JP2000350783A - Injection method and apparatus of radioactive liquid - Google Patents

Injection method and apparatus of radioactive liquid

Info

Publication number
JP2000350783A
JP2000350783A JP11166230A JP16623099A JP2000350783A JP 2000350783 A JP2000350783 A JP 2000350783A JP 11166230 A JP11166230 A JP 11166230A JP 16623099 A JP16623099 A JP 16623099A JP 2000350783 A JP2000350783 A JP 2000350783A
Authority
JP
Japan
Prior art keywords
liquid
radioactive liquid
injecting
medicine
injection
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP11166230A
Other languages
Japanese (ja)
Inventor
Akira Tanaka
明 田中
Motohito Sasaki
基仁 佐々木
Takafumi Suzuki
啓文 鈴木
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Heavy Industries Ltd
Original Assignee
Sumitomo Heavy Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Heavy Industries Ltd filed Critical Sumitomo Heavy Industries Ltd
Priority to JP11166230A priority Critical patent/JP2000350783A/en
Publication of JP2000350783A publication Critical patent/JP2000350783A/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/1407—Infusion of two or more substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/007—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests for contrast media
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/1785—Syringes comprising radioactive shield means

Abstract

PROBLEM TO BE SOLVED: To reduce exposure quantity to a handling person and measure the dose simply and accurately by temporarily keeping the whole radioactive liquid in a radiation shielding liquid retainer immediately before injection, measuring the radiation dose, then injecting the whole quantity into a human body. SOLUTION: A medicine liquid of a precalculated quantity is pushed in a medicine retainer 30 by lightly pushing a medicine injecting cylinder 26. And, the medicine liquid remaining in a valve 16 and the inlet of a coil-form medicine retainer 30 is pushed in the medicine retainer 30 by quantitative discharge of distilled water for injection or saline by a pushing cylinder 22. Thereby the whole quantity is pushed in the retainer 30. Then, inspection preparation is arranged by attaching an injection needle 20 at the tip of a tube 12 to a subject, and the radiation dose is measured by a radioactivity measuring instrument 32. Then the total radioactive medicine is administered to the subject by feeding distilled water for injection or saline with the pushing cylinder 22. Thus accurate administration is possible with reduced exposure quantity to a handling person.

Description

【発明の詳細な説明】DETAILED DESCRIPTION OF THE INVENTION

【０００１】[0001]

【発明の属する技術分野】本発明は、放射性液体の注入
方法及び装置に係り、特に、半減期の短い、放射性の強
い核種で標識された放射性医薬品を被験者に投与する際
に用いるのに好適な、放射性液体を人体に注入するため
の放射性液体の注入方法及び装置に関する。BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a method and an apparatus for injecting a radioactive liquid, and more particularly to a radiopharmaceutical labeled with a highly radioactive nuclide having a short half-life and suitable for use in administering to a subject. The present invention relates to a method and an apparatus for injecting a radioactive liquid for injecting a radioactive liquid into a human body.

【０００２】[0002]

【従来の技術】病院の検査室等において、半減期が短
い、放射性の強い核種で標識された放射性医薬品を被験
者に投与する場合、取扱者の放射線被爆を防止すると共
に、所定の投与量を、正確に、一定速度で投与する機構
が必要となり、自動化・遠隔化装置が必要である。その
ため、被験者に放射線医薬品を自動投与する装置とし
て、ＭＲ造影剤注入装置や放射性医薬品自動注入装置等
が実用化されている。2. Description of the Related Art When a radiopharmaceutical labeled with a highly radionuclide with a short half-life is administered to a subject in a laboratory or the like of a hospital, it is necessary to prevent the operator from being exposed to radiation and to set a predetermined dose. A mechanism for precisely administering the drug at a constant rate is required, and an automatic and remote control device is required. Therefore, as a device for automatically administering a radiopharmaceutical to a subject, an MR contrast agent injection device, a radiopharmaceutical automatic injection device, and the like have been put to practical use.

【０００３】これらの注入装置は、基本的に、薬液を一
定量充填されたシリンジと、被験者までのチューブ、該
チューブを注射用蒸留水又は生理食塩水で充填したり、
薬液全量を投与するための最後の押し込み注入用のシリ
ンジ、及び、液流れを切り換えるための自動又は手動バ
ルブ、一定速度で投与するための動作機構、コントロー
ラ等から構成されている。[0003] These injection devices basically include a syringe filled with a certain amount of a drug solution, a tube up to a subject, and filling the tube with distilled water for injection or physiological saline.
It consists of a syringe for the final push-in injection for administering the whole amount of the drug solution, an automatic or manual valve for switching the liquid flow, an operation mechanism for administering at a constant speed, a controller, and the like.

【０００４】このような注入装置を用いて、短寿命核種
（例えば、ポジトロン放出核種として、15Ｏは２分、11
Ｃは２０分、18Ｆは１１０分の半減期を持つ）で標識さ
れた15Ｏ−水あるいは11Ｃ−メチオニンあるいは18Ｆ−
ＦＤＧ（フルオロデオキシグルコース）等の薬剤を被験
者に投与する場合、従来は、、投与前に、薬剤をシリン
ジに入れた状態で放射能量を測定し、投与後、再度シリ
ンジ内に残留した放射能量を測定し、投与した時間（基
準時間）での放射能量を放射能減衰補正して求めること
で、被験者に投与された放射能量を測定していた。[0004] Using such an implanter, short-lived nuclides (for example, as a positron-emitting nuclide, 150 O is 2 minutes, 11
C has a half-life of 20 minutes and 18F has a half-life of 110 minutes.) 15 O-water or 11 C-methionine or 18 F-
Conventionally, when a drug such as FDG (fluorodeoxyglucose) is administered to a subject, the radioactivity is measured with the drug in a syringe before administration, and the radioactivity remaining in the syringe is again measured after the administration. The amount of radioactivity administered to the subject was measured by determining the amount of radioactivity at the time of measurement and administration (reference time) by correcting for radioactivity decay.

