JP2001247446A - Cleaning agent with deep sea water - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain a cleaning agent capable of easily cleaning the inner oral cavity or the inner nasal cavity when going out and excellent in feeling of use. SOLUTION: A cleaning agent composed of deep sea water and an active ingredient is disclosed. Cetylpyridinium chloride, benzethonium chloride, benzalkonium chloride, povidone iodine, dequalinium chloride, chlorhexidine gluconate, dipotassium glycyrrhizinate, naphazoline hydrochloride, chlorpheniramine maleate, lidocaine hydrochloride, zinc sulfate, menthol, camphor, peppermint oil, eucalyptus oil, fennel oil, cinnamon oil, clove oil, or the like, is disclosed as the active ingredient. Especially, a cleaning agent packed with an amount for use every one time or an aerosol-type agent is disclosed.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

TECHNICAL FIELD The present invention relates to a detergent comprising a mixture of deep water or a mixture of deep water and an active ingredient.
In particular, the present invention relates to a cleaning agent in which the used amount is packaged once or aerosol type.

[0002]

2. Description of the Related Art Conventionally, a mouthwash is prepared by putting a few drops or 2 to 4 mL of a drug solution into a cup, diluting it with a predetermined amount of water to prepare a mouthwash, and washing the mouth, especially the throat gargle. Often. In the case of washing the oral cavity at home, it is easy to prepare a mouthwash, and the oral cavity can be easily and frequently cleaned. Was not at hand and it was difficult to prepare a mouthwash, so that the mouth could not be easily washed. Also, with regard to nasal washing, it is easily implemented in homes and medical facilities such as hospitals,
At present, there is no cleaning agent for easily cleaning the nasal cavity when going out.

As a diluent for preparing a mouthwash, tap water and the like are exclusively used, and tap water is also used for washing the nasal cavity. However, the thus-prepared gargle, nasal rinse, and the like are irritated by trace components contained in tap water, and the feeling of use is not always sufficient. Therefore, although there has been a demand for the development of a cleaning agent having a good feeling of use, it has not yet been sufficiently studied.

[0004]

SUMMARY OF THE INVENTION In view of this situation, an object of the present invention is to provide a cleaning agent which can easily clean the inside of the mouth or the nasal cavity when going out, and which is excellent in the feeling of use. And

[0005]

Means for Solving the Problems The present invention for solving the above problems is a cleaning agent containing deep water or a combination of deep water and an active ingredient.

[0006] Among them, the cleaning agent provided by the present invention is:
It is a cleaning agent that has been packaged once each time, or an aerosol-type cleaning agent. Especially when used as a mouthwash for cleaning the oral cavity or the nasal cavity, there is no need for dilution, and once each Cleaning agent packaged for easy use.

[0007]

DESCRIPTION OF THE PREFERRED EMBODIMENTS Deep water used in the cleaning agent of the present invention is generally seawater having a depth of 200 meters or less. Such characteristics of deep water include low-temperature characteristics, clean water characteristics, eutrophication characteristics including a large amount of nitrogen, silicon, and phosphorus,
There are mineral properties with a good balance of mineral components. The cleaning agent provided by the present invention utilizes the mineral properties of the deep water, and is characterized in that by mixing the deep water into the cleaning agent, the cleaning agent has an excellent usability. . That is, the cleaning agent provided by the present invention was easy to adapt to mucous membranes and skin, alleviated irritation to mucous membranes and skin, and showed a fresh feeling in use in addition to a moist feeling even after washing.

In this case, the mixing amount of the deep water is 0.1% to 100% as a detergent, preferably 1% to 70%.
And more preferably 5% to 50%.

On the other hand, the active ingredients which can be added to the detergent of the present invention include bactericidal disinfectants such as cetylpyridinium chloride, benzethonium chloride, benzerkonium chloride, popidone iodine, decalinium chloride, chlorhexidine gluconate; dipotassium glycyrrhizinate; Anti-inflammatory and anti-allergic agents such as epsilon aminocaproic acid;
Peripheral vasoconstrictors such as naphazoline hydrochloride and tetrahydrozoline hydrochloride; antihistamines such as chlorpheniramine maleate and diphenhydramine hydrochloride; local anesthetics such as lidocaine hydrochloride; astringents such as zinc sulfate and allantoin; menthol, camphor, peppermint oil and eucalyptus oil , Fennel oil, cinnamon oil, clove oil and the like, and one or more of these active ingredients can be blended.

