ITMI20051418A1 - ANALOGUES OF THIOILCYCOSIDE WITH HYDRO-LASER ACTIVITY AND ANTI-INFLAMMATORY - Google Patents

ANALOGUES OF THIOILCYCOSIDE WITH HYDRO-LASER ACTIVITY AND ANTI-INFLAMMATORY

Info

Publication number
ITMI20051418A1
ITMI20051418A1 IT001418A ITMI20051418A ITMI20051418A1 IT MI20051418 A1 ITMI20051418 A1 IT MI20051418A1 IT 001418 A IT001418 A IT 001418A IT MI20051418 A ITMI20051418 A IT MI20051418A IT MI20051418 A1 ITMI20051418 A1 IT MI20051418A1
Authority
IT
Italy
Prior art keywords
thioilcycoside
analogues
hydro
inflammatory
laser activity
Prior art date
Application number
IT001418A
Other languages
Italian (it)
Inventor
Ezio Bombardelli
Gabriele Fontana
Maria Luisa Gelmi
Paolo Morazzoni
Donato Pocar
Guido Pontremoli
Antonella Riva
Original Assignee
Indena Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Indena Spa filed Critical Indena Spa
Priority to IT001418A priority Critical patent/ITMI20051418A1/en
Priority to AU2006271923A priority patent/AU2006271923A1/en
Priority to CNA2006800267270A priority patent/CN101228175A/en
Priority to CA002615860A priority patent/CA2615860A1/en
Priority to MX2008000968A priority patent/MX2008000968A/en
Priority to EP06762703A priority patent/EP1907405A1/en
Priority to BRPI0613680-0A priority patent/BRPI0613680A2/en
Priority to NZ565265A priority patent/NZ565265A/en
Priority to JP2008521882A priority patent/JP2009502755A/en
Priority to PCT/EP2006/007108 priority patent/WO2007009772A1/en
Priority to RU2008102251/04A priority patent/RU2008102251A/en
Priority to KR1020087001654A priority patent/KR20080036585A/en
Publication of ITMI20051418A1 publication Critical patent/ITMI20051418A1/en
Priority to NO20080377A priority patent/NO20080377L/en
Priority to IL188900A priority patent/IL188900A0/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/24Condensed ring systems having three or more rings
    • C07H15/248Colchicine radicals, e.g. colchicosides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02Muscle relaxants, e.g. for tetanus or cramps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/39Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
    • C07C323/40Y being a hydrogen or a carbon atom
    • C07C323/41Y being a hydrogen or an acyclic carbon atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Epidemiology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
IT001418A 2005-07-22 2005-07-22 ANALOGUES OF THIOILCYCOSIDE WITH HYDRO-LASER ACTIVITY AND ANTI-INFLAMMATORY ITMI20051418A1 (en)

Priority Applications (14)

