JP2002119853A - Treatment agent of medical waste liquid - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a treatment agent of a medical waste liquid which has small degradation of water absorption performance due to concentration of electrolytes and can solidify the medical waste liquid even by a small quantity thereof. SOLUTION: The processing agent of the medical waste liquid contains a water-absorptive material composed of 5 to 60 wt.% nonion type water- absorptive resin and 95 to 40 wt.% of ion type water-absorptive resin.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

TECHNICAL FIELD The present invention relates to a medical waste liquid treating agent. More specifically, the present invention relates to a medical waste liquid treating agent effective for solidifying medical waste liquid.

[0002]

2. Description of the Related Art In recent years, waste liquid discharged from various industrial fields has been increasing steadily. In particular, medical waste fluids containing body fluids and disinfecting alcohol, etc. are collected in waste containers and then discharged to a septic tank after incineration or chemical treatment to prevent infectious diseases for medical workers and waste disposal companies. I have. However, in either case, if the treatment is performed in a liquid state, there is a risk of secondary infection due to breakage of the waste container or scattering of the liquid. Therefore, treatment after solidifying the medical waste liquid is desired.

[0003] As a waste liquid treatment agent for solidifying medical waste liquid,
There has been known a gelling material for medical waste in which a water-absorbing material made of a powdery or granular water-absorbing resin is wrapped in a water-disintegrable paper or a water-soluble film (Japanese Patent Application Laid-Open No. 6-216). . However, as the water-absorbing resin, a water-absorbing resin such as a partially hydrolyzed cross-linked polyacrylamide, a cross-linked acrylic acid-acrylic amide copolymer, or a cross-linked polyacrylic acid (salt) is used. . Since the water absorbing ability of these water absorbing resins utilizes the osmotic pressure caused by the difference in ion concentration, for example, Ca ²⁺ or Mg
^For a waste liquid containing ions such as ²⁺ , the water absorbing ability of the water-absorbing resin is reduced, the solidification time is prolonged, and it is necessary to use a large amount of resin.

Further, in order to prevent the water absorbing ability of the water absorbing resin from being lowered by the electrolyte, a waste liquid treating agent using a water absorbing resin in combination with a chelating agent or an ion exchange resin for lowering the strength of the electrolyte has been proposed (Japanese Patent Application Laid-Open No. HEI 9-260,1972). 11-169451). However, depending on the concentration of the electrolyte, the water absorbing ability of the water absorbing resin is reduced. In addition, the inside of the packaging container is divided into a plurality of rooms, and it is necessary to separately accommodate a water-absorbing resin, a chelating agent, and an ion-exchange resin.

Further, as a resin having a constant water absorption ability regardless of the concentration of the electrolyte, a waste liquid treating agent containing a crosslinked product of N-vinylcarboxylic acid amide alone or a copolymer has been proposed (JP-A-11-504). No.). However,
N-vinylcarboxylic acid amide homopolymer or copolymer crosslinked product has a low water absorbing ability, so that it is necessary to use a large amount of resin in order to solidify the waste liquid.

[0006]

SUMMARY OF THE INVENTION An object of the present invention is to provide a medical waste liquid treating agent capable of hardening a medical waste liquid even in a small amount, with little decrease in water absorption ability due to the concentration of an electrolyte.

[0007]

Means for Solving the Problems The present inventors have made intensive studies to solve the above-mentioned problems, and as a result, a medical waste liquid treating agent comprising a water-absorbing material containing a specific amount of a specific water-absorbing resin has been developed. The present inventors have found that a decrease in water absorption capacity due to the concentration of electrolyte in the solution is small and that a small amount of medical waste liquid can be solidified, and the present invention has been completed. That is, the present invention provides a nonionic water-absorbent resin 5 to 60% by weight and an ionic water-absorbent resin 9
The present invention relates to a medical waste liquid treating agent containing a water-absorbing material comprising 5 to 40% by weight.

