stored in a predetermined area of M23, and is appropriately referred to by the control unit 21.

After calculating the pulse rate at the start, the control unit 21
Functions as the wave number counting means of the present invention, and counts the number of waves per unit measurement time based on the deformation signal from the tube deformation measurement sensor 5, and also functions as the pulse rate calculation means during dialysis. The pulse rate during the dialysis of the dialysis patient 1 during the dialysis treatment is calculated from the above. Further, the control unit 2
Each time 1 calculates the pulse rate during dialysis, it functions as a fluctuation degree calculating means, and calculates the fluctuation degree of the pulse rate based on the measurement start time from the pulse rate during dialysis and the pulse rate at the start.

When the degree of fluctuation of the pulse rate is calculated, the control unit 2
Reference numeral 1 functions as a monitoring unit, and monitors whether or not the degree of change in the calculated pulse rate is within an allowable fluctuation range set in the RAM 23 in advance. That is, the control unit 21 determines whether or not the calculated degree of fluctuation is within the range from the upper limit to the lower limit stored as the allowable fluctuation range setting information. Then, when the degree of fluctuation of the pulse rate during dialysis falls outside the allowable fluctuation range, the control unit 21 functions as a warning signal output unit together with the input / output interface 25, and outputs a warning signal to the outside.

In the present embodiment, an alarm device (not shown) that is activated by receiving a warning signal is arranged at a nurse center. For this reason, when an abnormality is recognized in the patient 1, this alarm device is activated and a nurse at the nurse center is notified that the abnormality has occurred. Therefore, even if the state of the patient 1 changes suddenly, quick response is possible. When the alarm device is configured to output a wireless calling signal and a portable calling terminal that performs an alarm operation by receiving the calling signal is provided, the nurse or the like possesses the portable calling terminal. By doing so, it is possible to notify a nurse or the like that an abnormality has occurred regardless of the location, so that a more reliable response is possible.

In the second embodiment, the degree of fluctuation with respect to the reference pulse rate is used as the allowable fluctuation range setting information. However, the allowable fluctuation range setting information is information that can define the allowable range of the pulse rate during dialysis. Should be fine. For example, the upper limit value and the lower limit value of the allowable pulse rate may be used as the allowable fluctuation range setting information. Hereinafter, the second embodiment configured as described above will be described.
A modified example of the embodiment will be described.

In this modification, the upper limit value and the lower limit value of the pulse rate allowed as the allowable fluctuation range setting information constituting a part of the dialysis-related information are input to the input device 24 (personal information input means).
Is entered via The input upper limit value and lower limit value are stored in the RAM 23 as a pair. And the control unit 21
Functions as an allowable fluctuation range setting means, and sets an allowable fluctuation range of the pulse rate during dialysis based on the inputted upper limit value and lower limit value of the pulse rate. That is, the range from the upper limit value to the lower limit value of the pulse rate is set as the allowable variation range.

In conjunction with the start of the dialysis treatment, the control unit 21
It functions as the wave number counting means of the present invention, counts the wave number per unit measurement time based on the deformation signal from the tube deformation measurement sensor 5, and also functions as the pulse rate calculation means during dialysis, and performs dialysis from the counted wave number. The pulse rate of the dialysis patient 1 during the treatment is calculated. When calculating the pulse rate during dialysis, the control unit 21 functions as a monitoring unit, and monitors whether the calculated pulse rate during dialysis is within the allowable variation range. When the pulse rate during dialysis is out of the allowable fluctuation range, the control unit 2
1 functions as a warning signal output unit together with the input / output interface 25, and outputs a warning signal to the outside.

Also, in this modified example, the alarm device is activated by the reception of the warning signal, so that if an abnormality is recognized in the patient 1, the nurse or the like is notified that the abnormality has occurred.
Therefore, even if the state of the patient 1 changes suddenly, quick response is possible.

