JP2000239107A - Low-smelling acaricide - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain a suitably usable acaricide capable of eliminating a nasty smell and an unpleasant chemical smell, emitting a preferable aroma by formulating benzyl alcohol with phenylethyl alcohol. SOLUTION: This acaricide comprises (A) benzyl alcohol and (B) phenylethyl alcohol as active ingredients. Preferably, 10 pts.wt. of the component A is formulated with 3-70 pts.wt. of the component B. The acaricide can be formulated with a natural essential oil component having acaricidal properties in such a degree as not to cause a nasty smell and a problem of smell strength. The acaricide is especially suitable in a state of a control-release formulation making the best use of transpiration. Consequently, the acaricide does not have a nasty smell and an unpleasant chemical smell which are produced in the case of using the component A alone, emits a preferable aroma and favorably used. The acaricide is transpirable and can effectively treat a wide surface in contact with space.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

TECHNICAL FIELD The present invention relates to a tick controlling agent,
More specifically, the present invention relates to an agent for controlling mites, which is highly transpirable and highly safe for the human body, has an excellent control effect on indoor dust mites, and is particularly characterized by low odor.

[0002]

2. Description of the Related Art In recent years, breeding of house mites, particularly house dust mites, which are often present in house dust, causing allergic diseases has become a problem in ordinary households. Various insecticides are effective against blood-sucking mites, but most of these insecticides are not effective against mites that cause allergic diseases as described above. Group "19
Written in March 1995, "Allergy and living environment".

[0003] Slightly organophosphorus compounds, carbamate compounds and pyrethroid compounds are known as acaricides, some of which are used in Europe and the United States, and pyrethroid compounds are also used in Japan.

Also, studies on acaricides with low toxicity to the human body have been actively conducted, and those using plant essential oils derived from natural products have been reported as being highly safe and capable of controlling mites widely. (JP-A-63-104905). The above-mentioned plant essential oil is used to control indoor ticks by evaporating, and evaporative components are applied in various dosage forms in the fields of fragrance and sterilization. In particular, in recent years, with the spread of aromatherapy, attention has been paid to aromatic substances mainly composed of natural essential oil components.

[0005] However, when a natural essential oil component having an acaricide action is used in a living space, it has an unpleasant odor,
There is a problem that it is unpleasant because the smell is too strong.

[0006]

DISCLOSURE OF THE INVENTION The present invention has been made to solve the above-mentioned problems and to provide an acaricide which can reduce the odor generated when a transpirable natural essential oil component having an excellent acaricidal effect is used. The purpose is to do.

[0007]

DISCLOSURE OF THE INVENTION The present inventors have found benzyl alcohol as a substance having particularly high acaricidal and low odor properties from natural essential oil components having acaricidal activity and its main components. However, benzyl alcohol alone emits an unpleasant chemical odor, although it has low odor.Therefore, benzylethyl alcohol is used as a fragrance that has high acaricidal activity, although not as high as benzyl alcohol, and is generally easy to taste. The present invention has been found to be able to generate not only an unpleasant odor and an unpleasant chemical odor, but also to generate a preferable fragrance by blending it with alcohol, thereby completing the present invention.

[0008] The low-odor mite control agent according to claim 1 is characterized by comprising benzyl alcohol and phenylethyl alcohol as active ingredients.

The low-odor mite control agent according to claim 2 is the mite control agent according to claim 1, wherein phenylethyl alcohol is added to 10 parts by weight of benzyl alcohol.
It is characterized by containing up to 70 parts by weight.

[0010] Benzyl alcohol and phenylethyl alcohol are highly safe compounds that are also blended as fragrances in cosmetics and the like.

The mixing ratio of benzyl alcohol and phenylethyl alcohol is 70% if phenylethyl alcohol is 3 parts by weight or more with respect to 10 parts by weight of benzyl alcohol, without causing discomfort due to the chemical odor of benzyl alcohol. When the amount is less than the weight part, the problem that the odor due to phenylethyl alcohol becomes too strong and unpleasant is also solved.

