JP2002065879A - Mask - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a mask capable of positively catching the microorganism and showing the excellent pasteurization effect to the caught microorganism. SOLUTION: This mask 10 for covering a mouth 16 and a nose 18 is provided with a filter 24 carrying a biguanide-based antibacterial agent.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a mask, and more particularly to the selection of an antibacterial agent suitable for preventing infection by pathogenic microorganisms that cause droplet infection or air infection, and improvement of the internal structure thereof.

[0002]

2. Description of the Related Art Conventionally, a mask covering the nose and mouth has been used in order to trap fine particles floating in the air and to prevent scattering of microorganisms contained in sneezing and coughing. By the way, recently, many anti-bacterial functions have been considered in life related products such as stationery, tableware, and home appliances.
As for the mask, various antibacterial masks carrying an antibacterial agent have been developed (for example, JP-A-11-200245).
And JP-A-10-33701.

In the antibacterial mask, a plant extract is generally used as an antibacterial agent in consideration of safety to the human body and to avoid rash on the skin. According to the antibacterial mask, the growth of attached bacteria can be suppressed, and the mask can be kept clean.

[0004]

In the medical field, barber / beauty field, food service center, cafeteria, restaurant, food preparation and processing field, school, hotel, etc., where hygiene management is more important recently, for example, There are the following uses. (1) Prevention of infection by pathogenic microorganisms floating in the air (for example, influenza virus, tuberculosis bacterium, MRSA, etc.). (2) Hosts susceptible to infection by pathogenic microorganisms resident in the oral and nasal cavities of healthy subjects (leukemia patients, organ transplant patients, cancer patients, etc.)
Infection prevention. (3) Prevent infection from infectious disease patients to healthcare professionals, barbers and beauty workers. (4) Hygiene management of food cooking and processing workers.

[0005] However, even in the case of the antibacterial mask using the plant extract, in order to use it in the above-mentioned applications (1) to (4), active use of pathogenic microorganisms that cause droplet infection and air infection is aggressive. There is room for improvement in the trapping effect and the excellent antibacterial effect against the trapped microorganisms. The present invention has been made in view of the above-described problems of the related art, and an object of the present invention is to provide a mask that can actively capture microorganisms and exert an excellent antibacterial effect on the captured microorganisms. .

[0006]

The present inventors have conducted intensive studies on antibacterial agents suitable for use in masks in the above-mentioned applications (1) to (4). Positive trapping effect on pathogenic microorganisms that cause, excellent antibacterial effect on trapped microorganisms, broad spectrum antibacterial spectrum, excellent persistence of the antibacterial effect, very little effect on human body In terms of points,
It has been found that a biguanite antibacterial agent, particularly polyhexamethylene biguanite (PHMB), is preferable.

Further, the present inventors have studied the amount of the biguanite antibacterial agent to be carried.
In the range of 0 ppm or more and 5000 ppm or less, the filter is impregnated with an aqueous solution of a biguanite-based antibacterial agent prepared to a predetermined concentration, and dried, so that the filter carries the biguanite-based antibacterial agent. The present inventors have found that the present invention is suitable for use as a mask, and have completed the present invention. In order to achieve the above object, a mask according to the present invention is characterized in that a mask covering a mouth and a nose is provided with a filter carrying a biguanite antibacterial agent.

[0008] In the present invention, the filter is impregnated with an aqueous solution of a biguanite antibacterial agent adjusted to a predetermined concentration within a range of 150 ppm or more and 5000 ppm or less, and dried, whereby the biguanite-based filter is added to the filter. It is preferable to carry an antibacterial agent. That is,
When the concentration of the aqueous solution of the biguanite-based antibacterial agent is lower than 150 ppm, the effect of trapping pathogenic microorganisms causing droplet infection or airborne infection, and the effect of trapping microorganisms may not be sufficiently exhibited.

On the other hand, when the concentration is higher than 5000 ppm, the effect of capturing with a mask and the antibacterial effect are sufficient, but the production cost and the like are increased, the antibacterial agent is liable to fall off, and skin irritation is caused. In some cases, negative aspects such as an effect on the human body appear. In the present invention, the loading amount of the biguanite antibacterial agent is 0.1 g of the antibacterial agent per 1 cm ^{3 of the} filter at the time of use.
As mentioned above, it is preferable that it is 1.0 g or less.

