ITAN20110027A1 - MIXTURE OF FUNCTIONAL PRINCIPLES TO INTEGRATE THE IRON IN THE HUMAN DIET. - Google Patents
MIXTURE OF FUNCTIONAL PRINCIPLES TO INTEGRATE THE IRON IN THE HUMAN DIET. Download PDFInfo
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- ITAN20110027A1 ITAN20110027A1 IT000027A ITAN20110027A ITAN20110027A1 IT AN20110027 A1 ITAN20110027 A1 IT AN20110027A1 IT 000027 A IT000027 A IT 000027A IT AN20110027 A ITAN20110027 A IT AN20110027A IT AN20110027 A1 ITAN20110027 A1 IT AN20110027A1
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- Prior art keywords
- food supplement
- mixture
- iron
- active ingredients
- supplement according
- Prior art date
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- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 title claims description 39
- 239000000203 mixture Substances 0.000 title claims description 26
- 229910052742 iron Inorganic materials 0.000 title claims description 18
- 235000006486 human diet Nutrition 0.000 title description 3
- 235000015872 dietary supplement Nutrition 0.000 claims description 17
- 239000004480 active ingredient Substances 0.000 claims description 16
- 239000002775 capsule Substances 0.000 claims description 14
- 239000006188 syrup Substances 0.000 claims description 14
- 235000020357 syrup Nutrition 0.000 claims description 14
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims description 12
- OVBPIULPVIDEAO-LBPRGKRZSA-N folic acid Chemical compound C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-LBPRGKRZSA-N 0.000 claims description 8
- 235000013305 food Nutrition 0.000 claims description 7
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 claims description 6
- 108010063045 Lactoferrin Proteins 0.000 claims description 6
- 229930003761 Vitamin B9 Natural products 0.000 claims description 6
- 229930003268 Vitamin C Natural products 0.000 claims description 6
- CSSYQJWUGATIHM-IKGCZBKSSA-N l-phenylalanyl-l-lysyl-l-cysteinyl-l-arginyl-l-arginyl-l-tryptophyl-l-glutaminyl-l-tryptophyl-l-arginyl-l-methionyl-l-lysyl-l-lysyl-l-leucylglycyl-l-alanyl-l-prolyl-l-seryl-l-isoleucyl-l-threonyl-l-cysteinyl-l-valyl-l-arginyl-l-arginyl-l-alanyl-l-phenylal Chemical compound C([C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CS)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(O)=O)C1=CC=CC=C1 CSSYQJWUGATIHM-IKGCZBKSSA-N 0.000 claims description 6
- 235000021242 lactoferrin Nutrition 0.000 claims description 6
- 229940078795 lactoferrin Drugs 0.000 claims description 6
- 235000019159 vitamin B9 Nutrition 0.000 claims description 6
- 239000011727 vitamin B9 Substances 0.000 claims description 6
- 235000019154 vitamin C Nutrition 0.000 claims description 6
- 239000011718 vitamin C Substances 0.000 claims description 6
- 239000013589 supplement Substances 0.000 claims description 5
- 241000196324 Embryophyta Species 0.000 claims description 4
- 238000009472 formulation Methods 0.000 claims description 4
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 claims description 4
- 239000000843 powder Substances 0.000 claims description 4
- 235000013311 vegetables Nutrition 0.000 claims description 4
- CHHHXKFHOYLYRE-UHFFFAOYSA-M 2,4-Hexadienoic acid, potassium salt (1:1), (2E,4E)- Chemical compound [K+].CC=CC=CC([O-])=O CHHHXKFHOYLYRE-UHFFFAOYSA-M 0.000 claims description 3
- 244000025254 Cannabis sativa Species 0.000 claims description 3
- 244000000626 Daucus carota Species 0.000 claims description 3
- 235000002767 Daucus carota Nutrition 0.000 claims description 3
- 239000005715 Fructose Substances 0.000 claims description 3
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 claims description 3
- 229930091371 Fructose Natural products 0.000 claims description 3
- 244000211187 Lepidium sativum Species 0.000 claims description 3
- 235000007849 Lepidium sativum Nutrition 0.000 claims description 3
- 240000008530 Rosa canina Species 0.000 claims description 3
- 235000000539 Rosa canina Nutrition 0.000 claims description 3
- 235000010337 Rosa dumalis Nutrition 0.000 claims description 3
- 244000300264 Spinacia oleracea Species 0.000 claims description 3
- 235000009337 Spinacia oleracea Nutrition 0.000 claims description 3
