JP2000245764A - Thalamic system cooling device and using method of cooling body - Google Patents

Abstract

PROBLEM TO BE SOLVED: To efficiently cool a thalamic system for a short time by directly cooling the thalamic system not from an outside of a head part but from an inside thereof by improving the natural function of an organism for preventing the excess temperature rise of the thalamic system in a brain by respiration. SOLUTION: A thalamic system cooling device comprises a cooling body 1 included in an oral cavity, a circulating device for supplying a cooling medium to the cooling body 1 and recovering the cooling medium having circulated inside of the cooling body 1, and a temperature controller for controlling a temperature of the cooling medium. The cooling body 1 comprises an oral holding part 10 capable of flowing the cooling medium inside thereof. The oral holding part 10 has a size to be included in the oral cavity 40, and its upper surface side 101 is formed corresponding to the shape of a palate part 41. A communicating tube for guiding the cooling medium is mounted on a front part of the oral holding part 10.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a thalamic cooling system and a method of using a cooling body. More specifically,
By strengthening the natural function of the living body, which prevents excessive heating of the thalamus system in the brain due to respiration, the thalamus system is cooled directly from the inside rather than from the outside of the head. It relates to a device that can be cooled efficiently in a long time.

[0002]

2. Description of the Related Art In the field of medicine, for example, sinusitis,
It is common for brain temperature to rise above physiological (normal) values when various diseases such as cerebral dysfunction, stroke, brain tumor, head and neck trauma, and traumatic cervical syndrome occur. Are known. Excessive temperature rise in the brain causes biological enzyme reactions and inflammatory products to act, and further, for example, cerebral edema,
Serious secondary disorders such as elevated cerebral pressure and melting of brain organs (melting, necrosis) can be caused, and in some cases, death can result.

The inventor of the present invention has conducted studies in view of such a situation, and has developed a head and neck cooling device disclosed in Japanese Patent No. 2876399 as a means for preventing a secondary injury due to an excessive rise in temperature of the brain. It has been completed.

In this head and neck cooling device, the head and neck are covered with a cooling device main body, a cooling medium whose temperature is controlled is fed to the cooling device main body, and a cooling medium from the frontal region to the occipital region and the back and neck region is supplied. Only the area is partially cooled.

According to the head and neck cooling device, the entire brain is cooled from the outside of the head and neck to prevent an excessive rise in the temperature of the brain during cerebral dysfunction, during or after surgery, for example. Secondary obstacles can be prevented.

[0006] In recent years, if an excessive rise in temperature of at least the thalamus system (upper thalamus, lower thalamus, anterior thalamus, posterior thalamus, etc.) of the brain can be prevented, the above-mentioned secondary obstacles will be insufficient. Various studies have shown that it can be prevented. The reason for this is unclear, but it is thought that the thalamus system is the higher center of the autonomic nervous system consisting of a large number of nuclei and plays a role in automatically regulating the botanical functions of living organisms.
As a matter of course, a device for mainly cooling the thalamus system has not been developed.

[0007] The thalamus system is located in the lower part of the brain, that is, substantially at the center of the head, and is located at a position adjacent to the nasal cavity through the cavernous sinus surrounding the thalamus (see FIG. 4). .
The cavernous sinus is an aggregate of a myriad of capillaries, through which arteries that send blood to the brain and veins that return blood from the brain pass through. This cavernous sinus
The blood flow temperature in the capillaries is lowered by air inhaled through the nasal cavity by breathing, and the blood in the capillaries whose temperature has been lowered further lowers the temperature of the above-mentioned arteries and veins and the thalamus surrounding them. And has a function of performing heat exchange. That is, the temperature of the thalamus system is prevented from rising above a physiological value by air inhaled through the nasal cavity by respiration in a state without disease.

