ITRM20030485A1 - Composizione a base di citicolina in associazione con vitamine per la prevenzione ed il trattamento di patolgie oculari. - Google Patents
Composizione a base di citicolina in associazione con vitamine per la prevenzione ed il trattamento di patolgie oculari.Info
- Publication number
- ITRM20030485A1 ITRM20030485A1 IT000485A ITRM20030485A ITRM20030485A1 IT RM20030485 A1 ITRM20030485 A1 IT RM20030485A1 IT 000485 A IT000485 A IT 000485A IT RM20030485 A ITRM20030485 A IT RM20030485A IT RM20030485 A1 ITRM20030485 A1 IT RM20030485A1
- Authority
- IT
- Italy
- Prior art keywords
- citicoline
- eye
- composition based
- patolgies
- vitamins
- Prior art date
Links
- 229960001284 citicoline Drugs 0.000 title abstract 2
- 229930003231 vitamin Natural products 0.000 title abstract 2
- 235000013343 vitamin Nutrition 0.000 title abstract 2
- 239000011782 vitamin Substances 0.000 title abstract 2
- 229940088594 vitamin Drugs 0.000 title abstract 2
- RZZPDXZPRHQOCG-OJAKKHQRSA-N CDP-choline Chemical compound O[C@@H]1[C@H](O)[C@@H](COP(O)(=O)OP([O-])(=O)OCC[N+](C)(C)C)O[C@H]1N1C(=O)N=C(N)C=C1 RZZPDXZPRHQOCG-OJAKKHQRSA-N 0.000 title 1
- 230000002265 prevention Effects 0.000 title 1
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 abstract 2
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 abstract 2
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 abstract 1
- RZZPDXZPRHQOCG-OJAKKHQRSA-M CDP-choline(1-) Chemical compound O[C@@H]1[C@H](O)[C@@H](COP([O-])(=O)OP([O-])(=O)OCC[N+](C)(C)C)O[C@H]1N1C(=O)N=C(N)C=C1 RZZPDXZPRHQOCG-OJAKKHQRSA-M 0.000 abstract 1
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 abstract 1
- 208000010412 Glaucoma Diseases 0.000 abstract 1
- FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 abstract 1
- 229930003268 Vitamin C Natural products 0.000 abstract 1
- 229930003427 Vitamin E Natural products 0.000 abstract 1
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 abstract 1
- OEYIOHPDSNJKLS-UHFFFAOYSA-N choline Chemical compound C[N+](C)(C)CCO OEYIOHPDSNJKLS-UHFFFAOYSA-N 0.000 abstract 1
- 229960001231 choline Drugs 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000003412 degenerative effect Effects 0.000 abstract 1
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 abstract 1
- 235000016709 nutrition Nutrition 0.000 abstract 1
- 230000007170 pathology Effects 0.000 abstract 1
- 235000019155 vitamin A Nutrition 0.000 abstract 1
- 239000011719 vitamin A Substances 0.000 abstract 1
- 235000019154 vitamin C Nutrition 0.000 abstract 1
- 239000011718 vitamin C Substances 0.000 abstract 1
- 235000019165 vitamin E Nutrition 0.000 abstract 1
- 229940046009 vitamin E Drugs 0.000 abstract 1
- 239000011709 vitamin E Substances 0.000 abstract 1
- 229940045997 vitamin a Drugs 0.000 abstract 1
- 150000003722 vitamin derivatives Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4415—Pyridoxine, i.e. Vitamin B6
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/15—Vitamins
- A23L33/155—Vitamins A or D
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/07—Retinol compounds, e.g. vitamin A
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
- A61K31/355—Tocopherols, e.g. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- Nutrition Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Priority Applications (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT000485A ITRM20030485A1 (it) | 2003-10-22 | 2003-10-22 | Composizione a base di citicolina in associazione con vitamine per la prevenzione ed il trattamento di patolgie oculari. |
| PCT/IT2004/000565 WO2005037262A1 (en) | 2003-10-22 | 2004-10-14 | Citicoline-based composition in combination with vitamins for the prevention and treatment of eye pathologies |
| EP04791899A EP1677774B1 (en) | 2003-10-22 | 2004-10-14 | Citicoline-based composition in combination with vitamins for the prevention and treatment of eye pathologies |
