JP2001062595A - Pounder and mortar for tablet molding, and manufacture thereof - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a pounder and a mortar used for molding a source substance including a corrosive substance such as acidic powder into a tablet, with high hardness, high corrosion resistance and excellent mold releasing property. SOLUTION: This is a pounder and a mortar used when powdery, granular, gel-like, or high-viscosity liquid source substances are molded into a tablet. At least a molding part of the pounder and the mortar is composed of a Ni-Cr- Al base alloy including, for example, 25-60 wt.% Cr, 1-10 wt.% Al and the balance of substantially Ni. The pounders and the mortar for molding tablets are used as pounders 1, 2 and a mortar 3 of a tablet molding machine 10.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a tablet-forming punch and a die suitable for tablet-forming a raw material containing a corrosive substance such as an acidic powder, and a method for producing the same.

[0002]

2. Description of the Related Art Conventionally, raw materials such as powders and granules are compressed to produce pharmaceuticals, quasi-drugs, cosmetics, pesticides, feeds,
When molding tablets such as food, a mold set is used in which a die having a through hole according to the tablet shape, and a lower punch and an upper punch inserted into the through hole (a die hole) of the die are used. I have.
Various tableting machines are known as tableting machines using such a mold set (Japanese Patent Application Laid-Open Nos. 5-318198 and 7-85).
40, 9-122990, 9-206998, etc.). In a tableting machine, first, a raw material such as powder is filled in a die into which a lower punch has been inserted, and the raw material is compressed by an upper punch to form a desired tablet.

[0003] As described in Japanese Patent Application Laid-Open No. 7-8540, for example, alloy tool steel (for example, SKS2 or SK) is used for a tablet forming die set such as a punch and a die used for a tablet forming machine.
D11) or a cemented carbide mainly composed of a compound such as Mo or W. However, these conventional tablet-forming dies do not always provide satisfactory properties in terms of corrosion resistance and strength, and the problem that the life of the dies is greatly reduced depending on the properties of the raw materials occurs. I have.

For example, with the diversification of pharmaceutical products in recent years, it has become necessary to pressurize highly corrosive powders such as acidic powders. When a mold for forming a tablet made of a conventional alloy tool steel or the like is used for molding such an acidic powder, the surface of the mold is corroded early by the acidic powder. Corrosion of the mold surface causes a reduction in powder separation of the raw material powder, and further causes deterioration in strength. For this reason, when a highly corrosive powder such as an acidic powder is formed, the life of the tablet forming die set is significantly reduced.

[0005] Further, in order to improve the corrosion resistance of a tablet molding die made of alloy tool steel or the like, coating with chromium plating or the like has been attempted, but a sufficient effect can be obtained by peeling off the coating layer. It is not possible, and there is a problem that the releasability decreases. Further, the use of ceramic sintered bodies is also being studied, but the ceramics are broken down by the pressure and impact force during molding, and have not been put to practical use.

As a hot press die having excellent corrosion resistance, a die described in Japanese Patent Application Laid-Open No. 63-18031 has been proposed. This mold contains 20-50% by weight of Cr and 1.5% of Al.
9% by weight, with the balance substantially consisting of Ni,
It describes that it has a high hardness to a hot press at 500 to 800 ° C. and a press pressure of 500 to 2000 kg / cm ² and has a long service life without buckling. Also, in this publication,
It is also described that Ni is a component that improves corrosion resistance.

Further, Japanese Patent Application Laid-Open Nos. Sho 52-60217 and 55-14
JP-A-5142, JP-A-53-137767, JP-A-1-127640 and the like describe watch sides and decorative articles made of Ni-Cr-Al-based alloys, and these Ni-Cr-A
It is described that the 1-based alloy has high hardness and excellent corrosion resistance.

[0008]

As described above, as a tablet molding die set used for molding various tablets, etc.,
Conventionally, alloy tool steels such as SKS2 and SKD11 have been mainly used, but when used for forming highly corrosive raw materials such as acidic powder, the mold surface is corroded, and so on.
This causes a problem that the life of the mold set is significantly reduced. In the case of a mold set having a coating treatment on the surface, peeling of the coating layer and reduction in releasability become problems. Furthermore, the use of a ceramic sintered body causes destruction due to pressure and impact force during molding, and has not been put to practical use.