[0008]

BEST MODE FOR CARRYING OUT THE INVENTION The medical waste liquid treating agent of the present invention contains a water-absorbing material composed of a specific amount of a nonionic water-absorbing resin and a specific amount of an ionic water-absorbing resin. More specifically, the medical waste liquid treating agent of the present invention uses a nonionic water-absorbing resin having a small decrease in water absorption ability due to electrolyte concentration and an ionic water-absorbing resin having excellent water absorption ability and water absorption rate in a specific ratio. Thereby, the decrease in water absorption capacity due to the concentration of the electrolyte in the medical waste liquid is small, and the medical waste liquid can be solidified with a small amount.

The content of the nonionic water-absorbing resin used in the present invention is 5 to 60% by weight, preferably 10 to 40% by weight, based on the total weight of the water-absorbing material. When the content of the nonionic water-absorbing resin is less than 5% by weight, Ca ²⁺
For a waste liquid containing ions such as Mg and Mg ²⁺ , the water absorption capacity is reduced, and the solidification time is prolonged or solidification cannot be performed. When the content of the nonionic water-absorbing resin exceeds 60% by weight, it is effective for waste liquid containing ions, but the water absorbing ability of the entire water-absorbing material is reduced.

The nonionic water-absorbing resin is not particularly limited, but is preferably prepared by reacting a polyalkylene oxide and a polyol with an isocyanate compound from the viewpoint of a short setting time and excellent strength and stability of the obtained gel. The modified polyalkylene oxide obtained by the above method is suitably used.

Examples of the polyalkylene oxide include polyethylene oxide, polypropylene oxide, ethylene oxide / propylene oxide copolymer,
Examples thereof include polybutylene oxide and a mixture thereof.

As the polyol, an organic compound having two hydroxyl groups (—OH) in the same molecule, for example, ethylene glycol, propylene glycol, 1,3-butanediol, 1,4-butanediol, 1,5- Examples include pentanediol, hexylene glycol, octylene glycol, glyceryl monoacetate, glyceryl monobutyrate, 1,6-hexanediol, and 1,9-nonanediol.

The above-mentioned isoanate compound includes an organic compound having two or more isocyanate groups in the same molecule,
For example, dicyclohexylmethane-4,4'-diisocyanate (HMDI), xylylene diisocyanate (XDI), 4,4'-diphenylmethane diisocyanate (MDI), 1,6-hexamethylene diisocyanate (HDI), 1,8-dimethylbenzol −2,4
-Diisocyanate and 2,4-tolylene diisocyanate (TDI).

The polyalkylene oxide and the diol may be reacted with the isocyanate compound in a solution using an appropriate solvent, in a dispersed state, or in a powder or solid state. After mixing, a method in which the mixture is heated to a predetermined temperature to cause a reaction can be used. From the viewpoint of industrial implementation, a method in which each raw material is continuously supplied in a molten state, and mixed and reacted in a multi-screw extruder is preferable.

The nonionic water-absorbing resin thus obtained is usually obtained in the form of pellets, sheets, films and the like. The obtained nonionic water-absorbent resin can be used in the form of these pellets, sheets, films, etc., but in the present invention, the solidification time is short, and from the viewpoint of easy mixing with the ionic water-absorbent resin, It is preferable to use it after pulverizing with a pulverizer or the like. The method of pulverizing the nonionic water-absorbing resin is not particularly limited,
Freezing and pulverization with liquid nitrogen is preferable to prevent fusion due to heat generated by shearing during pulverization. The median particle size of the pulverized nonionic water-absorbent resin is 100 to 600 μm, preferably 2 to 600 μm.
It is preferable to adjust the thickness to 00 to 500 μm. If the nonionic water-absorbent resin has a median particle size of less than 100 μm, it is not preferable because the water-absorbing resin is apt to form.
The median particle size of the nonionic water-absorbing resin is 600 μm.
When it exceeds, it is not preferable because the water absorption rate becomes low.
Here, the median particle size of the nonionic water-absorbing resin can be easily adjusted to the above range by pulverization and classification.