- 244000274883 Urtica dioica Species 0.000 claims description 3
- 235000009108 Urtica dioica Nutrition 0.000 claims description 3
- CADNYOZXMIKYPR-UHFFFAOYSA-B ferric pyrophosphate Chemical compound [Fe+3].[Fe+3].[Fe+3].[Fe+3].[O-]P([O-])(=O)OP([O-])([O-])=O.[O-]P([O-])(=O)OP([O-])([O-])=O.[O-]P([O-])(=O)OP([O-])([O-])=O CADNYOZXMIKYPR-UHFFFAOYSA-B 0.000 claims description 3
- 235000015205 orange juice Nutrition 0.000 claims description 3
- 229940069338 potassium sorbate Drugs 0.000 claims description 3
- 235000010241 potassium sorbate Nutrition 0.000 claims description 3
- 239000004302 potassium sorbate Substances 0.000 claims description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 3
- 229920000168 Microcrystalline cellulose Polymers 0.000 claims description 2
- 235000019359 magnesium stearate Nutrition 0.000 claims description 2
- 235000019813 microcrystalline cellulose Nutrition 0.000 claims description 2
- 239000008108 microcrystalline cellulose Substances 0.000 claims description 2
- 229940016286 microcrystalline cellulose Drugs 0.000 claims description 2
- 102000010445 Lactoferrin Human genes 0.000 claims 1
- 239000000796 flavoring agent Substances 0.000 claims 1
- 235000019634 flavors Nutrition 0.000 claims 1
- 102100032241 Lactotransferrin Human genes 0.000 description 5
- 239000004615 ingredient Substances 0.000 description 4
- 239000000047 product Substances 0.000 description 4
- 238000010521 absorption reaction Methods 0.000 description 3
- 239000007864 aqueous solution Substances 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 159000000014 iron salts Chemical class 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 239000007787 solid Substances 0.000 description 2
- 102000014914 Carrier Proteins Human genes 0.000 description 1
- 108010078791 Carrier Proteins Proteins 0.000 description 1
- 102000001554 Hemoglobins Human genes 0.000 description 1
- 108010054147 Hemoglobins Proteins 0.000 description 1
- OVBPIULPVIDEAO-UHFFFAOYSA-N N-Pteroyl-L-glutaminsaeure Natural products C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)NC(CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-UHFFFAOYSA-N 0.000 description 1
- 239000006286 aqueous extract Substances 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 239000012467 final product Substances 0.000 description 1
- 235000019152 folic acid Nutrition 0.000 description 1
- 239000011724 folic acid Substances 0.000 description 1
- 229960000304 folic acid Drugs 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 238000005469 granulation Methods 0.000 description 1
- 230000003179 granulation Effects 0.000 description 1
- 230000010354 integration Effects 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 230000035935 pregnancy Effects 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
- A61K31/295—Iron group metal compounds
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/15—Vitamins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/16—Inorganic salts, minerals or trace elements
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/19—Dairy proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/21—Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/738—Rosa (rose)
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biotechnology (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Botany (AREA)
- Alternative & Traditional Medicine (AREA)
- Food Science & Technology (AREA)
- Nutrition Science (AREA)
- Polymers & Plastics (AREA)
- Inorganic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Description
DESCRIZIONE DESCRIPTION
a corredo di una domanda di brevetto per invenzione industriale avente per titolo: accompanying a patent application for an industrial invention entitled:
"MISCELA DI PRINCIPI FUNZIONALI ATTI AD INTEGRARE IL FERRO NELLA DIETA UMANA” "BLEND OF FUNCTIONAL PRINCIPLES ACTS TO INTEGRATE IRON INTO THE HUMAN DIET"
TESTO DELLA DESCRIZIONE TEXT OF THE DESCRIPTION
La presente domanda di brevetto per invenzione industriale ha per oggetto un integratore alimentare, allo scopo di integrare il ferro nella dieta umana. The present patent application for industrial invention relates to a food supplement, for the purpose of integrating iron in the human diet.
