IT8320334A0 - PROCESS FOR THE PREPARATION OF CLOBETASOL 17-ESTERS AND COMPOUNDS OBTAINED. - Google Patents
PROCESS FOR THE PREPARATION OF CLOBETASOL 17-ESTERS AND COMPOUNDS OBTAINED.Info
- Publication number
- IT8320334A0 IT8320334A0 IT8320334A IT2033483A IT8320334A0 IT 8320334 A0 IT8320334 A0 IT 8320334A0 IT 8320334 A IT8320334 A IT 8320334A IT 2033483 A IT2033483 A IT 2033483A IT 8320334 A0 IT8320334 A0 IT 8320334A0
- Authority
- IT
- Italy
- Prior art keywords
- clobetasol
- esters
- preparation
- compounds obtained
- compounds
- Prior art date
Links
- FCSHDIVRCWTZOX-DVTGEIKXSA-N clobetasol Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@H](C)[C@@](C(=O)CCl)(O)[C@@]1(C)C[C@@H]2O FCSHDIVRCWTZOX-DVTGEIKXSA-N 0.000 title 1
- 229960002842 clobetasol Drugs 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/001—Oxiranes
- C07J71/0015—Oxiranes at position 9(11)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
- C07J7/0085—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (11)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT20334/83A IT1194178B (en) | 1983-03-29 | 1983-03-29 | PROCESS FOR THE PREPARATION OF 17-ESTERS OF CLOBETASOLO AND COMPOUNDS OBTAINED |
NO840065A NO840065L (en) | 1983-03-29 | 1984-01-09 | PROCEDURE FOR THE PREPARATION OF 17-ESTERS OF CLOBETASOL |
CH113/84A CH661930A5 (en) | 1983-03-29 | 1984-01-10 | Process for the preparation of 17-esters of clobetasol |
SE8400145A SE8400145L (en) | 1983-03-29 | 1984-01-12 | PROCEDURE FOR THE PREPARATION OF 17-ESTERS OF CLOBETASOL |
CA000445603A CA1220468A (en) | 1983-03-29 | 1984-01-19 | Process for the production of 17-esters of clobetasol |
FI840344A FI840344A (en) | 1983-03-29 | 1984-01-27 | FOERFARANDE FOER FRAMSTAELLNING AV 17- ESTRAR AV CLOBETASOL. |
JP59015956A JPS59205397A (en) | 1983-03-29 | 1984-01-31 | Manufacture of 17-ester of clobetasol |
JP59015957A JPS59205399A (en) | 1983-03-29 | 1984-01-31 | 17-ester of 21-chloro-9beta, 11beta-epoxy- 17-hydroxy-16beta-methylpregn-1,4-dien-3,20- dione and manufacture |
DK42884A DK42884A (en) | 1983-03-29 | 1984-01-31 | PROCEDURE FOR THE PREPARATION OF 17-ESTERS OF CLOBETASOL |
NL8400910A NL8400910A (en) | 1983-03-29 | 1984-03-22 | 17-ESTERS OF CLOBETASOL AND METHOD FOR PREPARING THE SAME |
YU00546/84A YU54684A (en) | 1983-03-29 | 1984-03-28 | Process for making 17-esthers of clobetasol |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT20334/83A IT1194178B (en) | 1983-03-29 | 1983-03-29 | PROCESS FOR THE PREPARATION OF 17-ESTERS OF CLOBETASOLO AND COMPOUNDS OBTAINED |
Publications (2)
Publication Number | Publication Date |
---|---|
IT8320334A0 true IT8320334A0 (en) | 1983-03-29 |
IT1194178B IT1194178B (en) | 1988-09-14 |
Family
ID=11165811
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT20334/83A IT1194178B (en) | 1983-03-29 | 1983-03-29 | PROCESS FOR THE PREPARATION OF 17-ESTERS OF CLOBETASOLO AND COMPOUNDS OBTAINED |
Country Status (10)
Country | Link |
---|---|
JP (2) | JPS59205399A (en) |
CA (1) | CA1220468A (en) |
CH (1) | CH661930A5 (en) |
DK (1) | DK42884A (en) |
FI (1) | FI840344A (en) |
IT (1) | IT1194178B (en) |
NL (1) | NL8400910A (en) |
NO (1) | NO840065L (en) |
SE (1) | SE8400145L (en) |
YU (1) | YU54684A (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN108727458A (en) * | 2018-05-10 | 2018-11-02 | 浙江仙居仙乐药业有限公司 | A kind of synthetic method of 17- propionic esters |
CN111944002A (en) * | 2020-07-29 | 2020-11-17 | 河南利华制药有限公司 | Beclomethasone dipropionate intermediate and preparation method thereof |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1253831A (en) * | 1968-01-19 | 1971-11-17 | Glaxo Lab Ltd | 9alpha,21-DIHALOPREGNANE COMPOUNDS |
JPS51125372A (en) * | 1975-03-31 | 1976-11-01 | Taisho Pharmaceut Co Ltd | Aprocess for preparing pregnane steroid-17-ester-21-halides |
-
1983
- 1983-03-29 IT IT20334/83A patent/IT1194178B/en active
-
1984
- 1984-01-09 NO NO840065A patent/NO840065L/en unknown
- 1984-01-10 CH CH113/84A patent/CH661930A5/en not_active IP Right Cessation
- 1984-01-12 SE SE8400145A patent/SE8400145L/en not_active Application Discontinuation
- 1984-01-19 CA CA000445603A patent/CA1220468A/en not_active Expired
- 1984-01-27 FI FI840344A patent/FI840344A/en not_active Application Discontinuation
- 1984-01-31 JP JP59015957A patent/JPS59205399A/en active Granted
- 1984-01-31 DK DK42884A patent/DK42884A/en not_active Application Discontinuation
- 1984-01-31 JP JP59015956A patent/JPS59205397A/en active Pending
- 1984-03-22 NL NL8400910A patent/NL8400910A/en not_active Application Discontinuation
- 1984-03-28 YU YU00546/84A patent/YU54684A/en unknown
Also Published As
Publication number | Publication date |
---|---|
FI840344A0 (en) | 1984-01-27 |
JPS59205399A (en) | 1984-11-20 |
JPS6228160B2 (en) | 1987-06-18 |
NL8400910A (en) | 1984-10-16 |
SE8400145D0 (en) | 1984-01-12 |
NO840065L (en) | 1984-10-01 |
DK42884D0 (en) | 1984-01-31 |
CH661930A5 (en) | 1987-08-31 |
SE8400145L (en) | 1984-09-30 |
JPS59205397A (en) | 1984-11-20 |
YU54684A (en) | 1986-10-31 |
IT1194178B (en) | 1988-09-14 |
CA1220468A (en) | 1987-04-14 |
DK42884A (en) | 1984-09-30 |
FI840344A (en) | 1984-09-30 |
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