The content of the ionic water-absorbing resin used in the present invention is 95 to 40% by weight, preferably 90 to 60% by weight, based on the total weight of the water-absorbing material. When the content of the ionic water-absorbing resin exceeds 95% by weight, Ca ²⁺ or M
For a waste liquid containing ions such as g ²⁺ , the water absorption capacity is reduced, and the solidification time is prolonged or solidification cannot be performed. When the content of the ionic water-absorbing resin is less than 40% by weight, it is effective for waste liquid containing ions, but the water absorbing ability of the entire water-absorbing material is reduced.

The ionic water-absorbing resin is not particularly limited, and examples thereof include crosslinked polyacrylates, crosslinked starch-acrylate graft copolymers, crosslinked isobutylene-maleic anhydride copolymers, and the like. A water-absorbing resin is exemplified. Among them, a crosslinked polyacrylate is preferably used from the viewpoint of low production cost and high water absorption.

The method for producing the ionic water-absorbing resin is not particularly limited, and includes various generally known polymerization methods such as a reversed-phase suspension polymerization method and a solution polymerization method. For example, the polyacrylate cross-linked product is produced by an inverse suspension polymerization method using a radical polymerization initiator in a hydrocarbon solvent in the presence of a surfactant in an aqueous solution of acrylic acid neutralized with an alkali metal. can do.

Examples of the surfactant include sorbitan fatty acid esters, polyglycerin fatty acid esters,
Sucrose fatty acid ester, sorbitol fatty acid ester,
Nonionic surfactants such as polyoxyethylene alkyl phenyl ether and hexaglyceryl monobeherate;
Anionic surfactants such as fatty acid salts, alkyl benzene sulfonates, alkyl methyl taurates, polyoxyethylene alkyl phenyl ether sulfates, and polyoxyethylene alkyl ether sulfonates can be mentioned.

Examples of the radical polymerization initiator include water-soluble radical polymerization initiators such as potassium persulfate, ammonium persulfate and sodium persulfate; and oil-soluble radical polymerization initiators such as benzoyl peroxide and azobisisobutyronitrile. And the like.

Examples of the hydrocarbon solvent include n
Aliphatic hydrocarbons such as hexane, n-heptane and ligroin; alicyclic hydrocarbons such as cyclopentane, methylcyclopentane, cyclohexane and methylcyclohexane;
Examples thereof include aromatic hydrocarbons such as benzene, toluene, and xylene.

The aqueous acrylic acid solution, surfactant, radical polymerization initiator and the like neutralized by the alkali metal are heated in a hydrocarbon solvent with stirring to obtain a water-in-oil system.
By performing reverse phase suspension polymerization, acrylic acid neutralized with an alkali metal is polymerized, and a bead-like polymer in which a part of the generated polymer is self-crosslinked is obtained. Although this polymer exhibits water absorption, it has a low degree of crosslinking, and therefore it is preferable to add a crosslinking agent to carry out a crosslinking reaction.

Examples of the crosslinking agent include di- or tri (meth) acrylates of polyols such as ethylene glycol, propylene glycol, trimethylolpropane, and polyglycerin; and polyols such as maleic acid and fumaric acid. Unsaturated polyesters obtained by reacting with saturated acids; bisacrylamides such as N, N'-methylenebisacrylamide; di- or tri (meth) acrylic acid obtained by reacting polyepoxide with (meth) acrylic acid Esters; di (meth) acrylate carbamyl esters obtained by reacting polyisocyanates such as tolylene diisocyanate and hexamethylene diisocyanate with hydroxyethyl (meth) acrylate; allylated starch, allylated cellulose, diallyl phthalate , Compounds having two or more polymerizable unsaturated groups such as divinylbenzene; diglycidyl ether compounds such as (poly) ethylene glycol diglycidyl ether and (poly) glycerin diglycidyl ether; haloepoxy compounds such as epichlorohydrin and epibromhydrin; Compounds having two or more reactive functional groups such as isocyanate compounds such as 2,4-tolylene diisocyanate and hexamethylene diisocyanate can be exemplified.

The thus-obtained slurry containing the crosslinked polyacrylate is a solution in which the crosslinked polyacrylate dispersed in the mixed solvent of the hydrocarbon solvent and water is dispersed. By drying the slurry containing the crosslinked polyacrylate, a crosslinked polyacrylate can be produced.

