JP2001507338A - 疾患を治療するために同時投与されるアンドロゲン物質とビスホスホン酸物質 - Google Patents

疾患を治療するために同時投与されるアンドロゲン物質とビスホスホン酸物質

Info

Publication number
JP2001507338A
JP2001507338A JP52475398A JP52475398A JP2001507338A JP 2001507338 A JP2001507338 A JP 2001507338A JP 52475398 A JP52475398 A JP 52475398A JP 52475398 A JP52475398 A JP 52475398A JP 2001507338 A JP2001507338 A JP 2001507338A
Authority
JP
Japan
Prior art keywords
androgen
disease
bisphosphonic acid
pharmaceutically acceptable
testosterone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP52475398A
Other languages
English (en)
Japanese (ja)
Inventor
シユミツト,アズリエル
ロダン,ギデオン
俊一 原田
Original Assignee
メルク エンド カンパニー インコーポレーテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9700697.7A external-priority patent/GB9700697D0/en
Application filed by メルク エンド カンパニー インコーポレーテッド filed Critical メルク エンド カンパニー インコーポレーテッド
Publication of JP2001507338A publication Critical patent/JP2001507338A/ja
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Rheumatology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP52475398A 1996-11-25 1997-11-21 疾患を治療するために同時投与されるアンドロゲン物質とビスホスホン酸物質 Pending JP2001507338A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US3173496P 1996-11-25 1996-11-25
US3234196P 1996-12-04 1996-12-04
GB60/032,341 1997-01-15
GB9700697.7 1997-01-15
GB60/031,734 1997-01-15
GBGB9700697.7A GB9700697D0 (en) 1997-01-15 1997-01-15 Combination of an androgen and a bisphosphonic acid in the prevention and/or treatment of diseases involving calcium or phosphate metabolism
PCT/US1997/021306 WO1998023274A1 (fr) 1996-11-25 1997-11-21 Agents androgene et bisphosphonique coadministres pour traiter des maladies

Publications (1)

Publication Number Publication Date
JP2001507338A true JP2001507338A (ja) 2001-06-05

Family

ID=27268672

Family Applications (1)

Application Number Title Priority Date Filing Date
JP52475398A Pending JP2001507338A (ja) 1996-11-25 1997-11-21 疾患を治療するために同時投与されるアンドロゲン物質とビスホスホン酸物質

Country Status (5)

Country Link
EP (1) EP0949928A4 (fr)
JP (1) JP2001507338A (fr)
AU (1) AU743121B2 (fr)
CA (1) CA2271664A1 (fr)
WO (1) WO1998023274A1 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005002590A1 (fr) * 2003-07-01 2005-01-13 Astellas Pharma Inc. Agent d'induction de croissance dans la masse osseuse
JP2017522373A (ja) * 2014-07-04 2017-08-10 オステオ−ファルマ・ベー・フェー 骨折及び骨欠損の治療において使用するための組成物及び製品

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR013994A1 (es) * 1998-10-30 2001-01-31 Gador Sa Procedimiento y preparaciones que modulan selectivamente la funcion del osteoblasto para la prevencion y tratamiento de las osteopatias fragilizantes.
WO2000028982A2 (fr) * 1998-11-19 2000-05-25 The Board Of Trustees For The University Of Arkansas Renforcement de la structure osseuse a l'aide de diphosphonates selectionnes
US6605591B1 (en) 1999-11-12 2003-08-12 Genelabs Technologies, Inc. Treatment of subnormal bone mineral density

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2113848C1 (ru) * 1991-02-26 1998-06-27 Норвич Итон Фармасьютикалз, Инк. Способ лечения остеопороза, композиция для лечения остеопороза, применение активно действующего на кости фосфоната и эстрогенного гормона для лечения остеопороза
JP2746041B2 (ja) * 1992-02-14 1998-04-28 三菱化学株式会社 新規なステロイド誘導体
DE4218292C1 (de) * 1992-06-03 1994-02-03 Mattern Et Partner Pharmazeuti Verwendung eines Arzneimittels mit einem Gehalt an Mestanolon und/oder 4-Chlor-1-dehydromethyltestosteron
WO1994014455A1 (fr) * 1992-12-23 1994-07-07 Merck & Co., Inc. Therapie utilisant des bisphosphonates et des ×strogenes en vue de traiter et de prevenir la resorption osseuse
US5284841A (en) * 1993-02-04 1994-02-08 Merck & Co., Inc. Benzo-fused lactams promote release of growth hormone
US5547685A (en) * 1995-05-16 1996-08-20 Eli Lilly And Company Methods for inhibiting bone loss with vanadyl sulfate

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005002590A1 (fr) * 2003-07-01 2005-01-13 Astellas Pharma Inc. Agent d'induction de croissance dans la masse osseuse
JP2017522373A (ja) * 2014-07-04 2017-08-10 オステオ−ファルマ・ベー・フェー 骨折及び骨欠損の治療において使用するための組成物及び製品
JP2020143096A (ja) * 2014-07-04 2020-09-10 オステオ−ファルマ・ベー・フェー 骨折及び骨欠損の治療において使用するための組成物及び製品

Also Published As

Publication number Publication date
WO1998023274A1 (fr) 1998-06-04
CA2271664A1 (fr) 1998-06-04
EP0949928A1 (fr) 1999-10-20
AU7408698A (en) 1998-06-22
AU743121B2 (en) 2002-01-17
EP0949928A4 (fr) 2000-09-13

Similar Documents

Publication Publication Date Title
JP3113269B2 (ja) 骨粗鬆症治療剤
US8188066B2 (en) Medical uses of a selective estrogen receptor modulator in combination with sex steroid precursors
US4396615A (en) Method of treating androgen-related disorders
SE463074B (sv) Anvaendning av aromatashaemmare och antiandrogener foer framstaellning av laekemedel foer profylax och terapi av benign prostatahyperplasi
US8389548B2 (en) Medical uses of a selective estrogen receptor modulator in combination with sex steroid precursors
JPH05508155A (ja) ヒト前立腺腺癌の治療方法
US6376477B2 (en) Combination of an agent that binds to the androgen receptor and a bisphosphonic acid in the prevention and/or treatment of diseases involving calcium or phosphate metabolism
AU784160B2 (en) Treatment of subnormal bone mineral density
JP2001507338A (ja) 疾患を治療するために同時投与されるアンドロゲン物質とビスホスホン酸物質
JP2003292453A (ja) 骨疾患治療用医薬複合剤
JP2002522389A (ja) 異常骨吸収を治療又は予防するためのnk−1受容体アンタゴニストの使用
AU2011253842B2 (en) Medical Uses of a Selective Estrogen Receptor Modulator in Combination with Sex Steroid Precursors
ZA200203527B (en) Treatment of subnormal bone mineral density.