[0010] In the present invention, it is also preferable to provide a base for sandwiching the filter from both sides thereof. Also,
In the present invention, when it is mainly desired to prevent the scattering of microorganisms to the outside, it is preferable to provide a fine particle capturing portion on the face side between the antibacterial agent-carrying filter and the base. Also,
In the present invention, when it is mainly desired to prevent the invasion of microorganisms from the outside, it is preferable to provide a fine particle capturing portion on the outside between the antibacterial agent-carrying filter and the base.

Further, in the present invention, when it is desired to prevent the scattering of microorganisms to the outside and the invasion of microorganisms from the outside,
It is preferable to provide a particle capturing unit on the face side and the external side between the antibacterial agent-carrying filter and the base, respectively. Here, the fine particle capturing unit is capable of capturing fine particles other than microorganisms to be antibacterial.

The filter carrying a biguanite-based antibacterial agent herein includes a filter having the above-mentioned antibacterial agent-carrying filter sandwiched between bases, a filter having an antibacterial agent directly carried on the base, and the like. . Examples of the filter used in the present invention include nylon, polyester, paper, gauze cloth, and the like having a fineness enough to prevent bacteria from passing therethrough.

The types of microorganisms against which the biguanite antibacterial agent used in the present invention exerts an antibacterial effect include various types. For example, Escherichia coli, enterohemorrhagic Escherichia coli, Staphylococcus aureus, Drug-resistant Staphylococcus aureus, Pseudomonas aeruginosa, Candida fungi and the like are mentioned as examples. Examples of the fine particle capturing unit used in the present invention include, for example, a filter made of paper, cloth, or the like, which is very fine compared to the base.

[0014]

Preferred embodiments of the present invention will be described below with reference to the drawings. FIG. 1 shows an example of mounting a mask according to an embodiment of the present invention on a human, and FIG. 2 shows an exploded perspective view of the mask according to the present embodiment.
The mask 10 shown in the figure is, for example, 95 mm long and 125 m wide.
A mask main body 12 having a size of m and an ear cord 14 are included. In a state where the mask body 12 covers the mouth 16 and the nose 18 of the human, the ear cord 14 is put on the ear 20.

In the present embodiment, the gauze 22a and the gauze 22a are arranged in order from the outside to the face side in a state of being mounted on a human.
2b (base), between the gauze 22a and 22b, a 0.5 mm thick antibacterial agent impregnated filter (antibacterial agent-carrying filter) 24 and a fine particle capturing material (very finer than the gauze 22a and 22b) A fine particle capturing section 26 is provided. By configuring the mask as described above,
The trapping of fine particles floating in the air, the prevention of scattering of microorganisms contained in sneezing and coughing of the user can be prevented, and the mask can be kept clean by the filter impregnated with the antibacterial agent.

The antibacterial agent carried on the filter impregnated with the antibacterial agent is usually a plant extract. However, it is necessary to positively capture pathogenic microorganisms which cause flying infection or air infection. In many cases, it is difficult to maintain the antibacterial effect against the microorganisms.

[0017]Selection of antibacterial agent  Therefore, the first characteristic of this embodiment is that
Antibacterial agent loaded on antibacterial agent impregnated filter 24 of mask 10
As compared to plant extracts such as essential oils,
Superior in capturing effect, antibacterial effect, antibacterial effect,
Compared to antibacterial agents such as quaternary ammonium salts, a broader antibacterial
Biguanite antibacterial agents having a spectrum, among them
Using polyhexamethylene biguanite (PHMB)
That is.

For this reason, in this embodiment, the PHM
B is diluted with sterile distilled water, the filter is impregnated with a 2000 ppm aqueous solution thereof, and the dried antibacterial agent impregnated filter 24 is placed between the gauze 22a and 22b of the mask 10.

<Capture effect of microorganism> The biguanite antibacterial agent used in the present invention is a biguanide group (-NHC (= NH) NHC).
(= NH) NH-), in which polyhexamethylene biguanite (PHMB) is a positively charged substance, and is extremely bound by ionic bonds with fine particles such as negatively charged microorganisms. It has a trapping effect of binding efficiently.

