JP2000316526A - Medical herb containing food composition - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a food composition which is safe and good for health, and a method for preparing the composition. SOLUTION: This food composition comprises four kinds of medicinal herbs of pueraria mirifica, boesenbergia pandurata, eugenia caryophllus and glycyrrhiza glabra, and lactose and/or gelatin as a powdery filler; and the manufacturing process contains a formulation step for granules or tablets.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION This invention relates to Pueraria mirifica, Boesenbergia pandurata, Eugenia
The present invention relates to a safe and healthy food composition containing four kinds of herbs, e.g., caryophyllus (eugenia caryophllus) and glycyrrhiza glabra, and a method for producing the same.

[0002]

BACKGROUND OF THE INVENTION Southeast Asia has many herbs with medicinal effects. Certain types of herbs are known as medicines in Thailand and they have long been used medically. In particular, the genus Pueraria is known as a drug containing a large amount of estrogenic compounds. Agric. U
niv. According to Wageningen Papers 85-1 (1985), there are 25 species of the genus Pueraria, and M., a Danish botanist. N. Puerari (M.N. Puerar)
i) It is said to have been named after 1765-1845. This genus is endemic to tropical Southeast Asia, Malaysia, Polynesia and Japan. They are in bushes, forests and bushes,
Vegetation is along the roadside. Some of the cultivated and harvested species are called kudzu. In the morphological description of Pueraria mirifica, it is said that it is a woody climbing plant, perennial and has tubers reaching up to 15 cm in length and 6 cm in width. The branches are strong, about 7m in diameter
It is 5 meters long or longer, cylindrical, with parallel running grooves, covered with tight gray hair, but becomes somewhat hairless with age. Leaflets are broadly oval, lateral leaflets are distorted, 12-20 cm long and 8-14 cm wide, with long, sharp base cuts or wide wedges, green and pale gray vellus on top On the underside, gray vellus in close contact with grey-green, leaf ribs are prominent, arranged in 6-7 unequal pairs. Petioles are thick, pubescent, 5-8 mm long. In addition, the plant is distributed in Thailand, especially in deciduous forests at an altitude of 300-800 m, and on the slopes of hills, with flowering time in February or March and fruiting time in April. This plant is known in Thai as Kwao Kuer or Kwao Kua.
aoKua). The usage of this plant is as follows. Tubers have a reputation for having a rejuvenating effect (Kerr, 1932; Phya Winit, 193
3 years). Estrogen-like substances have also been found (Vanij
ivatama, 1938). Its use has been limited in some areas until renewed interest by Thai and British workers (Cain, 1960). Further studies have named the name miroestrol its estrogen-like substance and determined its chemical and physical properties. Preliminary clinical studies have shown that miroestrol produces a significant estrogenic effect but, depending on the dose, can have considerable adverse toxicological consequences (Cain, 1960). The prescription in Thailand is to take dry roots with honey without purification. In the Japanese patent publication, some prior art as a food composition containing a herb, for example,
JP 10-286079, JP 10-229852, JP 10-155
No. 435, JP-A-10-136938, JP-A-10-136899, JP-A-9-238657, JP-A-9-175994, JP-A-9-56345,
There are JP-A-8-70829 and JP-A-8-38123. In addition, Japanese people have long used plants of the genus Pueraria as food, and Pueraria triloba (pueraria)
triloba) is called kuzu in Japan and ko in China and is edible. However, there is no prior art literature on Pueraria mirifica as a food composition.

[0003]

DETAILED DESCRIPTION OF THE INVENTION The present invention comprises, as a first aspect, a food composition comprising the herb Pueraria mirifica.

As a second point, the present invention relates to (i) about 20%
About 50% of Pueraria mirifica
ica) extract, (ii) about 20% to about 30% boesenbergia concentrate, (iii) about 5% to about 20%
% Eugenia, (iv) about 0.1% to about 10%
A food composition comprising glycyrrhiza glabra.

[0005] Thirdly, the present invention includes a method for producing a food composition comprising the herb Pueraria mirifica comprising a drying step, a pulverizing step, a re-drying step and a sieving step.

[0006] The present invention provides a novel food composition comprising the herb Pueraria mirifica. Herb Pueraria mirifica (pueraria)
The medical effect of mirifica) is known as an estrogenic effect. In fact, this herb contains miroestrol, represented by the following chemical formula:

[0007]

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The present invention includes the herb in 20% to 50% wt tablets, with 30% being suitable for best results. The effects of the present invention show estrogen-like effects as described below.