【０００５】通常、薬液のバイアルは、濃度が既知であ
り、希望する放射能量を得るには、計算で求めた、決め
られた容量を吸引することになる。この場合、バイアル
でなくても、別装置から一定量の薬液を注入することも
可能である。いずれにしても、一定量吸入したシリンジ
は、正確に測定する必要があるため、通常、鉛容器に入
れた状態からシリンジを取出し、測定後、再度鉛容器に
入れて、検査室被験者の場所に運搬し、装置に取り付
け、投与終了後、シリンジに残留する放射能量を再度測
定して、投与量を求めていた。Usually, the concentration of a vial of a drug solution is known, and in order to obtain a desired amount of radioactivity, a predetermined volume calculated and calculated is aspirated. In this case, it is also possible to inject a certain amount of a chemical solution from another device without using a vial. In any case, it is necessary to accurately measure the syringe that has been inhaled in a certain amount. It was transported, attached to the device, and after administration was completed, the amount of radioactivity remaining in the syringe was measured again to determine the dose.

【０００６】[0006]

【発明が解決しようとする課題】従って、投与前と投与
後の２回、放射能量を正確に測定する必要があり、手間
がかかって面倒であるだけでなく、シリンジに含まれる
放射能量を測定するときに、測定者は被爆されることに
なる。しかも、投与後にシリンジを測定することで、被
爆し、投与液が身体に付着する危険もあった。Therefore, it is necessary to accurately measure the amount of radioactivity twice before and after administration, which is not only troublesome and troublesome, but also involves measuring the amount of radioactivity contained in a syringe. When doing so, the measurer will be exposed. Moreover, by measuring the syringe after administration, there is also a danger of being exposed and causing the administration solution to adhere to the body.

【０００７】本発明は、前記従来の問題点を解決するべ
くなされたもので、短寿命核種で標識された放射性医薬
品や放射性化合物の投与量を、取扱者の放射線被爆量を
減少させて、簡単且つ正確に測定することを課題とす
る。SUMMARY OF THE INVENTION The present invention has been made to solve the above-mentioned conventional problems, and can reduce the dose of radiopharmaceuticals and radioactive compounds labeled with short-lived nuclides by reducing the radiation exposure of the operator. Another object is to measure accurately.

【０００８】[0008]

【課題を解決するための手段】本発明は、放射性液体を
人体に注入するための放射性液体の注入方法において、
注入直前に、放射性液体の全量を一時的に、放射線遮蔽
された液体保持部に収容し、該液体保持部に収容された
放射性液体の放射能量を測定した後、該放射性液体の全
量を人体に注入するようにして、前記課題を解決したも
のである。According to the present invention, there is provided a method for injecting a radioactive liquid for injecting a radioactive liquid into a human body, comprising the steps of:
Immediately before injection, the entire amount of the radioactive liquid is temporarily stored in the radiation-shielded liquid holding unit, and the radioactivity of the radioactive liquid stored in the liquid holding unit is measured. This problem has been solved by injecting.

【０００９】本発明は、又、放射性液体を人体に注入す
るための放射性液体の注入装置において、注入直前の放
射性液体の全量を一時的に収容可能な液体保持部と、該
液体保持部を遮蔽する放射線遮蔽手段と、該液体保持部
に収容された放射性液体の放射能量を測定する放射能測
定手段と、放射能測定後の放射性液体の全量を人体に注
入するための液体押し込み手段とを備えることにより、
前記課題を解決したものである。According to the present invention, in a radioactive liquid injection device for injecting a radioactive liquid into a human body, a liquid holding portion capable of temporarily storing the entire amount of the radioactive liquid immediately before injection is provided, and the liquid holding portion is shielded. Radiation shielding means, radioactivity measuring means for measuring the radioactivity amount of the radioactive liquid contained in the liquid holding part, and liquid pushing means for injecting the whole radioactive liquid after the radioactivity measurement into a human body. By doing
This has solved the above-mentioned problem.

【００１０】更に、前記液体保持部に放射性液体を送入
するための放射性液体送入手段を遮蔽する放射線遮蔽手
段を備えたものである。Further, there is provided a radiation shielding means for shielding a radioactive liquid feeding means for feeding a radioactive liquid into the liquid holding portion.

【００１１】又、前記手段を、全て、移動可能な台車に
搭載したものである。Further, all of the means are mounted on a movable cart.

【００１２】[0012]

【発明の実施の形態】以下図面を参照して、本発明の実
施形態を詳細に説明する。Embodiments of the present invention will be described below in detail with reference to the drawings.

【００１３】本発明の基本的な構成に対応する第１実施
形態を図１に示す。FIG. 1 shows a first embodiment corresponding to the basic configuration of the present invention.

【００１４】本実施形態は、生理食塩水又は注射用蒸留
水が入れられたバック１０と、後端に該バック１０が接
続され、途中に、バック１０側から順に、２個の三方活
栓付バルブ１４、１６とフィルタ１８が配設され、先端
に注射針２０が接続されたチューブ１２と、前記三方活
栓付バルブ１４を介して、該チューブ１２内の生理食塩
水又は注射用蒸留水を押し込むための、例えば超音波モ
ータによるサーボアクチュエータ２４付の押し込み用シ
リンジ２２と、前記三方活栓付バルブ１６を介して、前
記チューブ１２内に放射性薬剤を注入するための、例え
ば鉛製のシールド容器２８内に収容された、例えば超音
波モータによるサーボアクチュエータ付又は手動の放射
性薬剤注入用シリンジ２６とを備えた注入装置におい
て、前記薬剤注入用シリンジ２６とフィルタ１８の間
に、注入直前の放射性薬剤の全量を一時的に収容可能
な、例えばコイル状の薬剤保持部３０と、該薬剤保持部
３０に収容された放射性薬剤の放射能量を測定するため
の、表示部３４を有する放射能測定器３２を設け、該放
射能測定器３２により薬剤保持部３０に収容された放射
性薬剤の放射能を測定した後、該放射性薬剤の全量を、
前記押し込み用シリンジ２２により被験者に注入するよ
うにしたものである。In this embodiment, a bag 10 containing physiological saline or distilled water for injection is connected to the bag 10 at the rear end, and two valves with a three-way stopcock are arranged in the middle from the bag 10 side. 14 and 16 and a filter 18 are disposed, and the saline 12 or the distilled water for injection is pushed into the tube 12 through the tube 12 to which the injection needle 20 is connected at the tip and the valve 14 with the three-way cock. For example, through a push-in syringe 22 with a servo actuator 24 by an ultrasonic motor and a valve 16 with a three-way cock, for injecting a radiopharmaceutical into the tube 12, for example, in a shield container 28 made of lead. The contained injection device, for example, provided with a servo actuator with an ultrasonic motor or a syringe 26 for manually injecting a radioactive drug, Between the syringe 26 and the filter 18, for example, a coil-shaped medicine holding part 30 capable of temporarily containing the whole amount of the radiopharmaceutical just before injection, and measuring the radioactivity of the radiopharmaceutical contained in the medicine holding part 30 In order to measure the radioactivity of the radiopharmaceutical stored in the drug holding unit 30 by providing a radioactivity measuring device 32 having a display unit 34, the total amount of the radiopharmaceutical,
The injection syringe 22 is used to inject into the subject.

