JP2002159572A - Continuous chemical injector - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a non-cylindrical and compact continuous chemical injector having high portability. SOLUTION: In this continuous chemical injector, chemicals are filled in the inner part of a balloon, and the contracting force of the balloon is used as a driving force for feeding. Thus injector comprises a wall attached so as to restrain the expanding dimension in the expanding process of balloon for filling the chemicals to the outside of the balloon.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a continuous infusion device for infusion of anesthesia and analgesics as a countermeasure for pain in postoperative patients and for use in arterial infusion chemotherapy. The present invention also relates to a device used for continuous administration of various other drugs.

[0002]

2. Description of the Related Art A disposable continuous drug injector is used for continuous administration of an analgesic for postoperative pain control and continuous injection of an anticancer drug. In the past, mechanical continuous drug injectors were often used.However, due to the fact that the equipment is heavy and practically stationary, and the number of equipment installed in hospitals is limited, etc. In such a case, a disposable continuous drug dispenser with good portability and low cost has come to be widely used. Many of the disposable types are a continuous drug injector (JP-A-6-296688) in which a drug is injected into a cylindrical balloon and the contraction force of the balloon is used as a driving force.

[0003] The continuous drug injector is a drug inlet and a balloon,
In general, it comprises a chemical solution outlet, a housing covering the balloon, a liquid sending tube, and a flow control tube. When using a continuous drug solution injector, a drug solution is first injected into the balloon from a drug solution inlet to expand the balloon. The expanded balloon pressurizes the drug solution by the contraction force of the material, and this becomes a driving force for sending the drug solution. The flow rate is regulated by a flow control tube. When the drug solution filled in the balloon is exhausted, the balloon returns to the shape before the injection of the drug solution, the contraction force is lost, and the solution sending ends.

[0004] The external appearance of the main body of the balloon-type continuous drug injector is generally cylindrical with a length of 20 cm or more. This is because the longer the balloon is, the smaller the change in pressure generated by the balloon even if the internal volume of the balloon changes during the process of sending the drug solution, and the longer the balloon can be delivered at the set flow rate. One of the features of the disposable continuous infusion device is that it is portable, but in fact, a special pochette is included because the elongated housing of the continuous solution infusion device cannot be stored in the patient's pocket. I have.

[0005] Further, there is a problem in that when placed on the bedside due to the cylindrical shape, it rolls down unsteadily and is often unsanitary. Further, a balloon having a small diameter is selected in order to send the entire amount of the filled chemical at a flow rate according to a set value. However, as shown in FIG. However, there is a problem that the concentration of the drug in the body temporarily rises due to a sudden increase in sex, and the patient's consciousness is diminished.

In addition to the balloon type, a spring type (JP-A-7-5136)
No. 7) and a negative pressure type (Japanese Utility Model Laid-Open No. 5-20751). In the spring type, since the spring has a cylindrical shape, the appearance is also cylindrical and has the above-mentioned problem. In addition, since a storage portion for the spring is required, there is a problem that the size is increased. (The size of the balloon type is 100 ml and the size is only 60 ml.) Further, since a metal spring is provided, there is a problem that the weight is heavier than that of the balloon type.

Further, since a spring is used as a power source, the force is unavoidably attenuated in the process of expanding the spring, and there is a problem that the pressure gradually decreases as shown in FIG. The negative pressure type has the same cylindrical shape as the balloon type and has the problem of rolling down at the bedside, and the necessity of providing a negative pressure generating part increases the size. Some patients felt uncomfortable. Further, as shown in FIG. 1, when the filling amount of the drug solution is small, the pressure decreases gradually, so that the ratio of the amount that can be administered at a set flow rate of the filled drug solution is small compared to other methods. There was a point.

[0008]

SUMMARY OF THE INVENTION An object of the present invention is to provide a non-cylindrical, compact and highly portable continuous liquid injector.

[0009]

In other words, the present invention provides (1) a liquid medicine filling device in which the inside of a balloon is filled with a liquid medicine, and the contraction force of the balloon is used as a driving force for liquid supply. A continuous liquid injector, wherein a wall for restricting the inflation dimension during the inflation process of the balloon is provided in the housing; (2) the continuous liquid injector according to (1), wherein the housing has a flat shape; (3) the continuous drug injector according to (2), wherein the flat shape is a flat rectangular parallelepiped;
The liquid medicine continuous injector according to any one of (1) to (3), wherein the minimum width of the housing is 50 to 80% of the diameter of the balloon when the balloon is freely inflated when the maximum amount of the predetermined amount of injection is filled.
(5) The longitudinal elastic modulus of the balloon material is 0.1 to 1.0 kg.
/ Mm ^{2. The} continuous liquid injector according to any one of (1) to (4).

[0010]

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS The present invention will be described below in detail with reference to the drawings. FIG. 2 shows a continuous drug injector which is an outline of the present invention.
The drug solution continuous infusion device according to the present invention basically includes a balloon (1) that stores a drug solution and serves as a driving force for sending the solution, a balloon gripper (2) that fixes the balloon, a housing (3) that protects the balloon, and a syringe. And a liquid feed tube (5) through which a liquid can be injected.

[0011] The balloon (1) is selected from elastic materials such as natural rubber, silicone rubber, and isobutyl rubber.
A material that is harmless to the living body and has no eluate to the drug solution is desirable. The shape of the balloon is not particularly limited, but is preferably a cylindrical shape having one end closed. Although the diameter of the balloon depends on the dimensions of the housing to be used, it is preferably 5 to 20 mm before inflation in order to maintain a high pressure with a small amount of the liquid medicine filled. The balloon is hardly ruptured even when it comes into contact with the partition wall of the housing (3), and in order to generate an appropriate pressure, the elastic modulus of the balloon is 0.1 to 1.0K.
g / mm ² .