The first embodiment is a system for measuring the pulse rate during dialysis, and the second embodiment is a system for monitoring whether or not the measured pulse rate during dialysis is within an allowable range. However, in general, blood pressure is measured in addition to the pulse rate during the dialysis treatment. This is because patient 1 during dialysis treatment
This is because blood is circulating between the body of the patient and the dialyzer 4, and the blood pressure of the patient 1 may fluctuate rapidly. This blood pressure measurement is also performed by a medical staff such as a nurse at a frequency of about once every 30 minutes to 1 hour, and thus has the same problem as the pulse measurement. As described above, the tube deformation measurement sensor 5 is provided by focusing on the fact that there is a certain correlation between the blood pressure in the tube 2 (the internal pressure of the blood flow) and the amount of electricity based on the deformation of the tube 2. Things. Therefore, the blood pressure of the patient 1 can be measured based on the deformation signal from the tube deformation measurement sensor 5.
That is, the pulse rate and the blood pressure during the dialysis treatment can be simultaneously measured. Hereinafter, the third embodiment configured as described above,
That is, a pulse and blood pressure monitoring system will be described.

FIG. 6 is a diagram illustrating a schematic configuration of the artificial dialysis system according to the third embodiment. The first and second above
The main difference from the system of the embodiment is that a blood pressure measuring device 7 capable of separately measuring the blood pressure of the patient 1 is provided, and the measured blood pressure value measured by the blood pressure measuring device 7 is sent to the monitoring computer 6. I can input. The blood pressure measuring device 7 is used in a modification of the third embodiment described later. Other configurations are the same as those of the above-described embodiments.

The monitoring system according to the third embodiment, that is,
Tube deformation measuring sensor 5 and monitoring processing computer 6
First, an allowable fluctuation range of the pulse rate and an allowable fluctuation range of the systolic blood pressure are set for each dialysis patient. Then, at the start of the dialysis treatment, a deformation signal from the tube deformation measurement sensor 5 is obtained, and a start pulse rate and a start tube diameter at the start of dialysis are obtained. Thereafter, the pulse rate during dialysis and the tube diameter during dialysis are obtained based on the deformation signal, and the degree of fluctuation of the pulse rate is calculated from the pulse rate during dialysis and the pulse rate at the start, and the tube diameter during dialysis and the tube diameter at the start are obtained. The deformation ratio of the tube 2 is calculated from the above. Then, while monitoring whether or not the calculated degree of change of the pulse rate is within the allowable fluctuation range, it is also monitored whether or not the calculated deformation rate of the tube 2 is within the allowable fluctuation range. A warning signal is output on condition that at least one of them falls outside the allowable fluctuation range.

More specifically, the RAM 23 of the monitoring computer 6 stores allowable fluctuation range setting information for setting the allowable fluctuation range of the pulse rate and the allowable fluctuation range of the systolic blood pressure. In the present embodiment, the allowable range of the degree of change in the pulse rate and the allowable range of the deformation ratio of the tube 2 are stored as the allowable range. This allowable variation range setting information is a type of dialysis-related information input by the input device 24 as personal information input means,
It is set every time.

In conjunction with the start of the dialysis treatment, the control unit 21
While functioning as the wave number counting means of the present invention and counting the number of waves per unit measurement time based on the deformation signal from the tube deformation measurement sensor 5, it also functions as the starting pulse rate calculation means, and performs dialysis from the counted wave number. The start pulse rate of the dialysis patient 1 at the start is calculated. The calculated start pulse rate is stored in a predetermined area of the RAM 23. After calculating the pulse rate at the start, the control unit 21 functions as a wave number counting means, counts the wave number per unit measurement time based on the deformation signal from the tube deformation measuring sensor 5, and calculates the pulse rate during dialysis. And calculates the pulse rate during dialysis of the dialysis patient 1 during the dialysis treatment from the counted wave number. Further, every time the pulse rate during dialysis is calculated, the control unit 21 functions as a fluctuation degree calculating unit, and calculates the fluctuation degree of the pulse rate based on the measurement start time from the pulse rate during dialysis and the pulse rate at the start. I do.