Although a mold using a Ni—Cr—Al alloy achieves high hardness during hot pressing, it is applicable to cold press molding at room temperature or the like or non-heat press molding. In particular, no consideration has been given to maintaining the releasability over a long period of time for tableting various raw materials having corrosive properties such as acidity using a punch and a die used in a tablet molding machine.

[0010] The present invention has been made to address such problems, and while maintaining the strength required for a tableting mold set such as a powder, is intended to improve the corrosion resistance to corrosive substances such as an acidic powder. It is an object of the present invention to provide a tablet-forming punch and a die and a method for producing the same, which make it possible to achieve a longer life of a mold set.

[0011]

According to the first aspect of the present invention, there is provided a tablet forming punch comprising a raw material containing at least one selected from powders, granules, gels, and high-viscosity liquids. A punch used for tablet molding, wherein at least a molding part in contact with the raw material is made of a Ni-Cr-Al-based alloy.

In the punch for tablet molding of the present invention, Ni-C
As described in claim 2, for example, an alloy containing 25 to 60% by weight of Cr, 1 to 10% by weight of Al, and substantially Ni is used as the r-Al alloy. N
As described in claim 3, the i-Cr-Al alloy is M
It may contain at least one element selected from n, Si, C and Mg in a range of 0.1% by weight or less, and may further contain an element which improves machinability and ductility. . In particular, as described in claim 4, M
Preferably, it contains at least one element selected from n, Si and Mg in a range of 0.1% by weight or less. In this specification, “X to Y” means “X or more and Y or less”.

[0013] The Ni-Cr-Al alloy used in the present invention has a Vickers hardness of 500 Hv or more, for example, as described in claim 5. It is excellent. Such N
As described in claim 6, the tablet forming punch made of an i-Cr-Al-based alloy is suitable for pressure-forming a corrosive substance such as an acidic powder, for example. In the tablet forming punch of the present invention, as described in claim 7, the surface roughness of the formed portion is preferably 1.6 μm or less in Ra.

According to the present invention, there is provided a tablet-forming die for use in tablet-forming a raw material containing at least one selected from powders, granules, gels and high-viscosity liquids. Wherein at least a molded part in contact with the raw material is made of a Ni-Cr-Al-based alloy.

In the tablet molding die of the present invention, Ni-C
As described in claim 9, the r-Al-based alloy is an alloy containing, for example, Cr in the range of 25 to 60% by weight, Al in the range of 1 to 10% by weight, and the balance substantially consisting of Ni. N
The i-Cr-Al based alloy is as described in claim 10,
It may contain at least one element selected from Mn, Si, C and Mg in a range of 0.1% by weight or less, and may further contain an element which improves machinability, ductility and the like. . In particular, as described in claim 11,
It preferably contains at least one element selected from Mn, Si and Mg in a range of 0.1% by weight or less.

The Ni-Cr-Al alloy used in the present invention has a Vickers hardness of 500 Hv or more, for example, as described in claim 12. It is excellent. The tablet-forming die of the present invention made of such a Ni-Cr-Al-based alloy is suitable for pressure-forming a corrosive substance such as, for example, an acidic powder. Further, in the tablet-forming die of the present invention, as described in claim 14, the surface roughness of the molded part is preferably 1.6 μm or less in Ra.

The method for producing a tablet-forming punch according to the present invention is, as described in claim 15, a method for tablet-forming a raw material containing at least one selected from powders, granules, gels and high-viscosity liquids. In manufacturing the punches used, Ni-
A step of solution-treating the Cr-Al-based alloy material;
The solution-treated Ni-
A step of roughly processing a Cr-Al-based alloy material to a shape larger than a predetermined punch size;
Subjecting the base alloy material to aging treatment;
finishing the i-Cr-Al-based alloy material to the predetermined punch size.

Further, in the method for manufacturing a tablet-forming punch according to the present invention, in the solution-treating step, the Ni-Cr-Al-based alloy material may be used in a temperature range of 1000 to 1350 ° C. It is characterized by cooling with water or oil after heat treatment at a temperature. Further, as set forth in claim 17, the Ni-Cr-Al-based alloy material is heat-treated at a temperature in the range of 500 to 950C in the aging treatment step.

