JP2001503400A5 - - Google Patents

Download PDF

Info

Publication number
JP2001503400A5
JP2001503400A5 JP1998519424A JP51942498A JP2001503400A5 JP 2001503400 A5 JP2001503400 A5 JP 2001503400A5 JP 1998519424 A JP1998519424 A JP 1998519424A JP 51942498 A JP51942498 A JP 51942498A JP 2001503400 A5 JP2001503400 A5 JP 2001503400A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP1998519424A
Other languages
English (en)
Japanese (ja)
Other versions
JP2001503400A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US1997/018235 external-priority patent/WO1998017645A1/en
Publication of JP2001503400A publication Critical patent/JP2001503400A/ja
Publication of JP2001503400A5 publication Critical patent/JP2001503400A5/ja
Withdrawn legal-status Critical Current

Links

JP51942498A 1996-10-22 1997-10-20 マトリックス・メタロプロテイナーゼ阻害剤としてのα―アミノスルホニルヒドロキサム酸類 Withdrawn JP2001503400A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US2958596P 1996-10-22 1996-10-22
US60/029,585 1996-10-22
PCT/US1997/018235 WO1998017645A1 (en) 1996-10-22 1997-10-20 α-AMINO SULFONYL HYDROXAMIC ACIDS AS MATRIX METALLOPROTEINASE INHIBITORS

Publications (2)

Publication Number Publication Date
JP2001503400A JP2001503400A (ja) 2001-03-13
JP2001503400A5 true JP2001503400A5 (https=) 2005-06-16

Family

ID=21849807

Family Applications (1)

Application Number Title Priority Date Filing Date
JP51942498A Withdrawn JP2001503400A (ja) 1996-10-22 1997-10-20 マトリックス・メタロプロテイナーゼ阻害剤としてのα―アミノスルホニルヒドロキサム酸類

Country Status (9)

Country Link
US (1) US5804593A (https=)
EP (1) EP0934267B1 (https=)
JP (1) JP2001503400A (https=)
AT (1) ATE212619T1 (https=)
AU (1) AU4812697A (https=)
CA (1) CA2268418A1 (https=)
DE (1) DE69710204T2 (https=)
ES (1) ES2171905T3 (https=)
WO (1) WO1998017645A1 (https=)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9702088D0 (en) 1997-01-31 1997-03-19 Pharmacia & Upjohn Spa Matrix metalloproteinase inhibitors
NZ336840A (en) * 1997-02-03 2001-01-26 Pfizer Prod Inc Arylsulfonylamino hydroxamic acid derivatives useful in the treatment of tumor necrosis factor and matrix metalloproteinase mediated diseases
CA2298617A1 (en) 1997-07-31 1999-02-11 Yetunde Olabisi Taiwo Acyclic metalloprotease inhibitors
WO2000037433A1 (en) * 1998-12-18 2000-06-29 Abbott Laboratories Inhibitors of matrix metalloproteinases
US6277885B1 (en) 1999-01-27 2001-08-21 American Cyanamid Company Acetylenic aryl sulfonamide and phosphinic acid amide hydroxamic acid TACE inhibitors
US6313123B1 (en) 1999-01-27 2001-11-06 American Cyanamid Company Acetylenic sulfonamide thiol tace inhibitors
US6753337B2 (en) 1999-01-27 2004-06-22 Wyeth Holdings Corporation Alkynyl containing hydroxamic acid compounds as matrix metalloproteinase/tace inhibitors
US6225311B1 (en) 1999-01-27 2001-05-01 American Cyanamid Company Acetylenic α-amino acid-based sulfonamide hydroxamic acid tace inhibitors
US6946473B2 (en) * 1999-01-27 2005-09-20 Wyeth Holdings Corporation Preparation and use of acetylenic ortho-sulfonamido and phosphinic acid amido bicyclic heteroaryl hydroxamic acids as TACE inhibitors
US6358980B1 (en) 1999-01-27 2002-03-19 American Cyanamid Company Alkynyl containing hydroxamic acid compounds as matrix metalloproteinase/tace inhibitors
US6340691B1 (en) 1999-01-27 2002-01-22 American Cyanamid Company Alkynyl containing hydroxamic acid compounds as matrix metalloproteinase and tace inhibitors
US6762178B2 (en) 1999-01-27 2004-07-13 Wyeth Holdings Corporation Acetylenic aryl sulfonamide and phosphinic acid amide hydroxamic acid TACE inhibitors
US6200996B1 (en) 1999-01-27 2001-03-13 American Cyanamid Company Heteroaryl acetylenic sulfonamide and phosphinic acid amide hydroxamic acid tace inhibitors
US6326516B1 (en) 1999-01-27 2001-12-04 American Cyanamid Company Acetylenic β-sulfonamido and phosphinic acid amide hydroxamic acid TACE inhibitors
BR0008716A (pt) 1999-03-03 2002-09-24 Procter & Gamble Inibidores de metaloprotease contendo alquenil ou alquinil
MXPA01008857A (es) 1999-03-03 2002-07-02 Procter & Gamble Inhibidores de metaloproteasa dihetero sustituidos.
SE0100902D0 (sv) * 2001-03-15 2001-03-15 Astrazeneca Ab Compounds
SE0100903D0 (sv) * 2001-03-15 2001-03-15 Astrazeneca Ab Compounds
BR0213736A (pt) * 2001-11-01 2004-10-19 Wyeth Corp ácidos hidroxâmicos de sulfonamida de arila alênica como metaloproteinase matriz e inibidores de tace
SE0103710D0 (sv) * 2001-11-07 2001-11-07 Astrazeneca Ab Compounds
KR100701811B1 (ko) 2002-05-29 2007-04-02 머크 앤드 캄파니 인코포레이티드 탄저병의 치료 및 치사 인자의 억제에 유용한 화합물
SE0202539D0 (sv) * 2002-08-27 2002-08-27 Astrazeneca Ab Compounds
GB0221246D0 (en) * 2002-09-13 2002-10-23 Astrazeneca Ab Compounds
US7199155B2 (en) * 2002-12-23 2007-04-03 Wyeth Holdings Corporation Acetylenic aryl sulfonate hydroxamic acid TACE and matrix metalloproteinase inhibitors
AU2003300076C1 (en) 2002-12-30 2010-03-04 Angiotech International Ag Drug delivery from rapid gelling polymer composition
BRPI0407587A (pt) * 2003-02-18 2006-02-14 Pfizer inibidores do vìrus da hepatite c, composições e tratamentos que os utilizam
JP4790594B2 (ja) * 2003-02-25 2011-10-12 トポターゲット ユーケー リミテッド Hdacインヒビターとしての、二環式ヘテロアリール基を含むヒドロキサム酸化合物
AU2005250351A1 (en) 2004-05-11 2005-12-15 Merck & Co., Inc. Process for making n-sulfonated-amino acid derivatives
SE0401762D0 (sv) * 2004-07-05 2004-07-05 Astrazeneca Ab Novel compounds
US7648992B2 (en) 2004-07-05 2010-01-19 Astrazeneca Ab Hydantoin derivatives for the treatment of obstructive airway diseases
ITFI20040174A1 (it) * 2004-08-03 2004-11-03 Protera S R L Derivati arilsolfonammidici dell'acido idrossammico ad azione inibitoria di metalloproteinasi
US20100003276A1 (en) * 2004-12-07 2010-01-07 Hermes Jeffery D Methods for treating anthrax and inhibiting lethal factor
SE0403086D0 (sv) * 2004-12-17 2004-12-17 Astrazeneca Ab Compounds
SE0403085D0 (sv) * 2004-12-17 2004-12-17 Astrazeneca Ab Novel componds
TW200831488A (en) * 2006-11-29 2008-08-01 Astrazeneca Ab Novel compounds
CA3082972C (en) 2017-11-27 2022-10-11 Council Of Scientific & Industrial Research Indole (sulfomyl) n-hydroxy benzamide derivatives as selective hdac inhibitors
WO2026015506A1 (en) * 2024-07-11 2026-01-15 Purdue Research Foundation Dual inhibitors for hdac3 and hiv-1 pr