The control unit 21 also functions as a starting tube diameter acquisition means of the present invention, and determines the tube diameter in the expanding period at the start of dialysis based on the deformation signal from the tube deformation measuring sensor 5 at the start. Get as diameter. The acquired starting tube diameter is stored in a predetermined area of the RAM 23. If the tube diameter at the start is obtained, control unit 2
1 functions as a tube diameter obtaining means during dialysis, and obtains the tube diameter during the dialysis treatment during the dialysis treatment as the tube diameter during dialysis based on the deformation signal from the tube deformation measurement sensor 5. Every time the diameter of the tube during dialysis is acquired, the control unit 21 functions as a deformation ratio calculating unit, and calculates the deformation ratio of the tube 2 based on the measurement start time from the tube diameter during dialysis and the tube diameter at the start.

The diameter of the tube 2 is proportional to the pressure of the blood flowing in the tube 2, that is, the arterial pressure. Therefore, by acquiring the diameter of the tube 2, the arterial pressure of the patient 1 at that time can be known. In order to know the arterial pressure from the diameter of the tube 2, for example, the relationship between the pressure and the diameter of the liquid flowing in the tube 2 is measured in advance, and a conversion table based on the measurement result is stored in the ROM 22. The conversion table may be referred to the control unit 21 (starting tube diameter acquisition unit, dialysis tube diameter acquisition unit). And the diameter of the tube 2 is
, The deformation rate of the tube 2 indicates the rate of change in systolic blood pressure based on the start of dialysis.

After calculating the degree of change in the pulse rate and the deformation ratio of the tube 2, the control unit 21 functions as monitoring means, and the calculated degree of the change in the pulse rate and the deformation rate of the tube 2 are set to a predetermined allowable value. Monitor whether it is within the fluctuation range.
If at least one of the pulse rate fluctuation degree and the deformation ratio of the tube 2 is out of the predetermined allowable fluctuation range, that is, the pulse rate during dialysis or the systolic blood pressure during dialysis is changed to the pulse rate at the start of dialysis. If the number or systolic blood pressure value has changed more than the specified ratio, the control unit 21 functions as a warning signal output unit together with the input / output interface 25, and outputs a warning signal to the outside.

Also in the third embodiment, the alarm device is activated by receiving the warning signal, so that if an abnormality is found in the patient 1, the nurse or the like is notified that the abnormality has occurred. For this reason, it is not necessary to go around for pulse measurement and blood pressure measurement unlike the related art, and the workability can be improved. Further, if the condition of the patient 1 deteriorates, the condition is notified to a nurse or the like at that time, so that prompt response is possible. In this embodiment, since both the pulse rate and the blood pressure are continuously measured based on the deformation signal from the tube deformation measurement sensor 5, the action of the patient 1 during the dialysis treatment is not hindered. Therefore, stress of the patient 1 can be prevented.
Further, since the pulse measurement and the blood pressure measurement are performed by the control unit 21 based on the deformation signal from the tube deformation measurement sensor 5,
The device configuration can be simplified, and the device can be manufactured at low cost.

By the way, in the third embodiment, the abnormality of the patient 1 during the dialysis treatment is judged based on the fluctuation rate of the pulse rate and the deformation ratio of the tube 2, but the allowable fluctuation range of the pulse rate and the systolic blood pressure is determined. May be set by the pulse rate and the blood pressure value, and the abnormality of the patient 1 may be determined by comparing the dialysis pulse rate and the dialysis systolic blood pressure acquired during the dialysis treatment with the allowable fluctuation range. Hereinafter, a modified example of the third embodiment configured as described above will be described.

The monitoring system of this modification, that is, the tube deformation measuring sensor 5 and the monitoring computer 6 first determine the allowable fluctuation range of the pulse rate and the maximum allowable blood pressure range of the systolic blood pressure for each dialysis patient 1. Set by blood pressure value. And
During the dialysis treatment, a deformation signal from the tube deformation measurement sensor 5 is obtained, and the number of waves per unit measurement time is counted from the obtained deformation signal, and the pulse rate during dialysis of the dialysis patient 1 is calculated from the counted wave number. On the other hand, the systolic blood pressure value during dialysis is calculated from the acquired deformed signal. further,
Monitors whether the calculated dialysis pulse rate is within the permissible fluctuation range, monitors whether the calculated dialysis systolic value is within the permissible fluctuation range, and monitors at least the dialysis pulse rate and the dialysis systolic blood pressure value. A warning signal is output on the condition that one of them falls outside the allowable fluctuation range.