The acaricide of the present invention includes a natural essential oil component having acaricidal activity or a component purified as a single component from the natural essential oil, in addition to the above-mentioned components, in terms of off-flavor and odor intensity. It can be blended in a range that is not necessary.

The natural essential oil components having acaricidal properties include:
Mint oil, cassia oil, almond bitter oil, columnum oil, peppermint oil, spearmint oil, cinnamon oil, allspice oil, clove oil, thyme oil, rosemary oil, lemongrass oil, lemon oil, yuzu oil, lime oil, apple aroma Oil, grapefruit oil, sweet orange oil, navel oil, sweetie oil, Valencia orange oil, mandarin oil, bergamot oil, laurel oil, star anise oil,
Sweet fennel oil, marjoram oil, mace oil, boad rose oil, palmarosa oil, lemon verbena oil, lemon balm oil, lavender oil, rose oil, eucalyptus oil, tea tree oil, ylang ylang oil, vetiver oil, pachiyouri oil, cananga oil, kagetput oil , Citronella oil, nutmeg oil, pepper oil, sandalwood oil, bulk oil,
Carzine oil, ginger oil, campo oil, cucumber oil, corn mint oil, anise oil, lang oil, cinnamon oil, mace oil, paromarosa oil, fennel oil, thyme oil, neem oil, laurel oil, laurel oil, sword oil, etc. No.

Further, those purified as a single component from these natural essential oils may be used. For example, menthol, mentone, limonene, citral, citronellal, citronellol, geraniol, cinnamaldehyde, eugenol, anethole, α-pinene, β-pinene, 2-phenoxyethanol and the like can be mentioned.

The low-odor mites controlling agent of the present invention may contain various fungicides, fungicides, insect repellents, preservatives, deodorants, and coloring agents. Benzalkonium chloride as a fungicide,
Benzethonium chloride, alkyltrimethylammonium chloride, resorcinol, phenol, sorbic acid, salicylic acid, hexachlorophene, 2,4,4 '
-Trichloro-2'-hydroxydiphenyl ether and the like, which are effective for controlling fungi such as Aspergillus, Penicillium, Ketomium and the like.

Examples of the insect repellent include N, N-diethyl-meta-toluamide, 2,3,4,5-bis (d2-butylene) -tetrahydrofural and lemongrass. Examples include methacrylate and various flavonoids. Preservatives include methyl p-oxybenzoate and ethyl p-oxybenzoate, and coloring agents include Red No. 2, Blue No. 1, Red No. 202, and Red 201.
Dyes, green dye No. 204, purple dye No. 201, etc., aluminum powder, and inorganic dyes such as talc, kaolin, bentonite, mica, titanium, red iron and calamine.

Although the above-mentioned active ingredient can be applied to the low-odor mite controlling agent of the present invention as it is, usually, the active ingredient is held in a liquid or solid carrier, and if necessary, a solvent, an emulsifier, a dispersant, By using bases, propellants and sustained-release agents, oils, emulsions, wettable powders, sprays (aerosols), sustained-release agents (liquid, powdery, granular), smokers, heat-evaporants, etc. It is also possible to use in the form of.

The propellants include Freon 11, Freon 12, Freon 21, Freon 22, Freon 113, Freon 114,
Methyl chloride, isobutane, carbon dioxide, liquefied petroleum gas, dimethyl ether and the like are used.

Among the forms of the mite control agent, the form of a sustained release agent utilizing transpiration is particularly suitable. Sustained-release preparations generally hold a transpirant acaricidal substance dispersed or impregnated in a liquid or solid carrier.

Among the above-mentioned carriers impregnated with the acaricidal substance,
The liquid carrier may be any as long as it can disperse the acaricidal substance as a liquid, for example, ethyl alcohol as a solvent,
Alcohols such as isopropyl alcohol, acetone,
Ketones such as methyl ethyl ketone, ethers such as THF, dioxane, and diethyl ether; aliphatic hydrocarbons such as normal paraffin and solvent naphtha; aromatic hydrocarbons such as benzene and toluene; dichloroethane;
Or as a solvent soaps, polyoxyethylene fatty acid alcohol ether, polyoxyethylene fatty acid ester,
It is adjusted by mixing and stirring an acaricidal substance with a surfactant such as polyoxyethylene alkyl allyl ether, fatty acid glyceide, sorbitan fatty acid ester, higher alcohol sulfate, and alkyl allyl sulfonic acid.

