IT8119082A0 - SEMI-SYNTHETIC MACROLIDE ANTIBIOTICS, MICROBIOLOGICAL PROCEDURE FOR THEIR PREPARATION AND RELATED MICROORGANISM, INTERMEDIATE FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM - Google Patents

SEMI-SYNTHETIC MACROLIDE ANTIBIOTICS, MICROBIOLOGICAL PROCEDURE FOR THEIR PREPARATION AND RELATED MICROORGANISM, INTERMEDIATE FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN THEM

Info

Publication number
IT8119082A0
IT8119082A0 IT8119082A IT1908281A IT8119082A0 IT 8119082 A0 IT8119082 A0 IT 8119082A0 IT 8119082 A IT8119082 A IT 8119082A IT 1908281 A IT1908281 A IT 1908281A IT 8119082 A0 IT8119082 A0 IT 8119082A0
Authority
IT
Italy
Prior art keywords
preparation
semi
contain
pharmaceutical compositions
macrolide antibiotics
Prior art date
Application number
IT8119082A
Other languages
Italian (it)
Other versions
IT1190651B (en
Inventor
Luciano Toscano
Leonardo Cappelletti
Original Assignee
Pierrel Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pierrel Spa filed Critical Pierrel Spa
Publication of IT8119082A0 publication Critical patent/IT8119082A0/en
Priority to IT8119082A priority Critical patent/IT1190651B/en
Priority to DE8282200019T priority patent/DE3268339D1/en
Priority to AT82200019T priority patent/ATE17351T1/en
Priority to CH98/82A priority patent/CH658250A5/en
Priority to US06/338,105 priority patent/US4439426A/en
Priority to BE0/207019A priority patent/BE891734A/en
Priority to EP82200019A priority patent/EP0056291B1/en
Priority to FR8200187A priority patent/FR2502155A1/en
Priority to CA000393832A priority patent/CA1169375A/en
Priority to FI820057A priority patent/FI72346C/en
Priority to JP57002180A priority patent/JPS57140779A/en
Priority to FI834570A priority patent/FI80688C/en
Priority to US06/570,833 priority patent/US4540662A/en
Priority to CA000452649A priority patent/CA1189856A/en
Application granted granted Critical
Publication of IT1190651B publication Critical patent/IT1190651B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/08Bridged systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D313/00Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08Hetero rings containing eight or more ring members, e.g. erythromycins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/44Preparation of O-glycosides, e.g. glucosides
    • C12P19/60Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
    • C12P19/62Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465Streptomyces
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465Streptomyces
    • C12R2001/48Streptomyces antibioticus ; Actinomyces antibioticus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oncology (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
IT8119082A 1981-01-09 1981-01-09 SEMI-SYNTHETIC MACROLIDIC ANTIBIOTICS, MICROBIOLOGICAL PROCEDURE FOR THEIR PREPARATION AND RELATIVE MICROORGANISM, INTERMEDIATE FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM IT1190651B (en)

Priority Applications (14)

