IT8319737A0 - Ursodesossicolico solfato acido sale sodico. - Google Patents
Ursodesossicolico solfato acido sale sodico.Info
- Publication number
- IT8319737A0 IT8319737A0 IT8319737A IT1973783A IT8319737A0 IT 8319737 A0 IT8319737 A0 IT 8319737A0 IT 8319737 A IT8319737 A IT 8319737A IT 1973783 A IT1973783 A IT 1973783A IT 8319737 A0 IT8319737 A0 IT 8319737A0
- Authority
- IT
- Italy
- Prior art keywords
- sodium salt
- sulfate sodium
- ursodeoxycholic acid
- acid sulfate
- ursodeoxycholic
- Prior art date
Links
- RUDATBOHQWOJDD-UHFFFAOYSA-N (3beta,5beta,7alpha)-3,7-Dihydroxycholan-24-oic acid Natural products OC1CC2CC(O)CCC2(C)C2C1C1CCC(C(CCC(O)=O)C)C1(C)CC2 RUDATBOHQWOJDD-UHFFFAOYSA-N 0.000 title 1
- PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 title 1
- RUDATBOHQWOJDD-UZVSRGJWSA-N ursodeoxycholic acid Chemical compound C([C@H]1C[C@@H]2O)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC(O)=O)C)[C@@]2(C)CC1 RUDATBOHQWOJDD-UZVSRGJWSA-N 0.000 title 1
- 229960001661 ursodiol Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
- C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Gastroenterology & Hepatology (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT19737/83A IT1221734B (it) | 1983-02-24 | 1983-02-24 | Ursodesossicolico solfato acido sale sodico |
AT84200102T ATE21909T1 (de) | 1983-02-24 | 1984-01-27 | Natriumsalz von ursodeoxy-cholsaeuresulfat. |
DE8484200102T DE3460577D1 (en) | 1983-02-24 | 1984-01-27 | Sodium salt of ursodeoxycholic sulphate |
EP84200102A EP0117570B1 (en) | 1983-02-24 | 1984-01-27 | Sodium salt of ursodeoxycholic sulphate |
US06/582,522 US4565811A (en) | 1983-02-24 | 1984-02-22 | Sodium salt of ursodeoxycholic sulphate |
JP59034125A JPS59163400A (ja) | 1983-02-24 | 1984-02-23 | ウルソデソキシコ−ル酸硫酸エステルのナトリウム塩 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT19737/83A IT1221734B (it) | 1983-02-24 | 1983-02-24 | Ursodesossicolico solfato acido sale sodico |
Publications (2)
Publication Number | Publication Date |
---|---|
IT8319737A0 true IT8319737A0 (it) | 1983-02-24 |
IT1221734B IT1221734B (it) | 1990-07-12 |
Family
ID=11160798
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT19737/83A IT1221734B (it) | 1983-02-24 | 1983-02-24 | Ursodesossicolico solfato acido sale sodico |
Country Status (6)
Country | Link |
---|---|
US (1) | US4565811A (it) |
EP (1) | EP0117570B1 (it) |
JP (1) | JPS59163400A (it) |
AT (1) | ATE21909T1 (it) |
DE (1) | DE3460577D1 (it) |
IT (1) | IT1221734B (it) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4892868A (en) * | 1984-08-17 | 1990-01-09 | Gipharmex, S.P.A. | Derivatives of biliary acids, process for the production thereof and corresponding pharmaceutical compositions |
WO1994020520A1 (en) * | 1993-03-10 | 1994-09-15 | Magainin Pharmaceuticals Inc. | Steroid derivatives, pharmaceutical compositions containing them, and their use as antibiotics or disinfectants |
DE4334823C2 (de) * | 1993-10-09 | 1998-09-17 | Schering Ag | Verfahren zur Herstellung von Schwefelsäurehalbestern von Estrogenen |
US5840740A (en) * | 1995-06-07 | 1998-11-24 | Magainin Pharmaceuticals Inc. | Aminosterol compounds and a method of treating infection using the aminosterol compounds |
US5856535A (en) * | 1994-08-18 | 1999-01-05 | Magainin Pharmaceuticals, Inc. | Aminosterol ester compounds |
US5763430A (en) * | 1995-06-07 | 1998-06-09 | Magainin Pharmaceuticals Inc. | Method of treating a viral infection by administering a steroid compound |
US5874597A (en) * | 1995-06-07 | 1999-02-23 | Magainin Pharmaceuticals, Inc. | Certain aminosterol compounds and pharmaceutical compositions including these compounds |
US5847172A (en) * | 1995-06-07 | 1998-12-08 | Magainin Pharmaceuticals Inc. | Certain aminosterol compounds and pharmaceutical compositions including these compounds |
US5840936A (en) * | 1995-06-07 | 1998-11-24 | Magainin Pharmaceuticals Inc. | Aminosterol compounds useful as inhibitors of the sodium/proton exchanger (NHE) |