[0010] The cleaning agent of the present invention can be used as
It is packaged in single doses so that the mouth or nasal cavity can be easily cleaned when going out. Specifically, an oral gargle in the form of a bottle pack or a stick package, or a nasal rinse (washing) Nasal pills). In that case, the usage amount of gargle is 3mL
３０30 mL, preferably 5-20 mL. The single use amount of the nasal wash is 0.5 mL to 20 mL, preferably 2 mL to 10 mL.

[0011] The cleaning agent of the present invention can also be used as an aerosol type form which is convenient to carry and use. The application of such an aerosol-type cleaning agent has an advantage that it can be used not only for the oral cavity and the nasal cavity but also for cleaning the skin and the like. As a method for producing these bottle packs, stick packaging, or aerosol-type cleaning agents, the method used in conventional production is used as it is.

The cleaning agent provided by the present invention is based on a constitution in which deep water is blended with a base component, and the base component includes various bases usually used in gargles. Ingredients and various base components used for nasal drops and wounds can be used. Such base components include, for example, polyhydric alcohols such as glycerin, xylitol and sorbitol, lower alcohols such as ethanol and isopropanol, organic acids such as citric acid and lactic acid and salts thereof, sodium pyrrolidone carboxylate, purified water , Sodium hyaluronate, chondroitin sulfate, pullulan, dextran, macrogol, polyoxyethylene polyoxypropylene glycols,
Examples thereof include cellulose derivatives such as hydroxypropyl cellulose.

Further, in addition to the above base components, lauromacrogol and polyoxyethylene hydrogenated castor oil as surfactants, and alkyl esters of paraoxybenzoic acid such as methyl paraoxybenzoate as preservatives, chlorobutanol, chloride Quaternary ammonium ions such as benzalkonium, phenethyl alcohol, etc., borate buffer, phosphate buffer, acetate buffer, citrate buffer, etc. as buffers, hydrochloric acid, phosphoric acid, sulfuric acid, etc. as pH adjusters And inorganic bases such as sodium hydroxide, potassium hydroxide and sodium carbonate.

[0014] The cleaning agent of the present invention thus produced is blended with deep water, and is easy to adapt to mucous membranes and skin due to the characteristics of the mineral components of the deep water. A fresh feeling of use is recognized, and since the amount used is packaged once, or the aerosol type is used, the mouth or the nasal cavity can be easily washed when going out.

[0015]

EXAMPLES The present invention will now be described specifically with reference to examples, but the present invention is not limited to these examples.

Examples 1-3: Gargles Gargles were prepared according to the formulation shown in Table 1 below.

[0017]

[Table 1] (g)

Preparation method 15 g of glycerin is added to 30 g of deep water, and 2 g of xylitol and 1 g of lauromacrogol are dissolved under stirring.
In this solution, 0.02 g of menthol and 0.005 g of fennel oil were further dissolved, and then, 0.03 g of methyl paraoxybenzoate and 0.03 g of propyl paraoxybenzoate were dissolved.
After dissolving 02 g, the solution was made up to 100 mL with purified water and filtered to obtain the gargle of Example 1. In other examples, the preparation method of the same operation was carried out,
Obtained a mouthwash, nasal rinse or skin cleanser.

Examples 4 to 6: Nasal rinses Nasal rinses were prepared according to the formulation shown in Table 2 below.

[0020]

[Table 2] (g)

Examples 7 and 8: Skin cleansing agents Skin cleansing agents were prepared according to the formulations shown in Table 3 below.

[0022]

[Table 3] (g)

Example 9: Sensory test Five adult males (A to E) were used as volunteers, and the gargle of the present invention obtained in Example 1 and the nasal wash obtained in Example 4 were used as volunteers. A sensory test was performed. In addition, as Comparative Example 1 for the gargle of the present invention, one in which the deep water of the gargle of Example 1 was replaced with purified water was used, and as Comparative Example 2 for the nasal wash, only purified water was used. . Mouthwashes and nasal rinses evaluated as having a good feeling of use by the sensory test of five volunteers were marked with a circle.