The method for producing a tablet-forming die according to the present invention is, as described in claim 18, for tablet-forming a raw material containing at least one selected from powders, granules, gels and high-viscosity liquids. In producing the mortar used, Ni-
A step of solution-treating the Cr-Al-based alloy material;
The solution-treated Ni-
A step of roughly processing the Cr-Al-based alloy material to a shape larger than a predetermined die size;
Subjecting the base alloy material to aging treatment;
finishing the i-Cr-Al alloy material to the predetermined die size.

Further, in the method for producing a tablet-forming die according to the present invention, in the solution treatment step, the Ni-Cr-Al-based alloy material may be cooled to a temperature within a range of 1000 to 1350 ° C. It is characterized by cooling with water or oil after heat treatment at a temperature. Further, as described in claim 20, the Ni-Cr-Al-based alloy material is heat-treated at a temperature in the range of 500 to 950C in the aging treatment step.

The tablet-forming punch and die of the present invention use a Ni-Cr-Al-based alloy having high strength and high hardness and excellent corrosion resistance. In other words, by adding Cr or Al to Ni, which has essentially good corrosion resistance, and alloying it, it is possible to further improve the corrosion resistance, and by aging treatment, the γ phase, α phase, γ ′ phase, etc. High hardness can be obtained by complex precipitation.

According to such a Ni-Cr-Al alloy, the strength required for a tablet-forming punch and a tablet-forming die such as powders, granules, gels, high-viscosity liquids, and mixtures thereof are maintained. In addition, even when a highly corrosive substance such as an acidic powder is compression-molded, the progress of corrosion due to contact with the highly corrosive substance can be greatly suppressed. Therefore,
According to the present invention in which the Ni-Cr-Al-based alloy is used at least for the forming part, it is possible to achieve a longer life of the tablet forming punch and the tablet forming die. In addition, by applying such a tablet-forming punch and tablet-forming die, tablets can be formed stably over a long period of time, thereby improving the tablet-forming yield and reducing the molding cost. Becomes possible.

Further, since the above-mentioned Ni-Cr-Al-based alloy is excellent in the machinability after the solution treatment, the Ni-Cr-Al-based alloy material after the solution treatment is reduced to a predetermined size of a punch or a die. After rough processing into a slightly larger shape, by performing aging treatment and finish processing to a predetermined size, the above-mentioned characteristics of high strength and high corrosion resistance are stably obtained, while reducing the manufacturing cost of punches and dies and The dimensional accuracy can be improved.

The punch and die for tablet formation of the present invention are:
For example, a mill having a through hole filled with a raw material containing at least one selected from powder, granules, gel, and a high-viscosity liquid, and a pair of upper and lower inserts respectively inserted into the through hole of the mill from above and below It is used for a tablet press equipped with a punch and a pressurizing means for pressing a pair of upper and lower punches and compressing and forming a raw material filled in a die. Such a tablet press is used, for example, when press-forming a raw material containing a corrosive substance, and is particularly suitable as a tablet press for press-forming a raw material containing an acidic powder.

[0025]

Embodiments of the present invention will be described below.

FIGS. 1 and 2 are views showing a punch as an embodiment of the tablet-forming die set of the present invention.
1 shows an upper punch 1, and FIG. 2 shows a lower punch 2. The pair of upper and lower punches 1 and 2 are used when pressure-forming raw materials such as powder, granules, gels, high-viscosity liquids, and mixtures thereof in a tableting machine or the like described in detail below. For example, it is used together with a die (die) 3 as shown in FIG. The mortar 3 shown in FIG. 3 has a through hole (mortar hole) 3a filled with the raw material.

The punches 1 and 2 have forming portions 1a and 2a at their tips (punch tips) that come into contact with the raw material, respectively. The forming portions 1a and 2a have a shape that can be inserted into the die hole 3a. Have been. The heads 1b, 2 to which compressive force is applied are respectively applied to the ends of the punches 1, 2 on the opposite side to the molding portions 1a, 2a.
b is provided.

