JP2001513111A5 - - Google Patents

Download PDF

Info

Publication number
JP2001513111A5
JP2001513111A5 JP1998538595A JP53859598A JP2001513111A5 JP 2001513111 A5 JP2001513111 A5 JP 2001513111A5 JP 1998538595 A JP1998538595 A JP 1998538595A JP 53859598 A JP53859598 A JP 53859598A JP 2001513111 A5 JP2001513111 A5 JP 2001513111A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
JP1998538595A
Other languages
English (en)
Japanese (ja)
Other versions
JP2001513111A (ja
Filing date
Publication date
Priority claimed from US08/807,992 external-priority patent/US6022541A/en
Application filed filed Critical
Publication of JP2001513111A publication Critical patent/JP2001513111A/ja
Publication of JP2001513111A5 publication Critical patent/JP2001513111A5/ja
Ceased legal-status Critical Current

Links

JP53859598A 1997-03-03 1998-02-26 腫瘍付随血管(tumor−associated blood vessels)上の血管透過因子の複数のエピトープに結合する同時インビボイムノコンジュゲート Ceased JP2001513111A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/807,992 US6022541A (en) 1991-10-18 1997-03-03 Immunological preparation for concurrent specific binding to spatially exposed regions of vascular permeability factor bound in-vivo to a tumor associated blood vessel
US08/807,992 1997-03-03
PCT/US1998/003765 WO1998039037A1 (en) 1997-03-03 1998-02-26 Concurrent in-vivo immunoconjugate binding to multiple epitopes of vascular permeability factor on tumor-associated blood vessels

Publications (2)

Publication Number Publication Date
JP2001513111A JP2001513111A (ja) 2001-08-28
JP2001513111A5 true JP2001513111A5 (https=) 2005-10-06

Family

ID=25197602

Family Applications (1)

Application Number Title Priority Date Filing Date
JP53859598A Ceased JP2001513111A (ja) 1997-03-03 1998-02-26 腫瘍付随血管(tumor−associated blood vessels)上の血管透過因子の複数のエピトープに結合する同時インビボイムノコンジュゲート

Country Status (6)

Country Link
US (1) US6022541A (https=)
EP (1) EP0968002A4 (https=)
JP (1) JP2001513111A (https=)
AU (1) AU722722B2 (https=)
CA (1) CA2283295C (https=)
WO (1) WO1998039037A1 (https=)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6749853B1 (en) * 1992-03-05 2004-06-15 Board Of Regents, The University Of Texas System Combined methods and compositions for coagulation and tumor treatment
US5965132A (en) * 1992-03-05 1999-10-12 Board Of Regents, The University Of Texas System Methods and compositions for targeting the vasculature of solid tumors
US6824986B1 (en) * 1997-10-06 2004-11-30 University Of Cincinnati Methods for measuring in vivo cytokine production
IL128852A0 (en) * 1999-03-05 2000-01-31 Compugen Ltd Novel nucleic acid and amino acid sequences
US6783954B2 (en) * 1999-03-05 2004-08-31 Compugen Ltd. VEGF nucleic acid and amino acid sequences
EP1179541B1 (en) 1999-04-28 2004-06-16 Board Of Regents, The University Of Texas System Compositions and methods for cancer treatment by selectively inhibiting VEGF
US6703020B1 (en) 1999-04-28 2004-03-09 Board Of Regents, The University Of Texas System Antibody conjugate methods for selectively inhibiting VEGF
JP4343473B2 (ja) * 1999-06-21 2009-10-14 日本メジフィジックス株式会社 血漿蛋白質に結合親和性を有する薬剤の投与方法並びに当該投与方法に用いられる製剤
AU775373B2 (en) 1999-10-01 2004-07-29 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
FR2799465B1 (fr) * 1999-10-12 2004-02-13 Centre Nat Rech Scient Peptides ayant une activite de stimulation de la reponse immunitaire et de regeneration tissulaire
US6974791B2 (en) * 2000-03-16 2005-12-13 The University Of Pittsburgh Endothelial specific targeting
US7097840B2 (en) 2000-03-16 2006-08-29 Genentech, Inc. Methods of treatment using anti-ErbB antibody-maytansinoid conjugates
WO2003028840A2 (en) * 2001-09-27 2003-04-10 Board Of Regents, The University Of Texas System Combined compositions and methods for tumor vasculature coagulation and treatment
AU2002362646A1 (en) * 2001-10-09 2003-04-22 The Johns Hopkins University A phosphatase associated with metastasis
US8088387B2 (en) 2003-10-10 2012-01-03 Immunogen Inc. Method of targeting specific cell populations using cell-binding agent maytansinoid conjugates linked via a non-cleavable linker, said conjugates, and methods of making said conjugates
US8080253B2 (en) * 2004-02-05 2011-12-20 The Ohio State University Research Foundation Chimeric VEGF peptides
CN101970486A (zh) * 2007-10-25 2011-02-09 布里斯托尔大学 特异于血管内皮生长因子(vegf)的促血管发生同工型的抗体
NZ602675A (en) 2008-03-18 2014-03-28 Genentech Inc Combinations of an anti-her2 antibody-drug conjugate and chemotherapeutic agents, and methods of use

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4514505A (en) * 1982-05-21 1985-04-30 The Trustees Of Columbia University In The City Of New York Monoclonal antibody mixtures and use thereof for enhanced sensitivity immunoassays
WO1993008210A1 (en) * 1991-10-18 1993-04-29 Beth Israel Hospital Association Vascular permeability factor targeted compounds
US5776427A (en) * 1992-03-05 1998-07-07 Board Of Regents, The University Of Texas System Methods for targeting the vasculature of solid tumors
AU702250B2 (en) * 1994-07-11 1999-02-18 Board Of Regents, The University Of Texas System Methods and compositions for the specific coagulation of vasculature

Similar Documents

Publication Publication Date Title
JP2000509635A5 (https=)
JP2000510751A5 (https=)
JP2000509942A5 (https=)
JP2000507042A5 (https=)
JP2000509637A5 (https=)
JP2000509912A5 (https=)
JP2002514228A5 (https=)
JP2002512549A5 (https=)
JP2002544759A5 (https=)
JP2000509587A5 (https=)
JP2000507369A5 (https=)
JP2000508866A5 (https=)
JP2000508022A5 (https=)
JP2000508841A5 (https=)
JP2000508680A5 (https=)
JP2000509804A5 (https=)
JP2000509853A5 (https=)
JP2000509755A5 (https=)
JP2000510969A5 (https=)
JP2000510247A5 (https=)
JP2000508836A5 (https=)
JP2000509818A5 (https=)
JP2000509520A5 (https=)
JP2001513111A5 (https=)
JP2000508880A5 (https=)