JP2000266643A - Granule sample quantitative distributor - Google Patents

Abstract

PROBLEM TO BE SOLVED: To make a granule sample easily quantitative distributable without spilling the sample by forming a recessed metering part for quantitatively retaining the granule sample at the frequent appearance peripheral drum of a rod that is inserted so that it can travel in the axial direction in a cylindrical body and is provided so that it can frequently appear from one end part of the cylindrical body. SOLUTION: The distributor 1 is formed in a pen type by a rod 3 that is inserted so that it can travel in the axial direction of a cylindrical body 2, and the rod 3 is provided so that its tip can frequently appear from the tip of the cylindrical body 2. The cylindrical body 2 consists of a cylindrical tip part 21 and a cylindrical source part 22, a small-diameter insertion hole 23 and a large-diameter insertion hole 24 are formed in penetration in the cylindrical tip part 22, the large-diameter insertion hole 24 continues to an insertion hole 25 with the same diameter being formed at the cylindrical source part 22, and a rod insertion hole 26 in the axial direction is formed by the small-diameter insertion hole 23, the large-diameter insertion hole 24, and the insertion hole 25. The rod 3 consists of a small-diameter rod part 31 and a large-diameter rod part 22, and a recessed metering part 33 for quantitatively filling the particle is formed at the peripheral drum part of the frequent appearance part that frequently appear from the tip of the cylindrical body 2.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a powder and granule sample dispenser for dispensing a predetermined amount of a powder or granule sample such as a powder or granule into a reaction vessel such as a test tube or a flask.

[0002]

2. Description of the Related Art Conventionally, in a quantitative dispensing operation of a powder sample, a small amount of a sample is placed on a medicine package placed on a balance using a spoon, and the weight is measured to reach a required amount. This was done by transporting by wrappers.

[0003]

Therefore, the operation has been complicated and time-consuming. In particular, in the synthesis of reagents called combinatorial chemistry, which has attracted attention in drug discovery research in recent years, a large amount of work time has been required because powdery and granular samples are put in many reaction vessels.

Accordingly, an object of the present invention is to provide a powder / particle sample quantitative dispenser capable of dispensing a powder / particle sample simply and quantitatively without spilling the powder sample.

[0005]

In order to achieve the above object, a first powdery and granular sample dispenser according to the present invention is inserted into a cylinder and movably inserted in the cylinder in the axial direction. A rod is provided so as to be able to protrude and retract from one end of the cylindrical body, and a concave measuring portion for holding a powder sample in a fixed amount is formed in a peripheral body of the protruding and protruding portion of the rod. Forming a sample filling hole on the peripheral wall of the cylindrical body, which can fill the measuring portion of the rod stored in the cylindrical body with the granular material sample, on the peripheral wall of the cylindrical body; It is possible to provide a hopper for supplying and filling the granular material sample to the measuring section via the filling hole, and to provide a funnel for receiving the granular material sample falling from the measuring section at the end of the rod of the cylindrical body on the side where the rod comes out. .

[0006] The second powder / particle sample dispenser has a hopper portion and a funnel portion, and has a main body formed with an insertion hole extending from the outer wall on the hopper portion side to the funnel portion through the bottom of the hopper portion. A rod that is movably inserted into the insertion hole and that is provided so as to be able to protrude and retract into the hopper and the funnel, and a metering part is formed on a peripheral body of the protruding part of the rod.

[0007] Further, the third powder sample dispenser is
A main body having a hopper portion, a plurality of insertion holes formed in parallel from one outer wall to the other outer wall through the bottom portion of the hopper portion, and movably inserted into the respective insertion holes; With a rod provided on the outer wall of the
A weighing portion is formed on a peripheral body portion of the protruding and retracting portion of the rod, and the rods are connected to each other by a connecting member that moves each rod at the same time. A funnel portion corresponding to each rod can be formed on the other outer wall side.

[0008] The measuring section in these powdery and granular material sample dispensers may be a concave portion having a bottom and a through hole or a notch crossing the peripheral body.

A fourth particle sample dispenser having a hopper portion, a main body having a flat insertion hole penetrating from one outer wall to the other outer wall through the bottom of the hopper portion;
A plate which is movably inserted into the insertion hole and is provided so as to be able to protrude and retract from the other outer wall from the hopper portion, wherein a plurality of through-metering holes are formed in the protruding portion of the plate. . A funnel portion corresponding to each through-metering hole may be formed on the other outer wall side.