FIG. 1 shows a pressure change during liquid feeding when the same flow control pipe is used. The pressure change may be regarded as a flow rate change. When comparing the present product with other continuous drug solution injectors, the product of the present invention is a balloon type, but does not show a rapid pressure rise even if the filling amount of the drug solution is small, and is compared with a negative pressure type. It can be seen that the pressure decrease in the state where the filling amount is small is steep, and the filled chemical can be efficiently sent at the set flow rate.

The balloon gripper (2) is formed of a resin inert to a chemical such as polyethylene, fluororesin, ABS resin and the like. Considering price and moldability, polypropylene resin is most desirable. It is desirable that the mounting portion of the balloon (1) be designed in a rib shape so as to be easily fixed. The balloon gripper (2) is provided with a chemical solution outlet (6) communicating with the liquid feed tube (5).

The housing (3) is preferably formed by blow molding, but may be formed by injection molding or the like. It is desirable that the inner surface of the housing (3) be smooth so as not to cause rupture of the balloon. It is desirable that the material is transparent and a scale is provided to confirm the state of the balloon and the remaining amount of the chemical solution in the balloon. The housing (3) is desirably a flat rectangular parallelepiped, and the shortest side length is designed to be 50 to 80% of the diameter when the balloon is freely inflated by injecting 100% of the filling amount into the balloon. desirable.

By restricting the free inflation of the balloon by the housing (3), as shown in FIG. 1, the pressure of the balloon rapidly rises in a state where the remaining amount of the drug solution, which has been a problem of the balloon type, is small. This solves the problem that the flow rate becomes larger than the set flow rate.
This is because the pressure is applied compared to the state when the balloon is freely inflated because the expansion of the balloon is suppressed by the housing when the amount of the liquid medicine is large and the pressure is higher than usual. This is because the pressure does not increase in a state where the filling amount is small. Accordingly, the housing (3) may have any shape as long as it suppresses the free inflation of the balloon. For example, the housing (3) may have a cross-sectional shape such as a figure 8 with a concave center as shown in FIG. 3 or a streamline flat housing as shown in FIG. good. In consideration of portability, it is desirable to make the size such that it does not fall from the bedside and fits in the pocket, and the thickness of the outer dimension is 30 mm or less.

The liquid injection port (4) is desirably shaped so that a syringe can be connected thereto, and is preferably a luer type in consideration of pressure resistance. One-way valve (7) at the inlet to prevent backflow of the contents of balloon (1)
Is desirably attached. Liquid sending tube (5)
The inner diameter of φ0.05 ~ 2 to prevent the tube from kinking
mm. In addition, liquid sending tube (5)
It is preferable that the material used in the first step is a transparent material so that the inner surface can be observed. Further, it is desirable that kink resistance is good and there is little eluted material, and it is desirable that the resin be a vinyl chloride resin, a polyurethane resin, or the like.

Next, an actual method of use will be described. First, a drug solution is injected into the balloon (1) from the drug solution inlet (4) using a syringe. Since the one-way valve (7) is attached to the chemical inlet (4), the chemical in the balloon (1) does not protrude from the chemical inlet. When a drug solution is injected into the balloon (1), the balloon (1) expands. The balloon (1) expands while contacting the inner wall of the housing. Pressure is applied to the drug solution in order to cause the balloon to deflate, and this is the power for feeding the solution.

[0018]

According to the present invention, since the housing has a flat shape instead of a cylindrical shape, even if it is placed on a flat part such as a desk, the housing does not roll down like a cylindrical continuous liquid injector and is safe. In addition, since it can be stored in a pocket of a normal size, the portability is good, the appearance is inconspicuous at all, and the patient can carry it easily. Because the housing has a structure that suppresses the outside of the balloon and compensates for the pressure, a problem with the conventional balloon-type continuous drug solution injector is that the flow rate rises rapidly with a small amount of drug solution filled. There is no point and the flow rate accuracy is good.

[Brief description of the drawings]

FIG. 1 is a graph showing measured changes in generated pressure in a process of feeding a product of the present invention and another continuous drug injector.

FIG. 2 shows an embodiment of the present invention.

FIG. 3 shows an embodiment of the present invention.

FIG. 4 shows an embodiment of the present invention.

[Explanation of symbols]

 DESCRIPTION OF SYMBOLS 1 Balloon 2 Balloon gripper 3 Housing 4 Chemical liquid inlet 5 Liquid supply tube 6 Chemical liquid outlet 7 One-way valve

Claims (5)

[Claims] Claims: 1. In a continuous drug injector in which a drug solution is filled in a balloon and a contraction force of the balloon is used as a driving force for feeding a liquid, a wall for restricting an inflation dimension in a process of inflation of the balloon for filling a drug solution outside the balloon. Is continuously provided in the housing. 2. The housing according to claim 1, wherein said housing has a flat shape.
The continuous drug injector according to the above. 3. The continuous injector according to claim 2, wherein the flat shape is a flat rectangular parallelepiped. 4. The diameter of the balloon at free inflation when the minimum width of the housing is filled to the maximum of a predetermined injection volume.
The continuous drug injector according to any one of claims 1 to 3, wherein the concentration is from 80% to 80%. 5. The balloon material has a longitudinal elastic modulus of 0.1 to less than 0.1.
1.0 kg / mm ² or of liquid infusion device of claim 1, wherein a.