In such punches 1 and 2, at least the molded portions 1a and 2a are formed of a Ni-Cr-Al alloy. 1 and 2 show the punches 1 and 2 in which the entire punch including the molded portions 1a and 2a and the heads 1b and 2b is formed of a Ni-Cr-Al-based alloy. Furthermore, pestle 1,2
The dies used together with the dies, for example, the dies 3 shown in FIG. 3, are preferably formed of a Ni—Cr—Al alloy. At this time, it is also possible to form only the portion constituting the inner wall surface of the die hole 3a with a Ni-Cr-Al-based alloy. The surface roughness of the inner wall surface of the molding portions 1a and 2a of the punches 1 and 2 and the die hole 3a of the die 3 is preferably 1.6 μm or less in Ra.

The Ni applied to the punches 1 and 2 and the die 3 described above
As the Cr-Al alloy, an alloy mainly composed of Ni, Cr and Al, for example, 25 to 60% by weight of Cr,
Is used in the range of 1 to 10% by weight, and the balance is substantially composed of Ni. The Ni-Cr-Al-based alloy may contain a trace amount of unavoidable impurities. In addition, Ni-Cr-Al to which a fourth component or the like described later is positively added.
It is also possible to use a system alloy.

The Ni-Cr-Al alloy used in the present invention preferably contains Ni as a main component. Ni as the main component enhances toughness and imparts corrosion resistance, and is a component that forms the γ phase (mother phase) of the Ni—Cr—Al alloy.

Cr has high corrosion resistance like Ni, and Ni-
Cr-Al based alloy, and punches 1, 2 and dies 3 using it
It is a component that imparts excellent corrosion resistance to the like. In addition, Cr
Is based on the grain boundary reaction,
It is a component that promotes phase precipitation. Ni with appropriate amount of Cr
In a Cr-Al alloy, a Cr-based α phase is precipitated by the aging treatment.

The content of such Cr is preferably in the range of 25 to 60% by weight. If the content of Cr is less than 25% by weight, the amount of the α phase precipitated by the aging treatment is insufficient, and sufficient strength and hardness may not be obtained. On the other hand, Cr
If the content exceeds 60% by weight, the ductility decreases and the material becomes brittle. The content of Cr is preferably in the range of 30 to 45% by weight which allows the α phase to be more stably precipitated,
More preferably, it is in the range of 35 to 43% by weight.

Al is a component that imparts excellent corrosion resistance to the Ni—Cr—Al alloy and the punches 1, 2 and the mortar 3 using the alloy and contributes to the improvement of the strength and the hardness by the combined addition with Cr. is there. That is, Al is a component that precipitates, for example, a γ ′ phase (such as Ni ₃ Al) between the α phase and the γ matrix by aging treatment described later in detail.

Al significantly enhances age hardening when added in a small amount, and its content is preferably in the range of 1 to 10% by weight. If the Al content is less than 1% by weight, the effect of improving hardness and strength by age hardening cannot be sufficiently obtained. On the other hand, if the content of Al exceeds 10% by weight, the hardness after the solution treatment described below becomes too high,
Cutting workability etc. decrease. The content of Al is preferably in the range of 1 to 5% by weight, and more preferably in the range of 1.5 to 4.5% by weight, from which a composite precipitate structure can be obtained more stably.

By obtaining a composite precipitation structure (particularly a laminated structure) of the γ phase, α phase and γ ′ phase as described above,
High hardness and high strength can be imparted to the i-Cr-Al-based alloy and the punches 1, 2 and the dies 3 using the same.
Specifically, Ni-Cr- having the composition as described above
Hardness of the Al-based alloy becomes higher 500Hv of Vickers hardness defined in JIS Z 2244 _-1992 after aging treatment. Further, depending on the control of the aging treatment conditions, etc., the hardness of the Ni—Cr—Al alloy can be set to 680 Hv or more in Vickers hardness.

