JOP20240245A1 - التركيبات الصيدلانية لـ glp1 - Google Patents

التركيبات الصيدلانية لـ glp1

Info

Publication number
JOP20240245A1
JOP20240245A1 JOJO/P/2024/0245A JOP20240245A JOP20240245A1 JO P20240245 A1 JOP20240245 A1 JO P20240245A1 JO P20240245 A JOP20240245 A JO P20240245A JO P20240245 A1 JOP20240245 A1 JO P20240245A1
Authority
JO
Jordan
Prior art keywords
glp1
pharmaceutical formulations
fluoro
methylpropylcyclo
oxoimidazol
Prior art date
Application number
JOJO/P/2024/0245A
Other languages
Arabic (ar)
English (en)
Inventor
Lee Joseph Burns
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of JOP20240245A1 publication Critical patent/JOP20240245A1/ar

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/485Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4866Organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
JOJO/P/2024/0245A 2022-05-11 2024-11-05 التركيبات الصيدلانية لـ glp1 JOP20240245A1 (ar)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202263340591P 2022-05-11 2022-05-11
PCT/US2023/021637 WO2023220109A1 (en) 2022-05-11 2023-05-10 Glp1 pharmaceutical compositions

Publications (1)

Publication Number Publication Date
JOP20240245A1 true JOP20240245A1 (ar) 2024-11-05

Family

ID=86732348

Family Applications (1)

Application Number Title Priority Date Filing Date
JOJO/P/2024/0245A JOP20240245A1 (ar) 2022-05-11 2024-11-05 التركيبات الصيدلانية لـ glp1

Country Status (17)

Country Link
US (1) US20250302809A1 (https=)
EP (1) EP4522129A1 (https=)
JP (2) JP7767651B2 (https=)
KR (1) KR20250002778A (https=)
CN (1) CN119173255A (https=)
AR (1) AR129296A1 (https=)
AU (1) AU2023269995A1 (https=)
CA (1) CA3253043A1 (https=)
CL (1) CL2024003392A1 (https=)
CO (1) CO2024015285A2 (https=)
DO (1) DOP2024000232A (https=)
IL (1) IL316629A (https=)
JO (1) JOP20240245A1 (https=)
MX (1) MX2024013839A (https=)
PE (2) PE20260136A1 (https=)
TW (2) TW202508581A (https=)
WO (1) WO2023220109A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4522131A1 (en) * 2022-05-11 2025-03-19 Eli Lilly and Company Glp1 tablet compositions
CN120981457A (zh) 2023-09-14 2025-11-18 歌礼制药(中国)有限公司 Glp-1r激动剂及其治疗方法
TW202540124A (zh) * 2023-11-21 2025-10-16 大陸商江蘇恆瑞醫藥股份有限公司 雜環類化合物、其製備方法及其在醫藥上的應用
TW202521534A (zh) 2023-11-24 2025-06-01 香港商歌禮製藥(中國)有限公司 Glp-1r 激動劑及其治療方法
TW202600132A (zh) 2024-03-08 2026-01-01 美商安尼波那生物公司 用於治療肥胖症及提高減重之方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2434641A1 (en) * 2001-01-18 2002-08-22 Pharmacia And Upjohn Company Chemotherapeutic microemulsion compositions of paclitaxel with improved oral bioavailability
US7115565B2 (en) * 2001-01-18 2006-10-03 Pharmacia & Upjohn Company Chemotherapeutic microemulsion compositions of paclitaxel with improved oral bioavailability
WO2008030524A2 (en) * 2006-09-08 2008-03-13 Merck & Co., Inc. Liquid pharmaceutical formulations for oral administration of a cgrp antagonist
JOP20190060A1 (ar) * 2016-09-26 2019-03-26 Chugai Pharmaceutical Co Ltd مشتق بيرازولو بيريدين له تأثير مساعد لمستقبل glp-1
JP7461104B2 (ja) 2017-11-29 2024-04-03 中外製薬株式会社 Glp-1受容体アゴニスト作用を持つピラゾロピリジン誘導体を含有する医薬組成物
US20220023266A1 (en) 2018-12-07 2022-01-27 Neurocrine Biosciences, Inc. Crf1 receptor antagonist, pharmaceutical formulations and solid forms thereof for the treatment of congenital adrenal hyperplasia
US11884672B2 (en) 2019-05-14 2024-01-30 Vertex Pharmaceuticals Incorporated Modulators of alpha-1 antitrypsin
CA3191084A1 (en) 2020-09-09 2022-03-17 Gerald Burke Formulations of a somatostatin modulator
EP4522131A1 (en) 2022-05-11 2025-03-19 Eli Lilly and Company Glp1 tablet compositions