The median particle size of the ionic water-absorbing resin is as follows:
Those having a thickness of 100 to 600 μm, preferably 200 to 500 μm are suitably used. When the median particle diameter of the ionic water-absorbing resin is less than 100 μm, it is not preferable because mamako is likely to be generated during water absorption. On the other hand, if the median particle diameter of the ionic water-absorbing resin is more than 600 μm, the water absorption rate is undesirably low. Here, the median particle size of the ionic water-absorbent resin can be easily adjusted by the number of rotations of stirring and the amount of the surfactant used when producing the ionic water-absorbent resin.

The water absorbing material constituting the medical waste liquid treating agent of the present invention can be produced by mixing the nonionic water absorbing resin and the ionic water absorbing resin. The mixing method is not particularly limited, and can be easily mixed using a Nauta mixer, a Henschel mixer, or the like, which is used for normal powder mixing. The obtained water-absorbent material can be used as it is as the medical waste liquid treating agent of the present invention. Also, if necessary, natural water-absorbing materials such as pectin and peat moss, inorganic water-absorbing materials such as silica gel, bentonite, zeolite, calcium silicate and talc, bactericides, antibacterial agents, fungicides, deodorants, and fragrances And the like may be mixed with the obtained water-absorbing material, or may be mixed at the same time when the water-absorbing material is produced.

The amount of the medical waste liquid treating agent used depends on the kind of the medical waste liquid, but is usually 5 to 5 per liter of the medical waste liquid.
0 g. If the amount of the medical waste liquid treating agent is less than 5 g, it takes a long time to solidify and the obtained solid is soft, and unabsorbed medical waste liquid or solid may be scattered from the container, which is not preferable. If the amount of the medical waste liquid treating agent exceeds 50 g, the amount of the unused medical waste liquid treating agent increases, which is not economical.

The method for using the medical waste liquid treating agent is as follows.
There is no particular limitation, and the method of adding the medical waste liquid treating agent of the present invention to an appropriate container containing the medical waste liquid and mixing as necessary, a method of placing the medical waste liquid in an appropriate container containing the medical waste liquid treating agent of the present invention in advance, A method in which the waste liquid is charged and mixed as necessary is exemplified. Further, the medical waste liquid treating agent of the present invention may be used alone, or may be used by wrapping it in a water-soluble film, paper, or a film of a nonionic water-absorbing resin used in the present invention.

[0029]

EXAMPLES The present invention will be described in more detail with reference to Production Examples, Examples and Comparative Examples, but the present invention is not limited to these Examples. The water-absorbent resin obtained in the production examples and the medical waste liquid treating agents obtained in the examples and comparative examples were evaluated according to the following methods. 1. Test items and method for water-absorbent resin (1) Water-absorbing capacity [g (0.9% by weight saline) / g (resin)] Water-absorbent resin 1 weighed in 200 mL of 0.9% by weight saline
After stirring for 24 hours, the mixture was filtered through a 200-mesh wire gauze, and the weight of the water-absorbing gel after filtration was taken as the water-absorbing ability. (2) Median particle size 50 g of the water-absorbent resin is weighed, sieved using a JIS standard sieve, and weighed for each sieve. Based on the result, the median particle size at which the integrated weight becomes 50% Was calculated by the following equation.

[0030]

(Equation 1)

In the formula, A is the integrated value (g) when the weight is sequentially integrated from the coarser particle size distribution and the integrated value at a point where the integrated weight is less than 50% and the closest to 50% is obtained. And B is the sieve opening (μm) when the integrated value is obtained. D is a value obtained by sequentially integrating the weights in descending order of the particle size distribution.
The integrated value (g) when the integrated value of the point closest to% is obtained
And C is the sieve opening (μm) when the integrated value is obtained.