[0008]

Based on the results of the recent research described above, the head and neck cooling apparatus has the following problems. That is, since the head and neck cooling device cools the whole brain from outside the head and neck, it takes a considerable time to lower the temperature of the thalamus system located below the brain. For this reason, the head and neck cooling device cannot effectively prevent a secondary injury particularly for a disease requiring urgent cooling of the thalamus system, and it cannot be said that a fatal situation is not caused.
It should be noted that the head and neck cooling device can still be effectively used when long-term treatment is required.

[0009] The present invention solves the above-mentioned problems, and enhances the intrinsic function of a living body to prevent excessive increase in the temperature of the thalamus system in the brain due to respiration. It is an object of the present invention to provide a method of using a thalamic system cooling device and a cooling body that can cool the thalamic system directly from the side, so that it can be efficiently cooled in a short time.

[0010]

Means of the present invention taken to achieve the above object are as follows. In the first invention, a cooling body for cooling the oral cavity,
A cooling body formed in a shape that can be included in the oral cavity and provided with means for cooling the oral cavity and the nasal cavity.

According to a second aspect of the present invention, a cooling body for cooling the inside of the oral cavity is formed in a hollow shape that can be included in the oral cavity, and a cooling medium is introduced into the hollow portion. A cooling body characterized by comprising a deriving means.

According to a third aspect of the present invention, there is provided a cooling body according to the first or second aspect of the present invention, which has a deformability capable of deforming substantially along the shape of the palate.

According to a fourth aspect of the present invention, there is provided a thalamus system cooling device, comprising: a cooling body according to the first, second or third aspect;
And a temperature control device that controls the temperature of the cooling body.

According to a fifth aspect of the present invention, there is provided a thalamus cooling device, wherein the cooling device is formed in a hollow shape that can be included in an oral cavity, and a means for introducing a cooling medium into the hollow portion and leading it out. A cooling body having deformability that can be deformed substantially along the shape of the palate portion, a circulating device for circulating the cooling medium through a hollow portion of the cooling body, and the cooling body And a temperature control device for controlling the temperature of the thalamus.

According to a sixth aspect of the present invention, in order to cool the oral cavity and the nasal cavity, the surface temperature of the cooling body formed into a shape that can be included in the oral cavity is used. How to use the cooling body.

(Operation) The cooling body is formed in a shape that can be contained in the oral cavity, and is provided with a means for cooling the oral cavity and the nasal cavity. The air in the nasal cavity can be forcibly cooled by cooling the inside of the oral cavity and the nasal cavity with a cooling means. By inhaling the cooled air in the nasal cavity by respiration, the blood flow temperature in the capillaries constituting the cavernous sinus can be cooled more than usual. Then, the cooled blood in the cavernous sinus can cool the temperature of the thalamus system and the blood flow temperature of arteries and veins connected to the brain.

The cooling body which is formed in a hollow shape which can be contained in the oral cavity and which is provided with a means for introducing a cooling medium into the hollow portion and leading it out, includes the cooling medium in the oral cavity and comprises a cooling medium. Is introduced into the hollow portion and led out, heat exchange is performed in the oral cavity and the nasal cavity, and the air in the nasal cavity can be forcibly cooled. By inhaling the cooled air in the nasal cavity by respiration, the blood flow temperature in the capillaries constituting the cavernous sinus can be cooled more than usual. Then, the cooled blood in the cavernous sinus can cool the temperature of the thalamus system and the blood flow temperature of arteries and veins connected to the brain.

As described above, the cooling body cools the thalamus system by enhancing the intrinsic function of the living body that prevents an excessive rise in temperature due to respiration, so that the thalamus system can be directly cooled. Therefore, the cooling efficiency is better than that of a head and neck cooling device that cools the entire brain from outside the head and neck, and thereby the thalamus system can be efficiently cooled in a short time. Therefore, especially for diseases that require urgent cooling of the thalamus,
It is expected that effective prevention of secondary obstacles can be achieved.

The one having a deformability that can be deformed so as to substantially conform to the shape of the palate can reduce the loss of cooling efficiency when cooling the palate from inside the oral cavity.

