IT8022283A0 - 1-(4-CHLOROBENZHYDRIL)-4-(2,3-DIHYDROXYPROPYL)-PIPERAZINE, METHODS FOR ITS PREPARATION AND RELATED PHARMACEUTICAL COMPOSITIONS. - Google Patents
1-(4-CHLOROBENZHYDRIL)-4-(2,3-DIHYDROXYPROPYL)-PIPERAZINE, METHODS FOR ITS PREPARATION AND RELATED PHARMACEUTICAL COMPOSITIONS.Info
- Publication number
- IT8022283A0 IT8022283A0 IT8022283A IT2228380A IT8022283A0 IT 8022283 A0 IT8022283 A0 IT 8022283A0 IT 8022283 A IT8022283 A IT 8022283A IT 2228380 A IT2228380 A IT 2228380A IT 8022283 A0 IT8022283 A0 IT 8022283A0
- Authority
- IT
- Italy
- Prior art keywords
- chlorobenzhydril
- dihydroxypropyl
- piperazine
- preparation
- methods
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
- C07D295/073—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
- C07D295/205—Radicals derived from carbonic acid
Priority Applications (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT22283/80A IT1140978B (en) | 1980-05-23 | 1980-05-23 | 1- (4-CHLOROBENZIDRIL) -4- (2,3-DIIDROS SIPROPIL) -PIPERAZINE, METHODS FOR ITS PREPARATION AND RELATED PHARMACEUTICAL COMPOSITION |
DE3118162A DE3118162C2 (en) | 1980-05-23 | 1981-05-07 | 1- (4-chlorobenzhydryl) -4- (2,3-bis-hydroxypropyl) -piperazine, its salts, process for their preparation and medicament containing these compounds |
FR8109273A FR2482965A1 (en) | 1980-05-23 | 1981-05-08 | 1- (4-CHLOROBENZHYDRYL) -4- (2,3-DIHYDROXYPROPYL) -PIPERAZINE, ITS PREPARATION METHOD AND ITS THERAPEUTIC APPLICATION |
NL8102361A NL8102361A (en) | 1980-05-23 | 1981-05-13 | 1- (4-CHLOROBENZHYDRYL) -4- (2,3-BIS-HYDROXYPROPYL) -PIPERAZINE, HAVE BEEN USED AS ANTI-COUGHING AGENT, ANTI-HISTAMINIC, SEDATIVE, ANALGETIC AND ANTI-INFLAMMATIVE PREPARATOR, WITH THIS FARM. |
BE2/59160A BE888811A (en) | 1980-05-23 | 1981-05-15 | 1- (4-CHLOROBENZHYDRYL) -4- (2,3-BIS-HYDROXYPROPYL) -PIPERAZINE, HAVE BEEN USED AS ANTI-COVERAGE, ANTI-HISTAMINIC SEDATIVE, ANALGETIC AND ANTI-INFLAMMATIVE PREPARATOR, WITH FARM PRODUCT. |
ES502429A ES502429A0 (en) | 1980-05-23 | 1981-05-22 | PROCEDURE FOR THE PREPARATION OF 1- (4-CHLOROBENCIDRIL) -4- (2,3-DIHIDROXIPROPIL) -PIPERACINE |
GB8115827A GB2076403B (en) | 1980-05-23 | 1981-05-22 | 1-(4-chlorobenzhydryl)-4-(2,3-bishydrocypropyl) piperazine |
JP7856281A JPS5731678A (en) | 1980-05-23 | 1981-05-23 | 1-(4-chlorobenzhydryl)-4-(2,3-bishydroxypropyl)- piperazine, manufacture and medicinal composition as effective component thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT22283/80A IT1140978B (en) | 1980-05-23 | 1980-05-23 | 1- (4-CHLOROBENZIDRIL) -4- (2,3-DIIDROS SIPROPIL) -PIPERAZINE, METHODS FOR ITS PREPARATION AND RELATED PHARMACEUTICAL COMPOSITION |
Publications (2)
Publication Number | Publication Date |
---|---|
IT8022283A0 true IT8022283A0 (en) | 1980-05-23 |
IT1140978B IT1140978B (en) | 1986-10-10 |
Family
ID=11194137
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT22283/80A IT1140978B (en) | 1980-05-23 | 1980-05-23 | 1- (4-CHLOROBENZIDRIL) -4- (2,3-DIIDROS SIPROPIL) -PIPERAZINE, METHODS FOR ITS PREPARATION AND RELATED PHARMACEUTICAL COMPOSITION |