Ni-Cr-Al having such hardness
The punches 1 and 2 and the mortar 3 for tableting made of a base alloy are used for a tableting machine and the like to be described later, and are used for powders, granules, gels,
It has sufficient strength to press-mold raw materials such as high-viscosity liquids and mixtures thereof. further,
Due to the corrosion resistance based on each component, even when a raw material containing a highly corrosive substance such as an acidic powder is subjected to pressure molding, the corrosion of the mold due to contact with the highly corrosive substance is significantly suppressed. Can be. This means that a decrease in releasability (for example, powder separation) due to corrosion of the mold surface and a decrease in strength are suppressed. Accordingly, it is possible to extend the life of a tablet-forming punch or die having practical strength.

The Ni—Cr—Al alloy used in the present invention is, for example, Mn, Si,
At least one element selected from C and Mg
It may be contained as a deoxidizing agent in the range of not more than% by weight. In particular, it is preferable to contain at least one element selected from Mn, Si and Mg in a range of 0.1% by weight or less.

The punches 1 and 2 and the die 3 are manufactured, for example, as follows. First, a Ni-Cr-Al-based alloy having the above-described composition is melted and cast to form an ingot, and then subjected to hot forging or rolling to obtain a Ni-Cr-Al having an appropriate size and shape. A base alloy material is produced. Melting, casting, forging, rolling and the like are performed according to a conventional method.

Next, the above-mentioned Ni-Cr-Al-based alloy material is subjected to a solution treatment. Heating temperature during solution treatment is 1000
The temperature is preferably in the range of 1350 ° C. Heating temperature is 1000
If the temperature is lower than 0 ° C., the solution-hardened region cannot be reached, and good cutting workability or the like may not be obtained.
On the other hand, if the heating temperature exceeds 1350 ° C., the temperature becomes just below the melting point, and there is a risk of causing partial melting and deformation. The holding time (solution treatment time) at the above-mentioned temperature is not particularly limited, but is preferably 1 hour or more. The rapid cooling from the above temperature is performed by, for example, oil cooling or water cooling.

The solution-treated Ni-Cr-Al-based alloy material is then roughly processed to a shape slightly larger than the required punch or die dimensions. The processing shape at this time is a shape larger by at least 0.2% or more than the required size of the punch or the die, preferably a shape larger by about 1%. At this point, the Ni-Cr-Al-based alloy material has good cutting workability by solution treatment, that is, appropriate hardness, and thus does not cause a decrease in workability or the like. In other words, it can be processed at low cost.

Next, the rough-processed Ni—Cr—Al
Aging treatment is performed on the base alloy material (working material). The heating temperature at the time of the aging treatment is preferably in the range of 500 to 950 ° C. After maintaining at such a temperature for 2 to 6 hours, the temperature is gradually cooled to room temperature. If the heating temperature is less than 500 ° C.,
There is a possibility that the precipitation amount of the phase or the γ 'phase is insufficient, and the age hardening of the Ni—Cr—Al alloy material cannot be sufficiently performed. On the other hand, if the heating temperature exceeds 950 ° C., the temperature becomes close to the solid solution region, the precipitation amount of α phase and γ ′ phase decreases, and the hardness may decrease. The aging temperature is more preferably in the range of 550 to 700 ° C.

By the aging treatment as described above, Ni-
The hardness of the Cr-Al alloy material is Vickers hardness of 500 Hv or more, and further 680 Hv or more. Then, the aging-treated Ni—Cr—Al-based alloy material is finished to a predetermined punch or die size so that the desired punches 1 and 2 can be formed.
And mortar 3 are obtained.

The punches 1 and 2 and the mortar 3 thus obtained
Has high hardness by aging treatment and high strength based on it, and high corrosion resistance based on the composition of the Ni-Cr-Al-based alloy. The punches 1, 2 and the mortar 3 are roughened in advance to approximate dimensions after the solution treatment, and a high-hardness Ni-Cr-Al-based alloy material after the aging treatment is subjected to finishing processing. Since it only needs to be performed, the production cost does not increase. In other words, high hardness at low cost,
High-strength, high-corrosion-resistant tablet punches 1, 2 and dies 3
Can be manufactured.

Next, an example of a tablet forming machine using the tablet forming die set of the present invention will be described. FIG. 4 is a partial cross-sectional view showing the structure of the main part of the tablet molding machine. In the tablet molding machine 10 shown in the figure, the upper punch 1, the lower punch 2, and the die 3 are the same as those described in the above embodiment.