Come è noto, Γ organismo umano necessita una certa quantità di ferro. As is known, the human body needs a certain amount of iron.
Sono noti in commercio vari tipi di integratori di ferro, generalmente sotto forma di capsule, compresse e sciroppi. Tuttavia gli integratori attualmente utilizzati presentano inconvenienti dovuti al fatto che non riescono ad integrare un’adeguata quantità di ferro, i tempi di integrazione del ferro sono molto lunghi, l’integratore è poco digeribile e presenta degli effetti collaterali nocivi per il soggetto. Various types of iron supplements are known on the market, generally in the form of capsules, tablets and syrups. However, the supplements currently used have drawbacks due to the fact that they are unable to integrate an adequate amount of iron, the iron integration times are very long, the supplement is not very digestible and has harmful side effects for the subject.
Scopo della presente invenzione è di eliminare gli inconvenienti della tecnica nota, fornendo un integratore alimentare che sia efficace, efficiente e in grado di integrare un’elevata quantità di ferro. The purpose of the present invention is to eliminate the drawbacks of the known art, providing a food supplement that is effective, efficient and capable of integrating a high amount of iron.
Altro scopo della presente invenzione è di fornire un tale integratore alimentare che sia digeribile per il paziente e riduca al minimo gli effetti collaterali. Another object of the present invention is to provide such a food supplement which is digestible for the patient and minimizes side effects.
Questi scopi sono raggiunti in accordo all 'invenzione, con le caratteristiche elencate nell’ annessa rivendicazione indipendente 1. These purposes are achieved in accordance with the invention, with the characteristics listed in the attached independent claim 1.
Realizzazioni vantaggiose appaiono dalle rivendicazioni dipendenti. Advantageous embodiments appear from the dependent claims.
L’integratore alimentare dell’elemento ferro, secondo l’invenzione, comprende alimenti vegetali e una miscela di principi attivi comprendente i seguenti componenti: Ferro, Vitamina C, Vitamina B9e Lattoferrina. The food supplement of the iron element, according to the invention, includes plant foods and a mixture of active ingredients including the following components: Iron, Vitamin C, Vitamin B9 and Lactoferrin.
Ulteriori caratteristiche dell’invenzione appariranno più chiare dalla descrizione dettagliata che segue, riferita a una sua forma di realizzazione puramente esemplificativa e quindi non limitativa. Further features of the invention will become clearer from the detailed description that follows, referring to a purely exemplary and therefore non-limiting embodiment thereof.
L’invenzione ha per oggetto la creazione di una miscela funzionale di principi attivi la quale, una volta inserita all’intemo di un integratore alimentare, favorisca efficacemente e velocemente l’assorbimento dell’elemento ferro. The invention has as its object the creation of a functional mixture of active ingredients which, once inserted into a food supplement, effectively and quickly promote the absorption of the iron element.
La miscela di principi attivi secondo l’invenzione comprende Ferro, Vitamina C, Vitamina B9e Lattoferrina. Vantaggiosamente si usa ferro pirofosfato microincapsulato. The mixture of active ingredients according to the invention includes Iron, Vitamin C, Vitamin B9 and Lactoferrin. Advantageously, microencapsulated iron pyrophosphate is used.
Per la produzione di tale miscela di principi attivi si usano componenti in polvere di Ferro, Vitamina C, Vitamina B9e Lattoferrina che vengono miscelate tra loro. La miscela ottenuta viene successivamente granulata ed essiccata. Il granulato così ottenuto è pronto per essere inserito nel prodotto finito che è un integratore alimentare. Tale integratore alimentare vantaggiosamente può essere venduto in forma solida (capsule) o in forma liquida (sciroppo). For the production of this mixture of active ingredients, powdered components of Iron, Vitamin C, Vitamin B9 and Lactoferrin are used, which are mixed together. The obtained mixture is subsequently granulated and dried. The granulate thus obtained is ready to be inserted into the finished product which is a food supplement. This food supplement can advantageously be sold in solid form (capsules) or in liquid form (syrup).
