JP2000247813A - Antiseptic of wood - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain an antiseptic of wood, capable of manifesting excellent antiseptic activities for the wood in practical application by using two well- known compounds having antiseptic activities in combination as active ingredients. SOLUTION: This antiseptic contains (A) 4,6-dimethyl-2-(6-phenylpyridin-2-yl) pyrimidine of formula I in combination with (B) N-(1,1,3-trimethyl-2-oxa-4- indanyl)-5-chloro-1,3-dimethylpyrazol-4-carboxylic acid amide as active ingredients. The components A and B can be used as a mixed product as it is, but preferably used by mixing the components with a solid, liquid or gas carrier to prepare a preparation such as a floable formulation and a dust formulation. The ratio of the mixed components A to B in weight is preferably 1 of the component A to 0.1-50 of the component B. As a result, the antiseptic of wood manifesting extreme cooperative effect is provided.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

[0001] The present invention relates to a wood preservative.

[0002]

2. Description of the Related Art Wood is generally exposed to severe conditions such as outdoors under direct sunlight or rainfall for a long period of time, and is usually used in soil such as agricultural fungicides. However, it is difficult to obtain a wood preservative effect that can be practically used by using an easily degradable chemical that hardly remains for a long time. Until now, various wood preservatives have been developed and used.However, these wood preservatives cannot be said to have a sufficient wood preservative effect, and it is desired to develop a wood preservative having better performance. It is rare.

[0003]

Means for Solving the Problems The present inventors have conducted intensive studies in such a situation, and as a result, formula 3

Embedded image And 4,6-dimethyl-2- (6-phenylpyridin-2-yl) pyrimidine represented by the formula:

Embedded image Wood preservatives containing N- (1,1,3-trimethyl-2-oxa-4-indanyl) -5-chloro-1,3-dimethylpyrazole-4-carboxylic acid amide represented by The present invention was found to have a wood preservative effect. That is, the present invention relates to 4,6-dimethyl-2- (6-phenylpyridine-2-
Yl) pyrimidine (hereinafter referred to as compound A) and N- (1,1,3-trimethyl-2-oxa-4-indanyl) -5-chloro-1,3-dimethylpyrazole- A wood preservative (hereinafter, referred to as the present composition) containing 4-carboxylic acid amide (hereinafter, referred to as compound B) as an active ingredient.

[0004]

BEST MODE FOR CARRYING OUT THE INVENTION Compound A is disclosed in JP-A-8-59411.
In Japanese Patent Application Laid-Open No. 5-310512, Compound B shows its wood preservative effect. The wood preservative effect obtained by mixing these compounds is, as is clear from the Examples described later, Exceeding the range expected from the potency of each component, the composition of the present invention has a remarkable synergistic effect.

When the composition of the present invention is used as a wood preservative, a mixture of Compound A and Compound B may be used as it is without adding any other components. Mix with a carrier or gas carrier and add surfactants and other adjuvants if necessary, oils, emulsions, wettable powders, suspensions in water, flowables such as emulsions in water, powders, aerosols Etc. and apply it. In these preparations, compound A and compound B are usually contained in a total amount of 0.01 to 90% by weight, preferably 0.1 to 50% by weight.
% By weight. Further, the mixing ratio between the compounds A and B is as follows:
In terms of weight ratio, compound B is usually 0.1 to compound A1.
The ratio is 50, preferably 0.2 to 5.

[0006] As the solid carrier used in the formulation, for example, clays (kaolin clay, diatomaceous earth, synthetic hydrous silicon oxide, bentonite, fubasami clay, acid clay, etc.), talcs, ceramics, and other inorganic minerals (sericite) , Quartz, sulfur, activated carbon, calcium carbonate, hydrated silica, etc.) and the like, and liquid carriers include, for example, water, alcohols (ethanol, isopropanol, 3-methyl-3-methoxybutanol). , Glycols such as polyethylene glycol, etc.), ketones (acetone, methyl ethyl ketone, etc.),
Aromatic hydrocarbons (benzene, toluene, xylene, alkylbenzene, methylnaphthalene, etc.), aliphatic hydrocarbons (hexane, cyclohexane, kerosene, light oil, etc.), esters (ethyl acetate, butyl acetate, isopropyl myristate, etc.) Fatty acid esters, 3-methyl-3-
Methoxybutyl acetate, etc.), nitriles (acetonitrile, isobutyronitrile, etc.), ethers (diisopropyl ether, dioxane, etc.), acid amides (N,
N-dimethylformamide, N, N-dimethylacetamide, etc.), halogenated hydrocarbons (dichloromethane, trichloroethane, carbon tetrachloride, etc.), dimethyl sulfoxide, vegetable oils such as soybean oil, cottonseed oil, etc. (These may be used in combination. And the gaseous carrier, that is, the propellant, for example, CFC gas, butane gas, LP
G (liquefied petroleum gas), dimethyl ether, carbon dioxide and the like.