As a result, as shown in FIG. 3, the PHMB carried on the filter 24 impregnated with the antibacterial agent of the present embodiment.
Has a trapping effect of extremely efficiently binding to fine particles such as negatively charged microorganisms and pollen by ionic bonding. Further, PHMB carried on the antibacterial agent-impregnated filter 24 of the present embodiment not only captures pathogenic microorganisms,
It also has a sufficient effect on trapping negatively charged fine particles such as pollen and house dust that cause allergic rhinitis and bronchitis, etc., as compared to the case where plant extracts are used as antibacterial agents for masks. , Keeps pathogens captured by masks for a long time.

<Antibacterial Effect> The PHMB carried on the antibacterial agent-impregnated filter 24 of the present embodiment exerts an antibacterial effect by acting on the membrane of the captured pathogenic microorganisms. That is, PHMB exerts an antibacterial effect by causing damage to the cell membrane of microorganisms and causing leakage of potassium ions from the cytoplasm by the same antibacterial mechanism as quaternary ammonium salts.

Therefore, the filter 24 impregnated with the antibacterial agent of the present embodiment has a sufficient antibacterial effect against pathogenic microorganisms that cause trapped flying infection or air infection as compared with the filter using a plant extract as the antibacterial agent. Demonstrate.

<Persistence of Antibacterial Effect> PHMB supported on the antibacterial agent-impregnated filter 24 of the present embodiment is as follows:
Compared to the case where a plant extract such as an essential oil is used, the antibacterial effect is superior in persistence. Further, in this embodiment, since both surfaces of the filter 24 are sandwiched between the gauze 22a and 22b, the PHMB is securely held without falling off from the filter 24. Thereby, the effect of capturing the microorganisms and the antibacterial effect on the captured microorganisms are exhibited for a long time.

<Antibacterial Spectrum> PHMB carried on the antibacterial agent-impregnated filter 24 of this embodiment has a wider antibacterial spectrum than quaternary ammonium salts and the like. It exhibits antibacterial properties against Escherichia coli, Staphylococcus aureus, multidrug-resistant Staphylococcus aureus, Pseudomonas aeruginosa, Candida fungi and the like.

<Regarding Effect of Antimicrobial Agent on Human Body> PHM carried on the antimicrobial agent impregnated filter 24 of the present embodiment
B has a very high safety for cytotoxicity, mutagenicity, acute toxicity, etc. in addition to a high capturing effect on microorganisms and the like and an antibacterial effect on the captured microorganisms and the like. preferable.

<Study of Antibacterial Agent Carrying Amount> When the filter is immersed in an aqueous solution of a biguanite-based antibacterial agent to prepare an antibacterial agent-impregnated filter 24 as described above, if the concentration of the aqueous solution is lower than 150 ppm, In some cases, the effect of trapping pathogenic microorganisms causing droplet infection or air infection and the antibacterial effect of the trapped microorganisms are not sufficiently exhibited. On the other hand, when the concentration of the aqueous solution is 5000 pp
When it is higher than m, the masking effect and antibacterial effect with the mask are sufficient, but the manufacturing cost, etc. are increased, the antibacterial agent is easily dropped off, and the effects on the human body such as skin rash appear. May increase.

Therefore, the third characteristic feature of the present invention is that when the filter is immersed in an aqueous solution of a biguanite-based antibacterial agent to prepare the antibacterial agent-impregnated filter 24, the concentration of the aqueous solution is set to 150 ppm or more and 5000 ppm or less. It was done. Thus loading of the Biguanaito antibacterial agent, in use, the filter 1 cm ³ to antimicrobials more than 0.1 g, and not more than 1.0 g. For this reason, in this embodiment, a 2000 ppm PHMB aqueous solution is used. As a result, in the present embodiment, a positive capturing effect on pathogenic microorganisms and a sufficient antibacterial effect on captured microorganisms are obtained, and a biguanite-based antibacterial agent is used within an optimum range for the mask of the present embodiment.

The antibacterial agent impregnated filter 24 prepared by the simple method as described above is used for the mask of the present embodiment because the outer side surface of the antibacterial agent impregnated filter 24 has gauze 22a and the side surface of the face has fine particles. Material 26 and gauze 22
This is because the PHMB is securely held without falling off from the filter 24 because it is firmly sandwiched by b.