[0010]

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS Hereinafter, the present invention will be described in more detail based on embodiments shown in the drawings. FIG. 1 shows a first embodiment of the present invention, in which a powdery and granular sample quantitative distributor 1 is, for example, inserted into a cylindrical cylinder 2 and movably inserted in the cylinder 2 in the axial direction. The rod 3 is formed in a pen shape, and the rod 3 is provided so that its tip can protrude and retract from the tip of the cylindrical body 2.

The cylindrical body 2 includes a cylindrical portion 21 and the cylindrical portion 2.
1 and a cylinder base portion 22 screwed to the rear portion,
A small-diameter insertion hole 23 extending from the tip to the middle portion is formed in the cylinder tip 21.
And a large-diameter insertion hole 24 extending from the intermediate portion to the rear end is formed continuously through the large-diameter insertion hole 24. The large-diameter insertion hole 24 is continuous with the same-diameter insertion hole 25 formed in the cylinder base portion 22, Small diameter insertion hole 2
3. The rod insertion hole 26 in the axial direction is formed by the large diameter insertion hole 24 and the insertion hole 25. The rear end of the tube base 22 is closed, and the rear end of the rod insertion hole 26 has a bottomed shape. A slit 2 is provided on the rear side surface of the cylinder base 22.
7 is formed in the axial direction, and the length of the slit 27 in the axial direction is a length for protruding the distal end of the rod 3 from the distal end of the cylindrical body 2.

The rod 3 is a small-diameter rod portion 3 on the distal end side.
1 and a large-diameter rod 32 screwed to the rear of the small-diameter rod 31. The small-diameter rod portion 31 is inserted through the small-diameter insertion hole 23, and a concave measuring portion 33 capable of quantitatively filling the granular material sample is formed in a peripheral body portion of a protruding and protruding portion that protrudes and protrudes from the tip of the cylindrical body 2. I have. The large-diameter rod portion 32 is inserted through the large-diameter insertion hole 24 and the insertion hole 25, and an operation member 34 for projecting and retracting the rod 3 is screwed through the slit 27 on the peripheral surface of the rear end portion. The rod 3 is provided with a step 28 of the rod insertion hole 26.
The spring is biased in the backward direction by a return spring 36 disposed between the cylinder 3 and the step portion 35 of the rod 3, and the measuring portion 33 is normally retracted and stored in the cylindrical body 2. Then, the operating member 34 is connected to the return spring 3
When the finger is pressed in the distal direction against the spring force of No. 6, the measuring unit 33
Is exposed from the tip of the cylindrical body 2.

The length of the small-diameter rod portion 31 is
Is formed to be longer than the entire length of the small-diameter insertion hole 23 so that the measuring portion 33 can protrude from the distal end of the cylindrical body 2 when the step portion 35 is advanced from the retreat position and the step portion 35 is advanced by the step portion 28. ing. The relationship between the outer diameter of the small-diameter rod portion 31 and the inner diameter of the small-diameter insertion hole 23 is as follows.
That is, the outer diameter of the small-diameter rod portion 31 is set to be slightly smaller than the inner diameter of the small-diameter insertion hole 23, whereby the powder sample can be accurately transferred to the measuring section 33. Is fixedly filled.

With this configuration, when the operating member 34 is pushed by the finger in the distal direction to cause the distal end of the rod 3 to protrude from the cylindrical body 2 and to be inserted into the powder sample, the measuring section exposed from the cylindrical body 2 33 is filled with the powder sample. Subsequently, when the finger is released from the operating member 34, the tip of the rod 3 is retracted into the cylindrical body 2 by the spring force of the return spring 35, and at this time, the powder sample filled in the measuring section 33 has a small diameter. The powder sample is cut at the diameter of the insertion hole 23 and
3 is filled and held by the volume. When the operating member 34 causes the distal end of the rod 3 to protrude from the cylindrical body 2 on the reaction vessel, the powder sample filled and held in the measuring section 33 falls into the reaction vessel, and the powder sample is removed. Dispensing can be reliably performed without spillage.