【００１５】前記薬剤注入用シリンジ２６は、先端（図
では下端）が開放されているシールド容器２８に格納さ
れ、該シールド容器２８内に収容されたままの状態で、
装置に着脱可能とされている。この薬剤注入用シリンジ
２６内の薬液は、バルブ１６の切換えによって、自動又
は手動で、全量がチューブ１２内に押し込まれ、チュー
ブ１２の途中に設けられたコイル状の薬剤保持部３０に
向けて全量が投入される。更に、バルブ１６とコイル状
の薬剤保持部３０の入口に残る薬液は、押し込み用シリ
ンジ２２で注射用蒸留水又は生理食塩水を定められた量
吐出して、薬液全量を薬剤保持部３０に押し込む。The syringe 26 for drug injection is stored in a shield container 28 whose tip (lower end in the figure) is open, and is stored in the shield container 28.
It is detachable from the device. The entire amount of the drug solution in the drug injection syringe 26 is automatically or manually pushed into the tube 12 by switching the valve 16, and the entire amount of the drug solution is directed toward the coil-shaped drug holding unit 30 provided in the middle of the tube 12. Is input. Further, the drug solution remaining at the inlet of the valve 16 and the coil-shaped drug holding unit 30 discharges a predetermined amount of distilled water for injection or physiological saline with the pushing syringe 22, and pushes the whole drug solution into the drug holding unit 30. .

【００１６】前記薬剤保持部３０は、前記薬剤注入用シ
リンダ２６により薬液の全量が投入された状態で、薬液
が被験者に到達しないコイル容量を確保しておく。The medicine holding section 30 secures a coil capacity such that the medicine does not reach the subject when the entire amount of the medicine is charged by the medicine injection cylinder 26.

【００１７】前記放射能測定器３２としては、正確に測
定するためには、ウェル型ドーズ（放射線量）キャリブ
レータが好適である。しかしながら、目的によっては、
ＮａＩシンチレーション検出器、あるいは、ＧＭ検出器
等、簡易検出器を用いて、値をレートメータや放射線カ
ウンタ等で検出する方法も有効である。As the radioactivity measuring device 32, a well-type dose (radiation dose) calibrator is suitable for accurate measurement. However, for some purposes,
It is also effective to use a simple detector such as a NaI scintillation detector or a GM detector to detect the value with a rate meter, a radiation counter, or the like.

【００１８】以下、本実施形態の作用を説明する。Hereinafter, the operation of the present embodiment will be described.

【００１９】装置に取り付けた後、薬剤注入用シリンジ
２６を軽く押し込み、予め計算された量を吐出して、薬
液全量を薬剤保持部３０に押し込む。更に、バルブ１６
とコイル状の薬剤保持部３０の入口に残る薬液は、押し
込み用シリンジ２２で注射用蒸留水又は生理食塩水を定
められた量吐出して、薬液全量を薬剤保持部３０に押し
込む。After the device is attached to the apparatus, the syringe 26 for drug injection is lightly pushed in, a predetermined amount is discharged, and the whole amount of the drug solution is pushed into the drug holding section 30. Further, the valve 16
The drug solution remaining at the entrance of the coil-shaped drug holding unit 30 discharges a predetermined amount of distilled water for injection or physiological saline with the pushing syringe 22, and pushes the entire drug solution into the drug holding unit 30.

【００２０】次に、被験者にチューブ１２先端の注射針
２０を取り付ける。Next, the injection needle 20 at the tip of the tube 12 is attached to the subject.

【００２１】検査準備が整ってから、放射能測定器３２
で正確な放射能量を測定し、押し込み用シリンジ２２
で、注射用蒸留水又は生理食塩水を流して、薬剤保持部
３０に保持されていた放射性薬剤の全量を被験者に投与
する。After preparation for inspection, the radioactivity measuring device 32
The accurate amount of radioactivity is measured with a syringe 22
Then, distilled water for injection or physiological saline is flowed, and the entire amount of the radiopharmaceutical held in the drug holding unit 30 is administered to the subject.

【００２２】投与後、次の投与準備に取り掛かる。この
時、全量が投与されているので、従来とは異なり、投与
に使用した薬剤注入用シリンジ２６の放射能残留量を測
定する必要がない。After administration, preparation for the next administration is started. At this time, since the entire amount has been administered, it is not necessary to measure the residual amount of radioactivity of the drug injection syringe 26 used for the administration, unlike the related art.

【００２３】次に、実際の病院で用いるのに適した具体
的な第２実施形態について詳細に説明する。Next, a specific second embodiment suitable for use in an actual hospital will be described in detail.

【００２４】本実施形態は、図２（正面から見た縦断面
図）、図３（上面から見た横断面図）、図４（図２の右
側から見た縦断面図）及び図５（要部の背面図）に示す
如く、前記第１実施形態と同様のバック１０、チューブ
１２、三方活栓付バルブ１４、１６、フィルタ１８、押
し込み用シリンジ２２、薬剤注入用シリンジ２６、薬剤
保持部３０、放射能測定器３２を、全て、固定キャスタ
４２、ブレーキ付自在キャスタ４４及び取手４６を備え
たワゴン４０に搭載して、病院内での移動を容易とした
ものである。In this embodiment, FIG. 2 (vertical sectional view as viewed from the front), FIG. 3 (transverse sectional view as viewed from above), FIG. 4 (longitudinal sectional view as viewed from the right side of FIG. 2), and FIG. As shown in the back view of the main part), the bag 10, the tube 12, the valves 14 and 16 with the three-way cock, the filter 18, the pushing syringe 22, the medicine injecting syringe 26, and the medicine holding part 30 are the same as those in the first embodiment. The radioactivity measuring devices 32 are all mounted on a wagon 40 equipped with a fixed caster 42, a freely adjustable caster 44 with a brake, and a handle 46 to facilitate movement in a hospital.

