IT9020822A0 - - Google Patents

Info

Publication number
IT9020822A0
IT9020822A0 IT20822A IT2082290A IT9020822A0 IT 9020822 A0 IT9020822 A0 IT 9020822A0 IT 20822 A IT20822 A IT 20822A IT 2082290 A IT2082290 A IT 2082290A IT 9020822 A0 IT9020822 A0 IT 9020822A0
Authority
IT
Italy
Application number
IT20822A
Other versions
IT1249034B (it
IT9020822A1 (it
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of IT9020822A0 publication Critical patent/IT9020822A0/it
Priority to IT02082290A priority Critical patent/IT1249034B/it
Priority to EP19910110544 priority patent/EP0463614A3/en
Priority to JP3158334A priority patent/JPH04230327A/ja
Priority to PT98160A priority patent/PT98160A/pt
Priority to CA002045982A priority patent/CA2045982A1/en
Priority to US07/723,280 priority patent/US5183807A/en
Priority to HU912186A priority patent/HUT58206A/hu
Priority to KR1019910011010A priority patent/KR920000326A/ko
Priority to AU79484/91A priority patent/AU7948491A/en
Publication of IT9020822A1 publication Critical patent/IT9020822A1/it
Application granted granted Critical
Publication of IT1249034B publication Critical patent/IT1249034B/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/30—Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Molecular Biology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IT02082290A 1990-06-29 1990-06-29 Impiego del monosialoganglioside gm1 e del suo derivato estere interno per impedire l'instaurarsi della tolleranza nell'uomo all'effetto analgesico della morfina e analoghi IT1249034B (it)

Priority Applications (9)

Application Number Priority Date Filing Date Title
IT02082290A IT1249034B (it) 1990-06-29 1990-06-29 Impiego del monosialoganglioside gm1 e del suo derivato estere interno per impedire l'instaurarsi della tolleranza nell'uomo all'effetto analgesico della morfina e analoghi
EP19910110544 EP0463614A3 (en) 1990-06-29 1991-06-26 The use of the gm1 monosialoganglioside and of its internal ester derivative to prevent the insurgence in man of the tolerance to the analgesic effect of morphine and analogues
CA002045982A CA2045982A1 (en) 1990-06-29 1991-06-28 Use of the gm monosialoganglioside and of its internal ester derivative to prevent the insurgence in man of the
PT98160A PT98160A (pt) 1990-06-29 1991-06-28 Processo para a preparacao de composicoes farmaceuticas contendo monossialogangliosido gm1
JP3158334A JPH04230327A (ja) 1990-06-29 1991-06-28 モルヒネおよびその類似体の鎮痛作用に対する耐性の発現を防止する方法
US07/723,280 US5183807A (en) 1990-06-29 1991-06-28 Use of monosialoganglioside gm, to prevent the development of tolerance to the analgesic effect of morphine and related drugs
HU912186A HUT58206A (en) 1990-06-29 1991-06-28 Process for utilizing gm1-monosilano-gangliozide and inner esters for inhibiting habit to morphine and analogues in human patients
KR1019910011010A KR920000326A (ko) 1990-06-29 1991-06-29 사람에 있어서 몰핀 및 동족체의 진통 효과에 대한 내성 발생을 방지하기 위한 gm₁모노시알로강글리오사이드 및 이의 내부 에스테르 유도체의 용도
AU79484/91A AU7948491A (en) 1990-06-29 1991-07-01 The use of the gm1 monosialoganglioside and of its internal ester derivative to prevent the insurgence in man of the tolerance to the analgesic effect of morphine and analogues

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT02082290A IT1249034B (it) 1990-06-29 1990-06-29 Impiego del monosialoganglioside gm1 e del suo derivato estere interno per impedire l'instaurarsi della tolleranza nell'uomo all'effetto analgesico della morfina e analoghi

Publications (3)

Publication Number Publication Date
IT9020822A0 true IT9020822A0 (it) 1990-06-29
IT9020822A1 IT9020822A1 (it) 1991-12-29
IT1249034B IT1249034B (it) 1995-02-11

Family

ID=11172568

Family Applications (1)

Application Number Title Priority Date Filing Date
IT02082290A IT1249034B (it) 1990-06-29 1990-06-29 Impiego del monosialoganglioside gm1 e del suo derivato estere interno per impedire l'instaurarsi della tolleranza nell'uomo all'effetto analgesico della morfina e analoghi