More specifically, the RAM 23 of the monitoring computer 6 stores allowable fluctuation range setting information for setting the allowable fluctuation range of the pulse rate and the allowable fluctuation range of the systolic blood pressure. In this modification, the allowable upper limit and the lower limit of the pulse rate and the allowable upper and lower limits of the systolic blood pressure are stored as the allowable variation range. This allowable variation range setting information is a type of dialysis-related information input by the input device 24 as personal information input means. Specifically, the actual measurement information separately measured by the blood pressure measurement device 7 or a nurse immediately before the start of dialysis. The pulse rate and the measured systolic blood pressure value are set by inputting through the input device 24. That is, the control unit 21 (allowable fluctuation range setting means)
Sets an upper limit value and a lower limit value of the pulse rate based on the input actually measured pulse rate, stores the upper limit value and a lower limit value in the RAM 23, and sets the upper limit value and the lower limit value of the systolic blood pressure based on the input measured systolic blood pressure value. It is stored in the RAM 23.

In connection with the start of the dialysis treatment, the control unit 21
While functioning as the wave number counting means of the present invention and counting the number of waves per unit measurement time based on the deformation signal from the tube deformation measurement sensor 5, it also functions as the pulse rate calculation means and determines the dialysis patient 1 from the counted wave number. Calculate the pulse rate during dialysis. Further, the control unit 21 functions as a systolic blood pressure value calculating unit of the present invention, and calculates a systolic blood pressure value during dialysis based on a deformation signal from the tube deformation measurement sensor 5. In addition,
The method of calculating the systolic blood pressure value during dialysis from the deformed signal may use the conversion table as described above or multiply the tube diameter (voltage value of the deformed signal) by a conversion correction coefficient.

Further, the control section 21 functions as the monitoring means of the present invention, and monitors whether or not the calculated pulse rate during dialysis and the systolic blood pressure value during dialysis are within the allowable fluctuation range stored in the RAM 23. When at least one of the pulse rate during dialysis and the systolic blood pressure value during dialysis is out of the allowable fluctuation range, the control unit 2
1 functions as a warning signal output unit together with the input / output interface 25, and outputs a warning signal to the outside.

Also in this modification, the pulse measurement and the blood pressure measurement during the dialysis treatment can be continuously and automatically performed, so that the work load on nurses and the like can be reduced, and the action of the patient 1 during the treatment can be prevented. There is no. Further, when an abnormality is recognized in the patient 1, the alarm device is activated to notify the nurse or the like that the abnormality has occurred, so that a quick response is possible.

Incidentally, the present invention is not limited to the above-described embodiment, and various modifications can be made based on the description in the claims.

For example, in each of the above-described embodiments, the change in the diameter of the tube 2 is obtained by measuring the change in the diameter of the tube 2 with the tube deformation measuring sensor 5. However, the present invention is not limited to this. The amount of deformation may be obtained by measuring the amount of change in the tube diameter at the position. Also, the gripper 2
9 is constituted by a groove having an open top surface having a width substantially equal to the tube diameter in the steady state and a height set to be equal to or larger than the tube diameter in the steady state, and fitting the tube 2 into the groove. The tube 2 may be positively expanded upward (toward the movable rod 28b) by an increase in the internal pressure of the blood flowing inside.

The above tube deformation measuring means only needs to detect the amount of deformation of the tube 2. For this reason, as the tube deformation measurement sensor, a measurement sensor including an arm (a kind of movable member) extending in the horizontal direction and a displacement detection element arranged at the base end of the arm may be used.
In this tube deformation measurement sensor, the arm is displaced in accordance with the deformation of the tube 2 by bringing the tip of the arm into contact with the upper end of the tube 2, and the displacement detection element detects the amount of displacement of the arm.