【００２５】図において、５０は、図３に示す矢印Ａの
範囲で揺動可能なバック１０用のスタンド、５２は、フ
ィルタ１０用の固定台、５４は、前記押し込み用シリン
ジ２２を保持するためのシリンジホルダ、５６は、先端
が例えばタングステン製のシールド容器２８によって遮
蔽された前記薬剤注入用シリンジ２６を保持するための
シリンジホルダ、５８は、該薬剤注入用シリンジ２６
を、図３の矢印Ｂに示す如く、駆動するためのサーボア
クチュエータ、６０は、前記薬剤保持部３０を構成する
チューブ巻取用パイプ、６２は、前記放射能測定器３２
を構成するドーズキャリブレータ、６４は、そのシール
ド、６６は、図２の背面側にパネルが固定された、ドー
ズキャリブレータ６２のコントローラ、６８は、同じく
図２の背面側に設けられた、図３の矢印Ｃに示す如く引
出し可能な、パネル引出式の操作盤、７０は、ワゴン４
０の下方に配設された主制御盤、７２は、該主制御盤７
０の上方に設けられた副制御盤、７４は、ワゴン４０上
部の前記チューブ１２、三方活栓付バルブ１４、１６、
フィルタ１８、薬剤注入用シリンジ２６等を遮蔽するた
めの、矢印Ｄに示す如く、水平方向にスライド可能な、
例えば厚さ１０ｍｍの鉛製上蓋７６を有する、例えば厚
さ２０ｍｍの鉛シールド、７８は、前記チューブ１２の
出口側に設けられた、放射性薬剤の通過を確認するため
の放射線センサ、８０は排液用ボトル、８２は、そのホ
ルダ、８４は、押し込み用シリンダ２２を収容するため
のケース、８６は、その、透明な塩化ビニール製の扉、
８８は、バッファ液廃棄用スタンドである。In the drawing, reference numeral 50 denotes a stand for the bag 10 which can swing in the range of the arrow A shown in FIG. 3, 52 denotes a fixed base for the filter 10, and 54 denotes a holder for holding the pushing syringe 22. Is a syringe holder for holding the syringe 26 for medicine injection whose tip is shielded by a shield container 28 made of, for example, tungsten, and 58 is a syringe holder for the syringe 26 for medicine injection.
As shown by an arrow B in FIG. 3, a servo actuator for driving, 60 is a tube winding tube constituting the medicine holding section 30, and 62 is a radioactivity measuring device 32
The dose calibrator 64 is a shield thereof, the reference numeral 66 is a panel fixed to the rear side of FIG. 2, and the controller of the dose calibrator 62, 68 is also provided on the rear side of FIG. The panel-pull-out type operation panel 70 which can be pulled out as shown by arrow C, 70 is a wagon 4
0, a main control panel 72 disposed below the main control panel 7.
The sub-control panel 74 provided above the zero is provided with the tube 12, the three-way cock with valves 14, 16,
As shown by an arrow D, the filter 18 and the syringe 26 for drug injection can be slid horizontally, as shown by an arrow D.
For example, a lead shield having a thickness of 10 mm and a lead cover 76 having a thickness of 20 mm, for example, a lead shield 78 having a thickness of 20 mm, a radiation sensor 78 provided on the exit side of the tube 12 for confirming passage of a radiopharmaceutical, and a drainage liquid 80 Bottle 82, its holder, 84, a case for accommodating the pushing cylinder 22, 86, its transparent PVC door,
Reference numeral 88 denotes a buffer solution disposal stand.

【００２６】本実施形態を使用するに際しては、まず、
放射性液体を含んだ薬剤注入用シリンジ２６を、スライ
ド可能な鉛シールド７４の上扉７６を開いてセットす
る。In using this embodiment, first,
The drug injection syringe 26 containing the radioactive liquid is set by opening the upper door 76 of the slidable lead shield 74.

【００２７】上扉７６を閉じて完全な遮蔽状態とした
後、サーボアクチュエータ５８を駆動して、放射性液体
の全量を、チューブ巻取用パイプ６０に巻き取られた薬
剤保持部３０に送り込む。更に、バルブ１６とコイル状
の薬剤保持部３０の入口に残る薬液は、押し込み用シリ
ンジ２２で注射用蒸留水又は生理食塩水を定められた量
吐出して、薬液全量を薬剤保持部３０に押し込む。After the upper door 76 is closed to complete the shielding state, the servo actuator 58 is driven to send the entire amount of the radioactive liquid to the medicine holding section 30 wound around the tube winding pipe 60. Further, the drug solution remaining at the inlet of the valve 16 and the coil-shaped drug holding unit 30 discharges a predetermined amount of distilled water for injection or physiological saline with the pushing syringe 22, and pushes the whole drug solution into the drug holding unit 30. .

【００２８】次いで、パイプ６０を、矢印Ｅに示す如
く、下げて、ドーズキャリブレータ６２内に入れた状態
で、放射能量を測定する。Next, the amount of radioactivity is measured with the pipe 60 lowered as shown by the arrow E and put in the dose calibrator 62.

【００２９】放射能量測定後の放射性薬剤は、サーボア
チュエータ２４により駆動される押し込み用シリンジ２
２によって、追い出（フラッシング）され、全量が被験
者に送られる。After the radioactivity measurement, the radiopharmaceutical is pushed into the pushing syringe 2 driven by the servo actuator 24.
By 2 it is flushed out and the whole amount is sent to the subject.

【００３０】本実施形態においては、この際、放射線セ
ンサ７８によって放射性薬剤の通過が確認される。な
お、この放射線センサ７８は省略することも可能であ
る。In this embodiment, the passage of the radiopharmaceutical is confirmed by the radiation sensor 78 at this time. The radiation sensor 78 can be omitted.

【００３１】本実施形態においては、操作を自動化し、
放射性液体の通過部分を、ほぼ完全にシールドしている
ので、被爆低減効果が高い。特に、接液部のフィルタ、
チューブ、三方活栓付バルブ、シリンジは、全て滅菌済
みのデスポーザブルを使用することができ、無菌の保持
が簡単にできる。又、ラインの交換も容易にできる。In this embodiment, the operation is automated,
Since the passage of the radioactive liquid is almost completely shielded, the effect of reducing the exposure is high. In particular, filters in the wetted part,
The tubes, three-way stopcock valves, and syringes can all be sterilized and disposable, and can be easily maintained aseptically. In addition, replacement of the line can be easily performed.