US5792635A (en) * | 1995-06-07 | 1998-08-11 | Magainin Pharmaceuticals, Inc. | Method of inhibiting the sodium/proton exchanger NHE3 and method of inhibiting growth by administering squalamine |
US5795885A (en) * | 1995-06-07 | 1998-08-18 | Magainin Pharmaceuticals Inc. | Method of inhibiting profileration of cells by administering an aminosterol compound |
US5994336A (en) * | 1995-06-07 | 1999-11-30 | Magainin Pharmaceuticals Inc. | Method of inhibiting proliferation of cells by administering an aminosterol compound |
US6143738A (en) * | 1995-06-07 | 2000-11-07 | Magainin Pharmaceuticals, Inc. | Therapeutic uses for an aminosterol compound |
US5763435A (en) * | 1995-11-21 | 1998-06-09 | Children's Hospital Medical Center | Sulfate conjugates of ursodeoxycholic acid, and their beneficial use in inflammatory disorders |
IT1283225B1 (it) | 1996-03-11 | 1998-04-16 | Renata Maria Anna Ve Cavaliere | Ceppi di batteri, composizione farmaceutica contenente uno o piu' di tali ceppi e uso dei medesimi per la prevenzione e la terapia delle |
US6596712B2 (en) | 1996-04-26 | 2003-07-22 | Genaera Corporation | Treatment of carcinomas using squalamine in combination with other anti-cancer agents or modalities |
ES2201296T3 (es) * | 1996-04-26 | 2004-03-16 | Genaera Corporation | Escualmina en combinacion con otros farmacos anticancerigenos para el tratamiento de tumores. |
IN186119B (it) * | 1996-07-25 | 2001-06-23 | Lg Chemical Ltd | |
US6262283B1 (en) | 1996-12-06 | 2001-07-17 | Magainin Pharmaceuticals Inc. | Stereoselective synthesis of 24-hydroxylated compounds useful for the preparation of aminosterols, vitamin D analogs, and other compounds |
AU5342701A (en) * | 2000-04-12 | 2001-10-30 | Genaera Corp | A process for the preparation of 7.alpha.-hydroxy 3-aminosubstituted sterols using intermediates with an unprotected 7.alpha.-hydroxy group |
ITTO20020102A1 (it) * | 2002-02-06 | 2003-08-06 | Abc Ist Biolog Chem Spa | Procedimento per la preparazione dell'acido ursodesossicolico disolfato e suoi sali farmaceuticamente accettabili. |
ITMI20030822A1 (it) * | 2003-04-18 | 2004-10-19 | Erregierre Spa | Processo per la preparazione dell'acido ursodesossicolico |
IT1393095B1 (it) | 2009-02-19 | 2012-04-11 | Prodotti Chimici Alimentari | Processo per la sintesi del sale disodico dell'acido ursodesossicolico 3,7-disolfato. |
ITTO20111069A1 (it) * | 2011-11-21 | 2013-05-22 | Abc Farmaceutici S P A | Formulazione farmaceutica liquida palatabile, per uso orale, comprendente acido ursodesossicolico estere solforico. |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2444048B1 (it) * | 1978-12-15 | 1981-08-14 | Roussel Uclaf | |
JPS5772903A (en) * | 1980-10-27 | 1982-05-07 | Mitsubishi Petrochem Co Ltd | Pyrazole herbicide |
IT1167479B (it) * | 1981-07-24 | 1987-05-13 | Carlo Scolastico | Derivati dell'acido chenodesossicolico |
IT1150756B (it) * | 1982-04-02 | 1986-12-17 | Zambon Spa | Procedimento per preparare l'acido 3alfa, 7beta-diidrossi-5beta-colanico |
-
1983
- 1983-02-24 IT IT19737/83A patent/IT1221734B/it active
-
1984
- 1984-01-27 DE DE8484200102T patent/DE3460577D1/de not_active Expired
- 1984-01-27 AT AT84200102T patent/ATE21909T1/de not_active IP Right Cessation
- 1984-01-27 EP EP84200102A patent/EP0117570B1/en not_active Expired
- 1984-02-22 US US06/582,522 patent/US4565811A/en not_active Expired - Lifetime
- 1984-02-23 JP JP59034125A patent/JPS59163400A/ja active Granted
Also Published As
Publication number | Publication date |
---|---|
JPH0137398B2 (it) | 1989-08-07 |
EP0117570B1 (en) | 1986-09-03 |
IT1221734B (it) | 1990-07-12 |
JPS59163400A (ja) | 1984-09-14 |
US4565811A (en) | 1986-01-21 |
EP0117570A1 (en) | 1984-09-05 |
DE3460577D1 (en) | 1986-10-09 |
ATE21909T1 (de) | 1986-09-15 |
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