ITMI931175A1 - Polisaccaridi ad elevata attivita' antitrombotica e anticoagulante - Google Patents
Polisaccaridi ad elevata attivita' antitrombotica e anticoagulanteInfo
- Publication number
- ITMI931175A1 ITMI931175A1 IT93MI001175A ITMI931175A ITMI931175A1 IT MI931175 A1 ITMI931175 A1 IT MI931175A1 IT 93MI001175 A IT93MI001175 A IT 93MI001175A IT MI931175 A ITMI931175 A IT MI931175A IT MI931175 A1 ITMI931175 A1 IT MI931175A1
- Authority
- IT
- Italy
- Prior art keywords
- polyesaccharides
- thrombotic
- coagulant activity
- chains
- formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Materials Engineering (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Abstract
Polisaccaridi costituiti da catene o miscele di catene aventi un peso molecolare compreso fra circa 1000 e circa 100000 da o più, caratterizzati da una struttura disaccaridica ripetuta di formula I (FORMULA I) dove A, B, R, R1, R2, R3 e R4some come definiti nella descrizione, loro sali con cationi di metalli alcalini o alcalino terrosi, sono dotati di notevoli proprietà anticoagulanti e antitrombotiche.
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI931175A IT1270823B (it) | 1993-06-04 | 1993-06-04 | Polisaccaridi ad elevata attivita' antitrombotica e anticoagulante |
PCT/EP1994/001660 WO1994029352A1 (en) | 1993-06-04 | 1994-05-24 | Polysaccharides having high antithrombotic and anticoagulant activity |
AU68448/94A AU6844894A (en) | 1993-06-04 | 1994-05-24 | Polysaccharides having high antithrombotic and anticoagulant activity |
IL10988194A IL109881A0 (en) | 1993-06-04 | 1994-06-02 | Novel polysaccharides having high antithrombotic and anticoagulant activity |
ZA943868A ZA943868B (en) | 1993-06-04 | 1994-06-02 | Novel polysaccharides having high antithrombotic and anticoagulant activity |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI931175A IT1270823B (it) | 1993-06-04 | 1993-06-04 | Polisaccaridi ad elevata attivita' antitrombotica e anticoagulante |
Publications (3)
Publication Number | Publication Date |
---|---|
ITMI931175A0 ITMI931175A0 (it) | 1993-06-04 |
ITMI931175A1 true ITMI931175A1 (it) | 1994-12-04 |
IT1270823B IT1270823B (it) | 1997-05-13 |
Family
ID=11366330
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ITMI931175A IT1270823B (it) | 1993-06-04 | 1993-06-04 | Polisaccaridi ad elevata attivita' antitrombotica e anticoagulante |
Country Status (5)
Country | Link |
---|---|
AU (1) | AU6844894A (it) |
IL (1) | IL109881A0 (it) |
IT (1) | IT1270823B (it) |
WO (1) | WO1994029352A1 (it) |
ZA (1) | ZA943868B (it) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1284143B1 (it) * | 1996-09-06 | 1998-05-08 | Istituto Scient Di Chimica E B | Eparansolfati semi-sintetici ad elevata attivita' antimetastica e ridotto rischio emorragico |
AUPO556297A0 (en) * | 1997-03-11 | 1997-04-10 | Australian National University, The | Sulfated oligosaccharides having anticoagulant/ antithrombotic activity |
US6329351B1 (en) | 1997-08-28 | 2001-12-11 | Istituto Scientifico Di Chimica E Biochimica “G. Ronzoni” | Semi-synthetic sulphaminoheparosansulphates having high anti-metastatic activity and reduced haemorrhagic risk |
AUPO976897A0 (en) | 1997-10-14 | 1997-11-06 | Australian National University, The | Use of sulfated oligosaccharides in lowering blood triglyceride levels |
US6608042B2 (en) * | 2000-03-28 | 2003-08-19 | Aventis Pharma, S.A. | Pharmaceutical compositions containing oligosaccharides, the novel oligosaccharides and preparation thereof |
US20040171819A1 (en) | 2002-10-10 | 2004-09-02 | Aventis Pharma S.A. | Mixtures of polysaccharides derived from heparin, their preparation and pharmaceutical compositions containing them |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0209924A1 (en) * | 1985-07-12 | 1987-01-28 | Akzo N.V. | New anti-trombosis agent based on glycosaminoglycan, process for its preparation, and pharmaceutical compositions |
GB2254083A (en) * | 1991-03-28 | 1992-09-30 | Italfarmaco Spa | Anticoagulants from e.coli saccharide |
FR2684385B1 (fr) * | 1991-11-28 | 1997-08-01 | Sanofi Elf | Heparosanes-n,o-sulfates de haute masse moleculaire, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
-
1993
- 1993-06-04 IT ITMI931175A patent/IT1270823B/it active IP Right Grant
-
1994
- 1994-05-24 WO PCT/EP1994/001660 patent/WO1994029352A1/en active Application Filing
- 1994-05-24 AU AU68448/94A patent/AU6844894A/en not_active Abandoned
- 1994-06-02 IL IL10988194A patent/IL109881A0/xx unknown
- 1994-06-02 ZA ZA943868A patent/ZA943868B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
ITMI931175A0 (it) | 1993-06-04 |
AU6844894A (en) | 1995-01-03 |
WO1994029352A1 (en) | 1994-12-22 |
IL109881A0 (en) | 1994-10-07 |
IT1270823B (it) | 1997-05-13 |
ZA943868B (en) | 1995-02-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
0001 | Granted |