ITRM20010336A0 - Anticorpo umano ricombinante diretto contro la proteina non strutturale ns3 del virus dell'epatite c (hcv), acido nucleico codificante e usi - Google Patents

Anticorpo umano ricombinante diretto contro la proteina non strutturale ns3 del virus dell'epatite c (hcv), acido nucleico codificante e usi

Info

Publication number
ITRM20010336A0
ITRM20010336A0 IT2001RM000336A ITRM20010336A ITRM20010336A0 IT RM20010336 A0 ITRM20010336 A0 IT RM20010336A0 IT 2001RM000336 A IT2001RM000336 A IT 2001RM000336A IT RM20010336 A ITRM20010336 A IT RM20010336A IT RM20010336 A0 ITRM20010336 A0 IT RM20010336A0
Authority
IT
Italy
Prior art keywords
hcv
hepatitis
virus
protein
structural
Prior art date
Application number
IT2001RM000336A
Other languages
English (en)
Inventor
Roberto Burioni
Massimo Clementi
Original Assignee
Biostrands S R L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biostrands S R L filed Critical Biostrands S R L
Priority to IT2001RM000336A priority Critical patent/ITRM20010336A1/it
Publication of ITRM20010336A0 publication Critical patent/ITRM20010336A0/it
Priority to PCT/IT2002/000384 priority patent/WO2002100900A2/en
Priority to AU2002317474A priority patent/AU2002317474A1/en
Priority to DE60232155T priority patent/DE60232155D1/de
Priority to EP02745784A priority patent/EP1417233B1/en
Priority to AT02745784T priority patent/ATE430167T1/de
Priority to DK02745784T priority patent/DK1417233T3/da
Priority to US10/480,843 priority patent/US7314919B2/en
Publication of ITRM20010336A1 publication Critical patent/ITRM20010336A1/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1081Togaviridae, e.g. flavivirus, rubella virus, hog cholera virus
    • C07K16/109Hepatitis C virus; Hepatitis G virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55Fab or Fab'
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00Uses of viruses
    • C12N2799/02Uses of viruses as vector
    • C12N2799/021Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/028Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a herpesvirus

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
IT2001RM000336A 2001-06-13 2001-06-13 Anticorpo umano ricombinante diretto contro la proteina non strutturale ns3 del virus dell'epatite c (hcv), acido nucleico codificante e usi ITRM20010336A1 (it)

Priority Applications (8)

Application Number Priority Date Filing Date Title
IT2001RM000336A ITRM20010336A1 (it) 2001-06-13 2001-06-13 Anticorpo umano ricombinante diretto contro la proteina non strutturale ns3 del virus dell'epatite c (hcv), acido nucleico codificante e usi
PCT/IT2002/000384 WO2002100900A2 (en) 2001-06-13 2002-06-11 Human recombinant antibody against the hepatitis c (hcv) non structural ns3 protein, nucleic acid and uses thereof
AU2002317474A AU2002317474A1 (en) 2001-06-13 2002-06-11 Human recombinant antibody against the hepatitis c (hcv) non structural ns3 protein, nucleic acid and uses thereof
DE60232155T DE60232155D1 (de) 2001-06-13 2002-06-11 Humaner rekombinanter antikörper gegen das hepatitis c (hcv) nichtstrukturelles ns3 protein, nukleinsäure und deren verwendungen
EP02745784A EP1417233B1 (en) 2001-06-13 2002-06-11 Human recombinant antibody against the hepatitis c (hcv) non structural ns3 protein, nucleic acid and uses thereof
AT02745784T ATE430167T1 (de) 2001-06-13 2002-06-11 Humaner rekombinanter antikörper gegen das hepatitis c (hcv) nichtstrukturelles ns3 protein, nukleinsäure und deren verwendungen
DK02745784T DK1417233T3 (da) 2001-06-13 2002-06-11 Humant rekombinant antistof mod det hepatitis C (HCV) ikke-strukturelle NS3-protein, nukleinsyre og anvendelser deraf
US10/480,843 US7314919B2 (en) 2001-06-13 2002-06-11 Human recombinant antibody against the hepatitis C (HCV) non structural NS3 protein nucleic acid and uses thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT2001RM000336A ITRM20010336A1 (it) 2001-06-13 2001-06-13 Anticorpo umano ricombinante diretto contro la proteina non strutturale ns3 del virus dell'epatite c (hcv), acido nucleico codificante e usi

Publications (2)

Publication Number Publication Date
ITRM20010336A0 true ITRM20010336A0 (it) 2001-06-13
ITRM20010336A1 ITRM20010336A1 (it) 2002-12-13

Family

ID=11455593

Family Applications (1)

Application Number Title Priority Date Filing Date
IT2001RM000336A ITRM20010336A1 (it) 2001-06-13 2001-06-13 Anticorpo umano ricombinante diretto contro la proteina non strutturale ns3 del virus dell'epatite c (hcv), acido nucleico codificante e usi

Country Status (8)

