ITMI20040954A1 - Derivati del 3,6-diazabiciclo 3.1.i.eptano ad attivita' analgesica - Google Patents

Derivati del 3,6-diazabiciclo 3.1.i.eptano ad attivita' analgesica

Info

Publication number
ITMI20040954A1
ITMI20040954A1 IT000954A ITMI20040954A ITMI20040954A1 IT MI20040954 A1 ITMI20040954 A1 IT MI20040954A1 IT 000954 A IT000954 A IT 000954A IT MI20040954 A ITMI20040954 A IT MI20040954A IT MI20040954 A1 ITMI20040954 A1 IT MI20040954A1
Authority
IT
Italy
Prior art keywords
diazabiciclo
heptane
derivatives
analgesic activity
analgesic
Prior art date
Application number
IT000954A
Other languages
English (en)
Italian (it)
Inventor
Giorgio Cignarella
Giovanni Loriga
Gerard Aime Pinna
Original Assignee
Univ Degli Studi Milano
Uni Degli Studi Di Sassari
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Degli Studi Milano, Uni Degli Studi Di Sassari filed Critical Univ Degli Studi Milano
Priority to IT000954A priority Critical patent/ITMI20040954A1/it
Publication of ITMI20040954A1 publication Critical patent/ITMI20040954A1/it
Priority to EP05747942A priority patent/EP1751164A1/en
Priority to US11/596,083 priority patent/US20070225492A1/en
Priority to JP2007512054A priority patent/JP2007537182A/ja
Priority to PCT/EP2005/004994 priority patent/WO2005108402A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IT000954A 2004-05-12 2004-05-12 Derivati del 3,6-diazabiciclo 3.1.i.eptano ad attivita' analgesica ITMI20040954A1 (it)

Priority Applications (5)

Application Number Priority Date Filing Date Title
IT000954A ITMI20040954A1 (it) 2004-05-12 2004-05-12 Derivati del 3,6-diazabiciclo 3.1.i.eptano ad attivita' analgesica
EP05747942A EP1751164A1 (en) 2004-05-12 2005-05-09 3,6-diazabicyclos[3.1.1]heptane derivatives with analgesic activity
US11/596,083 US20070225492A1 (en) 2004-05-12 2005-05-09 3,6-Diazabicyclo[3.1.1]Heptane Derivatives with Analgesic Activity
JP2007512054A JP2007537182A (ja) 2004-05-12 2005-05-09 鎮痛活性を有する３，６−ジアザビシクロ［３．１．１］ヘプタン誘導体
PCT/EP2005/004994 WO2005108402A1 (en) 2004-05-12 2005-05-09 3,6-diazabicyclos[3.1.1]heptane derivatives with analgesic activity

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT000954A ITMI20040954A1 (it) 2004-05-12 2004-05-12 Derivati del 3,6-diazabiciclo 3.1.i.eptano ad attivita' analgesica

Publications (1)

Publication Number Publication Date
ITMI20040954A1 true ITMI20040954A1 (it) 2004-08-12

Family

ID=34969286

Family Applications (1)

Application Number Title Priority Date Filing Date
IT000954A ITMI20040954A1 (it) 2004-05-12 2004-05-12 Derivati del 3,6-diazabiciclo 3.1.i.eptano ad attivita' analgesica

Country Status (5)

Country Link
US (1) US20070225492A1 (https=)
EP (1) EP1751164A1 (https=)
JP (1) JP2007537182A (https=)
IT (1) ITMI20040954A1 (https=)
WO (1) WO2005108402A1 (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1395452B1 (it) * 2009-02-25 2012-09-21 Neuroscienze Pharmaness S C A Rl Microemulsioni
IT1390848B1 (it) 2008-07-31 2011-10-19 Neuroscienze Pharmaness S C A R L Composti farmaceutici
EP2149370A1 (en) 2008-07-31 2010-02-03 Neuroscienze Pharmaness S.C. A R.L. Diazabicyclic compounds and microemulsions thereof
IT1390850B1 (it) * 2008-07-31 2011-10-19 Neuroscienze Pharmaness S C A R L Microemulsioni
US8802694B2 (en) 2009-12-07 2014-08-12 Targacept, Inc. 3,6-diazabicyclo[3.1.1]heptanes as neuronal nicotinic acetycholine receptor ligands
IT1396951B1 (it) 2009-12-18 2012-12-20 Neuroscienze Pharmaness S C A R L Composti farmaceutici
WO2012125518A1 (en) 2011-03-14 2012-09-20 Targacept, Inc. Salt forms of 3 - cyclopropylcarbonyl - 3, 6 - diazabicyclo [3.1.1] heptane
WO2014011863A1 (en) * 2012-07-12 2014-01-16 Targacept, Inc. Method of treatment with 3-cyclopropylcarbonyl-3,6-diazabicyclo[3.1.1]heptane
WO2015019365A1 (en) 2013-08-07 2015-02-12 Cadila Healthcare Limited N-cyanomethylamides as inhibitors of janus kinase
US10231970B2 (en) * 2014-09-30 2019-03-19 NV Heterocycles Methods of producing heteropolycycles via bis-epoxidation
CN111892599B (zh) * 2020-08-14 2023-01-13 黄芳 一种2,5-二氮杂双环[2.2.2]辛烷-2-羧酸叔丁酯的合成方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1274018B (it) * 1994-02-23 1997-07-14 Riace Ets Derivati del 3,8-diazabiciclo(3.2.1.)ottano ad attivita' analgesica
ES2305373T3 (es) * 1999-01-29 2008-11-01 Abbott Laboratories Derivados diazabiciclicos como ligandos del receptor nicotinico de la acetilcolina.
JP2003534344A (ja) * 2000-05-25 2003-11-18 ターガセプト，インコーポレイテッド ニコチン性コリン受容体リガンドとしてのヘテロアリールジアザビシクロアルカン
NZ537182A (en) * 2002-07-26 2006-07-28 Neurosearch As Diazabicyclononane and -decane derivatives and their use as opioid receptor ligands

Also Published As

Publication number Publication date
US20070225492A1 (en) 2007-09-27
WO2005108402A1 (en) 2005-11-17
JP2007537182A (ja) 2007-12-20
EP1751164A1 (en) 2007-02-14

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