JP2001505883A5 - - Google Patents
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- Publication number
- JP2001505883A5 JP2001505883A5 JP1998525818A JP52581898A JP2001505883A5 JP 2001505883 A5 JP2001505883 A5 JP 2001505883A5 JP 1998525818 A JP1998525818 A JP 1998525818A JP 52581898 A JP52581898 A JP 52581898A JP 2001505883 A5 JP2001505883 A5 JP 2001505883A5
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3279296P | 1996-12-06 | 1996-12-06 | |
| US60/032,792 | 1996-12-06 | ||
| US4266097P | 1997-04-04 | 1997-04-04 | |
| US60/042,660 | 1997-04-04 | ||
| US5300197P | 1997-06-26 | 1997-06-26 | |
| US60/053,001 | 1997-06-26 | ||
| PCT/US1997/022289 WO1998024805A1 (en) | 1996-12-06 | 1997-12-05 | INHIBITORS OF INTERLEUKIN-1β CONVERTING ENZYME |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2001505883A JP2001505883A (ja) | 2001-05-08 |
| JP2001505883A5 true JP2001505883A5 (https=) | 2005-08-11 |
| JP4274584B2 JP4274584B2 (ja) | 2009-06-10 |
Family
ID=27364225
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP52581898A Expired - Lifetime JP4274584B2 (ja) | 1996-12-06 | 1997-12-05 | インターロイキン−1β変換酵素のインヒビター |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US6329365B1 (https=) |
| EP (1) | EP0944645B1 (https=) |
| JP (1) | JP4274584B2 (https=) |
| AT (1) | ATE290545T1 (https=) |
| AU (1) | AU5896098A (https=) |
| CA (1) | CA2274249A1 (https=) |
| DE (1) | DE69732712T2 (https=) |
| ES (1) | ES2239788T3 (https=) |
| PT (1) | PT944645E (https=) |
| WO (1) | WO1998024805A1 (https=) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0944645B1 (en) * | 1996-12-06 | 2005-03-09 | Vertex Pharmaceuticals Incorporated | INHIBITORS OF INTERLEUKIN-1beta CONVERTING ENZYME |
| US20010049381A1 (en) | 1997-06-04 | 2001-12-06 | Gpl Nil Holdings, Inc., | Pyrrolidine derivative hair growth compositions and uses |
| US5945441A (en) | 1997-06-04 | 1999-08-31 | Gpi Nil Holdings, Inc. | Pyrrolidine carboxylate hair revitalizing agents |
| US6184210B1 (en) * | 1997-10-10 | 2001-02-06 | Cytovia, Inc. | Dipeptide apoptosis inhibitors and the use thereof |
| ATE315394T1 (de) | 1997-11-10 | 2006-02-15 | Bristol Myers Squibb Co | Benzothiazole als protein tyrosin-kinase inhibitoren |
| US6331537B1 (en) | 1998-06-03 | 2001-12-18 | Gpi Nil Holdings, Inc. | Carboxylic acids and carboxylic acid isosteres of N-heterocyclic compounds |
| IL140040A0 (en) | 1998-06-03 | 2002-02-10 | Guilford Pharm Inc | N-linked sulfonamides of n-heterocyclic carboxylic acids or carboxylic acid isosteres |
| US7338976B1 (en) | 1998-08-14 | 2008-03-04 | Gpi Nil Holdings, Inc. | Heterocyclic esters or amides for vision and memory disorders |
| US6395758B1 (en) | 1998-08-14 | 2002-05-28 | Gpi Nil Holdings, Inc. | Small molecule carbamates or ureas for vision and memory disorders |
| FR2782997A1 (fr) * | 1998-09-08 | 2000-03-10 | Hoechst Marion Roussel Inc | Nouveaux derives de la benzodiazepinone, procede de preparation et intermediaires de ce procede, application a titre de medicaments et compositions pharmaceutiques les renfermant |
| US6462072B1 (en) | 1998-09-21 | 2002-10-08 | Gpi Nil Holdings, Inc. | Cyclic ester or amide derivatives |
| US7253169B2 (en) | 1999-11-12 | 2007-08-07 | Gliamed, Inc. | Aza compounds, pharmaceutical compositions and methods of use |
| EP1244670B1 (en) | 1999-12-21 | 2006-03-08 | MGI GP, Inc. | Hydantoin derivative compounds, pharmaceutical compositions, and methods of using same |
| WO2002066063A1 (en) * | 2001-02-23 | 2002-08-29 | Nippon Organon K.K. | Remedies for metabolic bone diseases |