La formulazione preferita della miscela di principi attivi, secondo Γ invenzione, è riportata nella tabella 1 che segue: The preferred formulation of the mixture of active ingredients, according to the invention, is reported in the following table 1:
Tabella 1 Table 1
Bisogna considerare un range di 10% rispetto alle percentuali peso riportate in tabella 1. It is necessary to consider a range of 10% with respect to the weight percentages shown in table 1.
Il Ferro viene inserito come ingrediente centrale della formulazione in quanto lo scopo del prodotto è quello di integrare tale elemento. La forma microincapsulata del ferro pirofosfato permette un migliore assorbimento deH’elemento ed un minore impatto sul sistema gastrico, evitando fastidi e bruciori dovuti all’assunzione di altri sali di Ferro. Iron is included as a central ingredient of the formulation as the purpose of the product is to integrate this element. The microencapsulated form of iron pyrophosphate allows better absorption of the element and a lower impact on the gastric system, avoiding discomfort and burning due to the intake of other iron salts.
Da numerosi studi emerge che il ferro inorganico (come la maggior parte dei sali di ferro attualmente in commercio) è praticamente indisponibile senza l’aiuto della vitamina C, da qui il suo inserimento nel composto. Numerous studies show that inorganic iron (like most iron salts currently on the market) is practically unavailable without the help of vitamin C, hence its inclusion in the compound.
Da ulteriori studi emerge che la Lattoferrina, proteina trasportatrice del ferro, contribuisce significativamente all’ assorbimento di tale elemento, specialmente nelle donne in gravidanza. Further studies show that Lactoferrin, an iron carrier protein, significantly contributes to the absorption of this element, especially in pregnant women.
Infine la vitamina B9, presente di per se come integrazione di acido folico indispensabile durante la gestazione, favorisce la formazione di nuova emoglobina trasportatrice di ferro. Finally, vitamin B9, present in itself as an essential supplement of folic acid during gestation, favors the formation of new iron-carrying hemoglobin.
La granulazione di questi quattro principi attivi permette la creazione di una miscela, la quale racchiude al suo interno tali sostanze e permette che esse agiscano sinergicamente ed esplichino un effetto più marcato all’intemo dell’organismo. The granulation of these four active ingredients allows the creation of a mixture, which contains these substances and allows them to act synergistically and exert a more pronounced effect within the body.
La miscela viene inserita in due prodotti, uno in formato solido granulare (capsula) e l’altro in formato liquido (sciroppo). The mixture is inserted into two products, one in solid granular format (capsule) and the other in liquid format (syrup).
Entrambe i prodotti, vantaggiosamente contegono i seguenti alimenti vegetali: rosa canina, ortica, carota, spinacio, gramigna, crescione. I suddetti alimenti sono naturalmente ricchi di Ferro e vengono pertanto inseriti allo scopo di implementare qualitativamente il prodotto finale. Both products advantageously contain the following plant foods: dog rose, nettle, carrot, spinach, grass, cress. The aforementioned foods are naturally rich in Iron and are therefore included in order to qualitatively implement the final product.
La capsula, oltre agli alimenti vegetali summenzionati, prevede inoltre cellulosa microcristallina e magnesio stearato vegetale, quali eccipienti tecnologici del processo produttivo della capsula stessa. The capsule, in addition to the aforementioned vegetable foods, also includes microcrystalline cellulose and vegetable magnesium stearate, as technological excipients of the capsule production process.
Lo sciroppo, oltre agli alimenti vegetali summenzionati, prevede inoltre succo di arancio, aroma, fruttosio, potassio sorbato e acqua. I suddetti componenti svolgono azione aromatizzante, edulcorante e conservante dello sciroppo stesso. The syrup, in addition to the aforementioned plant foods, also provides orange juice, flavoring, fructose, potassium sorbate and water. The aforementioned components carry out an aromatizing, sweetening and preserving action of the syrup itself.
Per la realizzazione della capsula, vengono utilizzati tutti gli ingredienti in forma granulare di polvere e vengono miscelati tra loro. La miscela di polvere ottenuta viene incapsulata. To make the capsule, all the ingredients are used in granular form of powder and are mixed together. The resulting powder mixture is encapsulated.
La capsula contiene una percentuale in peso della miscela di principi attivi pari a circa 44 - 46 %, preferibilmente 45,28%, rispetto al peso totale di tutti gli ingredienti della capsula. The capsule contains a weight percentage of the mixture of active ingredients equal to about 44 - 46%, preferably 45.28%, with respect to the total weight of all the ingredients of the capsule.