In the case of a solid carrier, any material may be used as long as it has a gap and a large surface area for holding the acaricide and other compounds according to the present invention. The material may be a synthetic resin sheet such as polypropylene, animal or plant material or inorganic material. A single or mixed fibrous sheet (paper, cloth, nonwoven fabric, leather, etc.) is used. The form of the carrier is preferably a blended fabric, a nonwoven fabric using long fibers or short fibers, or the like.

In order to impregnate the carrier with the mite control agent,
Mineral spirits, mineral terpenes, solvent naphtha, terpene oils, various alcohols, ethers and water may be used as solvents and dispersants.

Also, sustained release is achieved by loading on a sublimable carrier such as tricyclodecane, cyclododecane, 2,4,6-triisopropyl-1,3,5-trioxane, trimethylnorbornene, paradichlorobenzene, naphthalene or camphor. Sex can also be adjusted.

The mites targeted by the low-odor mite control agent of the present invention are the arthropod-Arachnida-Acari organisms,
Divided into three sub-areas. That is, the back respiratory tract represented by the red ticks, the four reticulate typified by the ticks, the stomach ticks represented by the ticks, the red stomach represented by the swallow chick mite, the mid stomach represented by the house dust mite, the stag beetle, the stag beetle,
The primordial stomach typified by the mites Dermatophagoids
It is an esoteric gate typified by Dermatophagoides farinae, an esoteric gate typified by a house dust mite, and a mites mite. Although any of the above types can be a target, the main targets are Dermatophagoides and Dermatophagoides, which are particularly abundant in bedding and cause allergic diseases.

The place where the low odor mite control agent of the present invention is used includes a closed space having a certain ventilation rate, for example, a clothes box, a dresser, a closet, an entrance space, a clog box and the like.

(Action) The low-odor mite controlling agent of the present invention comprises benzyl alcohol having high acaricidal and low-odor properties, and phenylethyl alcohol, which is generally tasting rose and acaricidal, and comprises phenylethyl alcohol. Therefore, an unpleasant odor and an unpleasant chemical odor due to benzyl alcohol can be eliminated, and a preferable fragrance can be generated by phenylethyl alcohol and used suitably. Further, since the above-mentioned components are transpirable, a wide surface in contact with the space can be effectively treated.

Further, when the mixing ratio of benzyl alcohol and phenylethyl alcohol is in the range of 3 to 70 parts by weight of phenylethyl alcohol with respect to 10 parts by weight of benzyl alcohol, the above-mentioned effect is more remarkably exhibited.

[0028]

Embodiments of the present invention will be described below. In addition, parts means parts by weight. (Example 1, Comparative Examples 1 to 5) Natural essential oil components shown in Table 1 were used to examine the acaricidal effect and the degree of odor.

(Examples 2 to 6) In order to examine the relationship between the mixing ratio of benzyl alcohol and phenylethyl alcohol and the odor, the components shown in Table 2 were used.