| ES04791899T ES2360221T3 (es) | 2003-10-22 | 2004-10-14 | Composición basada en citicolina en combinación con vitaminas para la prevención y el tratamiento de patologías del ojo. |
| AT04791899T ATE499093T1 (de) | 2003-10-22 | 2004-10-14 | Zusammensetzung auf citicolin-basis in kombination mit vitaminen zur prävention und behandlung von augenerkrankungen |
| DE602004031540T DE602004031540D1 (de) | 2003-10-22 | 2004-10-14 | Zusammensetzung auf citicolin-basis in kombination mit vitaminen zur prävention und behandlung von augenerkrankungen |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT000485A ITRM20030485A1 (it) | 2003-10-22 | 2003-10-22 | Composizione a base di citicolina in associazione con vitamine per la prevenzione ed il trattamento di patolgie oculari. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ITRM20030485A0 ITRM20030485A0 (it) | 2003-10-22 |
| ITRM20030485A1 true ITRM20030485A1 (it) | 2005-04-23 |
Family
ID=30131627
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT000485A ITRM20030485A1 (it) | 2003-10-22 | 2003-10-22 | Composizione a base di citicolina in associazione con vitamine per la prevenzione ed il trattamento di patolgie oculari. |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP1677774B1 (it) |
| AT (1) | ATE499093T1 (it) |
| DE (1) | DE602004031540D1 (it) |
| ES (1) | ES2360221T3 (it) |
| IT (1) | ITRM20030485A1 (it) |
| WO (1) | WO2005037262A1 (it) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007045407A2 (en) * | 2005-10-18 | 2007-04-26 | Artmed S.R.L. | Nutraceutical and pharmaceutical compositions containing choline as adiuvants for the prevention and treatment of retinopathies and glaucoma |
| WO2007059762A1 (de) * | 2005-11-25 | 2007-05-31 | Gisela Susilo | Kombinationspräparate enthaltend physiologische zellmembran-bestandteile, einschliesslich phosphatidylserin, cholin und ein pyrimidinnukleos/tid |
| AU2010328186B2 (en) | 2009-12-08 | 2014-12-18 | Case Western Reserve University | Compounds and methods of treating ocular disorders |
| ITMI20121223A1 (it) * | 2012-07-13 | 2014-01-14 | Gregorio Fabio De | Nuova composizione farmacologica comprendente citicolina in combinazione con glicerolo e/o acetazolamide |
| WO2020106746A1 (en) | 2018-11-19 | 2020-05-28 | Heh Research & Development Services, Inc. | Biologic enhancement formulation |
| CN111840220B (zh) * | 2020-08-19 | 2022-09-30 | 开封康诺药业有限公司 | 一种胞磷胆碱钠注射液及其制备方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2280093A1 (en) * | 1997-02-04 | 1998-08-06 | John V. Kosbab | Compositions and methods for prevention and treatment of vascular degenerative diseases |
| TW580397B (en) * | 1997-05-27 | 2004-03-21 | Takeda Chemical Industries Ltd | Solid preparation |
| US6740339B1 (en) * | 1999-06-18 | 2004-05-25 | Takeda Chemical Industries, Ltd. | Quickly disintegrating solid preparations |
| EP1329217A4 (en) * | 2000-10-06 | 2007-04-04 | Takeda Pharmaceutical | SOLID PREPARATIONS |
| US6506412B2 (en) * | 2000-11-29 | 2003-01-14 | Sciencebased Health | Treatment of dry eye syndrome |
| US6583152B2 (en) * | 2001-04-30 | 2003-06-24 | Dexgen Pharmaceuticals, Inc. | Composition for reducing the risk or progression of cardiovascular diseases |
-
2003
- 2003-10-22 IT IT000485A patent/ITRM20030485A1/it unknown
-
2004
- 2004-10-14 EP EP04791899A patent/EP1677774B1/en active Active
- 2004-10-14 DE DE602004031540T patent/DE602004031540D1/de active Active
- 2004-10-14 WO PCT/IT2004/000565 patent/WO2005037262A1/en active Search and Examination
- 2004-10-14 ES ES04791899T patent/ES2360221T3/es active Active
- 2004-10-14 AT AT04791899T patent/ATE499093T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ATE499093T1 (de) | 2011-03-15 |
| WO2005037262A1 (en) | 2005-04-28 |
| DE602004031540D1 (de) | 2011-04-07 |
| ITRM20030485A0 (it) | 2003-10-22 |
| EP1677774B1 (en) | 2011-02-23 |
| EP1677774A1 (en) | 2006-07-12 |
| ES2360221T3 (es) | 2011-06-02 |
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