Examples of the surfactant include alkyl sulfates, alkyl sulfonates, alkyl aryl sulfonates, alkyl aryl ethers and polyoxyethylenates thereof, polyethylene glycol ethers, polyhydric alcohol esters, sugar alcohols Derivatives and the like. Examples of pharmaceutical auxiliaries such as fixatives and dispersants include casein, gelatin, polysaccharides (starch, gum arabic, cellulose derivatives, alginic acid, etc.), lignin derivatives, bentonite, sugars, synthetic water-soluble polymers (polyvinyl alcohol) , Polyvinylpyrrolidone, polyacrylic acids, etc.), and examples of the stabilizer include PAP (acidic isopropyl phosphate), BHT
(2,6-di-tert-butyl-4-methylphenol), BHA (mixture of 2-tert-butyl-4-methoxyphenol and 3-tert-butyl-4-methoxyphenol), vegetable oil, mineral oil, Examples include surfactants, fatty acids or esters thereof. Formulations of flowables (suspended or emulsified in water) are generally prepared by adding a total of 1 to 75% of compound A and compound B to 0.5 to 15%.
% Of a dispersant, 0.1 to 10% of a suspending aid (for example, a protective colloid or a compound imparting thixotropic properties), 0 to 1%
Finely dispersed in water containing 0% of suitable adjuvants (eg antifoaming agents, rust inhibitors, stabilizers, spreading agents, penetration aids, antifreezing agents, antibacterial agents, fungicides, etc.) It is obtained by doing. It is also possible to use an oil in which the compound A and the compound B hardly dissolve in place of water to make a suspension in oil. As the protective colloid, for example, gellanin, casein, gums, cellulose ether, polyvinyl alcohol and the like are used. Examples of the compound imparting thixotropic properties include bentonite, aluminum magnesium silicate, xanthan gum, polyacrylic acid and the like.

The preparation thus obtained is used as it is or after dilution with water or the like. Usually oils, powders,
Granules, aerosols, etc. are applied to wood as it is,
Emulsions, wettable powders, flowables, etc. are usually 0.01 to 1 with water.
0% by weight of active ingredient, preferably 0.05-5% by weight
It is diluted and applied so that the amount of the active ingredient becomes. Each of these application rates and application concentrations depends on the type of formulation, application time,
It varies depending on the application place, application method, kind of wood rot fungus, degree of damage, etc., and can be increased or decreased without being concerned with the above range. The composition of the present invention is dipped, sprayed,
By treating wood (including bamboo) by means of surface treatment such as coating or by pressure injection or vacuum injection, or by adding it to a plywood adhesive (for example, phenol resin, melamine resin, urea resin, etc.), It can also be used as an agent for controlling wood rot fungi such as building materials. The composition of the present invention is preferably used as a surface treatment agent for wood, in which case, usually, an oil agent is used as a formulation, and the oil agent is usually 50 to 200 g per m ² of wood, and the amount of active ingredient is usually 0 to ² g per m ² of wood. Use 1 to 10 g.

Wood rot fungi that can be controlled by the composition of the present invention include, for example, Kawatake mushroom (Coriolus versicolor),
Streaked mushroom (Tyromyces palustris), Namidae mushroom (Serpula lacrymans), Ginkgo mushroom (Paxillus panu)
oides), Idtake (Coniophora puteana), Kikaigaratake (Gloeophyllum sepiarium), Chilimentake (Gloeophyllum trabeum), Chokeanatake (Antrod)
ia xantha), Matsuo-ji (Lentinus lepideus), Watagaretake (Antrodia sinuosa), Suehirotake (Schi)
ozophyllum commune, Hiitake (Pycnoporus cocci)
neus), and examples of wood to be controlled include beech, cedar, and red pine.

