IT8419372A0 - Composto ad attivita' calcio antagonista periferica, anticonvulsivante ed eumetabolica cerebrale,metodo per la sua preparazione e composizioni farmaceutiche. - Google Patents
Composto ad attivita' calcio antagonista periferica, anticonvulsivante ed eumetabolica cerebrale,metodo per la sua preparazione e composizioni farmaceutiche.Info
- Publication number
- IT8419372A0 IT8419372A0 IT8419372A IT1937284A IT8419372A0 IT 8419372 A0 IT8419372 A0 IT 8419372A0 IT 8419372 A IT8419372 A IT 8419372A IT 1937284 A IT1937284 A IT 1937284A IT 8419372 A0 IT8419372 A0 IT 8419372A0
- Authority
- IT
- Italy
- Prior art keywords
- eumetabolic
- anticonvulsant
- cerebral
- activity
- compound
- Prior art date
Links
- 229940127291 Calcium channel antagonist Drugs 0.000 title 1
- 230000001773 anti-convulsant effect Effects 0.000 title 1
- 239000001961 anticonvulsive agent Substances 0.000 title 1
- 229960003965 antiepileptics Drugs 0.000 title 1
- 239000000480 calcium channel blocker Substances 0.000 title 1
- 230000002490 cerebral effect Effects 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 230000000694 effects Effects 0.000 title 1
- 230000002093 peripheral effect Effects 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicinal Preparation (AREA)
Priority Applications (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT8419372A IT1213131B (it) | 1984-02-02 | 1984-02-02 | Composto ad attivita' calcio antagonista periferica, anticonvulsivante ed eumetabolica cerebrale,metodo per la sua preparazione e composizioni farmaceutiche. |
| DE198585100737T DE152799T1 (de) | 1984-02-02 | 1985-01-25 | Verbindungen mit peripherischen kalzium-antagonisten antikonvulsiver und eumetabolischer wirkung, verfahren zur herstellung und diese enthaltende pharmazeutische zusammensetzungen. |
| AT85100737T ATE30422T1 (de) | 1984-02-02 | 1985-01-25 | Verbindungen mit peripherischen kalziumantagonisten antikonvulsiver und eumetabolischer wirkung, verfahren zur herstellung und diese enthaltende pharmazeutische zusammensetzungen. |
| EP85100737A EP0152799B1 (en) | 1984-02-02 | 1985-01-25 | Compounds having peripheral calcium antagonist, anticonvulsive and eumetabolic activity, processes for the preparation thereof and pharmaceutical compositions containing them |
| DE8585100737T DE3560830D1 (en) | 1984-02-02 | 1985-01-25 | Compounds having peripheral calcium antagonist, anticonvulsive and eumetabolic activity, processes for the preparation thereof and pharmaceutical compositions containing them |
| ES540042A ES540042A0 (es) | 1984-02-02 | 1985-02-01 | Procedimiento para la preparacion de 1-(2,4'-difluorobenci- dril-4-(3,4-dimetoxicinamil)-piperacina |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT8419372A IT1213131B (it) | 1984-02-02 | 1984-02-02 | Composto ad attivita' calcio antagonista periferica, anticonvulsivante ed eumetabolica cerebrale,metodo per la sua preparazione e composizioni farmaceutiche. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT8419372A0 true IT8419372A0 (it) | 1984-02-02 |
| IT1213131B IT1213131B (it) | 1989-12-14 |
Family
ID=11157131
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT8419372A IT1213131B (it) | 1984-02-02 | 1984-02-02 | Composto ad attivita' calcio antagonista periferica, anticonvulsivante ed eumetabolica cerebrale,metodo per la sua preparazione e composizioni farmaceutiche. |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0152799B1 (it) |
| AT (1) | ATE30422T1 (it) |
| DE (2) | DE152799T1 (it) |
| ES (1) | ES540042A0 (it) |
| IT (1) | IT1213131B (it) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61161272A (ja) * | 1985-01-11 | 1986-07-21 | Kanebo Ltd | 新規なピペラジン誘導体および該化合物を有効成分とする医薬組成物 |
| JPS62277370A (ja) * | 1986-02-04 | 1987-12-02 | Terumo Corp | ジエン誘導体およびこれを含有する血管拡張剤 |
| US5428037A (en) * | 1993-04-09 | 1995-06-27 | Syntex Pharmaceuticals, Ltd. | Heterocyclic derivatives in the treatment of Ischaemia and related diseases |
| WO1995015958A1 (en) * | 1993-12-08 | 1995-06-15 | Alcon Laboratories, Inc. | Compounds having both potent calcium antagonist and antioxidant activity and use thereof as cytoprotective agents |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE33283B1 (en) * | 1968-07-02 | 1974-05-15 | Pharmaceutica J Nv | N-arallyl-n'-aralkyl piperazines and pharmaceutical compositions thereof |
| BE790971A (fr) * | 1971-11-09 | 1973-05-07 | Janssen Pharmaceutica Nv | Metode ter voorkoming van patologische reakties die de funktie van het komplement vereisen |
-
1984
- 1984-02-02 IT IT8419372A patent/IT1213131B/it active
-
1985
- 1985-01-25 DE DE198585100737T patent/DE152799T1/de active Pending
- 1985-01-25 EP EP85100737A patent/EP0152799B1/en not_active Expired
- 1985-01-25 AT AT85100737T patent/ATE30422T1/de not_active IP Right Cessation
- 1985-01-25 DE DE8585100737T patent/DE3560830D1/de not_active Expired
- 1985-02-01 ES ES540042A patent/ES540042A0/es active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| DE152799T1 (de) | 1986-01-02 |
| EP0152799B1 (en) | 1987-10-28 |
| EP0152799A1 (en) | 1985-08-28 |
| DE3560830D1 (en) | 1987-12-03 |
| ES8601176A1 (es) | 1985-11-01 |
| ATE30422T1 (de) | 1987-11-15 |
| ES540042A0 (es) | 1985-11-01 |
| IT1213131B (it) | 1989-12-14 |
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