The results are summarized in Table 4 below. The gargle and the nasal wash containing the deep water had a better use feeling than the comparative example (conventional product).

[0025]

[Table 4]

[0026]

As described above, the present invention relates to a cleaning agent containing deep water or a mixture of deep water and an active ingredient. In particular, the cleaning agent is packaged in a single use amount, or is made into an aerosol type. Provide things. ADVANTAGE OF THE INVENTION By this invention, it becomes possible to supply a portable and convenient washing | cleaning agent which can wash | clean an intraoral cavity, a nasal cavity, etc. easily at the time of going out, and also provides the washing | cleaning agent which was excellent in a feeling of use by mixing deep water. .

Continued on the front page (51) Int.Cl. ⁷ Identification symbol FI Theme coat II (Reference) A61K 31/14 A61K 31/14 4C088 31/155 31/155 4C206 31/167 31/167 31/4174 31/4174 31 / 4402 31/4402 31/4425 31/4425 31/4706 31/4706 31/704 31/704 31/755 31/755 33/30 33/30 35/08 35/08 35/78 35/78 Q C N 45 / 08 45/08 (72) Inventor Yoshinori Saiki 26 Misato, Toyama City, Toyama Prefecture Toa Pharmaceutical Co., Ltd. In-house (72) Inventor Satoshi Oguro 26 26 Misato Toyama City, Toyama Prefecture Toa Pharmaceutical Co., Ltd.In-house (72) Inventor Yamazaki Megumi 26 Togo, Toyama-shi, Toyama Toa Pharmaceutical Co., Ltd. In-house F-term (reference) 4C076 AA12 AA24 AA99 BB22 BB25 BB31 CC04 CC10 CC18 DD21 FF70 4C083 AA121 AA122 AB051 AB351 AC102 AC122 AC132 AC432 AC482 AC641 AC642 AC1 AC693 AC692 AC692 AD532 BB51 BB55 CC23 CC41 DD08 DD23 DD27 DD47 EE06 EE31 EE50 4C084 AA16 AA27 MA13 MA17 NA10 NA20 ZA342 ZA672 ZB312 ZB352 ZC801 4C086 AA01 AA02 BC17 BC21 BC38 EA19 FA03 MA02 MA03 MA 05 MA13 MA17 NA10 NA20 ZA34 ZA67 ZA89 ZB31 ZB35 4C087 AA01 AA02 BA01 BA10 MA02 MA05 MA13 MA17 MA57 MA59 MA63 NA14 ZA34 ZA67 ZA90 ZB31 ZB35 4C088 AB33 AB38 AB40 AB57 MA07 MA13 MA17 MA57 MA59 ZA34 Z20A20 ZA37 ZA29 CA09 CB24 FA41 FA42 GA31 HA31 MA02 MA03 MA33 MA37 MA77 MA79 MA83 NA10 NA20 ZA34 ZA67 ZA89 ZB31 ZB35

Claims (5)

[Claims] 1. A cleaning agent comprising deep water or a combination of deep water and an active ingredient. 2. The cleaning agent according to claim 1, wherein the mixing amount of the deep water is 0.1% to 100%. 3. An effective ingredient to be added is cetylpyridinium chloride, benzethonium chloride, benzerkonium chloride,
Group consisting of popidone iodine, decalinium chloride, chlorhexidine gluconate, dipotassium glycyrrhizinate, naphazoline hydrochloride, chlorpheniramine maleate, lidocaine hydrochloride, zinc sulfate, menthol, camphor, peppermint oil, eucalyptus oil, fennel oil, cauliflower oil, and clove oil The cleaning agent according to claim 1, which is at least one member selected from the group consisting of: 4. The cleaning agent according to claim 1, wherein the amount of use is packaged once or aerosol type. 5. The cleaning agent according to claim 1, which is used for cleaning the oral cavity, nasal cavity or limbs.