That is, for example, in a sanitary article such as a diaper in which the surface of the filter carrying the antibacterial agent is in direct contact with human skin, in order to carry the antibacterial agent on the filter firmly, It is necessary to perform steps such as pre-processing and post-processing, which is troublesome. On the other hand, in the mask of the present embodiment, since both surfaces of the antibacterial agent impregnated filter 24 are sandwiched between the gauze 22a and 22b as described above,
When carrying the antibacterial agent on the filter, the filter can be easily manufactured by the method described above without requiring the special treatment as described above. This simplifies the manufacturing process, reduces manufacturing cost, and the like, and enables mass production.

<Inner Structure 1 of Mask> Although the filter 24 impregnated with the antibacterial agent of this embodiment has an excellent capturing effect and an antibacterial effect on pathogenic microorganisms as described above, the mask is a target for capturing and antibacterial. In addition to microorganisms, various fine particles such as dust are captured. If such fine particles directly adhere to the antibacterial agent-impregnated filter 24 or adhere to the filter 24 together with the microorganism to be antibacterial, the capturing effect and the antibacterial effect of the filter 24 may decrease over time. .

Therefore, the fourth characteristic of the present invention is that the antibacterial agent of the present invention exerts the effect of capturing microorganisms and the antibacterial effect for a longer period of time, and is mainly used to prevent scattering to the outside. Is the filter 24 and the body 22
That is, the fine particle trapping material 26 is provided on the outer side between a and 22b. As a result, the exhalation from the mask user
After the relatively large-diameter particles and the like are captured by the face-side gauze 22b, and the fine particles 28 and the like other than the pathogenic microorganism to be subjected to the antibacterial that have passed through the face-side gauze 22b are captured by the fine particle capturing material 26, Agent impregnated filter 24
To reach.

Therefore, since extraneous substances such as the fine particles 28 other than the pathogenic microorganisms to be subjected to antibacterial treatment are removed from the breath from the mask user reaching the antibacterial agent impregnated filter 24, the filter is impregnated with the antibacterial agent impregnated filter. In 24, the pathogenic microorganisms 30 and the like to be antibacterial are efficiently captured, and an excellent antibacterial effect on the captured microorganisms 30 is exhibited for a long time.

As a result, the release of the pathogenic microorganisms 30 resident in the mouth and nasal cavity of the mask user to the outside is greatly reduced, and the captured pathogenic microorganisms 30 fall off from the mask and propagate on the mask. And the like can be greatly reduced. As described above, according to the mask according to the present embodiment, the antibacterial agent-impregnated filter 24 carrying an appropriate amount of PHMB as described above is incorporated in the main body 12.

As a result, the mask according to this embodiment is
Actively captures pathogenic microorganisms floating in the air and pathogenic microorganisms flying from the oral cavity and nasal cavity, and keeps the captured microorganisms firmly held. Then, sufficient antibacterial action against the captured microorganisms is performed for a long time.

[0035]Modified example  In addition, the mask of the present invention is limited to the above configuration.
However, various modifications are possible within the scope of the invention.
You. For example, in the above-mentioned configuration, mainly the scattering of microorganisms to the outside
The mask should be worn on humans in order to prevent
In order from the outside to the face side in the state, the outer gauze and the filter
And an example in which a fine particle capturing material and a face side gauze are provided.
However, depending on the purpose of use,
It is also preferable to employ a disk structure.

<Structure Example 2> When it is mainly desired to prevent the invasion of microorganisms from the outside, it is preferable to employ a mask structure as shown in FIG. Note that portions corresponding to those in FIG. 3 are denoted by reference numerals 100, and description thereof is omitted. That is, as shown in the figure, the mask body 112 is attached to a human and the outer gauze 122 is arranged in order from the outside to the face side.
a, fine particle capturing material 126, and antibacterial agent impregnated filter 1
24 and a face-side gauze 122b.

As a result, the air from the outside is trapped by the outer gauze 122a to trap fine particles and the like having a relatively large diameter, and the fine particles 132 and the like other than the pathogenic microorganism to be subjected to the antibacterial which have passed through the outer gauze 122a. Capture material 12
After being captured by 6, the antimicrobial agent impregnated filter 124 is reached. Therefore, extraneous substances such as the fine particles 132 other than the pathogenic microorganisms to be subjected to antibacterial treatment are removed from the external air that has reached the antibacterial agent impregnated filter 124. Thus, the pathogenic microorganism 134 or the like is efficiently captured, and an excellent antibacterial effect is exerted on the captured microorganism 134 for a long time.