Further, regarding the tube deformation measuring means, a configuration other than the tube deformation measuring sensor can be adopted. For example, the tube deformation measuring means may be constituted by a pressure sensor. In this case, for example, a pressure sensor is arranged on the outer surface of the tube 2a, and the amount of deformation of the tube 2 due to the pressure fluctuation of blood passing through the tube 2a, that is, the amount of deflection or expansion / contraction of the tube side surface is detected by the pressure sensor. . Since the blood pressure in the tube 2a and the output from the pressure sensor have a correlation, the pulse rate and the blood pressure value can be obtained in the same manner as in the above embodiment. Further, the tube deformation measuring means may be constituted by a strain sensor. In this case, similarly to the pressure sensor, the strain sensor is connected to the tube 2a.
Is fixed to the outer surface of the tube, and deformation of the tube due to pressure from blood passing through the tube 2a is detected by a strain sensor. Also in this case, the amount of bending or expansion and contraction of the tube side surface is detected as the amount of deformation of the tube 2.

[0071]

According to the present invention as described above, the following effects can be obtained. That is, the number of waves per unit measurement time is counted from the deformation signal obtained by measuring the amount of deformation of the tube in the middle of the tube that sends blood to the dialyzer, and the pulse rate of the dialysis patient is obtained from the counted wave number. The pulse rate can be continuously measured over the period during which the treatment is being performed. Since the pulse rate can be continuously measured during the treatment period, the work load on the medical staff can be reduced, and changes in the patient's condition can be promptly dealt with. Further, in measuring the pulse rate, the patient does not need to perform any special operation and only needs to undergo dialysis treatment as usual. For this reason, a patient during a dialysis treatment, for example, sleep or reading, is not hindered by the pulse measurement, and the patient can also reduce stress during the treatment.

Further, an allowable variation range of the pulse rate is set for each dialysis patient, and the wave number per unit measurement time is obtained from the deformation signal obtained by measuring the deformation amount of the tube in the middle of the tube for sending blood to the dialyzer. Counting, calculating the pulse rate during dialysis of the dialysis patient from the counted wave number, monitoring whether the pulse rate during dialysis is within the allowable fluctuation range, and confirming that the pulse rate during dialysis is outside the allowable fluctuation range. If a warning signal is output for the condition, a warning signal is output if the patient's condition changes suddenly and is judged abnormal, so the pulse rate is continuously measured during the treatment period In addition, when the patient is abnormal, an alarm operation based on the alarm signal can be performed. For this reason, the work load of the medical staff can be reduced, and changes in the patient's condition can be responded quickly and reliably.

Further, an allowable variation range of the pulse rate and an allowable variation range of the systolic blood pressure are set for each dialysis patient, and the deformation amount of the tube is measured by measuring the deformation amount of the tube in the middle of the tube for sending blood to the dialyzer. After counting the number of waves per unit measurement time from the obtained deformed signal, while calculating the pulse rate during dialysis of the dialysis patient from the counted wave number, calculating the systolic blood pressure value during dialysis from the obtained deformed signal was calculated. While monitoring whether or not the pulse rate during dialysis is within the permissible fluctuation range, monitoring the calculated systolic blood pressure value during dialysis is within the permissible fluctuation range, at least one of the pulse rate during dialysis and the systolic blood pressure value during dialysis. If a warning signal is output under the condition that the value is out of the allowable fluctuation range, both the pulse rate measurement and the systolic blood pressure measurement during the dialysis treatment can be automatically performed continuously. . Therefore, the work load on the medical staff can be further reduced, and the stress on the patient can be further reduced.

[Brief description of the drawings]

FIG. 1 is a schematic configuration diagram of an artificial dialysis system.

FIG. 2 is a diagram illustrating a tube deformation measurement sensor.

FIG. 3 is a diagram illustrating a tube deformation measurement sensor.

FIG. 4 is a diagram illustrating a deformation signal during dialysis treatment.

FIG. 5 is a schematic configuration diagram of a computer for monitoring processing.

FIG. 6 is a schematic configuration diagram of an artificial dialysis system taking blood pressure measurement into account.

