IT8822798A0 - Esteri dell'acido 3,6-diidro-1,5(2h)-pirimidincarbossilico - Google Patents

Esteri dell'acido 3,6-diidro-1,5(2h)-pirimidincarbossilico

Info

Publication number
IT8822798A0
IT8822798A0 IT8822798A IT2279888A IT8822798A0 IT 8822798 A0 IT8822798 A0 IT 8822798A0 IT 8822798 A IT8822798 A IT 8822798A IT 2279888 A IT2279888 A IT 2279888A IT 8822798 A0 IT8822798 A0 IT 8822798A0
Authority
IT
Italy
Prior art keywords
dihydro
esters
carboxylic acid
pyrimidine carboxylic
pyrimidine
Prior art date
Application number
IT8822798A
Other languages
English (en)
Other versions
IT1227646B (it
Inventor
Karnail Atwal
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of IT8822798A0 publication Critical patent/IT8822798A0/it
Application granted granted Critical
Publication of IT1227646B publication Critical patent/IT1227646B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/20—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D239/22—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IT8822798A 1987-11-30 1988-11-30 Esteri dell'acido 3,6-diidro-1,5(2h)-pirimidincarbossilico IT1227646B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/126,528 US4847379A (en) 1987-11-30 1987-11-30 3,6-dihydro-1,5(2H)-pyrimidinecarboxylic acid esters

Publications (2)

Publication Number Publication Date
IT8822798A0 true IT8822798A0 (it) 1988-11-30
IT1227646B IT1227646B (it) 1991-04-23

Family

ID=22425304

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8822798A IT1227646B (it) 1987-11-30 1988-11-30 Esteri dell'acido 3,6-diidro-1,5(2h)-pirimidincarbossilico

Country Status (7)

Country Link
US (1) US4847379A (it)
JP (1) JPH01186872A (it)
CA (1) CA1317597C (it)
DE (1) DE3840380A1 (it)
FR (1) FR2623806B1 (it)
GB (1) GB2213146B (it)
IT (1) IT1227646B (it)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2277965A1 (en) * 1997-02-04 1998-08-06 Marc A. Bruce Dihydropyrimidone derivatives as npy antagonists
US6057350A (en) * 1997-06-18 2000-05-02 Merck & Co., Inc. Alpha 1a adrenergic receptor antagonists
US6214832B1 (en) 1997-06-18 2001-04-10 Merck & Co., Inc. Bis-piperidinyl-pyrimidin-2-ones as alpha 1a adrenergic receptor antagonists
US6080760A (en) * 1997-06-18 2000-06-27 Merck & Co., Inc. Alpha 1A adrenergic receptor antagonists
US6143750A (en) * 1997-06-18 2000-11-07 Merck & Co., Inc. Alpha 1a adrenergic receptor antagonists
US6037354A (en) * 1997-06-18 2000-03-14 Merck & Co., Inc. Alpha 1a adrenergic receptor antagonists
US6376503B1 (en) 1997-06-18 2002-04-23 Merck & Co., Inc Alpha 1a adrenergic receptor antagonists
WO1999025345A1 (en) * 1997-11-14 1999-05-27 Merck & Co., Inc. Alpha-1a adrenergic receptor antagonists
AU5234899A (en) 1998-07-30 2000-02-21 Merck & Co., Inc. Alpha 1a adrenergic receptor antagonists
EP1554572B1 (en) 2001-07-25 2009-10-14 Raptor Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
WO2005007124A2 (en) 2003-07-23 2005-01-27 Bristol-Myers Squibb Company Substituted dihydropyrimidine inhibitors of calcium channel function
US7166603B2 (en) 2003-07-23 2007-01-23 Bristol-Myers Squibb Co. Dihydropyrimidone inhibitors of calcium channel function
JP4091043B2 (ja) 2004-12-22 2008-05-28 富士通メディアデバイス株式会社 分波器
EP3827747A1 (en) 2005-04-28 2021-06-02 Otsuka Pharmaceutical Co., Ltd. Pharma-informatics system
EP2063905B1 (en) 2006-09-18 2014-07-30 Raptor Pharmaceutical Inc Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates
NZ616673A (en) 2009-02-20 2014-08-29 To Bbb Holding B V Glutathione-based drug delivery system
ES2942923T3 (es) 2009-05-06 2023-06-07 Laboratory Skin Care Inc Composiciones de administración dérmica que comprenden complejos de agente activo-partículas de fosfato de calcio y métodos de uso de las mismas
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4728652A (en) * 1985-05-20 1988-03-01 E. R. Squibb & Sons, Inc. 2-substituted thio or oxy-4-aryl or heterocyclo-5-carboxy-1,4-dihydropyrimidines, composition containing them, and method of using them to reduce blood pressure
HUT42077A (en) * 1985-06-03 1987-06-29 Squibb & Sons Inc Process for producing diesters of 2-tioxo- or 2-oxo-pyrimidine-1,5-dicarboxylic acid and 1-acyl-pyrimidine-5-carboxylic acids and esters
US4675321A (en) * 1986-02-07 1987-06-23 Merck & Co., Inc. Substituted pyrimidines useful as calcium channel blockers
IL81800A0 (en) * 1986-03-14 1987-10-20 Squibb & Sons Inc 1,2,3,4-tetrahydro-6-substituted-4-aryl(or heterocyclo)-3-((substituted amino)carbonyl)-2-thioxo(or oxo)-5-pyrimidine-carboxylic acids and esters and pharmaceutical compositions containing the same

Also Published As

Publication number Publication date
GB2213146B (en) 1991-04-24
CA1317597C (en) 1993-05-11
FR2623806B1 (fr) 1991-03-22
DE3840380A1 (de) 1989-06-08
GB8827928D0 (en) 1989-01-05
US4847379A (en) 1989-07-11
IT1227646B (it) 1991-04-23
FR2623806A1 (fr) 1989-06-02
JPH01186872A (ja) 1989-07-26
GB2213146A (en) 1989-08-09

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TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19971129