A thalamic cooling device having a temperature control device for controlling the temperature of the cooling body can adjust the temperature in the oral cavity to be cooled. This prevents the temperature in the oral cavity from being too cold and causing frostbite, and conversely prevents the temperature from increasing and the cooling effect from being poor, and sets the temperature in the oral cavity to be cooled to a suitable temperature in advance. be able to.

The cooling body is contained in the oral cavity as described above,
The air in the nasal cavity is forcibly cooled by cooling the oral cavity and the nasal cavity. However, it is cooled in the mouth, nasal cavity,
Not only the cavernous sinus and the thalamus system, but also the vicinity can be naturally cooled. Thus, the thalamic system cooling device, in addition to cooling the temperature of the thalamic system to prevent secondary disorders, for example, glaucoma and cataract in ophthalmic diseases, in nasal diseases,
Sinusitis (pyometra), oral diseases include periodontitis, gingivitis, alveolar pyorrhea, and collagen diseases that are thought to be due to immunodeficiency, rheumatism, which is a motor organ pain disease. It may be effective for treatment (difficult depending on the type of disease) and prevention.

[0022]

DESCRIPTION OF THE PREFERRED EMBODIMENTS The present invention will be described in more detail with reference to the embodiments shown in the drawings. FIG. 1 is a schematic explanatory view showing an embodiment of a thalamus cooling device according to the present invention, FIG. 2 is a perspective explanatory view showing a cooling body, and FIG. 3 is an explanatory view showing a cross section of the cooling body shown in FIG. . Reference symbol S indicates a thalamus cooling device. The thalamus cooling device S is a cooling device 1 included in the oral cavity.
And a circulating device 2 that supplies a cooling medium (water in the present embodiment) to the cooling body 1 and collects the cooling medium after it is circulated therein, and a temperature control device that controls the temperature of the cooling medium. It has.

The cooling body 1 is provided with a mouth portion 10 formed in a hollow shape so as to have a heat exchange portion 100 through which a cooling medium can flow. The mouth portion 10 is formed in a size that can be contained in the oral cavity. In addition, mouth part 1
Reference numeral 0 denotes a transparent body having a required deformability, which is deformed when included in the oral cavity, and is formed such that the upper surface side 101 adheres substantially along the shape of the palate. Mouth part 1
On the lower surface of 0, there is formed a concave portion 102 in which the tongue is contained when contained in the oral cavity. As a material for forming the mouth portion 10, for example, a synthetic resin, a synthetic rubber, a natural rubber, or the like is used, but is not limited thereto. Further, it is not limited to a transparent body. Further, as long as the shape is such that it substantially adheres to the palate portion when contained in the oral cavity, it may be formed of a hard material having no deformability. Mouth part 1
The shape of 0 is not limited to the illustrated one, and may be formed to match the shape of the oral cavity including the tooth shape of the patient, for example.

Two communicating pipes 1 for introducing a cooling medium to the heat exchange section 100 and leading it out are provided at the front of the mouth section 10.
1, 12 are provided penetrating watertight. The inner end 111 of the communication pipe 11, which is the inlet side of the cooling medium, is extended so as to be located near the rear side of the heat exchange unit 100.
In addition, the inner end port 1 of the communication pipe 12 on the outlet side of the cooling medium.
Reference numeral 21 is located near the front side of the heat exchange unit 100. Outside the communication tubes 11 and 12, stoppers 110 and 12 for fixing a supply tube 22 (described later) to the communication tube 11 and a collection tube 23 (described later) to the communication tube 12.
0 is provided.

