JP2001010904A - Disinfectant for oral care good - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain a disinfectant removing bacteria and suppressing mold generation and bacteria propagation in any handling of oral care goods e.g. toothbrush or even under any unsanitariness. SOLUTION: This disinfectant for oral sanitary goods comprises 30-100 wt.% ethanol solution containing at least a disinfectant e.g. cetylpyridinium chloride.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to an oral hygiene tool, and more particularly to a disinfectant for keeping sanitary tools such as a toothbrush, a toothpick, and a storage device for cleaning the oral cavity clean.

[0002]

2. Description of the Related Art Toothbrushes are required to be clean because they are used in the oral cavity. However, at present, ordinary households store and use toothbrushes without special sterilization treatment. For example, a toothbrush after use is stored in a wash cabinet or a portable case with a bristle bundle being moist during a use period, so that the toothbrush is insufficiently dried and mold and bacteria easily propagate. This is unsanitary for daily oral use. In particular, the vicinity of the root of the toothbrush with poor air permeability is considerably dirty. In addition, insufficient washing of the toothbrush, and leftover food residue and dentifrice, further promotes the growth of mold and bacteria. In addition, the place of use is in an environment where the humidity is very high and mold is easily generated and bacteria are easily propagated. Originally, this oral hygiene tool such as a toothbrush should be cleaned with hot water, but it is hardly used at present. Recently, an antibacterial toothbrush has been proposed as a method for suppressing the growth of various bacteria during storage.

[0003]

The use of hot water involves the trouble of boiling the water, particularly the risk of burns and the like due to the carelessness of infants. In addition, the use of antibacterial toothbrushes has no permanent effect, and the antibacterial effect decreases as the number of uses increases. Thus, the handling of sanitary tools such as toothbrushes largely depends on self-management. At present, no simple method has been found for anyone to reliably manage sanitation. The present invention has been made in view of the above, and has been made in any manner in which a sanitary tool such as a toothbrush is handled, or in any unsanitary situation, removes bacteria and removes mold. It is an object of the present invention to provide a disinfectant that suppresses the generation and propagation of bacteria.

[0004]

Means for Solving the Problems In order to achieve the above object, the present inventors have found a means for keeping a toothbrush and a mouthwashing device clean by a simple method, and have completed the present invention. That is, one or more of the main components are ethanol.
It is a disinfectant that is used by a simple means such as spraying, dipping, etc., on a toothbrush or the like in an aqueous solution containing at least one or more kinds of disinfectants. The invention according to claim 1 is a disinfectant for an oral hygiene tool comprising a 30 to 100% ethyl alcohol solution containing at least a disinfectant. The invention according to claim 2 is characterized in that the disinfectant is cetylpyridinium chloride, chlorhexidine, benzethonium chloride, decalinium chloride, grapefruit seed extract, polylysine, egg white lysozyme, glycerin fatty acid ester, tea extract, protamine, bamboo extract A disinfectant for an oral hygiene device according to claim 1, wherein the disinfectant contains at least one or more selected from the group consisting of a cinnamon extract, a sagebrush extract, a hinoki thiol, a sagebrush extract, a forsythia extract, and a pectin degradation product. is there.

[0005] Further, the invention according to claim 3 is a disinfectant according to claim 1 or 2, wherein a fragrance having a fragrance component having a disinfecting property is blended. Further, the invention according to claim 4 is the disinfectant according to claim 1 or 2, wherein the oral hygiene implement is a toothbrush.

Oral hygiene appliances such as toothbrushes have a high transpiration that promotes drying and an effect of suppressing the growth of various germs in order to solve both the difficulty of drying and the breeding of germs associated with the hygiene problem. is necessary. In addition, as long as the device is used in the oral cavity, its safety must be sufficiently confirmed. Methanol, isopropyl alcohol, and the like can be considered as the highly transpirable solvent, but there is a problem in use in view of safety and odor during use. In that regard, ethanol is most suitable as a solvent having both a high transpiration property and a stronger effect. But,
Ethanol has a strong disinfecting effect, but has a problem of lack of sustainability because it evaporates. Therefore, a disinfectant was added for the purpose of maintaining the efficacy. The fungicide to be added needs to be confirmed to be safe. In addition, it is required that there be no problem with odor and taste. As a disinfectant satisfying these conditions, a disinfectant such as cetylpyridinium chloride and a disinfectant used as a food additive were added. By combining these disinfectants and ethanol, a disinfectant for oral hygiene appliances having both immediate effect and sustainability was obtained.