Also Published As

Publication number Publication date
MX2024013839A (es) 2024-12-06
CA3253043A1 (en) 2023-11-16
CN119173255A (zh) 2024-12-20
CL2024003392A1 (es) 2025-03-14
AR129296A1 (es) 2024-08-07
JP2025515706A (ja) 2025-05-20
PE20251285A1 (es) 2025-05-14
JP7767651B2 (ja) 2025-11-11
JP2026021422A (ja) 2026-02-10
EP4522129A1 (en) 2025-03-19
PE20260136A1 (es) 2026-01-21
IL316629A (en) 2024-12-01
DOP2024000232A (es) 2024-12-30
KR20250002778A (ko) 2025-01-07
US20250302809A1 (en) 2025-10-02
CO2024015285A2 (es) 2024-11-28
WO2023220109A1 (en) 2023-11-16
AU2023269995A1 (en) 2024-11-14
TW202410894A (zh) 2024-03-16
TW202508581A (zh) 2025-03-01
TWI867526B (zh) 2024-12-21

Similar Documents

Publication Publication Date Title
JOP20240245A1 (ar) التركيبات الصيدلانية لـ glp1
Ellepola et al. Oral candidal infections and antimycotics
NO972968D0 (no) Fremgangsmåte, sammensetninger og sett for öking av oral biotilgjengelighet av farmasöytiske midler
WO2023205463A8 (en) Heteroaryl compounds for the treatment of pain
AR050838A1 (es) Formulacion farmaceutica. para el tratamiento de una infeccion optica
PL361341A1 (pl) Nowa kompozycja farmaceutyczna
EE05103B1 (et) Famatseutilised kompositsioonid, mis sisaldavad asetidiini derivaate, asetidiini derivaadid ja nende valmistamise meetodid
IL159843A0 (en) Amino-phthalazinone derivatives active as kinase inhibitors, process for their preparation and pharmaceutical compositions containing them
PE20020853A1 (es) Composiciones farmaceuticas, formas de dosificacion y metodos para la administracion oral de epotilonas
MA53927B1 (fr) Composition pharmaceutique pour une administration par voie orale comprenant un dérivé d'aminopyrimidine ou son sel
ES2826884T3 (es) Combinación de un compuesto de pirroloquinolina y un agente antimicrobiano betalactámico, mupirocina o clorhexidina
GEAP202516634A (en) Heteroaryl compounds for the treatment of pain
EP1365749A4 (en) PROCESS FOR PREPARING PHARMACEUTICAL COMPOSITIONS FOR USE WITH WEICHGELATINE FORMULATIONS
MXPA05009719A (es) Derivados de biciclo-pirazol activos como inhibidores de cinasa, procedimiento para su preparacion y composiciones farmaceuticas que los comprenden.
ATE298324T1 (de) Deuterierte 3-piperidinopropiophenone sowie diese verbindungen enthaltende arzneimittel
HUP0402577A2 (hu) Citoszol foszfolipáz A2 inhibitor hatású indolszármazékok, eljárás előállításukra
CR20240480A (es) Composiciones de comprimidos de glp1
TW200509992A (en) Dosage form containing pantoprazole as active ingredient
Ellepola et al. Antimycotic agents in oral candidosis: an overview: 2. Treatment of oral candidosis
MA26788A1 (fr) COMPOSITIONS PHARMACEUTIQUES DESTINÉES à L'ADMINISTRATION PAR VOIE ORALE DE PHLOROGLUCINOL ET LEUR PRÉPARATION
ZA202301927B (en) Phytonadione compositions
ATE395043T1 (de) Amoxycillin und clavulanat enthaltende pharmazeutische brausefromulierung
NO20054360L (no) Nye oxazolderivater, deres fremstilling og anvendelse som farmasotiske preparater
WO2025186786A8 (en) Oral pharmaceutical composition of pitavastatin and ezetimibe, method and uses thereof
EA200400691A1 (ru) Получение чистых стереоизомеров трицикло[5,2,1,02,6]дец-9-ил-ксантогената и содержащие их лекарственные средства