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5455258A (en) * 1993-01-06 1995-10-03 Ciba-Geigy Corporation Arylsulfonamido-substituted hydroxamic acids
US5646167A (en) * 1993-01-06 1997-07-08 Ciba-Geigy Corporation Arylsulfonamido-substituted hydroxamix acids
CA2193691A1 (en) * 1994-06-22 1995-12-28 Andrew Miller Metalloproteinase inhibitors
EP0800449B1 (de) * 1995-01-03 1999-07-07 Reinhard Eichenberger Verfahren und vorrichtung zur herstellung von verstärkungseinlagen für werkstoffverbunde, insbesondere schleif- oder trennscheiben
US5863949A (en) * 1995-03-08 1999-01-26 Pfizer Inc Arylsulfonylamino hydroxamic acid derivatives
ES2153031T4 (es) * 1995-04-20 2001-05-16 Pfizer Derivados del acido arilsulfonil hidroxamico como inhibidores de mmp y tnf.
KR980009238A (ko) * 1995-07-28 1998-04-30 우에노 도시오 설포닐아미노산 유도체
PT757984E (pt) * 1995-08-08 2003-02-28 Ono Pharmaceutical Co Derivados de acido hidroxamico uteis para inibir a gelatinase
US6207672B1 (en) * 1995-11-13 2001-03-27 Aventis Pharma Deutschland Gmbh Cyclic and heterocyclic N-substituted α-iminohydroxamic and carboxyclic acids
BR9707010B1 (pt) * 1996-01-23 2009-05-05 compostos, composição farmacêutica e composições para inibir metaloproteinase e colagenase do tipo iv.

Similar Documents

Publication Publication Date Title
JP2000502280A5 (https=)
JP2000501771A5 (https=)
JP2000517304A5 (https=)
JP2000501599A5 (https=)
JP2000501018A5 (https=)
JP2000500076A5 (https=)
JP2000501324A5 (https=)
JP2000502472A5 (https=)
JP2000501338A5 (https=)
JP2000501825A5 (https=)
JP2000500874A5 (https=)
JP2001510598A5 (https=)
JP2000502425A5 (https=)
JP2000502485A5 (https=)
JP2000502568A5 (https=)
JP2000501774A5 (https=)
JP2000500912A5 (https=)
JP2000502570A5 (https=)
JP2000501876A5 (https=)
JP2000501744A5 (https=)
JP2000501229A5 (https=)
JP2000502316A5 (https=)
JP2000500857A5 (https=)
JP2000502714A5 (https=)
JP2000500184A5 (https=)