[0007]

BEST MODE FOR CARRYING OUT THE INVENTION The present inventor has proposed that an aqueous solution containing ethyl alcohol as a main component or an ethyl alcohol and a disinfectant as a main component is sprayed or dipped into a sanitary tool such as a toothbrush. In addition, it was found that sterilization of attached bacteria, suppression of mold generation and storage of bacteria during storage were suppressed.

That is, ethyl alcohol or an aqueous solution containing ethyl alcohol sterilizes bacteria attached to a toothbrush or the like in a short time. In addition, since ethyl alcohol or an aqueous solution containing ethyl alcohol has a high permeability, it reaches the root of the toothbrush hair bundle, is completely sterilized and washed, and is easier to dry than an aqueous solution. But difficult to breed. Furthermore, by blending another disinfectant in ethyl alcohol, the applicable bacterial species can be expanded and the bactericidal effect can be maintained for a long time.

As the alcohol of the present invention, ethyl alcohol is a main component, but isopropyl alcohol or the like can be used depending on sanitary utensils. However, those frequently used in a short cycle, such as a toothbrush, are of course not only safe but also desirably free from odor, skin irritation and the like. The concentration of ethyl alcohol is in the range of 30 to 100% by weight. Considering the bactericidal effect of the toothbrush, 30-80% by weight is desirable,
To accelerate drying, the higher the concentration, the better. Meanwhile, 3
If it is less than 0% by weight, it cannot be sterilized in a short time. Also, the drying power is weakened, which is not appropriate.

The disinfectant of the present invention has a bactericidal activity,
There is no particular limitation as long as it is soluble in water and / or alcohol, but it is for humans and edible, and its safety has been confirmed, and it has been confirmed as a food additive and the like. It is desirable to use Specifically, examples of chemically synthesized products include cetylpyridinium chloride, chlorhexidine salt, benzethonium chloride, isopropylmethylphenol (IPMP), and triclosan. In addition, as a food additive, grapefruit seed extract, polylysine, egg white lysozyme, glycerin fatty acid ester, tea extract, protamine, bamboo extract, sesame extract, sagebrush extract, hinokitiol, honoki extract, forsythia extract, pectin decomposition Things. In the sense that the disinfectant has a feeling of use,
Flavors can be added to increase commercial value. In addition, when a fragrance composed of a fragrance component having a sterilizing effect is used as a fragrance to be blended, the bactericidal performance can be further improved. As the fragrance component having a disinfecting property, citronellal, 1-menthol, thymol, phenol, eugenol, geraniol, α-terpineol, citronellol, citral, cinamic aldehyde, p-cresol, cineol, jasmine oil, rose oil, cedarwood oil And clove oil. The mixing ratio of the disinfectant is in the range of 0.001 to 1% by weight based on the solution. Considering the persistence of the bactericidal effect, 0.005% by weight or more is preferable. Also,
It is effective to add two or more types of disinfectants having different germicidal action mechanisms or germicidal spectra. For example, grapefruit seed extract is effective at low concentrations against Staphylococcus aureus, but not at the same concentration against other bacteria. Cetylpyridinium chloride, on the other hand, is relatively ineffective against Staphylococcus aureus. It is effective to add two or more bactericides to make them mutually complement.

The disinfectant may be selected and used according to the purpose of use and the scene of use, and may be used as a mixture of a chemically synthesized product and a food additive.

The above-mentioned solution is effective against bacteria which exist in a normal environment such as Staphylococcus aureus, Pseudomonas aeruginosa and Escherichia coli. In addition, oral streptococci (St), which are the causative bacteria of caries,
It is also effective against S. reptococcus mutans. Therefore, in addition to a toothbrush, it can be used for oral hygiene appliances such as a toothpick, an interdental brush, a floss and a pick. The disinfectant of the present invention can be used by dipping as a liquid, containing and spraying in a spray container, or by containing and spraying in a pressure-resistant container together with a propellant.