The circulation device 2 includes a pump 20 and a pressure gauge 21,
A supply tube 22 and a collection tube 23 are provided. Since these are publicly known, detailed description of the structure is omitted. The pump 20 is provided with a supply port 200 for supplying the cooling medium and a recovery port 201 for recovering the medium. One end of the feed tube 22 is connected to the feed port 200. The other end of the feed tube 22 is connected to the communication tube 11.
Is inserted into the outer end of the cover so as to cover the outer peripheral surface, and is fixed by a stopper 110 in a watertight manner. Further, one end of the collection tube 23 is connected to the collection port 201. The other end of the collection tube 23 is inserted into the outer end opening of the communication tube 12 so as to cover this outer peripheral surface.
Is fixed watertight. A pressure gauge 21 for measuring the pressure of the cooling medium during feeding is provided near the feeding port 200. The output state of the pump 20 can be visually recognized by the pressure gauge 21.

The temperature control device includes a heat exchange device 30, temperature sensors 31, 31, and the like. Since these are also known, detailed description of the structure is omitted. The heat exchange device 30 is provided so as to be able to cool the cooling medium stored in the pump 20.
The position where the heat exchange device 30 is provided is not limited to the inside of the pump 20. The temperature sensors 31, 31 are provided at required positions of the feeding tube 22 and the collecting tube 23, respectively.

In the present embodiment, water is used as the cooling medium as described above. However, the cooling medium is not limited to this as long as it has fluidity, and may be, for example, a lower alcohol. Further, it may be liquid or gas.

(Operation) FIG. 4 is an explanatory diagram showing a use state of the thalamic cooling system shown in the present embodiment. The operation of the embodiment of the present invention will be described with reference to FIGS.
A method of using the thalamus cooling device S will be described. First,
The cooling body 1 is included in the oral cavity 40 of the patient, and the upper surface side 101 of the mouth-containing portion 10 is deformed so as to substantially adhere to the palate portion 41. Then, the pump 20 is operated to supply the cooling medium to the supply tube 22.

The cooling medium supplied to the supply tube 22 is introduced into the heat exchange section 100 through the communication pipe 11.
At this time, the inner end port 111 of the communication pipe 11
Since the cooling medium is located near the rear side, the introduced cooling medium strikes the rear wall in the heat exchange unit 100 and diffuses.

When the cooling medium is introduced into the heat exchanging section 100, the upper surface 101 of the mouth section 10 is substantially in close contact with the palate section 41, so that the cooling medium removes the heat of the palate section 41. An attempted heat exchange takes place. Thereby, the palate 41 is cooled. In addition, this allows the cooling medium to pass through the palate 41
, And the temperature is higher than when the heat is introduced into the heat exchange unit 100.

Since the cooling medium is arranged such that the inner end port 121 of the communication pipe 12 is located near the front side of the heat exchange section 100, the cooling medium does not stay in the heat exchange section 100 and smoothly. It is derived from the communication pipe 12. Therefore, the cooling medium whose temperature has increased due to heat exchange with the palate portion 41 can be immediately discharged, and the efficiency of heat exchange is high.

The cooling medium led out of the communication pipe 12 is
It is collected again by the pump 20 through the collection tube 23. That is, the cooling medium is circulated by the pump 20.

The temperature of the cooling medium is managed by a temperature controller. More specifically, the temperature of the cooling medium flowing through the supply tube 22 and the collection tube 23 is measured by the temperature sensors 31, 31, and the temperature of the palate portion 41 when cooled is suitable according to the temperature difference. So, cooling body 1
Is controlled so that the temperature of the cooling medium fed to the heat exchanger is adjusted by the heat exchange device 30. However, the method of controlling the temperature of the cooling medium by the temperature control device is not limited to this.
The temperature of the palate 41 when it is cooled depends on the type of the disease, but there is a risk of causing frostbite at 0 ° C or less, and the cooling effect becomes poor at a high temperature. For example, it is generally considered safe if the temperature is in the range of 2 to 10 ° C., and it is more preferable to set the temperature in the range of 2 to 5 ° C. However, this does not limit the temperature of the palate 41 when cooled.