Country Status (8)
Country | Link |
---|---|
JP (1) | JPS5731678A (en) |
BE (1) | BE888811A (en) |
DE (1) | DE3118162C2 (en) |
ES (1) | ES502429A0 (en) |
FR (1) | FR2482965A1 (en) |
GB (1) | GB2076403B (en) |
IT (1) | IT1140978B (en) |
NL (1) | NL8102361A (en) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3611276A1 (en) * | 1986-04-04 | 1987-11-26 | Unilever Nv | PACKING WITH MARGARINE OR SIMILAR BREAD |
JPH01226575A (en) * | 1988-02-25 | 1989-09-11 | Mitsubishi Plastics Ind Ltd | Packed body of seaweed |
SE9504661D0 (en) * | 1995-12-22 | 1995-12-22 | Astra Pharma Inc | New compounds |
SE9904674D0 (en) | 1999-12-20 | 1999-12-20 | Astra Pharma Inc | Novel compounds |
SE9904673D0 (en) | 1999-12-20 | 1999-12-20 | Astra Pharma Inc | Novel compounds |
SE0001209D0 (en) | 2000-04-04 | 2000-04-04 | Astrazeneca Canada Inc | Novel compounds |
NZ539828A (en) | 2001-05-18 | 2007-01-26 | Astrazeneca Ab | 4 (phenyl-piperazinyl-methyl) benzamide derivatives and their use for the treatment of pain, anxiety or gastrointestinal disorders |
SE0203302D0 (en) | 2002-11-07 | 2002-11-07 | Astrazeneca Ab | Novel Compounds |
SE0203300D0 (en) | 2002-11-07 | 2002-11-07 | Astrazeneca Ab | Novel Compounds |
SE0203303D0 (en) | 2002-11-07 | 2002-11-07 | Astrazeneca Ab | Novel Compounds |
MX2007001240A (en) | 2004-08-02 | 2007-03-23 | Astrazeneca Ab | Diarylmethyl piperazine derivatives, preparations thereof and uses thereof. |
HU227074B1 (en) | 2005-12-08 | 2010-06-28 | Egis Gyogyszergyar Nyrt | An optically active carbamic acid derivative, method for producing the same and use as a pharmaceutical intermediate |
US7989623B2 (en) | 2007-11-21 | 2011-08-02 | Synthon Bv | Process for making n-(diphenylmethyl)piperazines |
PL2062881T3 (en) * | 2007-11-21 | 2011-07-29 | Synthon Bv | Process for making N-(diphenylmethyl)piperazines |
-
1980
- 1980-05-23 IT IT22283/80A patent/IT1140978B/en active
-
1981
- 1981-05-07 DE DE3118162A patent/DE3118162C2/en not_active Expired
- 1981-05-08 FR FR8109273A patent/FR2482965A1/en active Granted
- 1981-05-13 NL NL8102361A patent/NL8102361A/en not_active Application Discontinuation
- 1981-05-15 BE BE2/59160A patent/BE888811A/en not_active IP Right Cessation
- 1981-05-22 ES ES502429A patent/ES502429A0/en active Granted
- 1981-05-22 GB GB8115827A patent/GB2076403B/en not_active Expired
- 1981-05-23 JP JP7856281A patent/JPS5731678A/en active Granted
Also Published As
Publication number | Publication date |
---|---|
ES8203352A1 (en) | 1982-04-01 |
GB2076403A (en) | 1981-12-02 |
GB2076403B (en) | 1983-11-16 |
JPS6135189B2 (en) | 1986-08-12 |
FR2482965A1 (en) | 1981-11-27 |
NL8102361A (en) | 1981-12-16 |
ES502429A0 (en) | 1982-04-01 |
DE3118162C2 (en) | 1984-07-26 |
IT1140978B (en) | 1986-10-10 |
BE888811A (en) | 1981-08-28 |
JPS5731678A (en) | 1982-02-20 |
DE3118162A1 (en) | 1982-02-18 |
FR2482965B1 (en) | 1984-11-23 |
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