[Explanation of symbols]

 Reference Signs List 1 patient 2 tube 2a arterial tube 2b venous tube 3 pump 4 dialyzer 5 tube deformation measurement sensor 6 computer for monitoring and processing 7 blood pressure measurement device 11 case 12 deformation sensor 13 gripper 14 sensor case 15 movable rod 15a tip of movable rod Reference Signs List 16 displacement detection element 21 control unit 22 ROM 23 RAM 24 input device 25 input / output interface

 ────────────────────────────────────────────────── ─── Continued on the front page (72) Minoru Kataiki Inventor 2- 16-2 Noguchicho, Higashimurayama-shi, Tokyo F-term in Kisso Corporation Higashimurayama Works (reference) 4C017 AA08 AA10 AB10 AC02 BC11 BD06 FF15 4C077 AA05 BB01 DD21 DD30 EE01 HH03 HH13 HH18 HH21

Claims (11)

[Claims] 1. A wave number per unit measurement time is counted from a deformation signal obtained by measuring a deformation amount of a tube in the middle of a tube for sending blood to a dialyzer, and a pulse during dialysis of a dialysis patient is calculated from the counted wave number. A pulse measuring method in artificial dialysis, characterized by obtaining a number. 2. The artificial dialysis according to claim 1, wherein the counting of the wave number per unit measurement time is performed by counting the peak of the waveform corresponding to the systolic blood pressure of the patient over the unit measurement time. Pulse measurement method in. 3. The pulse measuring method in artificial dialysis according to claim 1, wherein the measuring point of the tube is set near a connecting needle inserted into the arterial puncture part. 4. An allowable variation range of a pulse rate is set for each dialysis patient, and a wave number per unit measurement time is obtained from a deformation signal obtained by measuring a deformation amount of the tube in the middle of a tube for sending blood to a dialyzer. Counting, calculating the pulse rate during dialysis of the dialysis patient from the counted wave number, monitoring whether the pulse rate during dialysis is within the allowable fluctuation range, and confirming that the pulse rate during dialysis is out of the allowable fluctuation range. A pulse monitoring method in dialysis, wherein a warning signal is output for a condition. 5. An allowable fluctuation range of a pulse rate and an allowable fluctuation range of a systolic blood pressure are set for each dialysis patient, and a deformation signal is obtained by measuring a deformation amount of the tube in the middle of a tube for sending blood to a dialyzer. After counting the number of waves per unit measurement time from the obtained deformed signal, the dialysis pulse rate of the dialysis patient was calculated from the counted wave number, and the systolic blood pressure value during dialysis was calculated from the obtained deformed signal. While monitoring whether or not the pulse rate during dialysis is within the permissible fluctuation range, monitoring whether the calculated systolic blood pressure value during dialysis is within the permissible fluctuation range, at least one of the pulse rate during dialysis and the systolic blood pressure value during dialysis is performed. A method for monitoring a pulse and blood pressure in artificial dialysis, wherein a warning signal is output under a condition that the pulse falls outside an allowable fluctuation range. 6. A tube deformation measuring means which is arranged in the middle of a tube for sending blood to a dialyzer and measures a deformation amount of the tube and outputs a deformation signal, based on a deformation signal output by the tube deformation measuring means. Wave number counting means for counting the wave number per unit measurement time, and pulse rate calculation means for calculating the pulse rate during dialysis of the dialysis patient from the wave number counted by the wave number counting means, the artificial dialysis characterized by comprising Pulse measurement system. 7. The apparatus according to claim 6, wherein the wave number counting means counts the number of waves per unit measurement time by counting the peak of the waveform corresponding to the systolic blood pressure of the patient over the unit measurement time. The pulse measuring system in the artificial dialysis according to [1]. 8. A tube deformation measuring means which is arranged in the middle of a tube for sending blood to a dialyzer, measures a deformation amount of the tube and outputs a deformation signal, and based on a deformation signal output by the tube deformation measuring means. Wave number counting means for counting the number of waves per unit measurement time, a starting pulse rate calculating means for calculating a starting pulse rate of a dialysis patient at the start of dialysis from the wave numbers counted by the wave number counting means, and a wave number counting means Pulse rate calculating means for calculating a pulse rate during dialysis of a dialysis patient during dialysis treatment from a wave number counted by the dialysis treatment, and a pulse rate fluctuation based on the measurement start pulse rate based on the pulse rate during dialysis and the pulse rate at start Monitoring the degree of fluctuation of the pulse rate calculated by the fluctuation degree calculating means for calculating the degree and the pulse fluctuation amount