Thus, the pathogenic microorganism 134 from the outside
Greatly reduces the intrusion of mask users.
That the captured pathogenic microorganisms 134 fall off the mask,
Propagation with the mask can be greatly reduced.

<Structural Example 3> Further, when it is desired to prevent the scattering of microorganisms to the outside and to prevent the invasion of microorganisms from the outside, it is preferable to employ a mask structure as shown in FIG. The parts corresponding to those in FIG.
4 is added to the portion corresponding to FIG.

That is, as shown in FIG.
Reference numeral 12 denotes an outer gauze 222a and an outer particulate capturing material 226 in order from the outer side to the face side while being worn on a human.
a, an antibacterial agent-impregnated filter 214, a face-side particulate capturing material 226b, and a face-side gauze 222b. As a result, in the exhalation from the mask user, relatively large-diameter fine particles and the like are captured by the face-side gauze 222b, and fine particles 228 other than the pathogenic microorganism to be subjected to antibacterial, which have passed through the face-side gauze 222b, are further removed. After being captured by the face-side fine particle capturing material 226b, it reaches the antibacterial agent impregnated filter 224.

Therefore, since extraneous substances such as the fine particles 228 other than the pathogenic microorganisms to be subjected to antibacterial treatment are removed from the breath from the mask user that has reached the antibacterial agent impregnated filter 224, the filter is impregnated with the antibacterial agent impregnated filter. In 224, pathogenic microorganisms 230 and the like to be antibacterial are efficiently captured,
An excellent antibacterial effect is exerted on the captured microorganisms 230 for a long time.

On the other hand, air from the outside is supplied to the outer gauze 22.
2a captures relatively large-diameter fine particles and the like, and further, the fine particles 232 and the like other than the pathogenic microorganism to be antibacterial that have passed through the outer gauze 222a are captured by the fine particle capturing material 226. To reach. Therefore, since extraneous substances such as the fine particles 232 other than the pathogenic microorganisms to be subjected to antibacterial treatment are removed from the external air that has reached the antibacterial agent impregnated filter 224, the antibacterial agent impregnated filter 224 performs the antibacterial treatment. Pathogens 234 and the like are efficiently captured, and an excellent antibacterial effect is exerted on the captured microorganisms 234 for a long time.

As a result, the release of the pathogenic microorganisms 230 resident in the mouth and the nasal cavity of the mask user to the outside and the invasion of the pathogenic microorganisms 234 from the outside into the mask user are greatly reduced. Captured pathogenic microorganisms 23
0, 234 can be greatly reduced from falling off from the mask, breeding on the mask, and the like.

<Method of Carrying Antibacterial Agent> In each of the above structures, an example was described in which a filter was immersed in an aqueous solution of an antibacterial agent having a specific concentration to prepare an antibacterial agent-carrying filter. However, the present invention is not limited to this, and an antibacterial agent may be carried on one or both surfaces of the filter by spraying or applying a specific concentration of an antibacterial agent aqueous solution according to the purpose of use.

Further, in each of the above-described structures, the example in which the antibacterial agent-impregnated filter is incorporated between the two gauze pieces has been described, but the mask of the present invention is not limited to this.
The antibacterial agent may be directly carried on the gauze without using an antibacterial agent-impregnated filter. Furthermore, the antibacterial agent-carrying filter used for the mask of the present invention is usually used in a dry state, but may be used in a semi-dry state, for example, instead of a completely dry state depending on the purpose of use.

[0046]

【Example】Antibacterial test  Next, within the concentration range used in the mask of the present invention,
PHMB aqueous solution, antibacterial test of the PHMB impregnated filter
Was done.

<Test Bacteria> E. coli (Escherichia coil) Enterohemorrhagic E. coil O15
7: H7) Staphlococcus aureus Multi-drug resistant Staphylococcus aureus (MRSA) Pseudomonas aeruginosa Candida albicans

<Preparation of PHMB Aqueous Solution> PHMB is diluted with sterilized distilled water to prepare aqueous solutions having various concentrations shown in Table 1 within a range of 150 ppm to 5000 ppm.