Application Number Priority Date Filing Date Title
IT8119082A IT1190651B (en) 1981-01-09 1981-01-09 SEMI-SYNTHETIC MACROLIDIC ANTIBIOTICS, MICROBIOLOGICAL PROCEDURE FOR THEIR PREPARATION AND RELATIVE MICROORGANISM, INTERMEDIATE FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
EP82200019A EP0056291B1 (en) 1981-01-09 1982-01-08 Novel semisynthetic macrolidic antibiotics, microbiological processes for their preparation and related microorganism, novel intermediate compounds for their preparation and related pharmaceutical compositions containing them
CA000393832A CA1169375A (en) 1981-01-09 1982-01-08 Semisynthetic macrolidic antibiotics, microbiological process for their preparation and related microorganism, novel intermediate compounds for their preparation and related pharmaceutical compositions containing them
CH98/82A CH658250A5 (en) 1981-01-09 1982-01-08 NEW SEMI-SYNTHETIC MACROLIDIC ANTIBIOTICS, MICROBIOLOGICAL PROCEDURES FOR THEIR PREPARATION NEW INTERMEDIATES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.
US06/338,105 US4439426A (en) 1981-01-09 1982-01-08 Semisynthetic macrolidic antibiotics, intermediate compounds for their preparation and related pharmaceutical compositions containing them
BE0/207019A BE891734A (en) 1981-01-09 1982-01-08 MACROLIDE ANTIBIOTICS, PROCESS FOR THEIR PREPARATION AND RELATED MICROORGANISMS, THEIR INTERMEDIATE PRODUCTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
DE8282200019T DE3268339D1 (en) 1981-01-09 1982-01-08 Novel semisynthetic macrolidic antibiotics, microbiological processes for their preparation and related microorganism, novel intermediate compounds for their preparation and related pharmaceutical compositions containing them
FR8200187A FR2502155A1 (en) 1981-01-09 1982-01-08 NOVEL SEMI-SYNTHETIC MACROLIDE ANTIBIOTICS, MICROBIOLOGICAL PROCESS FOR THE PREPARATION THEREOF AND MICROORGANISM THEREFOR, NOVEL INTERMEDIATE PRODUCTS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME
AT82200019T ATE17351T1 (en) 1981-01-09 1982-01-08 SEMISYNTHETIC MACROLIDS ANTIBIOTICS, PROCESSES FOR THEIR MICROBIOLOGICAL PRODUCTION, THEIR PHARMACEUTICAL COMPOSITIONS, RELATED MICROORGANISMS AND INTERMEDIATE COMPOUNDS FOR THEIR REPRESENTATION.
FI820057A FI72346C (en) 1981-01-09 1982-01-08 SAETT ATT FRAMSTAELLA NYA CHEAP SYNTHETIC MACROIDANTIBIOTICS.
JP57002180A JPS57140779A (en) 1981-01-09 1982-01-09 Macrolide antibiotics, microbial production and relative microbes, novel intermediates and pharmaceutical composition
FI834570A FI80688C (en) 1981-01-09 1983-12-13 NY MELLANPRODUKT (8S) -8- FLUORERYTRONOLID A SOM AER ANVAENDBAR VID FRAMSTAELLNING AV HALVSYNETETISKA MACROLIDANTIBIOTIKA.
US06/570,833 US4540662A (en) 1981-01-09 1984-01-16 Semisynthetic macrolidic antibiotics, intermediate compounds for their preparation and related pharmaceutical compositions containing compounds for their preparation and related pharmaceutical compositions containing them
CA000452649A CA1189856A (en) 1981-01-09 1984-04-24 Semisynthetic macrolidic antibiotics, microbiological processes for their preparation and related microorganism, novel intermediate compounds for their preparation and related pharmaceutical compositions containing them

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8119082A IT1190651B (en) 1981-01-09 1981-01-09 SEMI-SYNTHETIC MACROLIDIC ANTIBIOTICS, MICROBIOLOGICAL PROCEDURE FOR THEIR PREPARATION AND RELATIVE MICROORGANISM, INTERMEDIATE FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Publications (2)

Publication Number Publication Date
IT8119082A0 true IT8119082A0 (en) 1981-01-09
IT1190651B IT1190651B (en) 1988-02-24

Family

ID=11154388

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8119082A IT1190651B (en) 1981-01-09 1981-01-09 SEMI-SYNTHETIC MACROLIDIC ANTIBIOTICS, MICROBIOLOGICAL PROCEDURE FOR THEIR PREPARATION AND RELATIVE MICROORGANISM, INTERMEDIATE FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

Country Status (3)

Country Link
JP (1) JPS57140779A (en)
BE (1) BE891734A (en)
IT (1) IT1190651B (en)

Also Published As

Publication number Publication date
JPH0224279B2 (en) 1990-05-29
BE891734A (en) 1982-04-30
IT1190651B (en) 1988-02-24
JPS57140779A (en) 1982-08-31

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