calculating means to determine whether the degree of fluctuation is within a predetermined allowable fluctuation range. Pulse monitoring system in dialysis, characterized in that it comprises a monitoring unit, and the warning signal output means for outputting a warning signal when the variation degree of the number in the dialysis pulse is out of the allowable variation range, the. 9. A tube deformation measuring means disposed in the middle of a tube for sending blood to a dialyzer, for measuring a deformation amount of the tube and outputting a deformation signal, and personal information input means for inputting dialysis-related information of a dialysis patient. A wave number counting means for counting a wave number per unit measurement time based on a deformation signal output by the tube deformation measuring means; and a pulse for calculating a pulse rate during dialysis of the dialysis patient from the wave number counted by the wave number counting means. Number calculation means, allowable fluctuation range setting means for setting an allowable fluctuation range of the pulse rate during dialysis based on the dialysis-related information input by the personal information input means, and the pulse rate during dialysis calculated by the pulse rate calculation means A monitoring means for monitoring whether or not the blood pressure is within the allowable fluctuation range; and a warning for outputting a warning signal on condition that the pulse rate during dialysis is out of the allowable fluctuation range. A pulse output system for artificial dialysis, comprising: a signal output unit. 10. A tube deformation measuring means which is arranged in the middle of a tube for sending blood to a dialyzer, measures a deformation amount of the tube and outputs a deformation signal, and based on a deformation signal output by the tube deformation measuring means. A wave number counting means for counting the number of waves per unit measurement time, a starting pulse rate calculating means for calculating a starting pulse rate of a dialysis patient at the start of dialysis from the wave number counted by the wave number counting means, and a wave number counting means. Means for calculating a pulse rate during dialysis of a dialysis patient during a dialysis treatment from the counted wave number; a pulse rate during dialysis; and a degree of fluctuation of the pulse rate based on the measurement start pulse rate based on the pulse rate during dialysis and the start pulse rate Means for calculating the degree of change, and a tube in the diameter expansion period at the start of dialysis based on the deformation signal output by the tube deformation measuring means. A starting tube diameter obtaining means for obtaining a tube diameter as a starting tube diameter; and obtaining a tube diameter during a dialysis treatment as a tube diameter during dialysis based on a deformation signal output by the tube deformation measuring means. Means for obtaining the tube diameter during dialysis, means for calculating the deformation ratio of the tube based on the start of measurement from the tube diameter during dialysis and the tube diameter at the start, and the change in the pulse rate calculated by the degree of change calculation means Monitoring means for monitoring whether the degree and the deformation ratio of the tube calculated by the deformation ratio calculation means are within a predetermined allowable fluctuation range; and at least one of the degree of fluctuation of the pulse rate and the deformation ratio of the tube is predetermined. A warning signal output means for outputting a warning signal on condition that the outside of the allowable fluctuation range. Monitoring system of that pulse and blood pressure. 11. A tube deformation measuring means disposed in the middle of a tube for sending blood to a dialyzer, for measuring a deformation amount of the tube and outputting a deformation signal, and personal information inputting means for inputting dialysis-related information of a dialysis patient. A wave number counting means for counting a wave number per unit measurement time based on a deformation signal output by the tube deformation measuring means; and a pulse for calculating a pulse rate during dialysis of the dialysis patient from the wave number counted by the wave number counting means. Number calculating means, systolic blood pressure value calculating means for calculating a systolic blood pressure value during dialysis based on the deformation signal output by the tube deformation measuring means, and dialysis based on the dialysis-related information input by the personal information input means. An allowable fluctuation range setting means for setting an allowable fluctuation range of the medium pulse rate and an allowable fluctuation range of the systolic blood pressure value during dialysis; and a pulse rate calculating means. Monitoring means for monitoring whether the calculated dialysis pulse rate and the dialysis systolic value calculated by the systolic blood pressure calculation means are within the permissible fluctuation range; and at least one of the dialysis pulse rate and the dialysis systolic blood pressure value. And a warning signal output unit that outputs a warning signal on condition that the value of the blood pressure falls outside the allowable fluctuation range.