JP2001508036A - ７員ラクタム環を含むペプチド類似体 - Google Patents

７員ラクタム環を含むペプチド類似体

Info

Publication number
JP2001508036A
JP2001508036A JP51907398A JP51907398A JP2001508036A JP 2001508036 A JP2001508036 A JP 2001508036A JP 51907398 A JP51907398 A JP 51907398A JP 51907398 A JP51907398 A JP 51907398A JP 2001508036 A JP2001508036 A JP 2001508036A
Authority
JP
Japan
Prior art keywords
ala
formula
gly
peptide
pharmaceutically acceptable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP51907398A
Other languages
English (en)
Japanese (ja)
Other versions
JP2001508036A5 (US06207644-20010327-C00004.png
Inventor
ルーク，リチャード・ウィリアム・アーサー
コットン，ロナルド
Original Assignee
ゼネカ・リミテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ゼネカ・リミテッド filed Critical ゼネカ・リミテッド
Publication of JP2001508036A publication Critical patent/JP2001508036A/ja
Publication of JP2001508036A5 publication Critical patent/JP2001508036A5/ja
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00—Drug, bio-affecting and body treating compositions
    • Y10S424/81—Drug, bio-affecting and body treating compositions involving autoimmunity, allergy, immediate hypersensitivity, delayed hypersensitivity, immunosuppression, immunotolerance, or anergy
JP51907398A 1996-10-19 1997-10-14 ７員ラクタム環を含むペプチド類似体 Withdrawn JP2001508036A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9621836.7A GB9621836D0 (en) 1996-10-19 1996-10-19 Peptide compounds
GB9621836.7 1996-10-19
PCT/GB1997/002837 WO1998017680A1 (en) 1996-10-19 1997-10-14 Peptide analogues containing a 7-membered lactam ring

Publications (2)

Publication Number Publication Date
JP2001508036A true JP2001508036A (ja) 2001-06-19
JP2001508036A5 JP2001508036A5 (US06207644-20010327-C00004.png) 2005-06-16

Family

ID=10801703

Family Applications (1)

Application Number Title Priority Date Filing Date
JP51907398A Withdrawn JP2001508036A (ja) 1996-10-19 1997-10-14 ７員ラクタム環を含むペプチド類似体

Country Status (10)

Country Link
US (1) US6207644B1 (US06207644-20010327-C00004.png)
EP (1) EP0932618B1 (US06207644-20010327-C00004.png)
JP (1) JP2001508036A (US06207644-20010327-C00004.png)
AT (1) ATE256145T1 (US06207644-20010327-C00004.png)
AU (1) AU4633097A (US06207644-20010327-C00004.png)
DE (1) DE69726743T2 (US06207644-20010327-C00004.png)
GB (1) GB9621836D0 (US06207644-20010327-C00004.png)
TW (1) TW492868B (US06207644-20010327-C00004.png)
WO (1) WO1998017680A1 (US06207644-20010327-C00004.png)
ZA (1) ZA979338B (US06207644-20010327-C00004.png)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997046578A1 (en) 1996-06-07 1997-12-11 Zeneca Limited Peptide derivatives
EP1198271A4 (en) 1999-06-25 2009-01-21 Univ Emory DEVICES AND METHODS FOR STIMULATING THE VAGUSNERVS
TW200502221A (en) 2002-10-03 2005-01-16 Astrazeneca Ab Novel lactams and uses thereof
US7439231B2 (en) * 2003-02-14 2008-10-21 Provid Pharmaceuticals, Inc. Inhibitors of antigen presentation by MHC class II molecules and methods of use thereof
JP2006520396A (ja) * 2003-03-14 2006-09-07 アストラゼネカ・アクチエボラーグ 新規なラクタム及びその使用
TWI356821B (en) * 2003-12-01 2012-01-21 Cambridge Entpr Ltd Anti-inflammatory agents
WO2009073168A1 (en) * 2007-12-03 2009-06-11 Provid Pharmaceuticals, Inc. Inhibitors of antigen presentation by mhc class ii molecules and methods of use thereof

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4474778A (en) 1983-11-09 1984-10-02 E. R. Squibb & Sons, Inc. Lactam containing compounds, their pharmaceutical compositions and method of use
DE3711335A1 (de) 1987-04-03 1988-10-20 Merck Patent Gmbh Aminosaeurederivate
US5223485A (en) 1989-01-31 1993-06-29 Abbott Laboratories Anaphylatoxin-receptor ligands
WO1992002543A1 (en) * 1990-08-01 1992-02-20 Cytel Corporation Novel immunosuppressant peptides
DE4034829A1 (de) 1990-11-02 1992-05-07 Merck Patent Gmbh Cyclopeptide
AU2468392A (en) 1991-08-29 1993-04-05 Cytel Corporation Novel immunosuppressants
DK0644197T3 (da) 1993-06-04 1999-06-07 Vertex Pharma Peptidphosphinyloxymethylketoner som inhibitorer af interleukin-1beta-konverterende enzymer
AU698962B2 (en) 1993-09-14 1998-11-12 Epimmune, Inc. Alteration of immune response using pan DR-binding peptides
AU2238395A (en) 1994-04-01 1995-10-23 Immulogic Pharmaceutical Corporation Haptenated peptides and uses thereof
JPH10508035A (ja) 1995-03-24 1998-08-04 モレキュメティックス リミテッド βシート模倣物およびプロテアーゼインヒビターとしてのその使用
WO1997016425A1 (en) 1995-10-30 1997-05-09 Merck & Co., Inc. Novel inhibitors of peptide binding to mhc class ii proteins
US5817757A (en) * 1995-10-30 1998-10-06 Merck & Co., Inc. Inhibitors of peptide binding to MHO class II proteins
US5719296A (en) 1995-10-30 1998-02-17 Merck & Co., Inc. Pseudopeptide lactam inhibitors of peptide binding to MHC class II proteins
US5840835A (en) * 1995-10-30 1998-11-24 Merck & Co., Inc. Inhibitors of peptide binding to MHC class II proteins
GB9702377D0 (en) 1996-02-23 1997-03-26 Zeneca Ltd Peptide derivatives

Also Published As

Publication number Publication date
EP0932618A1 (en) 1999-08-04
DE69726743T2 (de) 2004-10-14
ZA979338B (en) 1998-04-20
US6207644B1 (en) 2001-03-27
TW492868B (en) 2002-07-01
WO1998017680A1 (en) 1998-04-30
GB9621836D0 (en) 1996-12-11
EP0932618B1 (en) 2003-12-10
AU4633097A (en) 1998-05-15
DE69726743D1 (de) 2004-01-22
ATE256145T1 (de) 2003-12-15

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