Application Number Priority Date Filing Date Title
IT001418A ITMI20051418A1 (en) 2005-07-22 2005-07-22 ANALOGUES OF THIOILCYCOSIDE WITH HYDRO-LASER ACTIVITY AND ANTI-INFLAMMATORY
NZ565265A NZ565265A (en) 2005-07-22 2006-07-20 Thiocolchicoside analogues with myorelaxant and anti-inflammatory activity
JP2008521882A JP2009502755A (en) 2005-07-22 2006-07-20 Thiocolchicoside analogues with muscle relaxant and anti-inflammatory effects
CA002615860A CA2615860A1 (en) 2005-07-22 2006-07-20 Thiocolchicoside analogues with myorelaxant and anti-inflammatory activity
MX2008000968A MX2008000968A (en) 2005-07-22 2006-07-20 Thiocolchicoside analogues with myorelaxant and anti-inflammatory activity.
EP06762703A EP1907405A1 (en) 2005-07-22 2006-07-20 Thiocolchicoside analogues with myorelaxant and anti-inflammatory activity
BRPI0613680-0A BRPI0613680A2 (en) 2005-07-22 2006-07-20 thiocolchicoside analogues, pharmaceutical compositions and their uses
AU2006271923A AU2006271923A1 (en) 2005-07-22 2006-07-20 Thiocolchicoside analogues with myorelaxant and anti-inflammatory activity
CNA2006800267270A CN101228175A (en) 2005-07-22 2006-07-20 Thiocolchicoside analogues with myorelaxant and anti-inflammatory activity
PCT/EP2006/007108 WO2007009772A1 (en) 2005-07-22 2006-07-20 Thiocolchicoside analogues with myorelaxant and anti-inflammatory activity
RU2008102251/04A RU2008102251A (en) 2005-07-22 2006-07-20 ANALOGUES OF THIOCOLCHICOSIDE WITH MYORELAXANT AND ANTI-INFLAMMATORY ACTIVITY
KR1020087001654A KR20080036585A (en) 2005-07-22 2006-07-20 Thiocolchicoside analogues with myorelaxant and anti-inflammatory activity
NO20080377A NO20080377L (en) 2005-07-22 2008-01-21 Thiocochicoside analogues with myorelaxative and anti-inflammatory activity
IL188900A IL188900A0 (en) 2005-07-22 2008-01-21 Thiocolchicoside analogues with myorelaxant and anti-inflammatory activity

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT001418A ITMI20051418A1 (en) 2005-07-22 2005-07-22 ANALOGUES OF THIOILCYCOSIDE WITH HYDRO-LASER ACTIVITY AND ANTI-INFLAMMATORY

Publications (1)

Publication Number Publication Date
ITMI20051418A1 true ITMI20051418A1 (en) 2007-01-23

Family

ID=37420844

Family Applications (1)

Application Number Title Priority Date Filing Date
IT001418A ITMI20051418A1 (en) 2005-07-22 2005-07-22 ANALOGUES OF THIOILCYCOSIDE WITH HYDRO-LASER ACTIVITY AND ANTI-INFLAMMATORY

Country Status (14)

Country Link
EP (1) EP1907405A1 (en)
JP (1) JP2009502755A (en)
KR (1) KR20080036585A (en)
CN (1) CN101228175A (en)
AU (1) AU2006271923A1 (en)
BR (1) BRPI0613680A2 (en)
CA (1) CA2615860A1 (en)
IL (1) IL188900A0 (en)
IT (1) ITMI20051418A1 (en)
MX (1) MX2008000968A (en)
NO (1) NO20080377L (en)
NZ (1) NZ565265A (en)
RU (1) RU2008102251A (en)
WO (1) WO2007009772A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8421747B2 (en) * 2008-09-24 2013-04-16 Microsoft Corporation Object detection and user settings
EP2435403A4 (en) * 2009-05-27 2015-04-01 Takeda Pharmaceuticals Usa Inc Thiocolchicine derivatives, method of making and methods of use thereof
EP2526086A2 (en) * 2010-01-22 2012-11-28 Mutual Pharmaceutical Company, Inc. Thiocolchicine and colchicine analogs, methods of making and methods of use thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1291550B1 (en) * 1997-04-11 1999-01-11 Indena Spa DERIVATIVES OF COLCHICINE AND THIOCOLCHICINE WITH ANTI-INFLAMMATORY AND MYORELAXING ACTIVITIES
ITMI20031144A1 (en) * 2003-06-06 2004-12-07 Indena Spa COLCHICOSIDE ANALOGUES.

Also Published As

Publication number Publication date
AU2006271923A1 (en) 2007-01-25
NO20080377L (en) 2008-02-01
WO2007009772A1 (en) 2007-01-25
IL188900A0 (en) 2008-04-13
CN101228175A (en) 2008-07-23
EP1907405A1 (en) 2008-04-09
RU2008102251A (en) 2009-07-27
JP2009502755A (en) 2009-01-29
CA2615860A1 (en) 2007-01-25
NZ565265A (en) 2010-01-29
MX2008000968A (en) 2008-03-26
KR20080036585A (en) 2008-04-28
BRPI0613680A2 (en) 2011-01-25

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