[0010] The composition of the present invention may also contain other wood preservatives,
It can be mixed with or used in combination with insecticides, acaricides, termites (termite control agents), repellents, fungicides, and synergists. Examples of such insecticides, acaricides, termites, and repellents include one or more selected from the following groups.
Pyrethroid compounds, for example, arethrin, cyfluthrin, permethrin, cypermethrin, deltamethrin, cyhalothrin, fenpropatrin, fenvalerate, flucitrinate, fluvalinate, etofenprox, silafluofen, tralomethrin, cycloprothrin, acrinatrine, bifenthrin, hull Fenprox, Praretrin, Frethrin, Flumethrin, Terraretin, Natural pyrethrin, Flamethrin, Resmethrin, Phenothrin, Cyphenothrin, Empentrin, Tetramethrin, Transfluthrin,
Imiprotoline and the like and isomers thereof. Carbamate compounds such as propoxer, isoprocarb, fenobucarb, xylylcarb, metolcarb, XMC,
Ethiophene carb, carbaryl, pirimicarb, bendiocarb, carbofuran, furatiocarb, carbosulfan, aminosulfuran, mesomil, phenoxycarb, alanicarb, cloetocarb, benfracarb, phenothiocarb and the like. Organic phosphorus compounds, for example,
Fenitrothion, fenthion, propaphos, cyanophos, prothiophos, sulfophos, propenophos,
EPN, cyanofenphos, acephate, oxydeprophos, disulfoton, thiomethone, fentoate,
Bamidione, mecarbam, trichlorfon, nail, dichlorobos, chlorfenvinphos, tetrachlorvinphos, monocrotophos, hosalon, diariphos,
Chlorpyrifos, chlorpyrifosmethyl, pirimiphosethyl, diazinon, etrimphos, pyridafenthion, quinalphos, isoxathion, methidathion, dioxabenzophos, pyraclophos, chlorthiophos, fortress, isofenphos, butathiophos, dichlorvos, methamidophos, propetanephos, phosthiazate,
Terbufos, ethione, temefos, malathion, fentoate, dimethoate, fermothion, azinphosethyl, azinphosmethyl, methidathion, etoprophos, pyraclofos and the like. Urea compounds, for example, diflubenzuron, chlorfluazuron, lufenuron, hexaflumuron, flufenoxuron, diafenthiuron, hexithiaxox, novanuron, teflubenzuron, triflumuron and the like. Cartap, thiocyclam, buprofezin, bensultap, thiacloprid, nitenpyram, acetamiprid, neonicotinoids such as diacloden, methoprene, hydroprene, fenazaquin, clofentezine, levamisole, genochlor, cyromazine, fenpyroximate, pyridaben,
Pyriproxyfen, sulfuramide, hydramethylnon, thiodicarb, chlorfenapyr, fenproximate, deafenthiuron, pymetrozine, pyridaben, pyrimidifen, tebufenozide, tebufenpyrad, triazamate, methoxadiazon, ethoxazole, phenylpyrazole and the like. Curane-3,4-diol, N, N-dimethyl-m-toluamide (DEET), p-menthane-3,8-diol (eucalidiodiol), 2,3,4,5
-Bis (△ 2-butylene) tetrahydrofurfural,
Di-n-propyl isosine coronate, di-n-butyl succinate, 2-hydroxyoctyl sulfide,
(N-carbosec-butyroxy) -2- (2′-hydroxyethyl) -piperidin, 3- (N-butyl-N-acetyl) -aminopropionate ethyl ester and the like.

[0011]

EXAMPLES Hereinafter, the present invention will be described in more detail with reference to examples, but the present invention is not limited to these examples.

Test Example 1 1% w / v dimethyl sulfoxide solutions of compound A and compound B were prepared. A predetermined amount of the drug was mixed with a potato dextrose agar medium immediately after sterilization (using a wet heat sterilizer), poured into a 9 cm diameter petri dish, and allowed to stand at room temperature. As a control, an agar medium to which only dimethyl sulfoxide was added was similarly prepared. After the medium was solidified, the mycelium was pulled out from the flora of Kawatake mushrooms that had been cultured in advance using a 5 mm-diameter cork borer together with the medium, and inoculated into the center of the test medium. Four days after the inoculation, the diameter of the flora that spread from the inoculation source was measured.
The growth inhibition rate of the bacteria compared with the diameter of the microflora in the control group was determined. Table 1 shows the results.

## EQU1 ## Growth inhibition rate (%) = {(diameter of microflora in control plot−diameter of microbiota in test plot) / diameter of microbiota in control plot} × 100

[0013]

[Table 1]

[0014]

The wood preservative of the present invention has an excellent wood preservative effect.

Claims (1)

[Claims] [Claim 1] Formula 1 And 4,6-dimethyl-2- (6-phenylpyridin-2-yl) pyrimidine represented by the formula: And N- (1,1,3-trimethyl-2-oxa-4-indanyl) -5-chloro-1,3-dimethylpyrazole-4-carboxylic acid amide as an active ingredient. Wood preservatives.