JP2001181175A - Cosmetic and quasi-drug - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain a cosmetic and a quasi-drug comprising ingredients which are safe when applied to the skin, have great improving actions on atopic dermatitis and are effective against skin roughening, xeroderma, etc. SOLUTION: As a result of investigations on screening of combinations of substances which have been regarded as effective against atopic dermatitis, utilized and confirmed in safety for human bodies and search on substances having utility values as the cosmetic and quasi-drug, it is found that the combination of a tea tree with ceramide has extreme effectiveness as the cosmetic and quasi-drug. Improving actions on atopic dermatitis, improving actions on skin roughening and improving actions on xeroderma are confirmed as confirmed effects.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention is a cosmetic which has a high effect of improving atopic dermatitis and is effective for rough skin, xerosis, etc.
Related to quasi-drugs.

[0002]

2. Description of the Related Art Tea trees are plants belonging to the family Myrtaceae, and the essential oil extracted therefrom is used as a folk remedy such as acne drugs. Ceramide is used as a constituent in the skin, and has been identified in types 1 to 6 and is widely used as a raw material for cosmetics.

[0003] Various substances are known as substances for improving atopic dermatitis as raw materials for cosmetics and quasi-drugs, but the effectiveness of several kinds of synergistic effects has not been confirmed. In addition, a substance that not only improves atopic dermatitis but also has other effects on the skin has been desired.

[0004]

SUMMARY OF THE INVENTION An object of the present invention is to provide cosmetics and medicaments which are safe when applied to the skin, have a large effect of improving atopic dermatitis, and contain effective ingredients for rough skin, xerosis etc. It is to provide quasi-products.

[0005]

Means for Solving the Problems In order to solve the above-mentioned problems, the present inventors have screened a combination of substances which have been used effectively for atopic dermatitis for many years and whose safety to the human body has been confirmed. Investigating and examining those that are valuable as cosmetics and quasi drugs.
As a result, they have found that the combination of tea tree and ceramide has a very effective effect as cosmetics and quasi-drugs. The confirmed effects were an atopic dermatitis improving effect, a rough skin improving effect, and a xeroderma improving effect.

That is, the present invention is a cosmetic and quasi-drug containing tea tree and ceramide.

This substance is used as a raw material for other cosmetics such as liquid oils such as squalane and jojoba oil, solid oils such as beeswax and cetyl alcohol, various activators, humectants such as glycerin and 1,3-butylene glycol and various chemicals. It can be added to adjust cosmetics and quasi-drugs of various dosage forms.
For example, a use form may be considered depending on the purpose, such as a lotion, a cream, an emulsion, a pack, and a face wash.

[0008]

EXAMPLES The following is an example of an actual use method, but the present invention is not limited to the example.

Example-1 Lotion Olive Oil 0.4 Tea Tree Oil 0.1 Polyoxyethylene (20EO) Sorbitan Monostearate 2.0 Polyoxyethylene (60EO) Hardened Castor Oil 2.0 Ethanol 5.0 Glycerin 5.0 Ceramide 0.1 Ethanol 10.0 1.0% Sodium hyaluronate solution 5.0 Purified water 70.4

Example-2 Cream A Squalane 20.0 Olive Oil 2.0 Mink Oil 1.0 Jojoba Oil 5.0 Tea Tree Oil 1.0 Beeswax 5.0 Cetostearyl Alcohol 2.0 Glycerin Monostearate 1.0 Sorbitan Monostearate 2.0 B Purified water 46.7 Polyoxyethylene (20EO) Sorbitan monostearate 2.0 Polyoxyethylene (60EO) hydrogenated castor oil 2.0 Glycerin 5.0 1.0% Hyaluronic Sodium acid solution 5.0 Ceramide 0.2 Methyl parahydroxybenzoate 0.1 A and B were each weighed, heated to 70 ° C., and A was gradually added to B with stirring, and then slowly stirred. 30
Cooled to ° C.

Usage test-1 Three women diagnosed with atopic dermatitis were divided into the right and left faces, one of which was used as Example-2 and the other was used as Comparative Example-1. I did a questionnaire. Comparative Example-1 is obtained by changing ceramide to water as compared with Example-2. The following table summarizes the results of the questionnaire as follows. Example is very good 3 Example is quite good 2 Somewhat better before experiment 1 No difference 0 Comparative example is slightly better -1 Comparative example is much better -2 Comparative example Is much better -3

[0012] No worsening of symptoms was observed.

Use test-2 The face of three women diagnosed with atopic dermatitis different from the use test-1 is divided into left and right faces, one of which is Example-2 and the other is of Comparative example-2, once a day. Have more than 3
A month later, we did a questionnaire. Comparative Example-2 is Example-
The tea tree was changed to water from 2. The following table summarizes the results of the questionnaire as follows. Example is very good 3 Example is quite good 2 Somewhat better before experiment 1 No difference 0 Comparative example is slightly better -1 Comparative example is much better -2 Comparative example Is much better -3

[0014] No worsening of symptoms was observed.

Usage Test-3 Example for the affected part of 10 women diagnosed with xeroderma
1 was applied and a questionnaire was given 3 months later. The following table summarizes the results of the questionnaire as follows. It was much better than before the experiment. 3 It was much better than before the experiment. 2 It was slightly better than before the experiment. 1 There was no difference. 0 It was slightly worse than before the experiment. -1 It was much worse than before the experiment. Deteriorated -3

[0016] No difference, no deterioration was observed.

Usage Test-4 The faces of ten women who were aware that their skin was rough were divided into left and right faces, one of which was used as Example-2 and the other as Comparative Example-3, and used at least once daily. A questionnaire was given three months later. Comparative Example-3 is different from Example-2 in that ceramide and tea tree oil were changed to water. The following table summarizes the results of the questionnaire as follows. Example is very good 3 Example is quite good 2 Somewhat better before experiment 1 No difference 0 Comparative example is slightly better -1 Comparative example is much better -2 Comparative example Is much better -3

[0018] No worsening of symptoms was observed.

[0019]

[Effect] Cosmetics containing both tea tree and ceramide have an atopic dermatitis ameliorating effect, a xeroderma ameliorating effect, and a rough skin improving effect. This was found to be stronger than tea trees and cosmetics containing ceramide alone.

Continued on the front page (51) Int.Cl. ⁷ Identification symbol FI Theme coat II (reference) A61P 17/00 A61P 17/00

Claims (1)

[Claims] 1. A cosmetic or quasi-drug containing any one or more solvent extracts of tea tree and one or more ceramides.