For the present invention, three further different herbs are included to make the food composition safer and healthier.

[0010] The second herb boesenbergia pandurata has a different name, Kaempferia pandur.
ata Roxb), sometimes defined as Gastrochilus panduratus Roxb. They are known in Thailand as karachai
It is. It is also a member of the ginger family in Thailand where fresh rhizomes are used in cooking and medicine. camphor,
Contains oils containing cineol and methylcinnamic acid. The present invention uses this herb for additional medical effects.

The third herb Eugenia kalliofilus (e)
ugenia caryophllus belongs to the genus Eugenia or the genus Syzygium. This herb is a well-known spice commonly called clove. The present invention uses this herb as an additional spice.

The fourth herb glycyrrhiza glabra
rrhiza glabra belongs to the genus Glycyrrhiza. There are 30 species of the genus Glycyrrhiza, which are herbs or shrubs. They also plant in temperate and temperate regions on all continents,
Most species are vegetated in the Mediterranean region of Eastern Europe and in Western Asia. Many species have roots such as triterpenoidsapoin, glycyrrhetinic acid (gl
ycyrrhetic acid or glycyrrhetic
has a characteristic sweet liquorice flavor by _{izinic acid) C 42 H 62 O} 16. The method of use of licorice root and its extract is long as a laxative, expectorant and demulcent, in confectionery, to flavor tobacco, in the manufacture of pills and troches, and for similar purposes. Has been established in the meantime. In the present invention, this herb is used as a sweet component.

[0013]

EXAMPLES Production Examples: Four kinds of herbs Pueraria mirifica, Boesenbergia
Pandurata (boesenbergia pandurata), Eugenia caryophllus, glycyrrhiza glabra, were washed separately, dried in an oven at 60 ° C, crushed, dried again in an oven at 50 ° C, 0.42 Sift to mm. The sieved herbs are mixed in the following weight ratios: Pueraria mirifica 45%, Boesenbergia pandurata
35% Eugenia caryops
hllus) 15%, glycyrrhiza
glabra) 5% The herb prepared above is mixed with about 32% lactose, and then gelatin is added as a binder and mixed. Its appearance is a homogeneous mixture. Thereafter, the homogeneous mixture is molded on a granulator. Final product is 20
0 mg / tablet. The contents of the tablet are as follows. Pueraria mirifica (pueraria mirifica) 31.5%, boesenbergia pandurata (boesenbergia pandur)
ata) 24.5%, Eugenia cariofilus (eugenia)
caryophllus) 10.5%, Glycyrrhiza glabra (gl
ycyrrhiza glabra) 3.5%, lactose 22.2%, gelatin 3.1%, talc 0.45%, corn starch 4.25%

Experimental Example: 100 women were given 250 mg tablets three times a day. The results after 4 weeks are shown in the following table.

[0015]

[Table 1]

[0016]

[Table 2]

[0017]

According to the present invention, a safe and healthy food composition and a method for producing the same can be provided.

 ──────────────────────────────────────────────────の Continued on the front page (71) Applicant 599060607 126 / 62-65 TANYATHORN B LDG. SOI VATCHARAPOL RAMINDRA ROAD, THAN RANG BANGKHEN BANGK OK 10230, THAILAND F term (reference) 4B018 MD20 MD29 MD61 ME02 ME14 MF06 MF07 MF08

Claims (8)

[Claims] 1. The herb Pueraria mirifica (pueraria)
mirifica). 2. Boesenbergia
Genus, eugenia, glycyrriza
A food composition according to claim 1, comprising one or more herbs selected from the genus hiza). 3. Pueraria mirifica (pueraria mifica)
rifica, boesenbergia pandurata (boesenbe)
rgia pandurata), Eugenia kalliofilus (eug)
enia caryophllus), glycyrriza glabra (glycy)
A food composition according to claim 2, comprising a herb of rrhiza glabra). 4. The method according to claim 1, wherein (i) about 20% to about 50% of Puerariamirifica extract, (ii) about 20%
From about 30% boesenbergia concentrate, (iii) about 5% to about 20% eugeni
The food composition of claim 1, comprising: a), (iv) about 0.1% to about 10% glycyrrhiza glabra. 5. The food composition according to claim 1, further comprising lactose and / or gelatin as an additive. 6. The food composition according to claim 1, wherein the food composition is granular or tablet. 7. A herb herb comprising a drying step, a pulverizing step, a re-drying step and a sieving step.
ia mirifica). 8. The production method according to claim 7, comprising a molding step.