Country Status (9)

Country Link
US (1) US5183807A (it)
EP (1) EP0463614A3 (it)
JP (1) JPH04230327A (it)
KR (1) KR920000326A (it)
AU (1) AU7948491A (it)
CA (1) CA2045982A1 (it)
HU (1) HUT58206A (it)
IT (1) IT1249034B (it)
PT (1) PT98160A (it)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1251991B (it) * 1991-11-08 1995-05-27 Fidia Spa Impiego di gangliosidi per la preparazione di composizioni farmaceutiche attive nella prevenzione di disfunzioni associate all'abuso di cocaina e psicostimolanti ad essa collegati
IT1254280B (it) * 1992-03-13 1995-09-14 Fidia Spa Composizioni farmaceutiche comprendenti monosialoganglioside gm1 o un suo derivato atte al trattamento della malattia di parkinson
USRE39300E1 (en) 1993-01-28 2006-09-19 Virginia Commonwealth University Medical College Of Virginia Inhibiting the development of tolerance to and/or dependence on an addictive substance
US5321012A (en) * 1993-01-28 1994-06-14 Virginia Commonwealth University Medical College Inhibiting the development of tolerance to and/or dependence on a narcotic addictive substance
US5834479A (en) * 1993-03-05 1998-11-10 Mayer; David J. Method and composition for alleviating pain
US6919373B1 (en) 1996-11-12 2005-07-19 Alza Corporation Methods and devices for providing prolonged drug therapy
US6962930B1 (en) 1997-06-06 2005-11-08 Lohocla Research Corporation Compounds, compositions and method suitable for amelioration of withdrawal syndromes and withdrawal-induced brain damage
AU2002326805B2 (en) 2001-08-29 2009-01-22 Seneb Biosciences, Inc. Novel synthetic ganglioside derivatives and compositions thereof
AU2003219680A1 (en) * 2002-01-23 2003-09-02 The Regents Of The University Of California Methods and compositions for reducing the development of drug tolerance and/or physical dependence
NZ542148A (en) 2003-03-06 2008-05-30 Neose Technologies Inc Methods and compositions for the enzymatic synthesis of gangliosides
US20080241121A1 (en) * 2007-04-02 2008-10-02 Daniela Salvemini Inhibitors of the ceramide metabolic pathway as adjuncts to opiates for pain
US20100086543A1 (en) * 2007-04-02 2010-04-08 Saint Louis University Compositions and methods for treating conditions associated with ceramide biosynthesis
US20120035120A1 (en) 2009-03-25 2012-02-09 Seneb Biosciences, Inc. Glycolipids as treatment for disease

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4476119A (en) * 1981-08-04 1984-10-09 Fidia S.P.A. Method for preparing ganglioside derivatives and use thereof in pharmaceutical compositions
IT1212896B (it) * 1983-11-08 1989-11-30 Della Valle Francesco Metodo di somministrazione per via inalatoria di gangliosidi e derivati, e composizioni farmaceutiche relative
IT1177863B (it) * 1984-07-03 1987-08-26 Fidia Farmaceutici Una miscela gangliosidica come agente terapeutico capare di eliminare il dolore nele neuropatie periferiche
IT1182209B (it) * 1985-02-18 1987-09-30 Fidia Farmaceutici Uso terapeutico del monosialoganglioside gm1 e dei suoi derivati in gravi patologie di infarti cerebrali
IT1212041B (it) * 1987-11-02 1989-11-08 Fidia Farmaceutici Gangliosidi esteri interni come agenti terapeutici capaci di eliminare il dolore nelle neuropatie periferiche
US5066496A (en) * 1988-08-03 1991-11-19 Angio-Medical Corporation Composition and method for treatment of gastric and duodenal ulcers and mucosal erosions

Also Published As

Publication number Publication date
KR920000326A (ko) 1992-01-29
IT1249034B (it) 1995-02-11
HUT58206A (en) 1992-02-28
HU912186D0 (en) 1991-12-30
EP0463614A3 (en) 1992-07-01
JPH04230327A (ja) 1992-08-19
IT9020822A1 (it) 1991-12-29
PT98160A (pt) 1992-04-30
AU7948491A (en) 1992-01-16
US5183807A (en) 1993-02-02
EP0463614A2 (en) 1992-01-02
CA2045982A1 (en) 1991-12-30

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Legal Events

Date Code Title Description
0001 Granted