The mortar 3 is provided with a mortar seat 11 so that the mortar hole 3a is located in the vertical direction. The upper punch 1 and the lower punch 2 are respectively connected to an upper punch holding plate 12 and a lower punch holding plate 1.
3 slidably holds in the vertical direction.

The molding part 2a of the lower punch 2 is inserted into the die hole 3a. In this state, the head 2b of the lower punch 2 is
4 is in contact. The forming part 2a of the lower punch 2 and the die hole 3a
The raw material 15 is filled in the container constituted by the above. As the raw material, various powders, granules, gels, high-viscosity liquids, and mixtures thereof are used.

The molding portion 1a of the upper punch 1 is inserted into the die hole 3a filled with the raw material 15. And upper punch 1
By pressing the head 1b through the pressure guide 16, the filled raw material 15 is compressed from above and below to form a tablet. The tablet forming machine 10 has a pressurizing unit (not shown), and a necessary pressure is applied to the pressurizing guide 16.

In this tablet forming machine 10, the upper punch 1,
The mold parts such as the lower punch 2 and the die 3 (at least the molded parts) are made of N having high hardness, high strength and high corrosion resistance as described above.
Because it is made of an i-Cr-Al alloy, even when a raw material containing a highly corrosive substance such as an acidic powder is tableted, corrosion of a punch and a die due to contact with the highly corrosive substance is caused. Progress can be greatly suppressed. Therefore, it is possible to suppress a decrease in releasability (for example, powder detachment) due to corrosion of the surface of the punch and the die, and further a decrease in strength, and it is possible to stably form tablets over a long period of time. Become.
As a result, it is possible to improve the yield of tablet molding and reduce the molding cost.

[0049]

Next, specific examples of the present invention and evaluation results thereof will be described.

Examples 1 to 4 Each alloy sample (Ni-Cr-Al alloy sample) having the composition shown in Table 1 was melted and cast, and then hot forged and hot rolled into a round bar having a diameter of 35 mm. . Each of these Ni-Cr-A
After holding the l-based alloy material at 1200 ° C for 2 hours,
Each was subjected to a solution treatment. Next, each Ni—Cr—Al alloy material after the solution treatment was cut so as to be 1% larger than a predetermined punch (upper punch and lower punch).
The hardness of each Ni-Cr-Al alloy material after the solution treatment is as shown in Table 1.

Next, each of the roughly-worked Ni—Cr—Al-based alloy materials was kept at 650 to 750 ° C. for 5 hours and then air-cooled to room temperature. The hardness of each Ni-Cr-Al alloy material after the aging treatment is as shown in Table 1.

Here, the compositions of Example 1 and Example 2 were changed, and the other conditions were the same. Example 3
In Example 4 and Example 4, the aging treatment temperature was changed with respect to the same composition as Example 2.

Thereafter, finish grinding and polishing were performed up to a predetermined punch size to produce target punches.
In addition, the upper punch and the lower punch were made of the Ni-Cr-Al-based alloy of each composition. The pair of upper and lower punches thus obtained was subjected to the characteristic evaluation described later.

Comparative Example 1 Using a conventional alloy tool steel (SKS2), upper punches and lower punches having the same shapes as those of the above-mentioned examples were prepared and subjected to the characteristic evaluation described later.

Comparative Example 2 A conventional alloy tool steel (SKS2) was plated with chromium.
Upper punches and lower punches having the same shape as those of the above-mentioned examples were produced, and were subjected to characteristic evaluation described later.

[0056]

[Table 1]

The above Examples 1 to 4 and Comparative Examples 1 to 2
And a pair of upper and lower punches were assembled in the tablet molding machine shown in FIG. 4 to perform pressure molding of the acidic powder. The dies used were made of alloy tool steel. The acidic powder used as the raw material powder is a strongly acidic powder that exhibits pH2 when dissolved in water. Under such conditions, the corrosion resistance and the releasability were confirmed.

The corrosion resistance of each of Example 1, Example 2 and Comparative Example 1 was visually checked for corrosion under the conditions of (1) holding at 75% humidity for 3 days, and (2) holding water droplets for 1 day. Observed. Table 2 shows the results.