<Preparation of PHMB impregnated filter> 2000
The filter is impregnated with an aqueous solution of PHMB in ppm. The filter impregnated with the PHMB aqueous solution is dried. The PHMB aqueous solution thus prepared and the PHMB-impregnated filter were subjected to an antibacterial test by the following method.

<Test Method> (1) The pre-cultured bacteria were washed with physiological saline to about 1 × 10 ⁶ (ce)
lls / ml) and smear the surface of the agar medium with a sterile cotton swab. (2) [PHMB aqueous solution] 20 µl of the diluted PHMB aqueous solution is dropped on the surface of the agar medium of (1).

[PHMB Impregnated Filter] The PHMB impregnated filter was formed on a disk having a diameter of 5 mm.
Place the impregnated filter disk on the same agar medium surface. (3) Incubate at 37 ° C. for 18 to 24 hours, and observe the growth inhibition by a PHMB aqueous solution and a PHMB-impregnated filter disk.

<Test Results> The test was performed three times and the results were summarized. Table 1 shows the antibacterial activity of PHMB.
Table 2 shows the antibacterial action of the filter disk impregnated with B. PHMB aqueous solution of each concentration was dropped, and PHM
At the site where the B-impregnated filter disk was placed, the size (mm) of the portion where no bacteria had grown was measured.

Further, in the PHMB aqueous solution and in the figure,
FIG. 6 shows a photograph showing the antibacterial effect of the following PHMB-impregnated filter disk (diameter 5 mm, thickness 0.5 mm) as a sample on Escherichia coli, and FIG. 7 shows the antibacterial effect on enterohemorrhagic Escherichia coli. FIG. 8 shows a photograph showing the antibacterial effect on cocci, FIG. 9 shows a photograph showing the antibacterial effect on multidrug-resistant Staphylococcus aureus, and FIG. 10 shows a photograph showing the antibacterial effect on Pseudomonas aeruginosa.
And a photograph showing the antibacterial effect against Candida was shown in FIG. In the figure, the portion where the bacteria are growing is shown in white on the surface of the agar medium, and the portion where the antibacterial effect is exerted is shown in black.

[0054]

[Table 1] PHMB concentration (ppm) 150.0 312.5 625 1250 2500 5000 E. coil 6.8 ± 1.1 7.3 ± 2.1 7.5 ± 1.4 7.8 ± 2.2 8.1 ± 1.2 9.8 ± 1.3 O157: H7 6.6 ± 1.3 7.2 ± 1.6 7.4 ± 1.1 7.3 ± 1.7 7.2 ± 2.1 7.5 ± 1.1 S. aureus 6.8 ± 1.3 7.1 ± 0.2 7.2 ± 1.1 7.4 ± 1.7 8.3 ± 1.4 8.6 ± 2.1 MRSA 6.6 ± 1.5 7.2 ± 1.2 7.2 ± 1.3 7.3 ± 1.6 7.6 ± 1.4 7.5 ± 1.2 P. aeruginosa 6.6 ± 1.2 7.0 ± 1.3 7.0 ± 1.6 7.2 ± 1.2 7.5 ± 1.1 7.6 ± 1.1 C. albicans 2.6 ± 1.4 3.6 ± 1.6 6.7 ± 1.1 6.7 ± 1.3 6.9 ± 1.2 7.3 ± 1.1

[0055]

[Table 2] PHMB-impregnated filter disk (diameter 5 mm, thickness 0.5 mm) E. coil 7.2 ± 1.3 O157: H7 7.0 ± 1.1 S. aureus 8.1 ± 2.0 MRSA 6.9 ± 2.2 P. aeruginosa 6.8 ± 1.3 C. albicans 6.6 ± 1.5

As is clear from Tables 1 and 2, and FIGS. 6 to 11, the PHMB aqueous solution diluted to each of the above concentrations of 150 to 5000 ppm and the filter disk impregnated with 2000 ppm of PHMB showed no inhibition of the growth against the above bacteria. Was done. Therefore, the PHMB aqueous solution whose concentration is adjusted as described above is directly supported on the base according to the present embodiment, and the PHMB-impregnated filter is provided between the bases according to the present embodiment to prevent various types of captured microorganisms. It is thought that it exerts an excellent antibacterial effect on it.