2. Test Items for Medical Waste Liquid Treatment Agent and Method (1) Solidification Time Artificial blood (sodium chloride 1) was placed in a 300 mL beaker.
Wt%, sodium carbonate 0.4 wt%, glycerin 10
200 mL of a sodium salt of carboxymethyl cellulose, 88.14% by weight of water), 5 g or 8 g of a weighed medical waste liquid treating agent was added, and the mixture was stirred to measure the time until the solution was solidified. . The same procedure was applied to bovine blood and a 20% ethanol aqueous solution. (2) Fluidity After measuring the solidification time, the beaker was tilted at 45 degrees and the state of the contents was visually observed. The evaluation is as follows. ○: Contents do not move ×: Contents move

Production Example 1 Production Method of Nonionic Water Absorbent Resin (Modified Polyalkylene Oxide) 100 parts by weight of sufficiently dehydrated polyethylene oxide having a number average molecular weight of 20,000 and ethylene oxide / propylene oxide having a number average molecular weight of 15,000 (copolymerization ratio: 8 / 2)
100 parts by weight of copolymer, 1,4-butanediol 3.1
5 parts by weight, 0.1 part by weight of dibutyltin dilaurate
In a storage tank A equipped with a stirrer kept at 0 ° C., a uniform mixture was obtained under a nitrogen gas atmosphere. Aside from this,
1,6-Hexamethylene diisocyanate was placed in storage tank B kept at 30 ° C. and stored under a nitrogen gas atmosphere. The mixture in storage tank A and the isocyanate in storage tank B were metered with metering pumps at 250 g / min and 9.64 g / min, respectively.
At a rate of 1 minute, the mixture is continuously supplied to a twin-screw extruder set at 170 to 200 ° C., mixed and reacted by the extruder, and a strand is discharged from the extruder outlet, and pelletized by a pelletizer. Was freeze-pulverized to obtain a polyalkylene oxide-modified product. The water-absorbing ability of the resulting modified polyalkylene oxide was 30 g / g, and the median particle diameter was 450 μm.

Production Example 2 Method for producing ionic water-absorbing resin (crosslinked polyacrylate) 1 L equipped with a stirrer, reflux condenser and nitrogen gas inlet tube
N-heptane 550m in a four-necked cylindrical round bottom flask
L was added. To this, 1.38 g of hexaglyceryl monobeherate (surfactant; NONION GV-106 manufactured by NOF Corporation) having an HLB of 13.1 was added and dispersed, and the temperature was raised to 50 ° C to remove the surfactant. 30 ℃ after dissolving
Cooled down. On the other hand, a 500 mL Erlenmeyer flask was separately prepared, and 92 g of an 80% by weight aqueous acrylic acid solution was added thereto.
Was added. 20.1% by weight while cooling from outside
152.6 g of an aqueous sodium hydroxide solution of
Mol% neutralization, and then potassium persulfate 0.11
g and 0.019 g of ethylene glycol diglycidyl ether as a cross-linking agent were further added and dissolved. Thereby, an aqueous solution of partially neutralized acrylic acid was obtained. next,
The whole amount of the aqueous solution of partially neutralized acrylic acid was added to the four-necked cylindrical round-bottomed flask and dispersed therein. After the inside of the system was replaced with nitrogen, the temperature was raised, and the bath temperature was maintained at 70 ° C. for 3 hours. To carry out a polymerization reaction. After completion of the polymerization reaction, the obtained slurry containing the crosslinked polyacrylate was dried at 120 ° C. for 2 hours to obtain 191.2 g of a crosslinked polyacrylate. The crosslinked product of polyacrylate obtained had a water absorption of 69 g / g and a median particle size of 270 μm.

Example 1 Modified product of polyalkylene oxide 15 obtained in Production Example 1
g and 85 g of the crosslinked polyacrylate obtained in Production Example 2
Was mixed with a Nauta mixer to obtain a water-absorbing material. The obtained water-absorbing material was used as a medical waste liquid treating agent as it was. The obtained medical waste liquid treating agent was evaluated for (1) solidification time and (2) fluidity performance. The results are shown in Tables 1 and 2.

Example 2 Modified polyalkylene oxide 40 obtained in Production Example 1
g and the crosslinked polyacrylate 60 obtained in Production Example 2
g and 10 g of bentonite were mixed with a Nauta mixer to obtain a medical waste liquid treating agent. The performance evaluation of (1) and (2) was performed on the obtained medical waste liquid treating agent.
The results are shown in Tables 1 and 2.