【００３２】なお、短寿命でない放射性医薬品について
は、それほど被爆防止の必要性は有しないので、正確な
測定は困難ではないが、本発明を適用できることは明ら
かである。It should be noted that accurate measurement is not difficult for radiopharmaceuticals that do not have a short life because they do not need to be so exposed, but it is clear that the present invention can be applied.

【００３３】[0033]

【発明の効果】本発明によれば、取扱者の放射線被曝量
を減少させ、投与量を簡単且つ正確に測定することが可
能となる。According to the present invention, the radiation exposure dose of the operator can be reduced, and the dose can be measured simply and accurately.

【図面の簡単な説明】[Brief description of the drawings]

【図１】本発明の基本的な構成を示す第１実施形態の構
成図FIG. 1 is a configuration diagram of a first embodiment showing a basic configuration of the present invention.

【図２】本発明の具体的な構成例である第２実施形態を
示す、正面から見た縦断面図FIG. 2 is a longitudinal sectional view showing a second embodiment as a specific configuration example of the present invention, viewed from the front.

【図３】同じく上面から見た横断面図FIG. 3 is a cross-sectional view of the same seen from above.

【図４】同じく右側面から見た縦断面図FIG. 4 is a vertical sectional view of the same seen from the right side.

【図５】同じく要部の背面図FIG. 5 is a rear view of the same main part.

【符号の説明】[Explanation of symbols]

１０…バック １２…チューブ １４、１６…三方活栓付バルブ １８…フィルタ ２０…注射針 ２２…押し込み用シリンジ ２６…放射性薬剤注入用シリンジ ３０…薬剤保持部 ３２…放射能測定器 ４０…ワゴン ６０…チューブ巻取パイプ ６２…ドーズキャリブレータ ２８、６４、７４、７６…シールド DESCRIPTION OF SYMBOLS 10 ... Back 12 ... Tube 14, 16 ... Three-way stopcock valve 18 ... Filter 20 ... Injection needle 22 ... Push-in syringe 26 ... Syringe for radiopharmaceutical injection 30 ... Drug holding part 32 ... Radioactivity measuring instrument 40 ... Wagon 60 ... Tube Winding pipe 62 ... Dose calibrator 28, 64, 74, 76 ... Shield

───────────────────────────────────────────────────── フロントページの続き (72)発明者 鈴木 啓文 愛媛県新居浜市惣開町５番２号 住友重機 械工業株式会社新居浜製造所内 Ｆターム(参考） 4C066 AA07 BB01 CC03 DD12 FF05 HH02 LL06 LL19 QQ43  ────────────────────────────────────────────────── ─── Continued on the front page (72) Inventor Hirofumi Suzuki 5-2 Sokai-cho, Niihama-shi, Ehime Prefecture F-term in the Niihama Works, Sumitomo Heavy Industries, Ltd. 4C066 AA07 BB01 CC03 DD12 FF05 HH02 LL06 LL19 QQ43

Claims (4)

【特許請求の範囲】[Claims] 【請求項１】放射性液体を人体に注入するための放射性
液体の注入方法において、 注入直前に、放射性液体の全量を一時的に、放射線遮蔽
された液体保持部に収容し、 該液体保持部に収容された放射性液体の放射能量を測定
した後、 該放射性液体の全量を人体に注入することを特徴とする
放射性液体の注入方法。1. A method for injecting a radioactive liquid into a human body for injecting the radioactive liquid into a human body, wherein immediately before the injection, the entire amount of the radioactive liquid is temporarily stored in a radiation-shielded liquid holding unit, and the liquid holding unit A method for injecting a radioactive liquid, comprising measuring the amount of radioactivity of a contained radioactive liquid, and then injecting the entire amount of the radioactive liquid into a human body. 【請求項２】放射性液体を人体に注入するための放射性
液体の注入装置において、 注入直前の放射性液体の全量を一時的に収容可能な液体
保持部と、 該液体保持部を遮蔽する放射線遮蔽手段と、 該液体保持部に収容された放射性液体の放射能量を測定
する放射能測定手段と、 放射能測定後の放射性液体の全量を人体に注入するため
の液体押し込み手段と、 を備えたことを特徴とする放射性液体の注入装置。2. An apparatus for injecting a radioactive liquid into a human body for injecting the radioactive liquid into a human body, comprising: a liquid holding portion capable of temporarily storing the entire amount of the radioactive liquid immediately before injection; and a radiation shielding means for shielding the liquid holding portion. And radioactivity measuring means for measuring the radioactivity of the radioactive liquid stored in the liquid holding part; and liquid pushing means for injecting the entire amount of the radioactive liquid after the radioactivity measurement into a human body. Characteristic radioactive liquid injection device. 【請求項３】請求項２において、更に、前記液体保持部
に放射性液体を送入するための放射性液体送入手段を遮
蔽する放射線遮蔽手段を備えたことを特徴とする放射性
液体の注入装置。3. An apparatus for injecting a radioactive liquid according to claim 2, further comprising radiation shielding means for shielding a radioactive liquid feeding means for feeding the radioactive liquid into said liquid holding section. 【請求項４】請求項２又は３に記載の手段が、全て、移
動可能な台車に搭載されていることを特徴とする放射性
液体の注入装置。4. An apparatus for injecting a radioactive liquid, wherein all of the means according to claim 2 or 3 is mounted on a movable carriage.
JP11166230A 1999-06-14 1999-06-14 Injection method and apparatus of radioactive liquid Pending JP2000350783A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP11166230A JP2000350783A (en) 1999-06-14 1999-06-14 Injection method and apparatus of radioactive liquid

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP11166230A JP2000350783A (en) 1999-06-14 1999-06-14 Injection method and apparatus of radioactive liquid

Publications (1)

Publication Number Publication Date
JP2000350783A true JP2000350783A (en) 2000-12-19

Family

ID=15827533

Family Applications (1)

Application Number Title Priority Date Filing Date
JP11166230A Pending JP2000350783A (en) 1999-06-14 1999-06-14 Injection method and apparatus of radioactive liquid

Country Status (1)

Country Link
JP (1) JP2000350783A (en)