[0057]

As described above, according to the mask of the present invention, since a filter carrying a biguanite-based antibacterial agent, in particular, a polyhexamethylenebiguanite-supported antibacterial agent is provided, microorganisms can be positively treated. And exhibit an excellent antibacterial effect on the captured microorganisms. Further, in the present invention, the filter is impregnated with an aqueous solution of a biguanite antibacterial agent prepared to a predetermined concentration within a range of 150 ppm or more and 5000 ppm or less and dried, and the amount of the antibacterial agent loaded is determined when the filter is used. When the amount of the antibacterial agent is 0.1 g or more and 1.0 g or less per 1 cm ³ , the biguanite antibacterial agent can be suitably used for a mask. Furthermore, in the present invention, it is provided with a base sandwiching both surfaces of the antibacterial agent-carrying filter, and, depending on the purpose of use, between the antibacterial agent-carrying filter and the base, it is possible to capture fine particles other than microorganisms to be antibacterial. By providing the fine particle capturing portion, the capturing effect and the antibacterial effect of the biguanite antibacterial agent can be obtained for a longer time.

[Brief description of the drawings]

FIG. 1 is an explanatory diagram of a mounting example of a mask according to a first embodiment of the present invention.

FIG. 2 is an exploded perspective view of the mask shown in FIG.

FIG. 3 is an explanatory diagram of an operation of the mask shown in FIG. 1;

FIG. 4 is an explanatory diagram of a mask according to a second embodiment of the present invention.

FIG. 5 is an explanatory diagram of a mask according to a third embodiment of the present invention.

FIG. 6 is a photograph showing the antibacterial effect of the antibacterial agent used for the mask of the present invention on Escherichia coli.

FIG. 7 is a photograph showing the antibacterial effect of the antibacterial agent used for the mask of the present invention on enterohemorrhagic Escherichia coli.

FIG. 8 is a photograph showing the antibacterial effect of the antibacterial agent used for the mask of the present invention on Staphylococcus aureus.

FIG. 9 is a photograph showing the antibacterial effect of the antibacterial agent used for the mask of the present invention on multidrug-resistant Staphylococcus aureus.

FIG. 10 is a photograph showing the antibacterial effect of the antibacterial agent used for the mask of the present invention on Pseudomonas aeruginosa.

FIG. 11 is a photograph showing the antibacterial effect of the antibacterial agent used for the mask of the present invention on Candida.

[Explanation of symbols]

10 Mask 12, 112, 212 Body 22, 122, 222 Gauze (base) 24, 124, 224 Antibacterial agent impregnated filter (antibacterial agent carrying filter) 26, 126, 226 Fine particle capturing material (fine particle capturing section)

Claims (8)

[Claims] 1. A mask for covering a mouth and a nose, comprising a filter carrying a biguanite antibacterial agent. 2. The mask according to claim 1, wherein the biguanite antibacterial agent is polyhexamethylene biguanite. 3. The mask according to claim 1, wherein the filter is impregnated with an aqueous solution of a biguanite antibacterial agent adjusted to a predetermined concentration within a range of 150 ppm to 5000 ppm, and dried. A mask, wherein the filter carries the biguanite antibacterial agent. 4. The mask according to claim 1, wherein the amount of the biguanite-based antibacterial agent is 0.1 g or more per 1 cm ^{3 of the} filter when used.
A mask weighing 0 g or less. 5. The mask according to claim 1, further comprising a base for sandwiching the antibacterial agent-carrying filter from both sides thereof. 6. The mask according to claim 5, wherein when it is desired to mainly prevent the scattering of microorganisms to the outside, fine particles other than microorganisms to be subjected to antibacterial treatment are provided on the face side between the antibacterial agent-carrying filter and the base. 1. A mask comprising a fine particle capturing portion capable of capturing a particle. 7. The mask according to claim 5, wherein when it is mainly desired to prevent invasion of microorganisms from the outside, fine particles other than microorganisms to be antibacterial are provided on the outer side between the antibacterial agent-carrying filter and the base. 1. A mask comprising a fine particle capturing portion capable of capturing a particle. 8. The mask according to claim 5, wherein, when it is desired to prevent scattering of microorganisms to the outside and invasion of microorganisms from the outside, a face side and an outside side between the antibacterial agent-carrying filter and the base portion are provided. Masks each provided with a fine particle capturing portion capable of capturing fine particles other than microorganisms to be antibacterial.