[0059]

[Table 2]

Regarding the releasability, each punch was incorporated into a tablet forming machine, and it was confirmed whether or not powder adhered to the punch when the tablets were continuously formed. Example 1, Example 2, and Comparative Example 2
For (1) initial (after 0 minutes), (2) after 15 minutes, and (3) after 30 minutes, the presence or absence of powder adhesion was visually observed. Table 3 shows the results.

[0061]

[Table 3]

As is clear from Tables 2 and 3, the conventional alloy tool steel used as a comparative example was completely corroded in high humidity and had insufficient corrosion resistance. In Examples 1 and 2, no corrosion occurred. Further, even under severe conditions of contact with water droplets, no corrosion was observed, and good corrosion resistance was confirmed.

In the case of alloy tool steel, powder adhesion was observed immediately after tablet molding, and it was impossible to continue molding after 30 minutes. However, in Examples 1 and 2 according to the present invention,
Even after 30 minutes from the start of tablet molding, no powder adhesion was observed at all, and it was confirmed that the tablet had good release properties. In addition, the same effect was recognized for the dies manufactured using the same alloys as those in the above examples.

[0064]

As described above, the punch and die for tableting of the present invention have extremely high hardness and are particularly suitable for molding raw materials containing corrosive substances such as acidic substances. Has excellent corrosion resistance. When a tablet is formed by a tablet forming machine using a punch and a die, the releasability is extremely good, and the tablet can be stably formed over a long period of time.

Furthermore, according to the method for manufacturing a punch and a die for tablet forming of the present invention, although the punch and the die have high hardness, they are in a state of having a hardness that facilitates processing after a solution treatment in a manufacturing process. At this stage, since it can be processed into a desired shape with high precision, the formability of the punch and the die can be improved.

[Brief description of the drawings]

FIG. 1 is a plan view showing an upper punch as one embodiment of a tablet forming punch of the present invention.

FIG. 2 is a plan view showing a lower punch as another embodiment of the tablet forming punch of the present invention.

FIG. 3 is a cross-sectional view showing one embodiment of a tablet forming die of the present invention.

FIG. 4 is a partial cross-sectional view showing a main structure of a configuration example of a tablet forming machine using a tablet forming punch and a die according to the present invention.

[Explanation of symbols]

 DESCRIPTION OF SYMBOLS 1 ... Upper punch 1a, 2a ... Molding part 2 ... Lower punch 3 ... Mold 3a ... Mold hole (through hole) 10 ... Tablet molding machine

Continued on the front page (72) Inventor Junji Taniguchi 8 Shinsugita-cho, Isogo-ku, Yokohama-shi, Kanagawa Prefecture Inside the Toshiba Yokohama Office (72) Inventor Hideo Koizumi 8 Shinsugita-cho, Isogo-ku, Yokohama-shi, Kanagawa Prefecture Toshiba Yokohama Co., Ltd. In-house (72) Inventor Hikaru Fukuyama 5-1-1, Mayoka, Ikeda-shi, Osaka Takeda Pharmaceutical Mayoka-ryo (72) Inventor Koji 2-1-16-1, Miwa-cho, Toyonaka-shi, Osaka (72 ) Inventor Tetsuro Tabata 2-9-1 A-413 Yamada Nishi, Suita-shi, Osaka (72) Inventor Etsuharu Nakamura 1-2-201, Kitaeguchi, Higashi-Yodogawa-ku, Osaka-shi F-term (reference) 4K018 CA16 KA58

Claims (20)