La preparazione dello sciroppo prevede una premiscelazione di acqua e potassio sorbato in modo da ottenere una soluzione acquosa. Nella soluzione acquosa ottenuta vengono disciolti in sequenza: la miscela in polvere di principi attivi e il fruttosio. Nella soluzione acquosa ottenuta si aggiunge un estratto acquoso di rosa canina, ortica, carota, spinacio, gramigna e crescione. Il tutto viene aromatizzato con succo di arancio e aroma. The preparation of the syrup involves a premixing of water and potassium sorbate in order to obtain an aqueous solution. In the aqueous solution obtained, the following are dissolved in sequence: the powder mixture of active ingredients and fructose. An aqueous extract of dog rose, nettle, carrot, spinach, grass and cress is added to the aqueous solution obtained. Everything is flavored with orange juice and aroma.
Lo sciroppo contiene una percentuale in peso della miscela di principi attivi pari a circa 1,50 - 1,90 %, preferibilmente 1,69%, rispetto al peso totale di tutti gli ingredienti dello sciroppo. The syrup contains a percentage by weight of the mixture of active ingredients equal to about 1.50 - 1.90%, preferably 1.69%, with respect to the total weight of all the ingredients of the syrup.
La percentuale peso di miscela di principi attivi inserita nelle formulazioni della capsula e dello sciroppo non è la stessa. Questo perché la forma galenica (capsula o sciroppo) comporta due modalità di assunzione differenti. Il soggetto deve assumere due capsule al giorno oppure 20 mi al giorno di sciroppo. The percentage weight of the mixture of active ingredients included in the capsule and syrup formulations is not the same. This is because the galenic form (capsule or syrup) involves two different modes of intake. The subject should take two capsules per day or 20 ml per day of syrup.
Tale percentuale peso di miscela di principi attivi è calibrata esattamente in modo che Γ assunzione giornaliera di capsule o sciroppo apporti sempre e comunque: This percentage weight of the mixture of active ingredients is calibrated exactly so that Γ daily intake of capsules or syrup always and in any case:
Ferro = 21 mg Iron = 21 mg
Vitamina C = 80 mg Vitamin C = 80 mg
Vitamina B9= 400 mcg Vitamin B9 = 400 mcg
Lattoferrina = 30 mg Lactoferrin = 30 mg
Claims (9)
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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EP3892118A1 (en) * | 2020-04-06 | 2021-10-13 | artgerecht GmbH | Iron-containing formulation, nutritional composition containing this formulation, and use thereof |
Citations (4)
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EP0409252A2 (en) * | 1989-07-21 | 1991-01-23 | Snow Brand Milk Products Co., Ltd. | Method of preparing iron-fortified beverage |
DE20012510U1 (en) * | 2000-07-17 | 2000-11-30 | Klingmueller Martin | Multivitamin and mineral preparation |
WO2005051088A2 (en) * | 2003-11-12 | 2005-06-09 | Abbott Laboratories | Iron-containing human milk fortifier with improved antimicrobial properties |
EP2266551A1 (en) * | 2001-11-20 | 2010-12-29 | Procter & Gamble, Inc. | Compositions and kits comprising a defined boron compound and methods of their preparation |
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Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
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EP0409252A2 (en) * | 1989-07-21 | 1991-01-23 | Snow Brand Milk Products Co., Ltd. | Method of preparing iron-fortified beverage |
DE20012510U1 (en) * | 2000-07-17 | 2000-11-30 | Klingmueller Martin | Multivitamin and mineral preparation |
EP2266551A1 (en) * | 2001-11-20 | 2010-12-29 | Procter & Gamble, Inc. | Compositions and kits comprising a defined boron compound and methods of their preparation |
WO2005051088A2 (en) * | 2003-11-12 | 2005-06-09 | Abbott Laboratories | Iron-containing human milk fortifier with improved antimicrobial properties |
Non-Patent Citations (8)
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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EP3892118A1 (en) * | 2020-04-06 | 2021-10-13 | artgerecht GmbH | Iron-containing formulation, nutritional composition containing this formulation, and use thereof |
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