JP2001515508A5 - - Google Patents

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Publication number
JP2001515508A5
JP2001515508A5 JP1998540629A JP54062998A JP2001515508A5 JP 2001515508 A5 JP2001515508 A5 JP 2001515508A5 JP 1998540629 A JP1998540629 A JP 1998540629A JP 54062998 A JP54062998 A JP 54062998A JP 2001515508 A5 JP2001515508 A5 JP 2001515508A5
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JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP1998540629A
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English (en)
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JP2001515508A (ja
JP4467648B2 (ja
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Priority claimed from PCT/US1998/004873 external-priority patent/WO1998041092A1/en
Publication of JP2001515508A publication Critical patent/JP2001515508A/ja
Publication of JP2001515508A5 publication Critical patent/JP2001515508A5/ja
Application granted granted Critical
Publication of JP4467648B2 publication Critical patent/JP4467648B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Description

Figure 2001515508
Figure 2001515508
Figure 2001515508
JP54062998A 1997-03-14 1998-03-13 新規インドールカルボキサミド、医薬組成物およびカルパインの阻害方法 Expired - Lifetime JP4467648B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4058997P 1997-03-14 1997-03-14
US60/040,589 1997-03-14
PCT/US1998/004873 WO1998041092A1 (en) 1997-03-14 1998-03-13 Novel indolecarboxamides, pharmaceutical compositions and methodsof inhibiting calpain

Publications (3)

Publication Number Publication Date
JP2001515508A JP2001515508A (ja) 2001-09-18
JP2001515508A5 true JP2001515508A5 (ja) 2005-11-10
JP4467648B2 JP4467648B2 (ja) 2010-05-26

Family

ID=21911807

Family Applications (1)

Application Number Title Priority Date Filing Date
JP54062998A Expired - Lifetime JP4467648B2 (ja) 1997-03-14 1998-03-13 新規インドールカルボキサミド、医薬組成物およびカルパインの阻害方法

Country Status (7)

Country Link
US (1) US6214856B1 (ja)
EP (1) EP1018878B1 (ja)
JP (1) JP4467648B2 (ja)
CA (1) CA2284041C (ja)
DE (1) DE69826881T2 (ja)
ES (1) ES2230676T3 (ja)
WO (1) WO1998041092A1 (ja)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19817459A1 (de) 1998-04-20 1999-10-21 Basf Ag Neue heterozyklische substituierte Amide, Herstellung und Anwendung
WO2000021550A2 (en) * 1998-10-13 2000-04-20 President And Fellows Of Harvard College Methods and compositions for treating neurodegenerative diseases
FR2890071B1 (fr) 2005-08-30 2007-11-09 Fournier Sa Sa Lab Nouveaux composes de l'indole
BR112014021498A2 (pt) * 2012-02-29 2017-07-18 Institute For Hepatitis And Virus Res composto, composição e método para tratar uma doença associada com formação de dna circular covalentemente fechado
WO2017156071A1 (en) 2016-03-09 2017-09-14 Blade Therapeutics, Inc. Cyclic keto-amide compounds as calpain modulators and methods of production and use thereof
US11292801B2 (en) 2016-07-05 2022-04-05 Blade Therapeutics, Inc. Calpain modulators and therapeutic uses thereof
AU2017336523B2 (en) 2016-09-28 2022-07-21 Blade Therapeutics, Inc. Calpain modulators and therapeutic uses thereof
CA3067063A1 (en) * 2017-06-23 2018-12-27 Blade Therapeutics, Inc. Calpain modulators and therapeutic uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0539503T3 (da) 1990-07-16 1996-05-13 Merrell Pharma Inc Excitatoriske aminosyreantagonister
CA2071621C (en) * 1991-06-19 1996-08-06 Ahihiko Hosoda Aldehyde derivatives
US5190968A (en) * 1991-09-30 1993-03-02 Merck Frosst Canada, Inc. (Polycyclic-arylmethoxy) indoles as inhibitors of leukotriene biosynthesis

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