When the amount of distribution due to this transfer does not reach the desired amount, the above operation can be repeated or replaced with a small-diameter rod having a large capacity in the measuring section 33. Further, since the cylindrical body 2 and the rod 3 can be disassembled, each part can be easily cleaned, and any dirt can be easily removed.

In the embodiment of FIG. 1, the concave measuring portion 33 is formed in a concave portion having a bottom.
As in the first modified example of FIG. 2, a through-hole that crosses the peripheral body portion of the projecting portion of the small-diameter rod portion 31 at right angles to the axial direction, or as in the second modified example of FIG. As in the case of a through hole that traverses, or a third modification example of FIGS. 4 and 5, a notch that traverses the circumferential body in the axial direction can be formed.

FIG. 6 shows a second embodiment of the present invention. As in the first embodiment, a pen-shaped powder sample dispenser 1 is provided with a powder sample. This is a configuration including a hopper 4 for storage. In the following embodiments, the same elements as those in the first embodiment are denoted by the same reference numerals, and description thereof will be omitted.

The distributor 1 is provided on the peripheral wall of the cylindrical body 2.
The weighing section 33 of the rod 3 drawn therein is formed with a sample filling hole 29 through which a powder sample can be filled, and the hopper 4 is provided at a position communicating with the sample filling hole 29. The powder sample in the hopper 4 is supplied and filled from the lower part of the hopper 4 to the through-hole-shaped measuring section 33 through the sample filling hole 29.

If the position of the sample filling hole 29 is formed at a position corresponding to the measuring portion 33 when the rod 3 is stored at the innermost position in the cylindrical body 2, the measuring portion 3 which is always at the retracted position is provided.
Although it is desirable to perform the quantitative filling of the granular material sample from the hopper 4 into the hopper 3 satisfactorily, if it is formed between this position and the position from the tip to the tip of the cylindrical body 2, the measuring unit 33 is moved forward by the rod 3. When passing through the position of the sample filling hole 29, the granular material sample is supplied from the hopper 4 to the measuring section 33, and the measuring section 33 can be fixedly filled.

Further, in order to make the measuring portion 33 face the sample filling hole 29, the tip of the pin 5 protruding into the tube tip portion 21 is engaged with the axial groove 37 formed in the small-diameter rod portion 31 so that the rod is engaged. The rotation around the third axis is restricted.

The rear end of the large-diameter rod portion 32 protrudes from the rear wall of the cylinder base 22, and an operating member 34 is attached to the protruding rear end. The restriction on the retraction of the rod 3 is such that the pins 38 projecting from the circumferential body of the large-diameter rod 32
This is performed by abutting the rear end walls of the first and second parts 27, 27.

According to this configuration, the granular material sample filled in the measuring section 33 from the hopper 4 can be distributed to the reaction vessel by projecting the rod 3 from the cylindrical body 2. It can be distributed continuously by motion. When the hopper 4 is not provided, the powder sample is filled into the measuring section 33 through the sample filling hole 29 by pushing the tip of the cylindrical body 2 until the sample filling hole 29 is inserted into the powder sample. can do.

In the third embodiment shown in FIG. 7, an adapter 43 for mounting a commercially available reagent bottle can be attached to the hopper 4 in the second embodiment. In addition, the commercially available reagent bottle may be attached to the hopper 4 by threading or sliding.

In the fourth embodiment shown in FIG. 8, a funnel 6 for receiving a powder sample dropped from the measuring section 33 is provided at the end of the cylindrical body 2 at the projecting end of the rod tip. Can be prevented from scattering of the powdery sample that is distributed and dropped. The funnel 6 can be provided at the tip of the cylindrical body 2 of the pen-type granular material sample dispenser 1 as in the first embodiment.

In the fifth embodiment shown in FIGS. 9 and 10, the operation of pulling out the rod 3 from the cylindrical body 2 having the hopper 4 exposes the measuring section 33 from the cylindrical body 2 so that the powder of the measuring section 33 is supplied to the reaction vessel. This is for quantitatively distributing the granular sample. Rod 3
The retreat limit is performed by the rear end of the rod 3 abutting the rear wall of the cylindrical body 2. In this embodiment, the cylinder 2 is provided below the hopper 4. However, the cylinder 2 is provided on one side of the bottom of the hopper 4, and the rear end of the cylinder 2 is opened to open the hopper 4. The measuring section inserted into the hopper 4 may be exposed to the outside from the cylinder 2 through a sample filling hole formed in the side wall of the cylinder 2, and the cylinder 2 may be omitted.