Cited By (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005324007A (en) * 2004-03-02 2005-11-24 General Electric Co <Ge> System for preparing, supplying, and monitoring radiopharmaceutical, its method, and its device
WO2005118031A1 (en) * 2004-05-27 2005-12-15 E-Z-Em, Inc. System, method, and computer program product for handling, mixing, dispensing, and injecting radiopharmaceutical agents
WO2005123161A1 (en) * 2004-06-21 2005-12-29 Nemoto Kyorindo Co., Ltd Medicinal liquid injection system
EP1616587A1 (en) * 2004-07-16 2006-01-18 Universität Zürich Method and device for accurate dispensing of radioactivity
KR100589674B1 (en) * 2004-07-08 2006-06-19 사회복지법인 삼성생명공익재단 An apparatus and a method for dispense of radioactive substance
WO2007061040A1 (en) * 2005-11-25 2007-05-31 Nemoto Kyorindo Co., Ltd. Connection adaptor and connection device for liquid drug
JP2008023346A (en) * 2007-08-10 2008-02-07 Sumitomo Heavy Ind Ltd Method for distributing and administering radiation liquid, and unit
JP2008212201A (en) * 2007-02-28 2008-09-18 Natl Inst Of Radiological Sciences Automatic radioactive pharmaceutical dispensing and administering device
WO2009036443A1 (en) * 2007-09-13 2009-03-19 Molecular Insight Pharmaceuticals, Inc. Infusion and transfer system for use with radioactive agents
WO2009106961A1 (en) 2008-02-29 2009-09-03 Graziano Azzolini Hydraulic circuit for the injection of fluids for applications for radioactive diagnostic fluids in nuclear medicine
WO2009106977A1 (en) * 2008-02-29 2009-09-03 Graziano Azzolini Appliance for the injection of fluids for applications of radioactive diagnostic fluids in nuclear medicine
WO2009152326A2 (en) * 2008-06-11 2009-12-17 Bracco Diagnostics Inc. Cabinet structure configurations for infusion systems
US7862534B2 (en) 2008-06-11 2011-01-04 Bracco Diagnostics Inc. Infusion circuit subassemblies
EP2332593A3 (en) * 2009-12-14 2011-07-20 Medrad, Inc. A device and method for determining activity of radiopharmaceutical material
US8216181B2 (en) 2008-11-19 2012-07-10 Bracco Diagnostics, Inc. Apparatus and methods for support of a membrane filter in a medical infusion system
US8317674B2 (en) 2008-06-11 2012-11-27 Bracco Diagnostics Inc. Shielding assemblies for infusion systems
US8708352B2 (en) 2008-06-11 2014-04-29 Bracco Diagnostics Inc. Cabinet structure configurations for infusion systems
US9056164B2 (en) 2007-01-01 2015-06-16 Bayer Medical Care Inc. Radiopharmaceutical administration methods, fluid delivery systems and components thereof
US9056200B2 (en) 2008-06-06 2015-06-16 Bayer Medical Care Inc. Apparatus and methods for delivery of fluid injection boluses to patients and handling harmful fluids
US9108047B2 (en) 2010-06-04 2015-08-18 Bayer Medical Care Inc. System and method for planning and monitoring multi-dose radiopharmaceutical usage on radiopharmaceutical injectors
US9326742B2 (en) 2007-01-01 2016-05-03 Bayer Healthcare Llc Systems for integrated radiopharmaceutical generation, preparation, transportation and administration
US9561344B2 (en) 2003-04-08 2017-02-07 Bayer Healthcare Llc Fluid delivery systems, devices, and methods for delivery of hazardous fluids
US9597053B2 (en) 2008-06-11 2017-03-21 Bracco Diagnostics Inc. Infusion systems including computer-facilitated maintenance and/or operation and methods of use
US9707342B2 (en) 2012-06-07 2017-07-18 Bayer Healthcare Shield adapted to fit medical injector syringe
US9766351B2 (en) 2014-03-13 2017-09-19 Bracco Diagnostics Inc. Real time nuclear isotope detection
US9889288B2 (en) 2012-06-07 2018-02-13 Bayer Healthcare Llc Tubing connectors
JP2018191703A (en) * 2017-05-12 2018-12-06 日本メジフィジックス株式会社 Radioactive medicine administration device and detachable cassette
US10272263B2 (en) 2012-06-07 2019-04-30 Bayer Healthcare Llc Radiopharmaceutical delivery and tube management system
JP2019130368A (en) * 2014-03-17 2019-08-08 株式会社根本杏林堂 Injection device and device for controlling injection device
CN110478081A (en) * 2019-09-11 2019-11-22 重庆市中药研究院 A kind of animal buck test vein successive administration device and its medication
US10751432B2 (en) 2016-09-20 2020-08-25 Bracco Diagnostics Inc. Shielding assembly for a radioisotope delivery system having multiple radiation detectors
US11810685B2 (en) 2018-03-28 2023-11-07 Bracco Diagnostics Inc. Early detection of radioisotope generator end life