[Claims] 1. A punch used for tablet molding of a raw material containing at least one selected from powders, granules, gels, and high-viscosity liquids, wherein at least a molding part in contact with said raw material is Ni-based. A tablet-forming punch made of a Cr-Al-based alloy. 2. The punch for tablet molding according to claim 1, wherein the Ni—Cr—Al alloy contains 25 to 60% by weight of Cr;
Al in the range of 1 to 10% by weight, with the balance being substantially Ni
A tablet-forming punch comprising: 3. The tablet-forming punch according to claim 2, wherein the Ni—Cr—Al-based alloy further comprises Mn, Si, C
And at least one element selected from Mg and Mg in a range of 0.1% by weight or less. 4. The punch for tablet molding according to claim 2, wherein the Ni-Cr-Al-based alloy further contains 0.1% by weight of at least one element selected from Mn, Si and Mg.
A tablet forming punch comprising the following range. 5. The tablet forming punch according to claim 1, wherein the Ni—Cr—Al alloy has a Vickers hardness of 500.
A tablet forming punch having a hardness of Hv or more. 6. The punch for tablet forming according to claim 1, wherein the punch is used for pressure-forming a corrosive substance as the raw material. 7. The punch for tablet forming according to claim 1, wherein the surface roughness of said forming portion is 1.6 μm or less in Ra. 8. A mill used for tablet molding of a raw material containing at least one selected from powders, granules, gels, and high-viscosity liquids, wherein at least a molding part in contact with said raw material is Ni-based. A tablet-forming die comprising a Cr-Al-based alloy. 9. The tablet molding die according to claim 8, wherein the Ni-Cr-Al-based alloy contains 25 to 60% by weight of Cr,
Al in the range of 1 to 10% by weight, with the balance being substantially Ni
A tablet-forming mortar comprising: 10. The tablet molding die according to claim 9, wherein the Ni—Cr—Al-based alloy further comprises Mn, Si, and C.
And at least one element selected from Mg and Mg in a range of 0.1% by weight or less. 11. The tablet-forming die according to claim 9, wherein the Ni—Cr—Al-based alloy further contains 0.1% by weight of at least one element selected from Mn, Si, and Mg.
A mill for tablet molding characterized by containing the following range. 12. The tablet molding die according to claim 8, wherein the Ni—Cr—Al alloy has a Vickers hardness of 500.
A tablet molding die having a hardness of Hv or more. 13. The tablet molding die according to any one of claims 8 to 12, wherein the raw material is used for pressure molding of a corrosive substance. 14. The tablet molding die according to claim 8, wherein the surface roughness of the molding portion is 1.6 μm or less in Ra. 15. In producing a punch used for tablet molding of a raw material containing at least one selected from powders, granules, gels, and high-viscosity liquids, a Ni—Cr—Al-based alloy material is solution-processed. Treating, and at least the molded part in contact with the raw material is the Ni-
A step of roughly processing the solution-treated Ni-Cr-Al-based alloy material to a shape larger than a predetermined punch size so that the Ni-Cr-Al-based alloy material is made of a Cr-Al-based alloy; And a step of finishing the aging-treated Ni-Cr-Al-based alloy material to the predetermined punch size. 16. The method for manufacturing a tablet forming punch according to claim 15, wherein in the solution treatment step, the Ni-Cr-Al-based alloy material is heated at a temperature in a range of 1000 to 1350 ° C. A method for producing a tablet-forming punch characterized by cooling with water or oil. 17. The method for producing a punch for tablet molding according to claim 15, wherein the aging treatment step includes the step of:
A method for producing a punch for tablet molding, comprising performing heat treatment at a temperature in the range of 500 to 950 ° C. 18. A method for producing a mill used for tablet molding of a raw material containing at least one selected from powders, granules, gels, and high-viscosity liquids, wherein a Ni—Cr—Al-based alloy material is solution-processed. Treating, and at least the molded part in contact with the raw material is the Ni-
A step of rough-working the solution-treated Ni-Cr-Al-based alloy material to a shape larger than a predetermined die size so that the Ni-Cr-Al-based alloy material is made of a Cr-Al-based alloy; A process of subjecting the aging-treated Ni-Cr-Al-based alloy material to the predetermined die size. 19. The method for manufacturing a tablet forming die according to claim 18, wherein, in the solution treatment step, the Ni-Cr-Al-based alloy material is heat-treated at a temperature in a range of 1000 to 1350 ° C. A method for producing a tablet-forming die, comprising cooling with water or oil. 20. The method for manufacturing a die for tablet molding according to claim 18 or 19, wherein the aging treatment step comprises the step of:
A method for producing a die for tablet molding, comprising heat-treating at a temperature in the range of 500 to 950 ° C.