When the palate 41 is cooled as described above, heat exchange is performed between the palate 41 and the nasal cavity 42 next. That is, the air in the nasal cavity 42 is forcibly cooled by the palate 41. By sucking the cooled air in the nasal cavity 42 by respiration, the blood flow temperature in the capillaries constituting the cavernous sinus 43 can be cooled more than usual. The cooled blood in the cavernous sinus 43 can cool the temperature of the thalamus system 44 and the blood flow temperature of arteries and veins connected to the brain.

As described above, the thalamic system cooling device S cools the thalamic system by strengthening the intrinsic function of the living body that prevents an excessive rise in temperature due to respiration, so that the thalamic system 44 can be directly cooled. it can. Therefore, the cooling efficiency is better than that of a head and neck cooling device that cools the entire brain from outside the head and neck, and thus the thalamus system 44 can be efficiently cooled in a short time. Therefore, it can be expected that secondary disorders can be effectively prevented, especially for diseases requiring urgent cooling of the thalamus system 44.

The mouth portion 10 has a required deformability,
Since the palate 41 is substantially adhered to the palate 41 when contained in the oral cavity 40, loss of cooling efficiency when the palate 41 is cooled from within the oral cavity 40 can be reduced.

As described above, the thalamus system cooling device S includes the mouth portion 10 of the cooling body 1 in the oral cavity 40, cools the oral cavity 40 and the nasal cavity 42, and forcibly releases the air in the nasal cavity 42. It is designed to cool down. However, it is possible to cool not only the oral cavity, the intranasal cavity, the cavernous sinus, and the thalamus system, but also the vicinity thereof. This allows the thalamic system cooling device to take away the heat of the thalamic system 44 to prevent secondary disorders, such as glaucoma and cataract in ophthalmic diseases,
For rhinitis, sinusitis (pyometra), for oral diseases, periodontitis, gingivitis, alveolar pyorrhea, and for collagen diseases that are thought to be caused by immunodeficiency, rheumatism, a motor organ pain disease, It may be effective for treatment (difficult depending on the type of disease) and prevention of various diseases such as.

In the present embodiment, the heat exchange with the palate is performed by the cooling medium fed to the cooling body. However, the means for exchanging heat with the palate is not particularly limited to the cooling medium. Absent. Further, the configuration of the thalamic cooling device according to the present invention is not limited to the thalamic cooling device S described in the present embodiment.

The terms and expressions used in the present specification are illustrative only, and are not restrictive. Terms and expressions equivalent to the features described in this specification and some of them are not limited thereto. There is no intention to exclude expression. It goes without saying that various modifications are possible within the scope of the technical idea of the present invention.

[0040]

The present invention has the above configuration and has the following effects. (A) Since the cooling body is formed in a shape that can be included in the oral cavity and includes a means for cooling the oral cavity and the nasal cavity, the cooling body is included in the oral cavity and a means for cooling the oral cavity and the nasal cavity The air in the nasal cavity can be forcibly cooled by cooling the oral cavity and the nasal cavity. By inhaling the cooled air in the nasal cavity by respiration, the blood flow temperature in the capillaries constituting the cavernous sinus can be cooled more than usual. Then, the cooled blood in the cavernous sinus can cool the temperature of the thalamus system and the blood flow temperature of arteries and veins connected to the brain.

(B) The cooling body is formed in a hollow shape that can be contained in the oral cavity, and is provided with a means for introducing a cooling medium into the hollow portion and leading it out. By introducing the cooling medium into the hollow portion and extracting it, heat exchange is performed in the oral cavity and the nasal cavity, and the air in the nasal cavity can be forcibly cooled. By inhaling the cooled air in the nasal cavity by respiration, the blood flow temperature in the capillaries constituting the cavernous sinus can be cooled more than usual. And, by the blood of the cooled cavernous sinus,
The temperature of the thalamus system and the blood flow temperature of arteries and veins leading to the brain can be cooled.