The sixth embodiment shown in FIG.
a and a funnel part 6a, an insertion hole 26 penetrating from the outer wall on the hopper part side to the funnel part 6a through the bottom of the hopper part 4a.
And a rod 3 which is movably inserted into the insertion hole 26 and is provided so as to be able to protrude and retract into the hopper portion 4a and the funnel portion 6a. A through-hole-shaped measuring portion 33 is formed in a peripheral body portion of the projecting portion of the rod 3.

Then, by the movement of the rod 3, the powdery or granular material sample in the hopper 4a is filled in the measuring section 33 and the funnel section 6 is filled.
Discharge and distribute at a. In addition, this embodiment is the second embodiment.
An operating member 34 and a pin 38 similar to those of the embodiment are provided. With this configuration, the handling of the distributor 1 is improved, and one-handed operation is possible. Body samples can be distributed, resulting in excellent operability.

The seventh embodiment shown in FIGS. 12 and 13 has a hopper portion 4a, and eight rows of insertion holes 26 penetrating from one outer wall to the other outer wall through the bottom of the hopper portion 4a. The main body 7 is formed, and the rod 3 is movably inserted into each of the insertion holes 26 and is provided so as to be able to protrude and retract from the hopper section 4a to the other outer wall. A measuring portion 33 having a through-hole shape is formed in a peripheral body portion of the protruding and retracting portion of the rod 3. The rods 3 are connected to each other by a connecting member 71 that moves the rods 3 at the same time.

In this embodiment, eight rows of insertion holes 26 have been described. However, this is because the reaction vessels of combinatorial chemistry are often arranged in eight rows.
The invention is not limited to this number. Further, a funnel portion 6a corresponding to each rod 3 may be provided on the other outer wall side.

In the second to seventh embodiments,
Although the measuring portion 33 is formed in a through-hole shape, when the rod 3 is provided so as to be able to rotate around the axis, the concave portion having a bottomed shape used in the first embodiment can also be used.

In the eighth embodiment shown in FIG. 14, instead of the insertion hole 26 and the rod 3 of the seventh embodiment, a flat insertion hole 26a and a hopper are movably inserted through the insertion hole 26. And a plate 3a provided to be able to protrude and retract from the other outer wall from the portion 4a.
a is formed. Further, on the other outer wall side, a funnel portion 6a corresponding to each through-metering hole 33a may be provided.

FIGS. 15 and 16 show that the powdery and granular material samples are automatically placed in a multi-row and multiple reaction vessel by using the multi-row type powder and granular material sample dispenser of the seventh and eighth embodiments. 1 shows an example of a device for distributing. This device includes a controller 81
The pinion 82 of the motor whose rotation is controlled by the rod 3 or the rack 83 of the plate 3a
Container case 84 in which reaction vessels are stored in parallel in multiple rows and multiple rows
Is placed on a screw conveyor 86 of a motor 85 whose rotation is controlled by the controller 81, and the rod 3
Alternatively, the container case 84 is sequentially advanced in accordance with the reciprocating movement of the plate 3a, and the powder sample is automatically distributed to each reaction container of the container case 84. As shown in FIG. As shown in FIG. 15, the powdery or granular material filled in the through hole 33a or 33 is exposed to the other outer wall of the main body 7 or the funnel 6a, and the powdery or granular material sample is placed in the first series of the container case 84. The liquid is dropped into the reaction vessel, and this operation is sequentially repeated to automatically perform quantitative dispensing to the second and subsequent reaction vessels sequentially moving in the direction of the main body 7.

[0033]

As described above, the powdery and granular sample dispenser according to the present invention is provided with a powdery material filled in the measuring part by protruding and retracting the measuring part for quantitatively holding the particulate material sample by a sliding action. The quantitative sample can be easily dispensed without spilling the granular sample into the reaction vessel. In addition, the provision of the hopper enables continuous distribution of the powder sample. Further, by providing the funnel, the scattering of the powder sample at the time of the distribution operation can be prevented. In addition, by arranging a plurality of measuring units in parallel, distribution to a multi-row / multi-row reaction vessel can be performed efficiently.

