JO3418B1 - عملية اقتران خاصة ب pnag وبروتين حامل - Google Patents

عملية اقتران خاصة ب pnag وبروتين حامل

Info

Publication number
JO3418B1
JO3418B1 JOP/2007/0087A JOP20070087A JO3418B1 JO 3418 B1 JO3418 B1 JO 3418B1 JO P20070087 A JOP20070087 A JO P20070087A JO 3418 B1 JO3418 B1 JO 3418B1
Authority
JO
Jordan
Prior art keywords
pnag
carrier protein
activated
conjugation process
linker
Prior art date
Application number
JOP/2007/0087A
Other languages
English (en)
Inventor
Maira-Litran Tomas
Leon Biemans Ralph
Duvivier Pierre
Original Assignee
Glaxosmithkline Biologicals Sa
Brigham & Womens Hospital Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43217117&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JO3418(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB0606417A external-priority patent/GB0606417D0/en
Priority claimed from GB0606416A external-priority patent/GB0606416D0/en
Application filed by Glaxosmithkline Biologicals Sa, Brigham & Womens Hospital Inc filed Critical Glaxosmithkline Biologicals Sa
Application granted granted Critical
Publication of JO3418B1 publication Critical patent/JO3418B1/ar

Links

Landscapes

  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)

Abstract

<strong><span dir="RTL">يتعلق طلب الاختراع الحالي بعملية إقران، لإقران (</span></strong>PNAG<strong><span dir="RTL">) والذي يكون قد تمت أستيللته بنسبة أقل من 40% -</span></strong>N<strong><span dir="RTL">- (عند ذرة النيتروجين)، وذلك مع بروتين حامل، حيث تشتمل هذه العملية على: (أ) تنشيط ال </span></strong>PANG<strong><span dir="RTL"> بواسطة اضافة مادة رابطة تشتمل على مجموعة "ماليميد" لتكوين </span></strong>(PANG)<strong><span dir="RTL"> منشطة وفعال، </span></strong> <strong><span dir="RTL"> (ب) تنشيط البروتين الحامل بواسطة إضافة مادة رابطة تشتمل على مجموعة "سلفيدرايل" لتكوين بروتين حامل منشط وفعال، (ج) إجراء تفاعل ال </span></strong>(PANG)<strong><span dir="RTL"> النشط الفعال مع البروتين الحامل المنشط والفعال لتكوين متقارن البروتين الحامل لل </span></strong>(PANG)<strong><span dir="RTL">.</span></strong>
JOP/2007/0087A 2006-03-30 2007-03-28 عملية اقتران خاصة ب pnag وبروتين حامل JO3418B1 (ar)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US78758706P 2006-03-30 2006-03-30
US78724906P 2006-03-30 2006-03-30
GB0606417A GB0606417D0 (en) 2006-03-30 2006-03-30 Immunogenic composition
GB0606416A GB0606416D0 (en) 2006-03-30 2006-03-30 Immunogenic composition

Publications (1)

Publication Number Publication Date
JO3418B1 true JO3418B1 (ar) 2019-10-20

Family

ID=43217117

Family Applications (2)

Application Number Title Priority Date Filing Date
JOP/2007/0087A JO3418B1 (ar) 2006-03-30 2007-03-28 عملية اقتران خاصة ب pnag وبروتين حامل
JOP/2007/0092A JO3420B1 (ar) 2006-03-30 2007-03-28 تركيبة صيدلانية ولقاح للوقاية من اصابات المكورة العقدية

Family Applications After (1)

Application Number Title Priority Date Filing Date
JOP/2007/0092A JO3420B1 (ar) 2006-03-30 2007-03-28 تركيبة صيدلانية ولقاح للوقاية من اصابات المكورة العقدية

Country Status (4)

Country Link
CL (1) CL2007000839A1 (ar)
JO (2) JO3418B1 (ar)
PE (3) PE20120262A1 (ar)
TW (1) TWI494124B (ar)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102120761B (zh) * 2010-12-24 2013-02-06 新疆维吾尔自治区畜牧科学院兽医研究所 一种无荚膜型金黄色葡萄球菌胞外多糖-蛋白质偶联物的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE459373T1 (de) * 1999-03-19 2010-03-15 Glaxosmithkline Biolog Sa Impfstoff gegen kapsulare polysaccharide von streptococcus pneumoniae
CA2517439C (en) * 2003-03-07 2013-07-23 Wyeth Holdings Corporation Polysaccharide - staphylococcal surface adhesin carrier protein conjugates for immunization against nosocomial infections
EP1638601B1 (en) * 2003-06-23 2008-11-19 Baxter International Inc. Carrier proteins for vaccines

Also Published As

Publication number Publication date
JO3420B1 (ar) 2019-10-20
TWI494124B (zh) 2015-08-01
CL2007000839A1 (es) 2008-01-25
TW200806314A (en) 2008-02-01
PE20120262A1 (es) 2012-03-30
PE20080774A1 (es) 2008-08-08
PE20080129A1 (es) 2008-04-08

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