| DE10129715A1 (de) * | 2001-06-22 | 2003-01-02 | Bayer Ag | Thiazolylamide |
| US7001899B2 (en) * | 2002-06-10 | 2006-02-21 | The Procter & Gamble Company | Interleukin converting enzyme inhibitors |
| ES2422193T3 (es) | 2002-06-28 | 2013-09-09 | Life Technologies Corp | Métodos para restaurar el repertorio inmune en pacientes con defectos inmunológicos relacionados con la autoinmunidad y trasplante de órganos o de células madre hematopoyéticas |
| US7060698B2 (en) * | 2003-05-19 | 2006-06-13 | Hoffmann-La Roche Inc. | Benzoxazepinone derivatives |
| WO2005115362A1 (en) * | 2004-05-15 | 2005-12-08 | Vertex Pharmaceuticals Incorporated | Treating seizures using ice inhibitors |
| BRPI0520554A2 (pt) | 2005-09-19 | 2009-06-13 | Arrow Therapeutics Ltd | uso de uma benzodiazepina ou um sal farmaceuticamente aceitável do mesmo, método para tratar ou prevenir uma infecção por hcv em um paciente, derivado de benzodiazepina ou um sal famaceuticamente aceitável do mesmo, e, composição farmacêutica |
| US9556426B2 (en) | 2009-09-16 | 2017-01-31 | Celgene Avilomics Research, Inc. | Protein kinase conjugates and inhibitors |
| JP2013516422A (ja) | 2009-12-30 | 2013-05-13 | アビラ セラピューティクス, インコーポレイテッド | タンパク質のリガンド−指向性共有的修飾 |
| US9956260B1 (en) | 2011-07-22 | 2018-05-01 | The J. David Gladstone Institutes | Treatment of HIV-1 infection and AIDS |
| US20230135030A1 (en) | 2018-11-26 | 2023-05-04 | Baseline Global, Inc. | Methods, Systems, and a Kit for Diagnosis, Detection, Monitoring & Treatment of Traumatic Brain Injury |
| WO2026082873A1 (en) | 2024-10-17 | 2026-04-23 | Institut National de la Santé et de la Recherche Médicale | Use of caspase-1 inhibitors for treating ineffective erythropoiesis in patients suffering from sickle cell disease |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4970207A (en) * | 1988-07-07 | 1990-11-13 | Fujisawa Pharmaceutical Company, Ltd. | Benzodiazepine derivatives |
| AU6909194A (en) * | 1993-05-14 | 1994-12-12 | Board Of Regents, The University Of Texas System | Preparation of n-cyanodithioimino-carbonates and 3-mercapto-5-amino-1h-1,2,4-triazole |
| US5580979A (en) * | 1994-03-15 | 1996-12-03 | Trustees Of Tufts University | Phosphotyrosine peptidomimetics for inhibiting SH2 domain interactions |
| US5716929A (en) * | 1994-06-17 | 1998-02-10 | Vertex Pharmaceuticals, Inc. | Inhibitors of interleukin-1β converting enzyme |
| US5852010A (en) * | 1996-04-03 | 1998-12-22 | Merck & Co., Inc. | Inhibitors of farnesyl-protein transferase |
| EP0944645B1 (en) * | 1996-12-06 | 2005-03-09 | Vertex Pharmaceuticals Incorporated | INHIBITORS OF INTERLEUKIN-1beta CONVERTING ENZYME |
-
1997
- 1997-12-05 EP EP97954531A patent/EP0944645B1/en not_active Expired - Lifetime
- 1997-12-05 AU AU58960/98A patent/AU5896098A/en not_active Abandoned
- 1997-12-05 CA CA002274249A patent/CA2274249A1/en not_active Abandoned
- 1997-12-05 JP JP52581898A patent/JP4274584B2/ja not_active Expired - Lifetime
- 1997-12-05 DE DE69732712T patent/DE69732712T2/de not_active Expired - Lifetime
- 1997-12-05 ES ES97954531T patent/ES2239788T3/es not_active Expired - Lifetime
- 1997-12-05 PT PT97954531T patent/PT944645E/pt unknown
- 1997-12-05 AT AT97954531T patent/ATE290545T1/de not_active IP Right Cessation
- 1997-12-05 WO PCT/US1997/022289 patent/WO1998024805A1/en not_active Ceased
-
1999
- 1999-06-04 US US09/326,495 patent/US6329365B1/en not_active Expired - Fee Related
-
2001
- 2001-10-23 US US10/035,850 patent/US6573259B2/en not_active Expired - Fee Related
-
2003
- 2003-04-25 US US10/424,576 patent/US6974809B2/en not_active Expired - Fee Related