Performance evaluation Test mite: Dermatophagoides pter
onyssinus) ♀ Adult (1) Acaricidal effect Evaluated by the acaricidal rate after exposure for 1 week at a concentration of 1 ppm of a natural essential oil component. Preparation of Test Mite Container A glass microfiber filter paper having a diameter of 70 mm was folded in two, and two sides were clipped to form a bag, and selected from the test tick culture medium. Thirty individuals were charged from the opening of the filter paper bag, and 10 mg of a mixture of mouse feed and dry yeast mixed at a ratio of 1: 1 was charged from above, and the opening was clipped to obtain a test mite container. Preparation of Experimental Container A petri dish containing 30 ml of a saturated saline solution for humidity adjustment was placed in a polypropylene container having an inner volume of 100 liters, and three bags of the test mite containers prepared in the above were placed on another petri dish and placed in a separate petri dish. Placed inside the container. Installation of mite control agent When each natural essential oil component shown in Table 1 was evaporated in a 100-liter container, the concentration was measured to be 1 ppm, and the filter was impregnated into glass filter paper. Place it on a polyethylene table half the height of the container,
The container was covered with a lid made of polyethylene, and sealed tightly with waterproof tape without any gap. Counting of the number of mites After one week, the test mite container was taken out, air-dried in clean air for one hour, allowed to stand at 25 ° C. and 75% RH for 18 hours, then the filter paper was opened and the mites were examined with a stereoscopic microscope. Was confirmed life and death. In order to confirm whether the operation of the experiment affected the test mites, a test mite container for control was prepared at the same time as the test mite container used for the experiment, and stored in a test container not using natural essential oil. And

Judgment of Effect Using the average value of the mite survival rate in each test plot (X ₁ ) and the average value of the tick survival rate in the control plot (X ₀ ), the corrected mortality (Y ) Was calculated, and the results are shown in Table 1. Y (%) = {(X ₀ −X ₁ ) / X ₀ } × 100 The result was the average value of three test mite containers.

(2) Evaluation of odor A mixture of benzyl alcohol and phenylethyl alcohol having the compounding ratio shown in Table 2 was used. The impregnated carrier with the above-mentioned natural essential oil component was placed in a closet of a general household, and evaluated by a questionnaire result by a sensory test. Preparation of a carrier impregnated with a natural essential oil component Kraft paper (6 cm x 6 cm, thickness 2 mm, basis weight 0.
1 g / cm ² ) was impregnated with 2 g of a natural essential oil component shown in Table 2 and fixed in a polypropylene container (vent area: 70%) having vent holes. The natural essential oil component impregnated carriers prepared by the sensory test method were placed in the center of the upper surface of the inside of the closet in each of five ordinary households, and the results of a normal life for one week including raising and lowering of the futon were questionnaire surveyed. The obtained answers were totaled based on the scores shown in Table 1, and evaluated based on the total score of each natural essential oil component (a total score of 0 or more was regarded as a satisfactory level).

[0033]

[Table 1]

The acaricidal effect is shown in Table 2, and the odor evaluation results are shown in Tables 2 and 3. FIG. 1 shows the relationship between the mixing ratio of benzyl alcohol and phenylethyl alcohol and the odor intensity.

[0035]

[Table 2]

[0036]

[Table 3]

[0037]

EFFECT OF THE INVENTION Since the low odor mite controlling agent of the present invention has the above constitution, it is possible to reduce the odor and unpleasant chemical odor generated when benzyl alcohol is used for controlling ticks, Alcohol produces a preferable aroma and can be used suitably. Further, since the above-mentioned components are transpirable, a wide surface in contact with the space can be effectively treated. Further, the mixing ratio of benzyl alcohol and phenylethyl alcohol was set such that phenylethyl alcohol was added to 10 parts by weight of benzyl alcohol.
A higher effect can be obtained by setting the content to 70 parts by weight.

[Brief description of the drawings]

FIG. 1 is an explanatory diagram showing the relationship between the mixing ratio of benzyl alcohol and phenylethyl alcohol and the odor intensity.

 ────────────────────────────────────────────────── ─── Continued on the front page (72) Inventor Satoshi Tamaki 2-1 Momoyama, Shimamoto-cho, Mishima-gun, Osaka Prefecture Sekisui Chemical Co., Ltd. F-term (reference) 4H011 AC04 BA06 BB03 BB22 DA02 DA14 DA15 DA16 DA21 DG03

Claims (2)

[Claims] 1. A mite control agent comprising benzyl alcohol and phenylethyl alcohol as active ingredients. 2. The mite control agent according to claim 1, wherein the composition contains 3 to 70 parts by weight of phenylethyl alcohol per 10 parts by weight of benzyl alcohol.