Country Link
US (1) US7314919B2 (it)
EP (1) EP1417233B1 (it)
AT (1) ATE430167T1 (it)
AU (1) AU2002317474A1 (it)
DE (1) DE60232155D1 (it)
DK (1) DK1417233T3 (it)
IT (1) ITRM20010336A1 (it)
WO (1) WO2002100900A2 (it)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE448866T1 (de) * 2003-02-19 2009-12-15 Natrix Separations Inc Geträgerte poröse gele umfassende verbundmaterialien
DE602006012836D1 (de) * 2005-06-02 2010-04-22 Akira Matsumori Verfahren zur sichtung von anti-hepatits c virus kandidaten
US7705138B2 (en) * 2005-11-11 2010-04-27 Vertex Pharmaceuticals Incorporated Hepatitis C virus variants
EP2392590A3 (en) 2005-11-11 2012-03-14 Vertex Pharmaceuticals Incorporated Hepatitis C virus variants
US7858752B2 (en) * 2006-12-05 2010-12-28 Abbott Laboratories Recombinant antibodies against hepatitis C virus and methods of obtaining and using same
ES2456961T3 (es) 2007-02-21 2014-04-24 University Of Massachusetts Anticuerpos humanos contra el virus de la hepatitis C (VHC), usos de los mismos
ATE550350T1 (de) 2009-07-10 2012-04-15 Univ Berlin Freie Rock2 und rock3, zwei neue gain-of-function- varianten der cytokininrezeptoren ahk2 und ahk3

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6194140B1 (en) * 1990-04-04 2001-02-27 Chiron Corporation HCV NS3 protein fragments having helicase activity and improved solubility
DE60043708D1 (de) * 1999-10-13 2010-03-04 Novartis Vaccines & Diagnostic Verfahren zur erhaltung zellimmuneantworten gegen proteinen

Also Published As

Publication number Publication date
WO2002100900A3 (en) 2004-03-04
ATE430167T1 (de) 2009-05-15
EP1417233A2 (en) 2004-05-12
AU2002317474A1 (en) 2002-12-23
WO2002100900A2 (en) 2002-12-19
US20040214994A1 (en) 2004-10-28
DE60232155D1 (de) 2009-06-10
US7314919B2 (en) 2008-01-01
ITRM20010336A1 (it) 2002-12-13
EP1417233B1 (en) 2009-04-29
DK1417233T3 (da) 2009-06-29

Similar Documents

Publication Publication Date Title
ATE277945T1 (de) Makrozyklische peptide als hepatitis c virus ns3 protease inhibitore
PT1090033E (pt) Particulas de proteinas de envelope do hcv: utilizacao para vacinacao
ATE405647T1 (de) Rekombinantes gelatin in impstoffen
IT1278077B1 (it) Metodologia per riprodurre in vitro le attivita' di rna polimerasi rna-dipendente e di nucleotidiltransferasi terminale codificate dal
HK1092498A1 (en) Composition containing the polyprotein ns3/ns4 and the polypeptide ns5b of hcv, expression vectors comprising corresponding nucleic sequences and the therapeutic application thereof
WO2004085633A8 (en) A novel human virus causing severe acute respiratory syndrome (sars) and uses thereof
WO2004076619A3 (en) New dengue and west nile viruses proteins and genes coding the foregoing, and their use in vaccinal, therapeutic and diagnostic applications
BR0108499A (pt) Agente terapêutico para hepatite c
WO2001021807A8 (en) Hepatitis c virus envelope two protein (e2) which lacks all or part of the hypervariable region one (hvr1), corresponding nucleic acids, chimeric viruses and uses thereof
AU2001290178A1 (en) A hepatitis c virus non-structural ns3/4a fusion gene
WO2003004627A3 (fr) Lignees d'hepatomes humains leurs optentions et leurs applications
ITRM20010336A0 (it) Anticorpo umano ricombinante diretto contro la proteina non strutturale ns3 del virus dell'epatite c (hcv), acido nucleico codificante e usi
DE60232862D1 (de) Rekombinantes pockenvirus für chimäre proteine des menschlichen immunschwächevirus
HK1062579A1 (en) A fusion protein for treatment of hepatitis b virus and its use thereof
EP1613345A4 (en) COMPOSITIONS AND METHODS WITH THE RESPIRATORY SYNCYTIAL VIRUS SUB-GROUP B STAMM 9320
EP1141255A4 (en) MODIFIED FORMS OF HEPATITIS C VIRUS NS3 PROTEASE
DE60034884D1 (de) Klonierte genome von infektiösen hepatitis c viren genotyp 2a und deren verwendungen
IL161138A0 (en) Treatment of hepatitis b virus infection with human monoclonal antibodies
FR2825102B1 (fr) Nouveaux polynucleotides et polypeptides de l'interferon alpha 14
WO2004014936A3 (fr) Melange de peptides issus des proteines c et ns3 du virus de l'hepatite c et leurs applications.
FR2825716B1 (fr) Nouveaux polynucleotides et polypeptides de l'ifn alpha 7
EP1521849A4 (en) HEPATITIS A-VIRUS NUCLEOTIDE SEQUENCES, RECOMBINANT PROTEINS AND THEIR USE
IL151033A0 (en) Purified hepatitis c virus envelope proteins for diagnostic and therapeutic use
GB0215617D0 (en) Use of hepatitis C virus (HCV) p7 protein
RU2004104357A (ru) Вакцинный состав, потенцированный комбинацией днк и антигена