The disinfectant of the present invention may contain any conventionally known optional components as long as the effects of the present invention are not impaired. Such ingredients include fragrances (mint, citrus, citrus, etc.) detergents (anionic, cationic, nonionic, amphoteric surfactants and solvents such as PEG and propylene glycol) Modifiers (glycerin, PEG, propylene glycol, etc.) Gelling agents (gum such as xanthan gum, tamarind gum) Deodorants (plant extracts such as tea extract, bamboo extract, copper chlorophyll) and the like.

[0014]

EXAMPLES The present invention will be described in more detail with reference to the following examples, but the present invention is not limited to these examples.

Test Example 1 A stock solution was prepared by mixing and dissolving 30 parts of ethanol, 0.001 part of cetylpyridinium chloride, 0.001 part of grapefruit seed extract, and 100 parts of perfume to make up 100 parts of water. Table 1 shows the results of contacting various bacteria with the prepared liquid and confirming the change in the number of bacteria. Table 1 Changes in the number of bacteria (live bacteria rate)

[0016]

[Table 1]

As shown in Table 1, no viable bacteria were observed 30 seconds after contact with the prepared solution.

Test Example 2 An undiluted solution was prepared by mixing and dissolving 30 parts of ethanol, 0.001 part of cetylpyridinium chloride, 0.001 part of a grapefruit seed extract, and a trace amount of a fragrance to 100 parts of water. . A used toothbrush was prepared, half of which was not sprayed with the adjusted solution, half was sprayed, dried and then washed with sterile water. Table 2 shows the results of measurement of the bacteria in the washed sterilized water. Table 2 Number of bacteria on toothbrush with and without spraying

[0019]

[Table 2]

As shown in Table 2, unprocessed 140
While the number of bacteria was confirmed to be 0 to 790000 cells / cell, only 11 to 380 cells / cell could be confirmed in the treated section. The sterilization effect by spraying was confirmed.

<Test Example-3> 30 to 80 parts of ethanol,
A stock solution was prepared by mixing and dissolving 0.001 part of cetylpyridinium chloride, 0.001 part of a grapefruit seed extract and a trace amount of a fragrance so as to become 100 parts of water. The residual water ratio on the toothbrush was checked when the prepared liquid was sprayed on the toothbrush and when water was sprayed (assuming only washing with water).
The results are shown in FIG. As shown in FIG. 1, it takes more than 3 hours for the toothbrush to dry only by washing with water. However, the drying time can be reduced by using a disinfecting solution to which ethanol has been added.

<Test Example 4> 30 parts of ethanol, cetylpyridinium chloride, grapefruit seed extract, and a trace amount of perfume were mixed in a combination as shown in Table 3 and adjusted to 100 parts with water. The total amount of cetylpyridinium chloride and grapefruit seed extract added was 0.01 parts by weight. The prepared solution was brought into contact with various bacterial solutions to check for the presence of viable bacteria. Table 3 Presence or absence of live bacteria

[0023]

[Table 3]

Mixing ratio Cetylpyridinium chloride: Grapefruit seed extract As described above, the addition of a disinfectant having a different effect makes it more effective against a wider range of bacteria.

[Brief description of the drawings]

FIG. 1 is a graph showing the residual water content (%) in a toothbrush.

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Claims (4)

[Claims] 1. An antibacterial agent containing at least 30 to 10
A disinfectant for oral hygiene tools consisting of a 0% ethyl alcohol solution. 2. The disinfectant is cetylpyridinium chloride, chlorhexidine, benzethonium chloride, decalinium chloride, isopropylmethylphenol, triclosan, grapefruit seed extract, polylysine, egg white lysozyme, glycerin fatty acid ester, tea extract, protamine, bamboo 2. The disinfectant for an oral hygiene device according to claim 1, wherein the disinfectant contains at least one selected from an extract, a cinnamon extract, a sagebrush extract, a hinokitiol, a fennel extract, a forsythia extract, and a pectin degradation product. . 3. A disinfectant according to claim 1, wherein a fragrance having a bactericidal fragrance component is blended. 4. The disinfectant according to claim 1, wherein the oral hygiene implement is a toothbrush.