ITMI20120192A1 - Procedimento per la preparazione di un inibitore delle proteasi virali e suoi intermedi - Google Patents

Procedimento per la preparazione di un inibitore delle proteasi virali e suoi intermedi

Info

Publication number
ITMI20120192A1
ITMI20120192A1 IT000192A ITMI20120192A ITMI20120192A1 IT MI20120192 A1 ITMI20120192 A1 IT MI20120192A1 IT 000192 A IT000192 A IT 000192A IT MI20120192 A ITMI20120192 A IT MI20120192A IT MI20120192 A1 ITMI20120192 A1 IT MI20120192A1
Authority
IT
Italy
Prior art keywords
preparation
viral
inhibitor
proteasis
procedure
Prior art date
Application number
IT000192A
Other languages
English (en)
Inventor
Emanuele Attolino
Evita Balducci
Mario Michieletti
Maurizio Taddei
Original Assignee
Dipharma Francis Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dipharma Francis Srl filed Critical Dipharma Francis Srl
Priority to IT000192A priority Critical patent/ITMI20120192A1/it
Priority to PCT/EP2013/052819 priority patent/WO2013120871A1/en
Publication of ITMI20120192A1 publication Critical patent/ITMI20120192A1/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1024—Tetrapeptides with the first amino acid being heterocyclic
IT000192A 2012-02-13 2012-02-13 Procedimento per la preparazione di un inibitore delle proteasi virali e suoi intermedi ITMI20120192A1 (it)

Priority Applications (2)

Application Number Priority Date Filing Date Title
IT000192A ITMI20120192A1 (it) 2012-02-13 2012-02-13 Procedimento per la preparazione di un inibitore delle proteasi virali e suoi intermedi
PCT/EP2013/052819 WO2013120871A1 (en) 2012-02-13 2013-02-13 Process for the preparation of a viral protease inhibitor and its intermediates

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT000192A ITMI20120192A1 (it) 2012-02-13 2012-02-13 Procedimento per la preparazione di un inibitore delle proteasi virali e suoi intermedi

Publications (1)

Publication Number Publication Date
ITMI20120192A1 true ITMI20120192A1 (it) 2013-08-14

Family

ID=45998544

Family Applications (1)

Application Number Title Priority Date Filing Date
IT000192A ITMI20120192A1 (it) 2012-02-13 2012-02-13 Procedimento per la preparazione di un inibitore delle proteasi virali e suoi intermedi

Country Status (2)

Country Link
IT (1) ITMI20120192A1 (it)
WO (1) WO2013120871A1 (it)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014033667A1 (en) * 2012-08-30 2014-03-06 Ranbaxy Laboratories Limited Process for the preparation of telaprevir

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007022459A2 (en) * 2005-08-19 2007-02-22 Vertex Pharmaceuticals Incorporated Processes and intermediates
WO2010075064A1 (en) * 2008-12-16 2010-07-01 Sepracor Inc. Triple reuptake inhibitors and methods of their use

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SV2003000617A (es) 2000-08-31 2003-01-13 Lilly Co Eli Inhibidores de la proteasa peptidomimetica ref. x-14912m

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007022459A2 (en) * 2005-08-19 2007-02-22 Vertex Pharmaceuticals Incorporated Processes and intermediates
WO2010075064A1 (en) * 2008-12-16 2010-07-01 Sepracor Inc. Triple reuptake inhibitors and methods of their use

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DAVID R. WILLIAMS ET AL: "Strategies for the Synthesis of Fusicoccanes by Nazarov Reactions of Dolabelladienones: Total Synthesis of (+)-Fusicoauritone", ANGEWANDTE CHEMIE INTERNATIONAL EDITION, vol. 46, no. 6, 29 January 2007 (2007-01-29), pages 915 - 918, XP055032805, ISSN: 1433-7851, DOI: 10.1002/anie.200603853 *
PRASAD: "Synthesis of Hydroxyethylene Dipeptide Isosters That Mimic a Cyclic Amino Acid at the PI' Subsite", TETRAHEDRON LETTERS, vol. 32, no. 42, 1 January 1991 (1991-01-01), pages 5857 - 5860, XP055032916 *

Also Published As

Publication number Publication date
WO2013120871A1 (en) 2013-08-22

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