(C) As described above, the cooling body enhances the intrinsic function of the living body for preventing an excessive rise in temperature due to respiration, and cools the thalamus system, so that the thalamus system can be directly cooled. . Therefore, the cooling efficiency is better than that of a head and neck cooling device that cools the entire brain from the outside of the head and neck, whereby the thalamus system can be efficiently cooled in a short time. Therefore, it can be expected that secondary disorders can be effectively prevented, especially for diseases requiring urgent cooling of the thalamus system.

(D) When the palate is cooled from the inside of the oral cavity, a loss in cooling efficiency can be reduced if the palate is deformable so as to substantially conform to the shape of the palate.

(E) The thalamic cooling device having a temperature control device for controlling the temperature of the cooling body can adjust the temperature in the oral cavity to be cooled. This prevents the temperature in the oral cavity from being too cold and causing frostbite, and conversely prevents the temperature from increasing and the cooling effect from being poor, and sets the temperature in the oral cavity to be cooled to a suitable temperature in advance. be able to.

(F) The cooling body is contained in the oral cavity as described above, and cools the oral cavity and the nasal cavity to forcibly cool the air in the nasal cavity. However, it is possible to cool not only the oral cavity, the intranasal cavity, the cavernous sinus, and the thalamus system, but also the vicinity thereof. This allows the thalamic system cooling device to cool the thalamic system to prevent secondary disorders. For example, glaucoma and cataract for ophthalmic diseases, sinusitis (pyometra) for nasal diseases, and oral systems Treatment of various diseases such as periodontitis, gingivitis, alveolar pyorrhea, and rheumatism, which is a musculoskeletal pain disease in collagen diseases thought to be caused by immunodeficiency (difficult depending on the type of disease) And prevention may be effective.

[Brief description of the drawings]

FIG. 1 is a schematic explanatory view showing one embodiment of a thalamus cooling device according to the present invention.

FIG. 2 is a perspective explanatory view showing a cooling body.

FIG. 3 is an explanatory diagram showing a cross section of the cooling body shown in FIG. 2;

FIG. 4 is an explanatory diagram showing a usage state of the thalamic cooling device shown in the present embodiment.

[Explanation of symbols]

 S Thalamic System Cooling Device 1 Cooling Body 10 Including Port 100 Heat Exchange Unit 101 Upper Side 102 Concave 11 Communication Tube 110 Stopper 111 Inner End 12 Communication Tube 120 Stopper 121 Inner End 2 Circulating Device 20 Pump 200 Feeding Port Reference Signs List 201 collection port 21 pressure gauge 22 feeding tube 23 collection tube 30 heat exchange device 31 temperature sensor 40 oral cavity 41 palate 42 nasal cavity 43 cavernous sinus 44 thalamus system

Claims (6)

[Claims] 1. A cooling body for cooling the inside of an oral cavity, wherein the cooling body is formed in a shape that can be included in the oral cavity, and has a means for cooling the inside of the oral cavity and the nasal cavity. , Cooling body. 2. A cooling body for cooling the inside of the oral cavity, the cooling body being formed in a hollow shape that can be included in the oral cavity, and having a means for introducing a cooling medium into the hollow portion and leading it out. A cooling body. 3. The cooling body according to claim 1, wherein the cooling body has a deformability capable of deforming substantially along the shape of the palate portion. 4. A thalamus cooling device, comprising: the cooling body according to claim 1, 2, or 3; and a temperature control device that controls a temperature of the cooling body. System cooling device. 5. A cooling device for a thalamus system, wherein the cooling device is formed in a hollow shape that can be included in an oral cavity, and is provided with means for introducing a cooling medium into the hollow portion and leading it out. A cooling body having a deformability capable of deforming so as to substantially follow, a circulating device for circulating the cooling medium through a hollow portion of the cooling body, and a temperature control for controlling a temperature of the cooling body. And a device, comprising: a thalamic cooling device. 6. A method for using a cooling body, characterized in that a cooling body formed into a shape that can be included in the oral cavity is used at a reduced surface temperature in order to cool the oral cavity and the nasal cavity.