Cited By (82)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9561344B2 (en) 2003-04-08 2017-02-07 Bayer Healthcare Llc Fluid delivery systems, devices, and methods for delivery of hazardous fluids
JP2005326398A (en) * 2004-03-02 2005-11-24 General Electric Co <Ge> System, method and device for injecting radiopharmaceutical
JP2005324007A (en) * 2004-03-02 2005-11-24 General Electric Co <Ge> System for preparing, supplying, and monitoring radiopharmaceutical, its method, and its device
JP4695896B2 (en) * 2004-03-02 2011-06-08 ゼネラル・エレクトリック・カンパニイ System, method and apparatus for radiopharmaceutical injection
WO2005118031A1 (en) * 2004-05-27 2005-12-15 E-Z-Em, Inc. System, method, and computer program product for handling, mixing, dispensing, and injecting radiopharmaceutical agents
JPWO2005123161A1 (en) * 2004-06-21 2008-04-10 株式会社根本杏林堂 Chemical injection system
WO2005123161A1 (en) * 2004-06-21 2005-12-29 Nemoto Kyorindo Co., Ltd Medicinal liquid injection system
JP4850700B2 (en) * 2004-06-21 2012-01-11 株式会社根本杏林堂 Chemical injection system
KR100589674B1 (en) * 2004-07-08 2006-06-19 사회복지법인 삼성생명공익재단 An apparatus and a method for dispense of radioactive substance
EP1616587A1 (en) * 2004-07-16 2006-01-18 Universität Zürich Method and device for accurate dispensing of radioactivity
US8517905B2 (en) 2004-07-16 2013-08-27 University Of Zurich Method and device for accurate dispensing of radioactivity
US8852071B2 (en) 2004-07-16 2014-10-07 Bayer Medical Care Inc. Method and device for accurate dispensing of radioactivity
CN102886100A (en) * 2004-07-16 2013-01-23 苏黎世大学 Method and device for accurate dispensing of radioactivity
US9295857B2 (en) 2004-07-16 2016-03-29 University Of Zurich Method and device for accurate dispensing of radioactivity
WO2006007750A1 (en) * 2004-07-16 2006-01-26 Universität Zürich Method and device for accurate dispensing of radioactivity
US9717928B2 (en) 2004-07-16 2017-08-01 University Of Zurich Method and device for accurate dispensing of radioactivity
WO2007061040A1 (en) * 2005-11-25 2007-05-31 Nemoto Kyorindo Co., Ltd. Connection adaptor and connection device for liquid drug
US9913941B2 (en) 2007-01-01 2018-03-13 Bayer Healthcare Llc Radiopharmaceutical administration methods, fluid delivery systems and components thereof
US9326742B2 (en) 2007-01-01 2016-05-03 Bayer Healthcare Llc Systems for integrated radiopharmaceutical generation, preparation, transportation and administration
US10016618B2 (en) 2007-01-01 2018-07-10 Bayer Healthcare Llc Methods and systems for integrated radiopharmaceutical generation, preparation, transportation and administration
US9056164B2 (en) 2007-01-01 2015-06-16 Bayer Medical Care Inc. Radiopharmaceutical administration methods, fluid delivery systems and components thereof
JP2008212201A (en) * 2007-02-28 2008-09-18 Natl Inst Of Radiological Sciences Automatic radioactive pharmaceutical dispensing and administering device
JP2008023346A (en) * 2007-08-10 2008-02-07 Sumitomo Heavy Ind Ltd Method for distributing and administering radiation liquid, and unit
WO2009036443A1 (en) * 2007-09-13 2009-03-19 Molecular Insight Pharmaceuticals, Inc. Infusion and transfer system for use with radioactive agents
WO2009106977A1 (en) * 2008-02-29 2009-09-03 Graziano Azzolini Appliance for the injection of fluids for applications of radioactive diagnostic fluids in nuclear medicine
WO2009106961A1 (en) 2008-02-29 2009-09-03 Graziano Azzolini Hydraulic circuit for the injection of fluids for applications for radioactive diagnostic fluids in nuclear medicine
US9750953B2 (en) 2008-06-06 2017-09-05 Bayer Healthcare Llc Apparatus and methods for delivery of fluid injection boluses to patients and handling harmful fluids
US9056200B2 (en) 2008-06-06 2015-06-16 Bayer Medical Care Inc. Apparatus and methods for delivery of fluid injection boluses to patients and handling harmful fluids
US7862534B2 (en) 2008-06-11 2011-01-04 Bracco Diagnostics Inc. Infusion circuit subassemblies
US9607722B2 (en) 2008-06-11 2017-03-28 Bracco Diagnostics Inc. Infusion systems including computer-facilitated maintenance and/or operation and methods of use
US8317674B2 (en) 2008-06-11 2012-11-27 Bracco Diagnostics Inc. Shielding assemblies for infusion systems
US11464896B2 (en) 2008-06-11 2022-10-11 Bracco Diagnostics Inc. Integrated strontium-rubidium radioisotope infusion systems
US10994072B2 (en) 2008-06-11 2021-05-04 Bracco Diagnostics Inc. Infusion system configurations
RU2506098C2 (en) * 2008-06-11 2014-02-10 Бракко Дайэгностикс Инк. Safety assemblies for infusion systems
RU2512930C2 (en) * 2008-06-11 2014-04-10 Бракко Дайэгностикс Инк. Infusion system configurations
US8708352B2 (en) 2008-06-11 2014-04-29 Bracco Diagnostics Inc. Cabinet structure configurations for infusion systems
AU2009257435B2 (en) * 2008-06-11 2014-08-14 Bracco Diagnostics Inc. Cabinet structure configurations for infusion systems
CN102065927B (en) * 2008-06-11 2014-09-24 布拉科诊断公司 Infusion system configurations
US10991474B2 (en) 2008-06-11 2021-04-27 Bracco Diagnostics Inc. Shielding assemblies for infusion systems
US10376630B2 (en) 2008-06-11 2019-08-13 Bracco Diagnostics Inc. Integrated Strontium-Rubidium radioisotope infusion systems
CN102083484A (en) * 2008-06-11 2011-06-01 布拉科诊断公司 Shielding assemblies for infusion systems
US10335537B2 (en) 2008-06-11 2019-07-02 Bracco Diagnostics Inc. Integrated strontium-rubidium radioisotope infusion systems
US9114203B2 (en) 2008-06-11 2015-08-25 Bracco Diagnostics Inc. Infusion systems configurations
US9123449B2 (en) 2008-06-11 2015-09-01 Bracco Diagnostics Inc. Infusion system configurations
CN102056640A (en) * 2008-06-11 2011-05-11 布拉科诊断公司 Cabinet structure configurations for infusion systems
US9299468B2 (en) 2008-06-11 2016-03-29 Bracco Diagnostics Inc. Radioisotope generator system including activity measurement and dose calibration
US9299467B2 (en) 2008-06-11 2016-03-29 Bracco Diagnostics Inc. Infusion system with radioisotope detector
WO2009152322A3 (en) * 2008-06-11 2010-05-06 Bracco Diagnostics Inc. Infusion system configurations
KR101618855B1 (en) 2008-06-11 2016-05-09 브라코 다이어그노스틱스 아이엔씨. Infusion systems including computer-facilitated maintenance and/or operation and methods of use
KR20160107349A (en) * 2008-06-11 2016-09-13 브라코 다이어그노스틱스 아이엔씨. Cabinet structure configurations for infusion systems
KR101932426B1 (en) * 2008-06-11 2019-03-20 브라코 다이어그노스틱스 아이엔씨. Shielding assemblies for infusion systems
KR20160134860A (en) * 2008-06-11 2016-11-23 브라코 다이어그노스틱스 아이엔씨. Shielding assemblies for infusion systems
KR101696175B1 (en) * 2008-06-11 2017-01-23 브라코 다이어그노스틱스 아이엔씨. Cabinet structure configurations for infusion systems
WO2009152326A3 (en) * 2008-06-11 2010-04-15 Bracco Diagnostics Inc. Cabinet structure configurations for infusion systems
US9597053B2 (en) 2008-06-11 2017-03-21 Bracco Diagnostics Inc. Infusion systems including computer-facilitated maintenance and/or operation and methods of use
WO2009152326A2 (en) * 2008-06-11 2009-12-17 Bracco Diagnostics Inc. Cabinet structure configurations for infusion systems
WO2009152322A2 (en) * 2008-06-11 2009-12-17 Bracco Diagnostics Inc. Infusion system configurations
WO2009152320A3 (en) * 2008-06-11 2010-04-08 Bracco Diagnostics Inc. Shielding assemblies for infusion systems
US9717844B2 (en) 2008-06-11 2017-08-01 Bracco Diagnostics Inc. Cabinet structure configurations for infusion systems
US9750869B2 (en) 2008-06-11 2017-09-05 Bracco Diagnostics, Inc. Integrated strontium-rubidium radioisotope infusion systems
US9750870B2 (en) 2008-06-11 2017-09-05 Bracco Diagnostics, Inc. Integrated strontium-rubidium radioisotope infusion systems
WO2009152320A2 (en) * 2008-06-11 2009-12-17 Bracco Diagnostics Inc. Shielding assemblies for infusion systems
US9814826B2 (en) 2008-06-11 2017-11-14 Bracco Diagnostics Inc. Integrated strontium-rubidium radioisotope infusion systems
US8216181B2 (en) 2008-11-19 2012-07-10 Bracco Diagnostics, Inc. Apparatus and methods for support of a membrane filter in a medical infusion system
US8216184B2 (en) 2008-11-19 2012-07-10 Bracco Diagnostics, Inc. Apparatus for support of a membrane filter
US8198599B2 (en) 2009-06-05 2012-06-12 Medrad, Inc. Device and method for determining activity of radiopharmaceutical material
EP2332593A3 (en) * 2009-12-14 2011-07-20 Medrad, Inc. A device and method for determining activity of radiopharmaceutical material
CN102193101A (en) * 2009-12-14 2011-09-21 梅德拉股份有限公司 Device and method for determining activity of radiopharmaceutical material
US9108047B2 (en) 2010-06-04 2015-08-18 Bayer Medical Care Inc. System and method for planning and monitoring multi-dose radiopharmaceutical usage on radiopharmaceutical injectors
US9463335B2 (en) 2010-06-04 2016-10-11 Bayer Healthcare Llc System and method for planning and monitoring multi-dose radiopharmaceutical usage on radiopharmaceutical injectors
US10272263B2 (en) 2012-06-07 2019-04-30 Bayer Healthcare Llc Radiopharmaceutical delivery and tube management system
US9889288B2 (en) 2012-06-07 2018-02-13 Bayer Healthcare Llc Tubing connectors
US9707342B2 (en) 2012-06-07 2017-07-18 Bayer Healthcare Shield adapted to fit medical injector syringe
US10012740B2 (en) 2014-03-13 2018-07-03 Bracco Diagnostics Inc. Real time nuclear isotope detection
US9766351B2 (en) 2014-03-13 2017-09-19 Bracco Diagnostics Inc. Real time nuclear isotope detection
JP2019130368A (en) * 2014-03-17 2019-08-08 株式会社根本杏林堂 Injection device and device for controlling injection device
US10751432B2 (en) 2016-09-20 2020-08-25 Bracco Diagnostics Inc. Shielding assembly for a radioisotope delivery system having multiple radiation detectors
US11752254B2 (en) 2016-09-20 2023-09-12 Bracco Diagnostics Inc. Radioisotope delivery system with multiple detectors to detect gamma and beta emissions
US11865298B2 (en) 2016-09-20 2024-01-09 Bracco Diagnostics Inc. Systems and techniques for generating, infusing, and controlling radioisotope delivery
JP2018191703A (en) * 2017-05-12 2018-12-06 日本メジフィジックス株式会社 Radioactive medicine administration device and detachable cassette
US11810685B2 (en) 2018-03-28 2023-11-07 Bracco Diagnostics Inc. Early detection of radioisotope generator end life
CN110478081A (en) * 2019-09-11 2019-11-22 重庆市中药研究院 A kind of animal buck test vein successive administration device and its medication