[Brief description of the drawings]

FIG. 1 is a cross-sectional view illustrating a first embodiment of a powder sample dispenser according to the present invention.

FIG. 2 is a partial cross-sectional view showing a first modification of the measuring section.

FIG. 3 is a partial cross-sectional view showing a second modification of the measuring section.

FIG. 4 is a partial cross-sectional view showing a third modification of the measuring section.

FIG. 5 is a sectional view taken along line VV of FIG. 4;

FIG. 6 is a sectional view showing a second embodiment of the distributor according to the present invention.

FIG. 7 is a sectional view showing a third embodiment of the distributor of the present invention.

FIG. 8 is a sectional view showing a fourth embodiment of the distributor according to the present invention.

FIG. 9 is a sectional view showing a fifth embodiment of the distributor of the present invention in a normal state.

FIG. 10 is a cross-sectional view showing the operation of the fifth embodiment of the distributor of the present invention.

FIG. 11 is a sectional view showing a sixth embodiment of the distributor of the present invention.

FIG. 12 is a front sectional view showing a seventh embodiment of the distributor of the present invention.

FIG. 13 is a sectional view taken along line XIII-XIII in FIG. 12;

FIG. 14 is a front sectional view showing an eighth embodiment of the distributor of the present invention.

FIG. 15 is a schematic view showing an operation state of the distributor of the present invention by the automatic distribution device.

FIG. 16 is a schematic view showing the same operation state.

[Explanation of symbols]

1 ... powder and granular material sample dispenser, 2 ... cylinder, 26, 26a ...
Insertion hole, 29: sample filling hole, 3: rod, 3a: plate,
33: measuring section, 33a: through measuring hole, 4: hopper, 4
a: hopper, 6: funnel, 6a: funnel, 7: body

Claims (11)

[Claims] 1. A powdery and granular material sample comprising: a cylindrical body; and a rod which is inserted into the cylindrical body so as to be movable in the axial direction and is provided so as to be able to protrude and retract from one end of the cylindrical body. Characterized in that it has a concave measuring section for quantitatively holding the sample. 2. The powder particle according to claim 1, wherein a sample filling hole through which the powder sample can be filled in the measuring section stored in the cylinder is formed through the peripheral wall of the cylinder. Body sample dispenser. 3. The granular material sample according to claim 2, wherein a hopper for supplying the granular material sample to the measuring section via the sample filling hole is provided on a peripheral wall of the cylindrical body. Dispenser. 4. A funnel for receiving a powdery material sample falling from a measuring section is provided at an end of the cylindrical body on a rod projecting side. Specimen dispenser for powder samples. 5. A main body having a hopper portion and a funnel portion, having a through hole extending from the outer wall on the hopper portion side to the funnel portion through the bottom of the hopper portion, and movably inserted through the insertion hole. A powder sample dispenser, comprising: a rod provided in a hopper section and a funnel section so as to be able to protrude and retract, and a measuring section formed around a body of the protruding section of the rod. 6. A main body having a hopper portion, a plurality of insertion holes formed in parallel from one outer wall to the other outer wall through the bottom of the hopper portion, and movably inserted through the respective insertion holes. A rod provided so as to be able to protrude and retract from the hopper portion to the other outer wall, and a measuring portion is formed in a peripheral body portion of the protruding and retracting portion of the rod, and the rods are connected to each other by a connecting member that simultaneously moves each rod. A powder material sample dispenser characterized in that: 7. A funnel portion corresponding to each rod is formed on the other outer wall side.
The powder sample dispenser according to the above. 8. The dispenser according to claim 1, wherein the measuring section is a concave portion having a bottom. 9. The dispenser according to claim 1, wherein the measuring section is a through-hole or a notch crossing the peripheral body. 10. A main body having a hopper portion and having a flat insertion hole penetrating from one outer wall to the other outer wall through the bottom portion of the hopper portion, movably inserted through the insertion hole, A plate provided so as to be able to protrude and retract from the hopper to the other outer wall, wherein a plurality of through-metering holes are formed in the protruding portion of the plate. 11. The dispenser according to claim 10, wherein a funnel corresponding to each of the through-holes is formed on the other outer wall side.