Example 3 7 g of the modified polyalkylene oxide obtained in Production Example 1
And 93 g of the crosslinked polyacrylate obtained in Production Example 2 were mixed with a Nauter mixer to obtain a water-absorbing material. The obtained water-absorbing material was used as a medical waste liquid treating agent as it was. The performance evaluation of (1) and (2) was performed on the obtained medical waste liquid treating agent. The results are shown in Tables 1 and 2.

Example 4 Modified polyalkylene oxide 50 obtained in Production Example 1
g and 50 g of the crosslinked polyacrylate obtained in Production Example 2
Was mixed with a Nauta mixer to obtain a water-absorbing material. The obtained water-absorbing material was used as a medical waste liquid treating agent as it was. The performance evaluation of (1) and (2) was performed on the obtained medical waste liquid treating agent. The results are shown in Tables 1 and 2.

Comparative Example 1 3 g of the modified polyalkylene oxide obtained in Production Example 1
And 97 g of the crosslinked polyacrylate obtained in Production Example 2 were mixed with a Nauter mixer to obtain a water-absorbing material. The obtained water-absorbing material was used as a medical waste liquid treating agent as it was. The performance evaluation of (1) and (2) was performed on the obtained medical waste liquid treating agent. The results are shown in Tables 1 and 2.

Comparative Example 2 Modified polyalkylene oxide 70 obtained in Production Example 2
g and 30 g of the crosslinked polyacrylate obtained in Production Example 2
Was mixed with a Nauta mixer to obtain a water-absorbing material. The obtained water-absorbing material was used as a medical waste liquid treating agent as it was. The performance evaluation of (1) and (2) was performed on the obtained medical waste liquid treating agent. The results are shown in Tables 1 and 2.

[0041]

[Table 1] (When 5 g of medical waste liquid treatment agent is added)

[0042]

[Table 2] (When 8 g of medical waste liquid treatment agent is added)

From Tables 1 and 2, it can be seen that the treatment solution for medical waste liquid of the present invention has a small decrease in water absorption capacity due to the electrolyte concentration in the waste liquid, and can solidify the waste liquid in a small amount.

[0044]

According to the present invention, 5 to 60% by weight of a nonionic water absorbent resin and 95 to 40% by weight of an ionic water absorbent resin
By using a medical waste liquid treating agent containing a water-absorbing material consisting of, it is possible to provide a medical waste liquid treating agent capable of solidifying the medical waste liquid in a small amount with a small decrease in water absorption ability due to the electrolyte concentration in the medical waste liquid. .

──────────────────────────────────────────────────続 き Continued on the front page (51) Int.Cl. ⁷ Identification symbol FI Theme coat ゛ (Reference) // A61G 12/00 A61G 12/00 W (72) Inventor Shuichi Karashima 1 Irifune-cho, Shimarima-ku, Himeji-shi, Hyogo Address Sumitomo Seika Co., Ltd. Functional Resin Research Laboratory (72) Inventor Kenya Matsuda 1 Irifune-cho, Himeji-shi, Hyogo Prefecture Sumitomo Seika Co., Ltd. Functional Resin Research Laboratory F-term (reference) AC13B AC17A AC17B AC21A AC21B AC35A AC35B AE05A AE05B AE06A AE06B DA08 DA11 EA20 FA01 FA07 FA21 4J002 CH02W CH05W CK02X GB01 GD03

Claims (3)

[Claims] 1. A medical waste liquid treating agent comprising a water-absorbing material comprising 5 to 60% by weight of a nonionic water-absorbing resin and 95 to 40% by weight of an ionic water-absorbing resin. 2. The medical waste liquid treating agent according to claim 1, wherein the nonionic water-absorbing resin is a modified polyalkylene oxide obtained by reacting a polyalkylene oxide and a polyol with an isocyanate compound. 3. The ionic water-absorbing resin is at least one selected from the group consisting of a crosslinked product of a polyacrylate, a crosslinked product of a starch-acrylate graft copolymer, and a crosslinked product of an isobutylene-maleic anhydride copolymer. The medical waste liquid treating agent according to claim 1, which is a seed.