Similar Documents

Publication Publication Date Title
JP2000350783A (en) Injection method and apparatus of radioactive liquid
JP4034528B2 (en) Dispensing / dosing device for radioactive liquid
JP5126738B2 (en) Method and apparatus for controlling radioactive liquid dispensing / dosing device
JP4890454B2 (en) Method and apparatus for accurately distributing radioactivity
US7712491B2 (en) Process and device for the dose dispensing of a radioactive solution
US9750953B2 (en) Apparatus and methods for delivery of fluid injection boluses to patients and handling harmful fluids
EP1755704B1 (en) System, method, and computer program product for handling, mixing, dispensing, and injecting radiopharmaceutical agents
US20100331600A1 (en) System for dispensing radio-pharmaceuticals and measuring radiation dosage of it
JP3173796B2 (en) Syringe assembly for quantitative measurement of radioactive infusate and kit having the same
JP2002306609A5 (en)
Lecchi et al. Validation of a new protocol for 18 F-FDG infusion using an automatic combined dispenser and injector system
JP2008253356A (en) Radiopharmaceutical automatic dosing device and method of dosing radiopharmaceutical using the device
JP2006017660A (en) Radioactive quantity detecting sensor, method of measuring radioactive quantity using the sensor, and radioactive chemical automatic administration device
JP5228181B2 (en) Radiopharmaceutical automatic administration device
WO2015151339A1 (en) Liquid adjustment device and liquid dispensing system
JP4584647B2 (en) Method for operating radioactive liquid dispensing device and radioactive liquid dispensing device
JP4663995B2 (en) Radiopharmaceutical synthesis administration device
JP2006015055A (en) Radioactivity quantity detecting sensor, radioactivity quantity measuring method using the sensor, and radioactive medicine automatic dosing apparatus
JP4772750B2 (en) Radiopharmaceutical solution administration apparatus and radiochemical solution administration method
JP6564600B2 (en) Chemical injection device
WO2013045421A1 (en) Device
Hichwa et al. A simple dispensing/injection system for PET

Legal Events

Date Code Title Description
A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20061205

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20070410